Epilepsy Research

According to the national average, it takes 10 years to be referred to an epilepsy surgical clinic. At Cincinnati Children’s it takes an average of 6 years. While we are better than the national average, we know we can do better.

Our lab is working on using the latest advances in artificial intelligence to decrease the time for surgical referral to just 3 years.

Research Studies

(click title to read more)     
Childhood Absence Epilepsy (CAE)   Identification of the optimal anticonvulsant for initial treatment of Childhood Absence Epilepsy.
Comprehensive Epilepsy Center (CEC)   Summarization of patient information for clinicians through machine-learning algorithms.
Epilepsy Surgery System (ESS)   Development of a technology that will use epilepsy free-text progress notes to extract information to be fed into a decision support tool.
pediatric Status Epilepticus Research Group (pSERG)  Refractory Status Epilepticus (RSE) registry that will enable us to determine the most effective treatment and monitoring algorithms by establishing a cohort of well-identified RSE patients to identify biomarkers of outcome.
Multi-Institutional Pediatric Decision Support System (MiPEDS)  Automatic collection of epilepsy measurement indicators to be anonymized for cross-institutional comparisons.
I2B2 Data Warehouse and Natural Language Processing  Data warehouse modeled on the star schema structure. It contains fact tables to house facts about patients.
Children's Hospital Resource In Selecting Therapy Individualized Expert (CHRISTINE)  Application which provides decision support for epilepsy patient drug selection/common web application framework for all applications built by the Pestian Lab.