Publications

Caster, DJ; Korte, EA; Merchant, ML; Klein, JB; Barati, MT; Joglekar, A; Wilkey, DW; Coventry, S; Hata, J; Rovin, BH; et al. Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression. Journal of Clinical Medicine. 2021; 10.

Dey, D; Sciascia, S; Pons-Estel, GJ; Ding, H; Shen, N. Health Disparities in Rheumatic Diseases Understanding Global Challenges in Africa, Europe, Latin America, and Asia and Proposing Strategies for Improvement. Rheumatic Disease Clinics of North America. 2021; 47:119-132.

Her, YR; Wang, L; Chepelev, I; Manterola, M; Berkovits, B; Cui, K; Zhao, K; Wolgemuth, DJ. Genome-wide chromatin occupancy of BRDT and gene expression analysis suggest transcriptional partners and specific epigenetic landscapes that regulate gene expression during spermatogenesis. Molecular Reproduction and Development. 2021; 88:141-157.

Ho, JS Y; Mok, BW Y; Campisi, L; Jordan, T; Yildiz, S; Parameswaran, S; Wayman, JA; Gaudreault, NN; Meekins, DA; Indran, SV; et al. TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Cell. 2021.

Johansson, E; Martin, LJ; He, H; Chen, X; Weirauch, MT; Kroner, JW; Khurana Hershey, GK; Biagini, JM. Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity. Clinical and Experimental Allergy. 2021.

Kottyan, LC; Trimarchi, MP; Lu, X; Caldwell, JM; Maddox, A; Parameswaran, S; Lape, M; D'Mello, RJ; Bonfield, M; Ballaban, A; et al. Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes. Journal of Allergy and Clinical Immunology. 2021; 147:255-266.

López-Isac, E; Smith, SL; Marion, MC; Wood, A; Sudman, M; Yarwood, A; Shi, C; Gaddi, VP; Martin, P; Prahalad, S; et al. Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms. Annals of the Rheumatic Diseases. 2021.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

Miraldi, ER; Chen, X; Weirauch, MT. Deciphering cis-regulatory grammar with deep learning. Nature Genetics. 2021; 53:266-268.

Namjou, B; Stanaway, IB; Lingren, T; Mentch, FD; Benoit, B; Dikilitas, O; Niu, X; Shang, N; Shoemaker, AH; Carey, DJ; et al. Evaluation of the MC4R gene across eMERGE network identifies many unreported obesity-associated variants. International Journal of Obesity. 2021; 45:155-169.

Nigrovic, PA; Colbert, RA; Holers, VM; Ozen, S; Ruperto, N; Thompson, SD; Wedderburn, LR; Yeung, RS M; Martini, A. Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nature reviews. Rheumatology. 2021.

Oatman, N; Dasgupta, N; Arora, P; Choi, K; Gawali, MV; Gupta, N; Parameswaran, S; Salomone, J; Reisz, JA; Lawler, S; et al. Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Science advances. 2021; 7.

Ochayon, DE; Waggoner, SN. The Effect of Unconventional Cytokine Combinations on NK-Cell Responses to Viral Infection. Frontiers in Immunology. 2021; 12.

Qu, B; Jiang, X; Shen, N. Chapter 30 MicroRNA in systemic lupus erythematosus. Systemic Lupus Erythematosus. 2021.

Reighard, SD; Krishnamurthy, D; Cevik, H; Ochayon, DE; Ali, A; Seelamneni, H; Brunner, HI; Waggoner, SN. Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease. Cytotherapy. 2021; 23:37-45.

Santiago, IJ; Zhang, D; Saras, A; Pontillo, N; Xu, C; Chen, X; Weirauch, MT; Mistry, M; Ginty, DD; Pecot, MY; et al. Drosophila Fezf functions as a transcriptional repressor to direct layer-specific synaptic connectivity in the fly visual system. Proceedings of the National Academy of Sciences of the United States of America. 2021; 118.

Song, R; Gao, Y; Dozmorov, I; Malladi, V; Saha, I; McDaniel, MM; Parameswaran, S; Liang, C; Arana, C; Zhang, B; et al. IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility. Cell Reports. 2021; 34.

Stone, HK; Parameswaran, S; Eapen, AA; Chen, X; Harley, JB; Devarajan, P; Weirauch, MT; Kottyan, L. Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk. Kidney International Reports. 2021; 6:187-195.

Suri, P; Stanaway, IB; Zhang, Y; Freidin, MB; Tsepilov, YA; Carrell, DS; Williams, FM K; Aulchenko, YS; Hakonarson, H; Namjou, B; et al. Genome-wide association studies of low back pain and lumbar spinal disorders using electronic health record data identify a locus associated with lumbar spinal stenosis. Pain. 2021.

Thomas, M; Sakoda, LC; Hoffmeister, M; Rosenthal, EA; Lee, JK; van Duijnhoven, FJ B; Platz, EA; Wu, AH; Dampier, CH; de la Chapelle, A; et al. Response to Li and Hopper. American Journal of Human Genetics. 2021; 108:527-529.

Xu, N; Zhou, T; Hou, GJ; Shen, N; Tang, YJ. Application of CRISPR/Cas9-mediated homologous recombination to the functional study of disease-associated genetic variants located in non-coding region. Journal of Shanghai Jiaotong University (Medical Science). 2021; 41:8-15.

Zhu, T; Zhang, X; Chen, X; Brown, A; Weirauch, M; Guilbert, T; Hershey, GK; Myers, JB. (1) DNA methylation biomarkers in nasal epithelium for severe asthma in children. Journal of Allergy and Clinical Immunology. 2021; 147.