Waggoner Lab
Publications

Publications

Mukhopadhyay, E; Lakes, N; Krishnamurthy, D; Tuazon, JA; Ohayon, DE; Ali, A; Seelamneni, H; Lee, LH; Hildeman, DA; Waggoner, SN. RNA helicase DDX3X promotes NK cell survival by supporting MCL1 expression. Journal of Immunology. 2025; 214(12):3218-3227.

Canaday, LM; Cox, A; Feldman, HA; Seelamneni, H; Ali, A; Tuazon, JA; Botero Calderon, L; Bennett, SN; Yan, A; Wilson, M; Velu, V; Waggoner, SN. Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection. Journal of Immunology. 2025; 214(8):1917-1925.

Cantrell, R; Feldman, HA; Rosenfeldt, L; Ali, A; Gourley, B; Sprague, C; Leino, D; Crosby, J; Revenko, A; Monia, B; Waggoner, SN; Palumbo, JS. Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice. JCI Insight. 2025; 10(4).

Ochayon, DE; Devore, SB; Chang, W-C; Krishnamurthy, D; Seelamneni, H; Grashel, B; Spagna, D; Andorf, S; Martin, LJ; Biagini, JM; Waggoner, SN; Khurana Hershey, GK. Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early childhood severe atopic dermatitis. Science immunology. 2024; 9(92):eadd3085.

Ali, A; Canaday, LM; Feldman, HA; Cevik, H; Moran, MT; Rajaram, S; Lakes, N; Tuazon, JA; Seelamneni, H; Krishnamurthy, D; Blass, E; Barouch, DH; Waggoner, SN. Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues. Journal of Clinical Investigation. 2021; 131(18).

Reighard, SD; Cranert, SA; Rangel, KM; Ali, A; Gyurova, IE; De La Cruz-Lynch, AT; Tuazon, JA; Khodoun, MV; Kottyan, LC; Smith, DF; Brunner, HI; Waggoner, SN. Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells. Cell Reports Medicine. 2020; 1(1).

Ochayon, DE; Ali, A; Alarcon, PC; Krishnamurthy, D; Kottyan, LC; Borchers, MT; Waggoner, SN. IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells. Journal of Leukocyte Biology. 2020; 107(4):663-671.

Gyurova, IE; Schlums, H; Sucharew, H; Ambroggio, L; Ochayon, DE; Win, HT; Bryceson, YT; Bernstein, DI; Waggoner, SN. Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection. Frontiers in Immunology. 2019; 10:2728.

Rydyznski, CE; Cranert, SA; Zhou, JQ; Xu, H; Kleinstein, SH; Singh, H; Waggoner, SN. Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal Centers. Cell reports. 2018; 24(13):3367-3373.e4.

Rydyznski, C; Daniels, KA; Karmele, EP; Brooks, TR; Mahl, SE; Moran, MT; Li, C; Sutiwisesak, R; Welsh, RM; Waggoner, SN. Generation of cellular immune memory and B-cell immunity is impaired by natural killer cells. Nature Communications. 2015; 6:6375.

Mukhopadhyay, E; Lakes, N; Krishnamurthy, D; Tuazon, JA; Ohayon, DE; Ali, A; Seelamneni, H; Lee, LH; Hildeman, DA; Waggoner, SN. RNA helicase DDX3X promotes NK cell survival by supporting MCL1 expression. Journal of Immunology. 2025; 214(12):3218-3227.

Alshwimi, AO; Chimote, AA; Khodoun, MV; Weatherford, L; Hinrichs, BH; Wulff, H; Waggoner, SN; Wise-Draper, TM; Conforti, L. KCa3.1 channels regulate the tumor infiltration of functionally competent NK cells in head and neck cancer. Scientific Reports. 2025; 15(1):36360.

Canaday, LM; Cox, A; Feldman, HA; Seelamneni, H; Ali, A; Tuazon, JA; Botero Calderon, L; Bennett, SN; Yan, A; Wilson, M; Velu, V; Waggoner, SN. Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection. Journal of Immunology. 2025; 214(8):1917-1925.

Vasilyeva, V; Makinson, O; Chan, C; Park, M; O'dwyer, C; Ali, A; Khan, AUH; De Souza, CT; Hasim, MS; Asif, S; Sciumè, G; Waggoner, S; Ardolino, M; Marotel, M. LAG3 Marks Activated but Hyporesponsive NK Cells. European Journal of Immunology. 2025; 55(7):e70009.

Cantrell, R; Feldman, HA; Rosenfeldt, L; Ali, A; Gourley, B; Sprague, C; Leino, D; Crosby, J; Revenko, A; Monia, B; Waggoner, SN; Palumbo, JS. Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice. JCI Insight. 2025; 10(4).

Valbon, SF; Lebel, M-E; Feldman, HA; Condotta, SA; Dong, M; Giordano, D; Waggoner, SN; Melichar, HJ; Richer, MJ. Type I interferon induced during chronic viral infection favors B-cell development in the thymus. Immunology and Cell Biology. 2024; 102(9):801-816.

Ochayon, DE; Devore, SB; Chang, W-C; Krishnamurthy, D; Seelamneni, H; Grashel, B; Spagna, D; Andorf, S; Martin, LJ; Biagini, JM; Waggoner, SN; Khurana Hershey, GK. Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early childhood severe atopic dermatitis. Science immunology. 2024; 9(92):eadd3085.

Burkes, RM; Bailey, E; Hwalek, T; Osterburg, A; Lach, L; Panos, R; Waggoner, SN; Borchers, MT. Associations of Smoking, Cytomegalovirus Serostatus, and Natural Killer Cell Phenotypes in Smokers With and At Risk for COPD. Chronic Obstructive Pulmonary Diseases. 2023; 10(3):286-296.

Lakes, N; Canaday, LM; Waggoner, SN. Can't drop the MIC(A/B): Preventing stress-ligand shedding to enhance pan-cancer targeting. Med. 2023; 4(7):398-400.

Feldman, HA; Cevik, H; Waggoner, SN. Negativity begets longevity in T cells. Journal of Clinical Investigation. 2023; 133(12).

Le, H; Spearman, P; Waggoner, SN; Singh, K. Ebola virus protein VP40 stimulates IL-12- and IL-18-dependent activation of human natural killer cells. JCI Insight. 2022; 7(16).

Rahman, SA; Billingsley, JM; Sharma, AA; Styles, TM; Govindaraj, S; Shanmugasundaram, U; Babu, H; Riberio, SP; Ali, SA; Tharp, GK; Villinger, F; Bosinger, SE; Amara, RR; Velu, V. Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection. JCI Insight. 2022; 7(8).

Rao, R; Han, R; Ogurek, S; Xue, C; Wu, LM; Zhang, L; Zhang, L; Hu, J; Phoenix, TN; Waggoner, SN; Lu, QR. Glioblastoma genetic drivers dictate the function of tumor-associated macrophages/microglia and responses to CSF1R inhibition. Neuro-Oncology. 2022; 24(4):584-597.

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