Center for Autoimmune Genomics and Etiology (CAGE)

The Center for Autoimmune Genomics and Etiology can facilitate high-throughput custom SNP and whole-genome genotyping on the Illumina platform using the sophisticated iScan System.

• For additional information or to arrange for services, please contact Sara Lazaro (sara.lazaro@cchmc.org; 513-803-3309).
• To submit samples for processing, please fill out a Service Request Form and email to Sara Lazaro.

In collaboration with the Division of Human Genetics and using trio analysis (affected child and non-affected parents), the Center for Autoimmune Genomics and Etiology can identify de novo, rare recessive and compound heterozygote variants in the exomes of children with no family history of a particular disease.

Alternatively, we also offer whole genome sequencing analysis and non-human (microbiome, metagenomics) sequencing analysis to identify the microbial communities in human specimens.

• For additional information or to arrange for services, please contact Sara Lazaro (sara.lazaro@cchmc.org; 513-803-3309).
• To submit samples for processing, please fill out a Service Request Form and email to Sara Lazaro. 
• Clinical processing of samples also requires this Clinical Next Generation Sequencing Submission Form to be completed and emailed to Sara Lazaro or faxed to 513-803-5246. 

The Center for Autoimmune Genomics and Etiology provides genetically defined samples to collaborators from people with and without lupus.

For additional information, please contact 

• Carrie Weaver (carrie.weaver@cchmc.org; 513-803-3307), 
• Sara Lazaro (sara.lazaro@cchmc.org; 513-803-3309), or
• John Harley (john.harley@cchmc.org; 513-803-3665).