Center for Autoimmune Genomics and Etiology (CAGE)
Publications

Publications

Armstrong, ND; Patki, A; Srinivasasainagendra, V; Ge, T; Lange, LA; Kottyan, L; Namjou, B; Shah, AS; Rasmussen-Torvik, LJ; Jarvik, GP; Meigs, JB; Karlson, EW; Limdi, NA; Irvin, MR; Tiwari, HK. Variant level heritability estimates of type 2 diabetes in African Americans. Scientific Reports. 2024; 14:14009.

Correia Marques, M; Rubin, D; Shuldiner, EG; Datta, M; Schmitz, E; Gutierrez Cruz, G; Patt, A; Bennett, E; Grom, A; Foell, D; Woo, P; Yeung, RS M; Zeft, AS; Zeggini, E. Enrichment of Rare Variants of Hemophagocytic Lymphohistiocytosis Genes in Systemic Juvenile Idiopathic Arthritis. Arthritis and Rheumatology. 2024; 76:1566-1572.

Ding, H; Shen, Y; Hong, SM; Xiang, C; Shen, N. Biomarkers for systemic lupus erythematosus - a focus on organ damage. Expert Review of Clinical Immunology. 2024; 20:39-58.

Greene, CA; Hampton, G; Jarvik, GP; Namjou-Khales, B; Khan, A; Luo, Y; Edwards, TL; Velez Edwards, DR; Hellwege, JN. 47 Cross-ancestry GWAS meta-analysis of keloids discovers novel susceptibility loci in diverse populations. Journal of Clinical and Translational Science. 2024; 8:13.

Hu, J; Korchina, V; Zouk, H; Harden, MV; Murdock, D; Macbeth, A; Harrison, SM; Lennon, N; Kovar, C; Balasubramanian, A; Hynes, ED; Johnson, DK; Jones, LK; Joo, YY. Genetic sex validation for sample tracking in next-generation sequencing clinical testing. BMC Research Notes. 2024; 17:62.

Igoe, A; Merjanah, S; Harley, IT W; Clark, DH; Sun, C; Kaufman, KM; Harley, JB; Kaelber, DC; Scofield, RH. Association between systemic lupus erythematosus and myasthenia gravis: A population-based National Study. Clinical Immunology. 2024; 260:109810.

Kurowski, BG; Treble-Barna, A; Pilipenko, V; Martin, LJ; Jegga, AG; Miley, AE; Zhang, N; Fabio, A; Chima, RS; Adlam, AL R; Kaufman, K; Bell, MJ; Beers, SR; Wisniewski, SR; Wade, SL. Elucidating a genomic signature associated with behavioral and executive function after moderate to severe pediatric TBI: a systems biology informed approach. Frontiers in Systems Biology. 2024; 4:1293265.

Lennon, NJ; Kottyan, LC; Kachulis, C; Abul-Husn, NS; Arias, J; Belbin, G; Below, JE; Berndt, SI; Chung, WK; Cimino, JJ; Weng, C; Wiesner, GL; Yin, X; Kenny, EE. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature Medicine. 2024; 30:480-487.

Marsili, L; Davis, JL; Espay, AJ; Gilthorpe, J; Williams, C; Kauffman, MA; Porollo, A. SOD1-Related Cerebellar Ataxia and Motor Neuron Disease: Cp Variant as Functional Modifier?. The Cerebellum: an international journal from neurosciences to clinical perspectives. 2024; 23:205-209.

Ochayon, DE; DeVore, SB; Chang, WC; Krishnamurthy, D; Seelamneni, H; Grashel, B; Spagna, D; Andorf, S; Martin, LJ; Biagini, JM; Waggoner, SN; Khurana Hershey, GK. Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early childhood severe atopic dermatitis. Science Immunology. 2024; 9:eadd3085.

Ojha, M; Smith, NJ; Devine, AJ; Joshi, R; Goodman, EM; Fan, Q; Schuman, R; Porollo, A; Wells, JM; Tiwary, E; Deshmukh, H; Borchers, MT; Ammerman, SA; Varisco, BM. Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling. JCI insight. 2024; 9:e169189.

Porollo, A; Sayson, SG; Ashbaugh, A; Rebholz, S; Landero Figueroa, JA; Cushion, MT. Insights into copper sensing and tolerance in Pneumocystis species. Frontiers in Microbiology. 2024; 15:1383737.

Sayson, SG; Ashbaugh, A; Porollo, A; Smulian, G; Cushion, MT. Pneumocystis murina promotes inflammasome formation and NETosis during Pneumocystis pneumonia. Editor, Nielsen K; Kolls J. mBio. 2024; 15:e0140924.

Valbon, SF; Lebel, ME; Feldman, HA; Condotta, SA; Dong, M; Giordano, D; Waggoner, SN; Melichar, HJ; Richer, MJ. Type I interferon induced during chronic viral infection favors B-cell development in the thymus. Immunology and Cell Biology. 2024; 102:801-816.

Viel, KC M F; Parameswaran, S; Donmez, OA; Forney, CR; Hass, MR; Yin, C; Jones, SH; Prosser, HK; Diouf, AA; Gittens, OE; Gewurz, B; Zhao, B; Kottyan, LC; Weirauch, MT. Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome. BMC Genomics. 2024; 25:273.

Virolainen, SJ; Satish, L; Biagini, JM; Chaib, H; Chang, WC; Dexheimer, PJ; Dixon, MR; Dunn, K; Fletcher, D; Forney, C; Shook, M; Weirauch, MT; Khurana Hershey, GK; Kottyan, LC. Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI insight. 2024; 9:e178258.

Wallach, I; Bernard, D; Nguyen, K; Ho, G; Morrison, A; Stecula, A; Rosnik, A; O’Sullivan, AM; Davtyan, A; Samudio, B; Lam, A; Cuddihy, AR; White, A; Taglialatela, A. AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. 2024; 14:7526.

Zhu, X; Zhang, Y; Yin, Z; Ye, Z; Qin, Y; Cheng, Z; Shen, Y; Yin, Z; Ma, J; Tang, Y; Ding, H; Guo, Y; Hou, G; Shen, N. Three-Dimensional Chromosomal Landscape Revealing miR-146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR-Mediated Approach to Inhibit the Interferon Pathway. Arthritis and Rheumatology. 2024; 76:384-395.