Critical Care

Critical Care


Aydin, E; Joshi, R; Oria, M; Lim, FY; Varisco, BM; Peiro, JL. Transuterine Fetal Tracheal Occlusion Model in Mice. Journal of Visualized Experiments. 2021.

Banerjee, S; Mohammed, A; Wong, HR; Palaniyar, N; Kamaleswaran, R. Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission. Frontiers in Immunology. 2021; 12.

Benscoter, A; Brilli, R; Wheeler, D; Stalets, E. Healthcare-Associated Infections. In: Zimmerman J; Rotta A, Ed. Fuhrman and Zimmerman's Pediatric Critical Care. Philadelphia, PA: Elsevier; 2021.

Bridges, BC; Kilbaugh, TJ; Barbaro, RP; Bembea, MM; Chima, RS; Potera, RM; Rosner, EA; Sandhu, HS; Slaven, JE; Tarquinio, KM; et al. Veno-Venous Extracorporeal Membrane Oxygenation for Children With Cancer or Hematopoietic Cell Transplant: A Ten Center Cohort. ASAIO Journal. 2021; 67:923-929.

Dandoy, CE; Rotz, S; Alonso, PB; Klunk, A; Desmond, C; Huber, J; Ingraham, H; Higham, C; Dvorak, CC; Duncan, C; et al. A pragmatic multi-institutional approach to understanding transplant-associated thrombotic microangiopathy after stem cell transplant. Blood Advances. 2021; 5:1-11.

Demerle, KM; Angus, DC; Baillie, JK; Brant, E; Calfee, CS; Carcillo, J; Chang, CC H; Dickson, R; Evans, I; Gordon, AC; et al. Sepsis Subclasses: A Framework for Development and Interpretation. Critical Care Medicine. 2021; 49:748-759.

Dewan, M; Parsons, A; Tegtmeyer, K; Wenger, J; Niles, D; Raymond, T; Cheng, A; Skellett, S; Roberts, J; Jani, P; et al. Contextual Factors Affecting Implementation of In-hospital Pediatric CPR Quality Improvement Interventions in a Resuscitation Collaborative. Pediatric Quality and Safety. 2021; 6.

Dewan, M; Soberano, B; Sosa, T; Zackoff, M; Hagedorn, P; Brady, PW; Chima, RS; Stalets, EL; Moore, L; Britto, M; et al. Assessment of a Situation Awareness Quality Improvement Intervention to Reduce Cardiac Arrests in the PICU. Pediatric Critical Care Medicine. 2021.

Dewan, M; Wolfe, H; Stalets, EL. Relentless Improvement: Overcoming the "Active Resisters and Organizational Constipators " to Drive Change. Pediatric Critical Care Medicine. 2021; 22:842-844.

Faustino, EV S; Shabanova, V; Raffini, LJ; Kandil, SB; Li, S; Pinto, MG; Cholette, JM; Hanson, SJ; Nellis, ME; Silva, CT; et al. Efficacy of Early Prophylaxis Against Catheter-Associated Thrombosis in Critically Ill Children: A Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine. 2021; 49:e235-e246.

Frazier, M; Dewan, M; Keller-Smith, R; Shoemaker, J; Stewart, C; Tegtmeyer, K. Improving CPR Quality by Using a Real-Time Feedback Defibrillator During Pediatric Simulation Training. Pediatric Emergency Care. 2021; Publish Ahead of Print.

Girdwood, ST; Kaplan, J; Vinks, AA. Methodologic Progress Note: Opportunistic Sampling for Pharmacology Studies in Hospitalized Children. Journal of hospital medicine (Online). 2021; 16:35-37.

Hasson, D; Goldstein, SL; Standage, SW. The application of omic technologies to research in sepsis-associated acute kidney injury. Pediatric Nephrology. 2021; 36:1075-1086.

Hayes, HV; Wolfe, V; O’connor, M; Levinsky, NC; Piraino, G; Zingarelli, B. Deficiency of AMPKα1 Exacerbates Intestinal Injury and Remote Acute Lung Injury in Mesenteric Ischemia and Reperfusion in Mice. International Journal of Molecular Sciences. 2021; 22.

Innis, K; Hasson, D; Bodilly, L; Sveen, W; Stalets, EL; Dewan, M. Do I Need Proof of the Culprit? Decreasing Respiratory Viral Testing in Critically Ill Patients. Hospital pediatrics. 2021; 11:e1-e5.

Kangelaris, KN; Clemens, R; Fang, X; Jauregui, A; Liu, T; Vessel, K; Deiss, T; Sinha, P; Leligdowicz, A; Liu, KD; et al. A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2021; 320:L892-L902.

Kassam, AF; Levinsky, NC; Mallela, JP; Angel, K; Opoka, A; Lahni, P; Sahay, RD; Fei, L; Nomellini, V; Wong, HR; et al. Olfactomedin 4-Positive Neutrophils Are Upregulated after Hemorrhagic Shock. American Journal of Respiratory Cell and Molecular Biology. 2021; 64:216-223.

Lautz, AJ; Wong, HR; Ryan, TD; Statile, CJ. Pediatric Sepsis Biomarker Risk Model Biomarkers and Estimation of Myocardial Dysfunction in Pediatric Septic Shock. Pediatric Critical Care Medicine. 2021.

Li, C; Davis, X; Lahni, P; Stuck, J; Williamson, L; Kaplan, J. Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning. American Journal of Physiology - Endocrinology and Metabolism. 2021; 321:E433-E442.

Mallory, PP; Barbaro, RP; Bembea, MM; Bridges, BC; Chima, RS; Kilbaugh, TJ; Potera, RM; Rosner, EA; Sandhu, HS; Slaven, JE; et al. Tracheostomy and long-term mechanical ventilation in children after veno-venous extracorporeal membrane oxygenation. Pediatric Pulmonology. 2021; 56:3005-3012.

Marsh, RA; Zoref-Lorenz, A; Owsley, E; Chaturvedi, V; Nguyen, TC; Goldman, JR; Henry, MM; Greenberg, JN; Ladisch, S; Hermiston, ML; et al. T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis. Blood. 2021; 137:2337-2346.

Maxwell, AR; Frazier, M; Varisco, BM. High-Frequency Jet Ventilation Is Making Slow Inroads to the Pediatric ICU. Respiratory Care. 2021; 66:349-350.

Meert, KL; Reeder, RW; Maddux, AB; Banks, R; Berg, RA; Newth, CJ; Hall, MW; Quasney, M; Carcillo, JA; McQuillen, PS; et al. Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities. Pediatric Critical Care Medicine. 2021; 22:e302-e313.

Niedbalski, PJ; Cochran, AS; Freeman, MS; Guo, J; Fugate, EM; Davis, CB; Dahlke, J; Quirk, JD; Varisco, BM; Woods, JC; et al. Validating in vivo hyperpolarized 129 Xe diffusion MRI and diffusion morphometry in the mouse lung. Magnetic Resonance in Medicine. 2021; 85:2160-2173.

Odum, JD; Wong, HR; Stanski, NL. A Precision Medicine Approach to Biomarker Utilization in Pediatric Sepsis-Associated Acute Kidney Injury. Frontiers in Pediatrics. 2021; 9.

Parsons, A; Unaka, NI; Stewart, C; Foster, J; Perez, V; Jones, NH Y; Kahn, R; Beck, AF; Riley, C. Seven practices for pursuing equity through learning health systems: Notes from the field. Learning Health Systems. 2021; 5.

Pfeiffer, S; Lauridsen, KG; Wenger, J; Hunt, EA; Haskell, S; Atkins, DL; Duval-Arnould, JM; Knight, LJ; Cheng, A; Gilfoyle, E; et al. Code Team Structure and Training in the Pediatric Resuscitation Quality International Collaborative. Pediatric Emergency Care. 2021; 37:e431-e435.

Pfeiffer, S; Wong, HR. Circulatory Failure/Shock. Pediatric Critical Care. 2021.

Pfeiffer, S; Zackoff, M; Bramble, K; Jacobs, L; Ruehlmann, K; Stalets, EL; Tegtmeyer, K; Dewan, M. Care Does Not Stop Following ROSC: A Quality Improvement Approach to Postcardiac Arrest Care. Pediatric Quality and Safety. 2021; 6.

Pilon, C. 2020 Virtual International Conference on Residency Education. Canadian Medical Education Journal. 2021; 12:e120-e179.

Pinto, NP; Berg, RA; Zuppa, AF; Newth, CJ; Pollack, MM; Meert, KL; Hall, MW; Quasney, M; Sapru, A; Carcillo, JA; et al. Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Frontiers in Pediatrics. 2021; 9.

Rahman, SA; Sullivan, JP; Barger, LK; St. Hilaire, MA; O'Brien, CS; Stone, KL; Phillips, AJ K; Klerman, EB; Qadri, S; Wright, KP; et al. Extended Work Shifts and Neurobehavioral Performance in Resident-Physicians. Pediatrics. 2021; 147.

Rumienczyk, I; Kulecka, M; Ostrowski, J; Mar, D; Bomsztyk, K; Standage, SW; Mikula, M. Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis. Journal of Inflammation Research. 2021; 14:2377-2388.

Senthil, K; Morgan, RW; Hefti, MM; Karlsson, M; Lautz, AJ; Mavroudis, CD; Ko, T; Nadkarni, VM; Ehinger, J; Berg, RA; et al. Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model. Resuscitation Plus. 2021; 6.

Standage, SW; Xu, S; Brown, L; Ma, Q; Koterba, A; Lahni, P; Devarajan, P; Kennedy, MA. NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. American Journal of Physiology - Renal Physiology. 2021; 320:F984-F1000.

Stanski, NL; Wong, HR; Basu, RK; Cvijanovich, NZ; Fitzgerald, JC; Weiss, SL; Bigham, MT; Jain, PN; Schwarz, A; Lutfi, R; et al. Recalibration of the Renal Angina Index for Pediatric Septic Shock. Kidney International Reports. 2021; 6:1858-1867.

Tang Girdwood, SC; Tang, PH; Murphy, ME; Chamberlain, AR; Benken, LA; Jones, RL; Stoneman, EM; Kaplan, JM; Vinks, AA. Demonstrating Feasibility of an Opportunistic Sampling Approach for Pharmacokinetic Studies of β-Lactam Antibiotics in Critically Ill Children. Journal of Clinical Pharmacology. 2021; 61:565-573.

Taylor, RJ; Ritter, DM; Frazier, ME; Zackoff, MW. Acute Ataxia and Paresthesia in a Healthy 5-year-old Girl. Pediatrics in Review. 2021; 42:329-331.

Tegtmeyer, K; Frazier, M; Dewan, M. Royale With Adrenalin: Intraosseous Versus IV Vascular Access for Out-of-Hospital Cardiac Arrest Resuscitation Epinephrine. Pediatric Critical Care Medicine. 2021; 22:332-334.

Wang, P; Mu, X; Zhao, H; Li, Y; Wang, L; Wolfe, V; Cui, SN; Wang, X; Peng, T; Zingarelli, B; et al. Administration of GDF3 Into Septic Mice Improves Survival via Enhancing LXRα-Mediated Macrophage Phagocytosis. Frontiers in Immunology. 2021; 12.

Wong, HR; Hart, KW; Lindsell, CJ; Sweeney, TE. External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients. Critical Care Medicine. 2021; 49:e98-e101.

Wong, HR; Reeder, RW; Banks, R; Berg, RA; Meert, KL; Hall, MW; McQuillen, PS; Mourani, PM; Chima, RS; Sorenson, S; et al. Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation. Pediatric Critical Care Medicine. 2021; 22:8-15.

Zackoff, MW; Cruse, B; Sahay, RD; Fei, L; Saupe, J; Schwartz, J; Klein, M; Geis, GL; Tegtmeyer, K. Development and Implementation of Augmented Reality Enhanced High-Fidelity Simulation for Recognition of Patient Decompensation. Simulation in Healthcare. 2021; 16:221-230.

Zackoff, MW; Young, D; Sahay, RD; Fei, L; Real, FJ; Guiot, A; Lehmann, C; Klein, M. Establishing Objective Measures of Clinical Competence in Undergraduate Medical Education Through Immersive Virtual Reality. Ambulatory Pediatrics. 2021; 21:575-579.

Zingarelli, B. First Do No Harm: A Proposal of an Expert-Guided Framework of Surrogate Humane Endpoints in Preclinical Models of Acute Lung Injury. Critical Care Medicine. 2021; 49:373-375.