Publications

Walsh, KB; Zhang, X; Zhu, X; Wohleb, E; Woo, D; Lu, L; Adeoye, O. Intracerebral hemorrhage induces monocyte-related gene expression within six hours: Global transcriptional profiling in swine ICH. Metabolic Brain Disease. 2019; 34:763-774.

Helbig, I; Lopez-Hernandez, T; Shor, O; Galer, P; Ganesan, S; Pendziwiat, M; Rademacher, A; Ellis, CA; Hümpfer, N; Schwarz, N; et al. A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy. The American Journal of Human Genetics. 2019; 104:1060-1072.

Panmanee, W; Su, S; Schurr, MJ; Lau, GW; Zhu, X; Ren, Z; McDaniel, CT; Lu, LJ; Ohman, DE; Muruve, DA; et al. The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a Delta mucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection. PLoS ONE. 2019; 14.

Li, T; Fang, Z; Peng, H; Zhou, J; Liu, P; Wang, Y; Zhu, W; Zhang, Q; Chen, L; Li, L; et al. Application of high-throughput amplicon sequencing-based SSR genotyping in genetic background screening. BMC Genomics. 2019; 20.

Hulin, A; Hortells, L; Gomez-Stallons, MV; O'Donnell, A; Chetal, K; Adam, M; Lancellotti, P; Oury, C; Potter, SS; Salomonis, N; et al. Maturation of heart valve cell populations during postnatal remodeling. Development (Cambridge). 2019; 146.

Kurowski, BG; Treble-Barna, A; Pilipenko, V; Wade, SL; Yeates, KO; Taylor, HG; Martin, LJ; Jegga, AG. Genetic Influences on Behavioral Outcomes After Childhood TBI: A Novel Systems Biology-Informed Approach. Frontiers in Genetics. 2019; 10.

Kirkendall, ES; Ni, Y; Lingren, T; Leonard, M; Hall, ES; Melton, K. Data Challenges With Real-Time Safety Event Detection And Clinical Decision Support. Journal of Medical Internet Research. 2019; 21.

Kozlovski, T; Mitelpunkt, A; Thaler, A; Gurevich, T; Orr-Urtreger, A; Gana-Weisz, M; Shachar, N; Galili, T; Marcus-Kalish, M; Bressman, S; et al. Hierarchical data-driven analysis of clinical symptoms among patients with Parkinson's disease. Frontiers in Neurology. 2019; 10:1-7.

Kasam, RK; Reddy, GB; Jegga, AG; Madala, SK. Dysregulation of Mesenchymal Cell Survival Pathways in Severe Fibrotic Lung Disease: The Effect of Nintedanib Therapy. Frontiers in Pharmacology. 2019; 10.

Nasimuzzaman, M; Arumugam, PI; Mullins, ES; James, JM; Vanden Heuvel, K; Narciso, MG; Shaw, MA; McGraw, S; Aronow, BJ; Malik, P. Elimination of the fibrinogen integrin aMb2-binding motif improves renal pathology in mice with sickle cell anemia. Blood Advances. 2019; 3:1519-1532.

Weng, Q; Wang, J; Wang, J; He, D; Cheng, Z; Zhang, F; Verma, R; Xu, L; Dong, X; Liao, Y; et al. Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Cell Stem Cell. 2019; 24:707-723.e8.

Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Journal of Clinical Investigation. 2019; 129:2014-2028.

Hagedorn, PA; Kirkendall, ES; Spooner, SA; Mohan, V. Inpatient Communication Networks: Leveraging Secure Text-Messaging Platforms to Gain Insight into Inpatient Communication Systems. Applied Clinical Informatics. 2019; 10:471-478.

Smith, MA; Choudhary, GS; Pellagatti, A; Choi, K; Bolanos, LC; Bhagat, TD; Gordon-Mitchell, S; Von Ahrens, D; Pradhan, K; Steeples, V; et al. U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies. Nature Cell Biology. 2019; 21:640-650.

Peters, AL; Luo, Z; Li, J; Mourya, R; Wang, Y; Dexheimer, P; Shivakumar, P; Aronow, B; Bezerra, JA. Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion. PLoS ONE. 2019; 14.

Stemmer, A; Galili, T; Kozlovski, T; Zeevi, Y; Marcus-Kalish, M; Benjamini, Y; Mitelpunkt, A. Current and Potential Approaches for Defining Disease Signatures: a Systematic Review. Journal of Molecular Neuroscience. 2019; 67:550-558.

Pogacar, R; Carpenter, TP; Shenk, CE; Kouril, M. Tools and methods for measuring implicit consumer cognition. Handbook of Research Methods in Consumer Psychology. 2019.

Dwivedi, P; Muench, DE; Wagner, M; Azam, M; Grimes, HL; Greis, KD. Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors. Scientific Data. 2019; 6.

Taylor, DM; Aronow, BJ; Tan, K; Bernt, K; Salomonis, N; Greene, CS; Frolova, A; Henrickson, SE; Wells, A; Pei, L; et al. The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell. 2019; 49:10-29.

Percy, Z; DeFranco, E; Xu, F; Hall, ES; Haynes, EN; Jones, D; Muglia, LJ; Chen, A. Trimester specific PM2.5 exposure and fetal growth in Ohio, 2007-2010. Environmental Research. 2019; 171:111-118.

Denson, LA; Jurickova, I; Karns, R; Shaw, KA; Cutler, DJ; Okou, D; Valencia, CA; Dodd, A; Mondal, K; Aronow, BJ; et al. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 2019; 25:547-560.

Haberman, Y; Schirmer, M; Dexheimer, PJ; Karns, R; Braun, T; Kim, M; Walters, TD; Baldassano, RN; Noe, JD; Rosh, J; et al. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunology. 2019; 12:491-502.

Rossi, RM; Hall, E; Defranco, EA. Contemporary trends in cesarean delivery utilization for live births between 22 0/7 and 23 6/7 weeks of gestation. Obstetrics and Gynecology. 2019; 133:451-458.

Nielsen, SC A; Roskin, KM; Jackson, KJ L; Joshi, SA; Nejad, P; Lee, J; Wagar, LE; Pham, TD; Hoh, RA; Nguyen, KD; et al. Shaping of infant B cell receptor repertoires by environmental factors and infectious disease. Science Translational Medicine. 2019; 11.

Yonekura, A; Kawanaka, H; Prasath, VB S; Aronow, BJ; Tsuruoka, S; IEEE, . (2019) Glioma Subtypes Clustering Method using Histopathological Image Analysis. IEEE. 442-446.

Fletcher, JS; Wu, J; Jessen, WJ; Pundavela, J; Miller, JA; Dombi, E; Kim, M; Rizvi, TA; Chetal, K; Salomonis, N; et al. Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice. JCI insight. 2019; 4.

Shaw, KA; Cutler, DJ; Okou, D; Dodd, A; Aronow, BJ; Haberman, Y; Stevens, C; Walters, TD; Griffiths, A; Baldassano, RN; et al. Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and Immunity. 2019; 20:131-142.

Turnier, JL; Brunner, HI; Bennett, M; Aleed, A; Gulati, G; Haffey, WD; Thornton, S; Wagner, M; Devarajan, P; Witte, D; et al. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology. 2019; 58:321-330.

Ljungberg, MC; Sadi, M; Wang, Y; Aronow, BJ; Xu, Y; Kao, RJ; Liu, Y; Gaddis, N; Ardini-Poleske, ME; Umrod, T; et al. Spatial distribution of marker gene activity in the mouse lung during alveolarization. Data in Brief. 2019; 22:365-372.

Chen, J; Xu, H; Jegga, A; Zhang, K; White, PS; Zhang, G. Novel phenotype-disease matching tool for rare genetic diseases. Genetics in Medicine. 2019; 88:341-348.

Hall, ES; McAllister, JM; Wexelblatt, SL. Developmental Disorders and Medical Complications Among Infants with Subclinical Intrauterine Opioid Exposures. Population Health Management. 2019; 22:19-24.

Brokamp, C; Beck, AF; Goyal, NK; Ryan, P; Greenberg, JM; Hall, ES. Material community deprivation and hospital utilization during the first year of life: an urban population-based cohort study. Annals of Epidemiology. 2019; 30:37-43.

Dorn, LE; Lasman, L; Chen, J; Xu, X; Hund, TJ; Medvedovic, M; Hanna, JH; van Berlo, JH; Accornero, F. The N-6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy. Circulation. 2019; 139:533-545.

Haberman, Y; Karns, R; Dexheimer, PJ; Schirmer, M; Somekh, J; Jurickova, I; Braun, T; Novak, E; Bauman, L; Collins, MH; et al. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nature Communications. 2019; 10.

Lewis, CS; Thomas, HE; Orr-Asman, MA; Green, LC; Boody, RE; Matiash, K; Karve, A; Hisada, YM; Davis, HW; Qi, X; et al. mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors. Journal of Thrombosis and Haemostasis. 2019; 17:169-182.

Higashi, AY; Aronow, BJ; Dressler, GR. Expression Profiling of Fibroblasts in Chronic and Acute Disease Models Reveals Novel Pathways in Kidney Fibrosis. Journal of the American Society of Nephrology : JASN. 2019; 30:80-94.

Ramsey, LB; Prows, CA; Zhang, K; Saldana, SN; Sorter, MT; Pestian, JP; Wenstrup, RJ; Vinks, AA; Glauser, TA. Implementation of Pharmacogenetics at Cincinnati Children's Hospital Medical Center: Lessons Learned Over 14 Years of Personalizing Medicine. Clinical Pharmacology and Therapeutics. 2019; 105:49-52.

Szczesniak, RD; Brokamp, C; Su, W; Mcphail, GL; Pestian, J; Clancy, JP. Improving Detection of Rapid Cystic Fibrosis Disease Progression-Early Translation of a Predictive Algorithm Into a Point-of-Care Tool. IEEE Journal of Translational Engineering in Health and Medicine-JTEHM. 2019; 7.

Wang, Y; Yella, J; Jegga, AG. Transcriptomic Data Mining and Repurposing for Computational Drug Discovery. Methods in molecular biology (Clifton, N.J.). 2019; 1903:73-95.

Dwivedi, P; Muench, DE; Wagner, M; Azam, M; Grimes, HL; Greis, KD. Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. Leukemia. 2019; 33:75-87.

Yang, J; Kalim, KW; Li, Y; Duan, X; Nguyen, P; Hershey, GK K; Kroner, J; Ruff, B; Zhang, L; Salomonis, N; et al. Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation. Clinical and Experimental Allergy. 2019; 49:92-107.

Salomonis, N. Investigating cell fate decisions with ICGS analysis of single cells. Methods in molecular biology (Clifton, N.J.). 2019; 1975:251-275.