In the News
News, research, events, and commentary from the biomedical informatics team at Cincinnati Children's Hospital Medical Center and the University of Cincinnati.
Cincinnati Children’s and the University of Cincinnati have joined together to launch the first genomics conference in the Midwest region. Precision Genomics Midwest will be held Friday, May 19 at the Kingsgate Marriott Conference Center. The conference focuses on genomic research, clinical translation, and ethics.
A project designed to use iPads to help children who are deaf or hard of hearing improve their language skills was recently featured in a news report on local station WKRC Cincinnati 12. A research IT team in the Division of Biomedical Informatics supports the technology used in this important study.
The International Medical Informatics Association (IMIA) has named two papers by Yizhao Ni, PhD, and his colleagues as among the five best natural language processing (NLP) papers of 2015. Both papers are featured in the IMIA Yearbook of Medical Informatics 2016, and have received other accolades as well.
Three new faculty members recently joined the biomedical informatics team at the University of Cincinnati and Cincinnati Children’s: Kevin Dufendach, MD, Emily Miraldi, PhD, and Danny T. Y. Wu, PhD.
Researchers at Cincinnati Children’s have created a software application and clinical system called NINJA that taps into the power of electronic medical records to protect hospitalized children from a potentially serious safety threat – acute kidney injury (AKI).
Scientists have harnessed the power of genomic big data and animal models of to identify the underlying causes and potential new treatments for idiopathic pulmonary fibrosis (IPF), a lung disease that kills an estimated 40,000 people annually in the United States.
The strength of the rich IT environment at Cincinnati Children’s and its accomplishments in adopting electronic medical records for use in improving patient care were recognized at a February event during the annual conference of the Healthcare Information and Management Systems Society (HIMSS) held in Orlando, FL.
In recognition of his excellence over the last nine years at transforming the research computing environment at Cincinnati Children’s, Michal Kouril, PhD, an assistant professor in the Division of Biomedical Informatics, has won the Service Achievement Award from the Cincinnati Children’s Research Foundation for 2017.
The 2016 Research Annual Report of the Cincinnati Children’s Research Foundation published in January celebrates the outstanding research contributions of its 951 faculty across 52 research divisions or centers. In its 168 pages, the report details facts and figures highlighting Cincinnati Children’s accomplishments as a powerhouse in the world of pediatric research.
A new open source software package called uQIust that enables protein and RNA structure prediction, molecular simulations, and retrieval and analysis of structural data is now available to investigators. It offers a versatile, efficient, and easy-to-use toolkit for macromolecular structure exploration and analysis, supporting ultrafast clustering and model quality assessment.
“Marker Genes” Reveal Deadly Secrets of Idiopathic Pulmonary Fibrosis
Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF).
Several faculty members within the Division of Biomedical Informatics have joined forces to publish the second edition of the popular textbook, Pediatric Biomedical Informatics: Computer Applications in Pediatric Research (Springer, 2016)
As recently as two years ago, women represented only 6% of computer and information sciences students at the University of Cincinnati (UC). Surbhi Bhatnagar, a PhD student at UC studying computer science and engineering with a bioinformatics focus, is working hard with local student and community groups to help change that.
A new study by John Pestian, PhD shows that computer technology known as machine learning is up to 93 percent accurate in correctly classifying a suicidal person and 85 percent accurate in identifying a person who is suicidal, has a mental illness but is not suicidal, or neither. These results provide strong evidence for using advanced technology as a decision-support tool to help clinicians and caregivers identify and prevent suicidal behavior.
The Agency for Healthcare Research and Quality has awarded a team of Cincinnati Children’s researchers a grant to implement natural language processing (NLP) to help in early identification and referral of children who are potential candidates for epilepsy neurosurgery. This project is one of the first in the field to study the integration of NLP recommendations into clinical care.
The U.S. Department of Health and Human Services’ Office of the National Coordinator for Health Information Technology (ONC) has awarded Keith Marsolo, PhD, a Standards Exploration Grant to study the cost efficiencies of integrating clinical research systems within a medical center’s electronic health record (EHR).
With the goal of encouraging collaborations between molecular and computational biologists, chemists and biophysicists, the Division of Biomedical Informatics at Cincinnati Children’s is launching a new focus group on biomolecular informatics.
Nick Pratap, MB, BChir, of Cincinnati Children’s Department of Anesthesia and the Heart Institute and Yizhao Ni, PhD, of the Division of Biomedical Informatics have received a $300,000, two-year grant from the Agency for Healthcare Research and Quality that aims to use electronic health records (EHRs) to identify children likely to suffer last-minute surgery cancellation.
As an avalanche of data and the increasing sophistication of technology change the way biomedical research is conducted, data scientists are an essential part of the research team. Biomedical informatics experts are in high demand for their ability to dive deeply into clinical, molecular and genomic data.
The biomedical informatics graduate program at UC and Cincinnati Children’s is working to meet that demand with PhD program and a 7-course graduate certificate.
Developing blood cells are caught in tugs of war between competing gene regulatory networks before finally deciding what type of cell to become, according to a study published Aug. 31 in Nature. In the study, authors Harinder Singh, PhD and H. Leighton Grimes, PhD blended laboratory biology with a new bioinformatics computer program (ICGS) developed at Cincinnati Children’s with study co-author Nathan Salomonis, PhD, Division of Biomedical Informatics. ICGS (Iterative Clustering and Guide-Gene Selection) gives researchers a comprehensive view of the overwhelming amount of data generated by single-cell RNA sequencing.
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