A photo of Andrew D. Hershey.

Andrew D. Hershey, MD, PhD, FAHS


  • Endowed Chair and Director, Division of Neurology
  • Headache Medicine Specialist, Division of Neurology
  • Professor, UC Department of Pediatrics
Cincinnati Children's Headache Center is an international leader in the treatment, education and research of headaches in children, adolescents and young adults. Our goal is not only to provide the best possible care to our patients but also to help children around the world through our research and education.

About

Biography

As a pediatric neurologist and headache medicine specialist, I combine my clinical interests with my research interests. My clinical interests lie in improving the outcomes for children, adolescents and young adults with headaches, most of which are migraine. My research seeks to understand the clinical and biological characteristics of headaches in order to improve the outcomes of not only the patients and families we see, but of patients everywhere.

My PhD focused on the molecular biology of the Substance P receptor, a neuromodulator of pain pathways. My residency training was in neurology with a special emphasis on child neurology. Combining these two interests naturally led to the study of migraine in children, adolescents and young adults. My career was guided by several mentors along the way, with two of the foremost being Dr. James Krause, my PhD mentor, and Dr. Arthur Prensky, a founder of child neurology who had an interest in headaches.

At Cincinnati Children’s Headache Center, we use a multidisciplinary team approach that incorporates neurology, psychology and nursing to improve the outcomes of these children, adolescents and young adults. A foundation of this approach is a consistent goal of educating the patients on how to manage their disease. Our responsibility is to answer all their questions through a combination of research and education.

We are the only pediatric center in the United States to be recognized as an Advanstar Clinical Center of Excellence in Headache Medicine by Medical Economics. I have received the Seymour Solomon Award from the American Headache Society. I am on multiple national and international committees that have established the treatment and research guidelines for headache medicine.

Cincinnati Children's Headache Center was one of the five founding institutions for the United Council for Neurologic Subspecialties (UCNS)-certified headache medicine training and the only one of the five dedicated to children and adolescents. Our program has been funded consistently by the National Institutes of Health (NIH) since 2003, with our largest grant being $18 million for the Childhood and Adolescent Migraine prevention (CHAMP) study, as reported in New England Journal of Medicine.

Cincinnati Children's Headache Center is an international leader in the treatment, education and research of headaches in children, adolescents and young adults. Our goal is not only to provide the best possible care to our patients but also to help children around the world through our research and education.

Migraine is a genetic condition, but multiple genes contribute to the disease. This results in variable symptoms and risk factors. In our research, we are seeking better disease characterization and learning from our patients, which will help us tease apart these factors. We hope to ultimately improve the lives of our patients and families.

When I’m not helping patients or engaged in research, I like to be out in nature with my family. We enjoy walking, kayaking, hiking and golfing.

Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

View Insurance Information

Publications

Selected

CGRP - The Next Frontier for Migraine. Hershey, AD. New England Journal of Medicine. 2017; 377:2190-2191.

Selected

Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine. Powers, SW; Coffey, CS; Chamberlin, LA; Ecklund, DJ; Klingner, EA; Yankey, JW; Korbee, LL; Porter, LL; Hershey, AD; Investigators, CH A M P. New England Journal of Medicine. 2017; 376:115-124.

The spectrum of indomethacin-responsive headaches in children and adolescents. Myers, KA; Barmherzig, R; Raj, NR; Berrahmoune, S; Ingelmo, P; Saint-Martin, C; Khan, AQ; Kouri, M; Morris, C; Hershey, AD; et al. Cephalalgia. 2022; 42:793-797.

New insight into the neural mechanisms of migraine in adolescents: Relationships with sleep. Nahman-Averbuch, H; Schneider, VJ; Lee, GR; Peugh, JL; Hershey, AD; Powers, SW; de Zambotti, M; Coghill, RC; King, CD. Headache. 2022; 62:668-680.

Multimodal Assessment of Medication Adherence Among Youth With Migraine: An Ancillary Study of the CHAMP Trial. Reidy, BL; Powers, SW; Coffey, CS; Chamberlin, LA; Ecklund, DJ; Klingner, EA; Yankey, JW; Korbee, LL; Porter, LL; Peugh, J; et al. Journal of Pediatric Psychology. 2022; 47:376-387.

Comparison of Remote Electrical Neuromodulation and Standard-Care Medications for Acute Treatment of Migraine in Adolescents: A Post Hoc Analysis. Hershey, AD; Irwin, S; Rabany, L; Gruper, Y; Ironi, A; Harris, D; Sharon, R; McVige, J. Pain Medicine. 2022; 23:815-820.

Board Walk. Hershey, A. Cephalalgia. 2022; 42.

Nummular headache in children: A case series and systematic literature review. Lax, DN; Hershey, AD; Kabbouche, MA; Kacperski, J. 2022; 5.

Predictors of Improvement in Pediatric Chronic Migraine: Results from the Cognitive-Behavioral Therapy and Amitriptyline Trial. Rettig, EK; Ergun, G; Warfield, JR; Slater, SK; LeCates, SL; Kabbouche, MA; Kacperski, J; Hershey, AD; Powers, SW. Journal of Clinical Psychology in Medical Settings. 2022; 29:113-119.

Trajectory of treatment response in the child and adolescent migraine prevention (CHAMP) study: A randomized clinical trial. Reidy, BL; Peugh, J; Hershey, AD; Coffey, CS; Chamberlin, LA; Ecklund, DJ; Klingner, EA; Yankey, JW; Korbee, LL; Porter, LL; et al. Cephalalgia. 2022; 42:44-52.

From the Blog


Research Reinforces Alternatives to Medication in Migraine Care
Mind Brain Behavior

Research Reinforces Alternatives to Medication in Migraine Care

Andrew D. Hershey, MD, PhD, FAHS, Scott W. Powers, PhD, ABPP, FAHS7/27/2021

Research from Cincinnati Children’s Leads to New Migraine Treatment Guidelines
Mind Brain Behavior

Research from Cincinnati Children’s Leads to New Migraine Treatment Guidelines

Andrew D. Hershey, MD, PhD, FAHS8/22/2019

CHAMP Study Challenges Medication-Driven Approach to Migraine Care
Mind Brain Behavior

CHAMP Study Challenges Medication-Driven Approach to Migraine Care

Andrew D. Hershey, MD, PhD, FAHS6/30/2019

Patient Ratings and Comments

All patient satisfaction ratings and comments are submitted by actual patients and verified by a leading independent patient satisfaction company, NRC Health. Patient identities are withheld to ensure confidentiality and privacy. Only those providers whose satisfaction surveys are administered through Cincinnati Children’s Hospital Medical Center are displayed. Click here to learn more about our survey