Waggoner Lab

Waggoner SN, Daniels KA, Welsh RM. Therapeutic depletion of natural killer cells controls persistent infection. The Journal of Virology. 2014 Feb;88(4):1953-60.

B. Severa M, Islam SA, Waggoner SN, Jiang Z, Kim ND, Ryan G, Kurt-Jones E, Charo I, Caffrey DR, Boyartchuk VL, Luster AD, Fitzgerald KA. The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8. The Journal of Immunology. 2014 Mar 1;192(5):2291-304. 

Cornberg M, Kenney LL, Chen AT, Waggoner SN, Kim SK, Dienes HP, Welsh RM, Selin LK. Clonal exhaustion as a mechanism to protect against severe immunopathology and death from an overwhelming CD8 T cell response. Frontiers in Immunological Memory. 2013 Dec 20;4:475.

Welsh RM, Waggoner SN. NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections. Virology. 2013 Jan 5;435(1):37-45.

Waggoner SN, Cornberg M, Selin LK, Welsh RM. Natural killer cells act as rheostats modulating anti-viral T cells. Nature. 2011 Nov 20;481(7381):394-8.*
* This paper is “Faculty of 1000 recommended” at: http://f1000.com/13414956.

Waggoner SN, Taniguchi RT, Mathew PA, Kumar V, Welsh RM. Absence of mouse 2B4 promotes NK cell–mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis. Journal of Clinical Investigation. 2010 Jun;120(6):1925-38.

Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN,  Szomolanyi-Tsuda E, Fitzgerald KA. The AIM2inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nature Immunology. 2010 May;11(5):395-402.