Publications

Alexandrou, E; Cabrera-Salcedo, C; Labilloy, G; Tyzinski, L; Smolarek, TA; Andrew, M; Huang, Y; Backeljauw, P; Dauber, A. (2020) Algorithm-Driven Electronic Health Record Notification Enhances the Detection of Turner Syndrome. Elsevier BV. 216:227-231.

Chan, CC; Damen, MS M A; Moreno-Fernandez, ME; Stankiewicz, TE; Cappelletti, M; Alarcon, PC; Oates, JR; Doll, JR; Mukherjee, R; Chen, X; et al. Type I interferon sensing unlocks dormant adipocyte inflammatory potential. Nature Communications. 2020; 11.

Ding, H; Lin, C; Cai, J; Guo, Q; Dai, M; Mohan, C; Shen, N. Urinary activated leukocyte cell adhesion molecule as a novel biomarker of lupus nephritis histology. Arthritis Research and Therapy. 2020; 22.

Eapen, A; Assa'ad, A. Asthma. In: Gupta R, Ed. Pediatric Food Allergy A Clinical Guide. Chan, Switzerland: Springer; 2020.

Elliott, KH; Chen, X; Salomone, J; Chaturvedi, P; Schultz, PA; Balchand, SK; Servetas, JD; Zuniga, A; Zeller, R; Gebelein, B; et al. Gli3 utilizes hand2 to synergistically regulate tissue-specific transcriptional networks. eLife. 2020; 9:1-33.

Ghodke-Puranik, Y; Imgruet, M; Dorschner, JM; Shrestha, P; McCoy, K; Kelly, JA; Marion, M; Guthridge, JM; Langefeld, CD; Harley, JB; et al. Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen. Cytokine. 2020; 132:154631-154631.

Glessner, JT; Li, J; Desai, A; Palmer, M; Kim, D; Lucas, AM; Chang, X; Connolly, JJ; Almogeura, B; Harley, JB; et al. CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease. International Journal of Cardiology. 2020; 298:107-113.

Gyurova, IE; Ali, A; Waggoner, SN. Natural Killer Cell Regulation of B Cell Responses in the Context of Viral Infection. Viral Immunology. 2020; 33:334-341.

He, J; Zhang, R; Shao, M; Zhao, X; Miao, M; Chen, J; Liu, J; Zhang, X; Zhang, X; Jin, Y; et al. Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial. Annals of the Rheumatic Diseases. 2020; 79:141-149.

Hong, S; Liu, C; Yin, Z; Wu, L; Qu, B; Shen, N. MicroRNAs in Systemic Lupus Erythematosus: a Perspective on the Path from Biological Discoveries to Clinical Practice. Current Rheumatology Reports. 2020; 22.

Javier, E; Lu, X; Kottyan, LC. Noncoding Variants as Genetic Contributors to Autoimmune Disease Pathogenesis. Journal of Investigative Dermatology. 2020; 140:277-278.

Jennings, EC; Korthauer, MW; Hendershot, JM; Bailey, ST; Weirauch, MT; Ribeiro, JM C; Benoit, JB. Molecular mechanisms underlying milk production and viviparity in the cockroach, Diploptera punctata. Insect Biochemistry and Molecular Biology. 2020; 120:103333-103333.

Jiang, K; Kessler, H; Park, Y; Sudman, M; Thompson, SD; Jarvis, JN. Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci. PLoS ONE. 2020; 15:e0235857-e0235857.

Jog, NR; McClain, MT; Heinlen, LD; Gross, T; Towner, R; Guthridge, JM; Axtell, RC; Pardo, G; Harley, JB; James, JA. Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model. Journal of Autoimmunity. 2020; 106:102332-102332.

Joo, YY; Actkins, K; Pacheco, JA; Basile, AO; Carroll, R; Crosslin, DR; Day, F; Denny, JC; Edwards, DR V; Hakonarson, H; et al. A polygenic and phenotypic risk prediction for polycystic ovary syndrome evaluated by phenomewide association studies. Journal of Clinical Endocrinology and Metabolism. 2020; 105:1918-1936.

Kamitaki, N; Sekar, A; Handsaker, RE; de Rivera, H; Tooley, K; Morris, DL; Taylor, KE; Whelan, CW; Tombleson, P; Loohuis, LM O; et al. Complement genes contribute sex-biased vulnerability in diverse disorders. Nature. 2020; 582:577-581.

Kawai, VK; Shi, M; Feng, Q; Chung, CP; Liu, G; Cox, NJ; Jarvik, GP; Lee, MT M; Hebbring, SJ; Harley, JB; et al. Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance–Weighted Meta-Analysis. Arthritis and Rheumatology. 2020; 72:1483-1492.

Kottyan, LC; Parameswaran, S; Weirauch, MT; Rothenberg, ME; Martin, LJ. The genetic etiology of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2020; 145:9-15.

Li, G; Ding, H; Yu, X; Meng, Y; Li, J; Guo, Q; Zhou, H; Shen, N. Spermidine Suppresses Inflammatory DC Function by Activating the FOXO3 Pathway and Counteracts Autoimmunity. iScience. 2020; 23:100807-100807.

Li, Y; Liao, Z; Luo, H; Benyoucef, A; Kang, Y; Lai, Q; Dovat, S; Miller, B; Chepelev, I; Li, Y; et al. Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis. Nucleic Acids Research. 2020; 48:3119-3133.

Liu, X; Hong, T; Parameswaran, S; Ernst, K; Marazzi, I; Weirauch, MT; Bass, JI F. Human Virus Transcriptional Regulators. Cell. 2020; 182:24-37.

Maezawa, S; Sakashita, A; Yukawa, M; Chen, X; Takahashi, K; Alavattam, KG; Nakata, I; Weirauch, MT; Barski, A; Namekawa, SH. Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition. Nature Structural and Molecular Biology. 2020; 27:978-988.

McDaniel, MM; Kottyan, LC; Singh, H; Pasare, C. Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming. Cell Reports. 2020; 31:107604-107604.

Meng, Y; Li, J; Ye, Z; Yin, Z; Sun, Q; Liao, Z; Li, G; Deng, J; Liu, L; Yu, Y; et al. MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB. JCI insight. 2020; 5.

Mukherjee, S; Chaturvedi, P; Rankin, SA; Fish, MB; Wlizla, M; Paraiso, KD; MacDonald, M; Chen, X; Weirauch, MT; Blitz, IL; et al. Sox17 and b-catenin co-occupy wntresponsive enhancers to govern the endoderm gene regulatory network. eLife. 2020; 9:1-26.

Ochayon, DE; Ali, A; Alarcon, PC; Krishnamurthy, D; Kottyan, LC; Borchers, MT; Waggoner, SN. IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells. Journal of Leukocyte Biology. 2020; 107:663-671.

Porollo, A; Cushion, MT. Advances in Genomics Research of Pneumocystis Species. Reference Module in Life Sciences. : Elsevier; Elsevier; 2020.

Qiu, R; Yu, X; Wang, L; Han, Z; Yao, C; Cui, Y; Hou, G; Dai, D; Jin, W; Shen, N. Inhibition of glycolysis in pathogenic TH17 cells through targeting a miR-21-Peli1-c-rel pathway prevents autoimmunity. Journal of immunology (Baltimore, Md. : 1950). 2020; 204:3160-3170.

Rajaram, S; Canaday, LM; Ochayon, DE; Rangel, KM; Ali, A; Gyurova, IE; Krishnamurthy, D; Fletcher, JS; Reighard, SD; Cox, A; et al. The Promise and Peril of Natural Killer Cell Therapies in Pulmonary Infection. Immunity. 2020; 52:887-889.

Reighard, SD; Cranert, SA; Rangel, KM; Ali, A; Gyurova, IE; de la Cruz-Lynch, AT; Tuazon, JA; Khodoun, MV; Kottyan, LC; Smith, DF; et al. Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells. 2020; 1:100003-100003.

Robinson, JR; Carroll, RJ; Bastarache, L; Chen, Q; Mou, Z; Wei, W; Connolly, JJ; Mentch, F; Sleiman, P; Crane, PK; et al. Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization. World Journal of Surgery. 2020; 44:84-94.

Rotenberg, D; Baumann, AA; Ben-Mahmoud, S; Christiaens, O; Dermauw, W; Ioannidis, P; Jacobs, CG C; Vargas Jentzsch, IM; Oliver, JE; Poelchau, MF; et al. Genome-enabled insights into the biology of thrips as crop pests. BMC Biology. 2020; 18.

Scott, MJ; Benoit, JB; Davis, RJ; Bailey, ST; Varga, V; Martinson, EO; Hickner, PV; Syed, Z; Cardoso, GA; Torres, TT; et al. Genomic analyses of a livestock pest, the New World screwworm, find potential targets for genetic control programs. Communications Biology. 2020; 3.

Sirvent, S; Vallejo, AF; Davies, J; Clayton, K; Wu, Z; Woo, J; Riddell, J; Chaudhri, VK; Stumpf, P; Nazlamova, LA; et al. Genomic programming of IRF4-expressing human Langerhans cells. Nature Communications. 2020; 11.

Sparks, ME; Bansal, R; Benoit, JB; Blackburn, MB; Chao, H; Chen, M; Cheng, S; Childers, C; Dinh, H; Doddapaneni, HV; et al. Brown marmorated stink bug, Halyomorpha halys (Stål), genome: Putative underpinnings of polyphagy, insecticide resistance potential and biology of a top worldwide pest. BMC Genomics. 2020; 21.

Stevens, ML; Zhang, Z; Johansson, E; Ray, S; Jagpal, A; Ruff, BP; Kothari, A; He, H; Martin, LJ; Ji, H; et al. Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk. Nature Communications. 2020; 11.

Stoll, ML; Duck, LW; Chang, MH; Colbert, RA; Nigrovic, PA; Thompson, SD; Elson, CO. Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. Clinical Immunology. 2020; 216:108463-108463.

Thomas, M; Sakoda, LC; Hoffmeister, M; Rosenthal, EA; Lee, JK; van Duijnhoven, FJ B; Platz, EA; Wu, AH; Dampier, CH; de la Chapelle, A; et al. Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk. The American Journal of Human Genetics. 2020; 107:432-444.

Van Camp, P; Haslam, DB; Porollo, A. Bioinformatics approaches to the understanding of molecular mechanisms in antimicrobial resistance. International Journal of Molecular Sciences. 2020; 21:1363-1363.

Van Camp, P; Haslam, DB; Porollo, A. Prediction of Antimicrobial Resistance in Gram-Negative Bacteria From Whole-Genome Sequencing Data. Frontiers in Microbiology. 2020; 11.

Waggoner, SN. Circadian Rhythms in Immunity. Current Allergy and Asthma Reports. 2020; 20.

Wang, L; Qiu, R; Zhang, Z; Han, Z; Yao, C; Hou, G; Dai, D; Jin, W; Tang, Y; Yu, X; et al. The MicroRNA miR-22 Represses Th17 Cell Pathogenicity by Targeting PTEN-Regulated Pathways. 2020; 4:308-318.

Wu, N; Cernysiov, V; Davidson, D; Song, H; Tang, J; Luo, S; Lu, Y; Qian, J; Gyurova, IE; Waggoner, SN; et al. Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation. Cell Reports. 2020; 30:1129-1140.e5.

Xu, X; Zhou, Y; Fu, B; Zhang, J; Dong, Z; Zhang, X; Shen, N; Sun, R; Tian, Z; Wei, H. PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020; 34:6479-6492.

Yang, J; Wang, R; Huang, L; Zhang, M; Niu, J; Bao, C; Shen, N; Dai, M; Guo, Q; Wang, Q; et al. Urine Metabolic Fingerprints Encode Subtypes of Kidney Diseases. Angewandte Chemie International Edition. 2020; 59:1703-1710.

Yukawa, M; Jagannathan, S; Vallabh, S; Kartashov, AV; Chen, X; Weirauch, MT; Barski, A. AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation. The Journal of Experimental Medicine. 2020; 217.

Zeng, QX; Deng, J; Shen, N. Pathogenesis of CD8+ T cells in dextran sulfate sodium-induced murine acute colitis. Shanghai jiao tong da xue xue bao. Yi xue ban. 2020; 40:286-293.

Zhang, J; Chen, C; Fu, H; Yu, J; Sun, Y; Huang, H; Tang, Y; Shen, N; Duan, Y. MicroRNA-125a-Loaded Polymeric Nanoparticles Alleviate Systemic Lupus Erythematosus by Restoring Effector/Regulatory T Cells Balance. ACS Nano. 2020; 14:4414-4429.

Zhou, Y; Fu, B; Xu, X; Zhang, J; Tong, X; Wang, Y; Dong, Z; Zhang, X; Shen, N; Zhai, Y; et al. PBX1 expression in uterine natural killer cells drives fetal growth. Science Translational Medicine. 2020; 12:eaax1798-eaax1798.