Targeting natural killer cells to enhance HIV vaccine responses
08/01/2019 - 07/31/2024
Goal is to garner mechanistic insights into NK-cell suppression of vaccine responses and develop clinically translatable methods for overcoming this roadblock to enhance development of HIV-1 antibodies.
Transcription Factor Genetics in Lupus
04/01/2019 - 03/31/2024
This project aims to provide mechanistic insights into the molecular contributions of coding and non-coding lupus genetic risk variants to control of gene expression by transcription factors.
Genetics of organ-specific lupus disease sequelae
07/01/2020 - 06/30/2022
Goal is to use inducible models of lupus in the collaborative cross resource to identify genetic loci that dictate susceptibility to specific organ manifestations of lupus.