The Powers Lab is focused on clinical trials and translational research that leads to an evidence-base that changes clinical practice. Interventions include both medication treatments and bio-behavioral therapies. Current studies involve a large, nation-wide trial testing the efficacy of two medications used for migraine prevention in children and adolescents; a trial testing a combination of medication and cognitive behavioral therapy for youth with chronic migraine; and studies of behavioral treatments aimed at improving dietary adherence in young children with chronic illnesses such as cystic fibrosis and obesity.