Critical Care Medicine Research


Atreya, MR; Cvijanovich, NZ; Fitzgerald, JC; Weiss, SL; Bigham, MT; Jain, PN; Schwarz, AJ; Lutfi, R; Nowak, J; Allen, GL; et al. Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study. Critical Care (UK). 2022; 26:210.

Atreya, MR; Sanchez-Pinto, LN; Kamaleswaran, R. Commentary: 'Critical illness subclasses: all roads lead to Rome'. Critical Care (UK). 2022; 26:387.

Bell, MJ; Rosario, BL; Kochanek, PM; Adelson, PD; Morris, KP; Au, AK; Schober, M; Butt, W; Edwards, RJ; Zimmerman, J; et al. Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury. JAMA Network Open. 2022; 5:e2220969.

Caraballo, C; Mahajan, S; Valero-Elizondo, J; Massey, D; Lu, Y; Roy, B; Riley, C; Annapureddy, AR; Murugiah, K; Elumn, J; et al. Evaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018. JAMA Network Open. 2022; 5:e226385.

Caraballo, C; Ndumele, CD; Roy, B; Lu, Y; Riley, C; Herrin, J; Krumholz, HM. Trends in Racial and Ethnic Disparities in Barriers to Timely Medical Care Among Adults in the US, 1999 to 2018. JAMA Health Forum. 2022; 3:e223856.

Crosh, CC; Hutton, JS; Szumlas, GA; Xu, Y; Beck, AF; Riley, CL. Inequities in Public Library Branch Access and Children's Book Circulation in a Midwestern American City. The International Journal of Information, Diversity, & Inclusion. 2022; 6.

Dewan, M; Cooper, DS; Tegtmeyer, K. Low Inadequate Oxygen Delivery Index is Associated with Decreased Cardiac Arrest Risk in High-Risk Pediatric ICU Patients. Critical Care Explorations. 2022; 4:e0600.

Dewan, M; Soberano, B; Sosa, T; Zackoff, M; Hagedorn, P; Brady, PW; Chima, RS; Stalets, EL; Moore, L; Britto, M; et al. Assessment of a Situation Awareness Quality Improvement Intervention to Reduce Cardiac Arrests in the PICU. Pediatric Critical Care Medicine. 2022; 23:4-12.

Eisenberg, MA; Riggs, R; Paul, R; Balamuth, F; Richardson, T; DeSouza, HG; Abbadesa, MK; DeMartini, TK M; Frizzola, M; Lane, R; et al. Association Between the First-Hour Intravenous Fluid Volume and Mortality in Pediatric Septic Shock. Annals of Emergency Medicine. 2022; 80:213-224.

Fraiman, YS; Cheston, CC; Cabral, HJ; Allen, C; Asnes, AG; Barrett, JT; Batra, M; Bernstein, W; Bleeker, T; Dietz, PM; et al. Effect of a Novel Mindfulness Curriculum on Burnout During Pediatric Internship: A Cluster Randomized Clinical Trial. Obstetrical and Gynecological Survey. 2022; 77:561-563.

Fraiman, YS; Cheston, CC; Cabral, HJ; Allen, C; Asnes, AG; Barrett, JT; Batra, M; Bernstein, W; Bleeker, T; Dietz, PM; et al. Effect of a Novel Mindfulness Curriculum on Burnout During Pediatric Internship: A Cluster Randomized Clinical Trial. JAMA Pediatrics. 2022; 176:365-372.

Frazier, M; Dewan, M; Keller-Smith, R; Shoemaker, J; Stewart, C; Tegtmeyer, K. Improving CPR Quality by Using a Real-Time Feedback Defibrillator During Pediatric Simulation Training. Pediatric Emergency Care. 2022; 38:e993-e996.

Frazier, M; Dewan, M; Tegtmeyer, K. Who Let All These People In?. Hospital Pediatrics. 2022; 12:e129-e130.

Galiatsatos, P; Wilson, C; O'Brien, J; Gong, AJ; Angiolillo, D; Johnson, J; Myers, C; Strout, S; Mathai, S; Robinson, G; et al. A lack of race and ethnicity data in the treatment of hereditary hemorrhagic telangiectasia: a systematic review of intravenous bevacizumab efficacy. Orphanet Journal of Rare Diseases. 2022; 17:220.

Girdwood, ST; Dong, M; Tang, P; Stoneman, E; Jones, R; Yunger, T; Ostermeier, A; Curry, C; Forton, M; Hail, T; et al. Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment. Antimicrobial Agents and Chemotherapy. 2022; 66:e0142721.

Gist, KM; Fuhrman, D; Stanski, N; Menon, S; Soranno, DE. Subphenotypes of acute kidney injury in children. Current Opinion in Critical Care. 2022; 28:590-598.

Goldstein, SL; Akcan-Arikan, A; Alobaidi, R; Askenazi, DJ; Bagshaw, SM; Barhight, M; Barreto, E; Bayrakci, B; Bignall, ON R; Bjornstad, E; et al. Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement. JAMA Network Open. 2022; 5:e2229442.

Goldstein, SL; Krallman, KA; Kirby, C; Roy, JP; Collins, M; Fox, K; Schmerge, A; Wilder, S; Gerhardt, B; Chima, R; et al. Integration of the Renal Angina Index and Urine Neutrophil Gelatinase-Associated Lipocalin Improves Severe Acute Kidney Injury Prediction in Critically Ill Children and Young Adults. Kidney International Reports. 2022; 7:1842-1849.

Hasson, DC; Krallman, K; VanDenHeuvel, K; Menon, S; Piraino, G; Devarajan, P; Goldstein, SL; Alder, M. Olfactomedin 4 as a novel loop of Henle-specific acute kidney injury biomarker. Physiological Reports. 2022; 10:e15453.

Hasson, DC; Watanabe-Chailland, M; Romick-Rosendale, L; Koterba, A; Miner, DS; Lahni, P; Ma, Q; Goldstein, SL; Devarajan, P; Standage, SW. Choline supplementation attenuates experimental sepsis-associated acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2022; 323:F255-F271.

Jani, P; Sweberg, T; Dewan, M; Tegtmeyer, K; Mullan, P; Griffis, H; Zhang, X; Niles, D; Nadkarni, VM; Wolfe, H. Abstract 180: Impact Of Hot Debriefing Programs On Pediatric Cardiopulmonary Resuscitation Quality And Outcomes. Circulation. 2022; 146:a180.

Joshi, R; Batie, MR; Fan, Q; Varisco, BM. Mouse lung organoid responses to reduced, increased, and cyclic stretch. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2022; 322:L162-L173.

Kienzle, MF; Morgan, RW; Dewan, M; Hebbar, KB; Nadkarni, VM; Srinivasan, V; Tegtmeyer, K; Sutton, RM; Wolfe, HA. Weight-Based Versus Flat Dosing of Epinephrine During Cardiac Arrest in the PICU: A Multicenter Survey. Pediatric Critical Care Medicine. 2022; 23:e451-e455.

Kochanek, PM; Adelson, PD; Rosario, BL; Hutchison, J; Miller Ferguson, N; Ferrazzano, P; O'Brien, N; Beca, J; Sarnaik, A; LaRovere, K; et al. Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury. JAMA Network Open. 2022; 5:e220891.

Lauridsen, KG; Lasa, JJ; Raymond, TT; Yu, P; Niles, D; Sutton, RM; Morgan, RW; Fran Hazinski, M; Griffis, H; Hanna, R; et al. Association of chest compression pause duration prior to E-CPR cannulation with cardiac arrest survival outcomes. Resuscitation. 2022; 177:85-92.

Lautz, AJ; Wong, HR; Ryan, TD; Statile, CJ. Pediatric Sepsis Biomarker Risk Model Biomarkers and Estimation of Myocardial Dysfunction in Pediatric Septic Shock. Pediatric Critical Care Medicine. 2022; 23:e20-e28.

Loeb, D; Spear, C; Hayes, D. Encephalopathy in a Recent Lung Transplant Recipient. Chest. 2022; 161:e149-e152.

Maholtz, DE; Riley, CL. Screening for Social Needs in Critically Ill Patients: Addressing More Than Health Conditions. Pediatric Critical Care Medicine. 2022; 23:e541-e542.

Merritt, C; Glisson, M; Dewan, M; Klein, M; Zackoff, M. Implementation and Evaluation of an Artificial Intelligence Driven Simulation to Improve Resident Communication With Primary Care Providers. Academic Pediatrics. 2022; 22:503-505.

Myers, C; Stockwell, DC. The High Cost of Harm. Mayo Clinic Proceedings. 2022; 97:205-207.

Odum, JD; Standage, S; Alder, M; Zingarelli, B; Devarajan, P; Wong, HR. Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies. Shock. 2022; 57:687-693.

Pei, F; Yao, RQ; Ren, C; Bahrami, S; Billiar, TR; Chaudry, IH; Chen, DC; Chen, XL; Cui, N; Fang, XM; et al. Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression. Military Medical Research. 2022; 9:74.

Riley, C; Herrin, J; Lam, V; Parsons, AA; Kaplan, GA; Liu, D; Witters, D; Krumholz, HM; Roy, B. Trends and Variation in the Gap Between Current and Anticipated Life Satisfaction in the United States, 2008-2020. American Journal of Public Health. 2022; 112:509-517.

Riley, C; Roy, B. Riley and Roy Respond. American Journal of Public Health. 2022; 112:e2-e3.

Rosner, EA; L Parker, J; Vandenberg, C; Bridges, BC; Kilbaugh, TJ; Bembea, MM; Chima, RS; Potera, RM; Sandhu, HS; Barbaro, RP; et al. Flexible Bronchoscopy in Pediatric Venovenous Extracorporeal Membrane Oxygenation. Respiratory Care: a monthly science journal. 2022; 67:688-693.

Schafer, M; De Souza, HG; Paul, R; Riggs, R; Richardson, T; Conlon, P; Duffy, S; Foster, LZ; Gunderson, J; Hall, D; et al. Characteristics and Outcomes of Sepsis Presenting in Inpatient Pediatric Settings. Hospital Pediatrics. 2022; 12:1048-1059.

Schultz, K; Klein, M; Sucharew, H; McDonald, J; DeBlasio, D; Cooperstein, E; Poynter, S; Huggins, J; Real, FJ. The Impact of a Gamified Curriculum Using Kahoot! on Musculoskeletal Knowledge and Skill Acquisition Among Pediatric Residents. Academic Pediatrics. 2022; 22:1265-1270.

Serapiglia, V; Stephens, CA; Joshi, R; Aydin, E; Oria, M; Marotta, M; Peiro, JL; Varisco, BM. Fetal Tracheal Occlusion Increases Lung Basal Cells via Increased Yap Signaling. Frontiers in Pediatrics. 2022; 9:780166.

Smith, HA B; Besunder, JB; Betters, KA; Johnson, PN; Srinivasan, V; Stormorken, A; Farrington, E; Golianu, B; Godshall, AJ; Acinelli, L; et al. 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility. Pediatric Critical Care Medicine. 2022; 23:e74-e110.

Sosa, T; Mayer, B; Chakkalakkal, B; Drozd, A; Hater, K; Johnson, A; Nasr, A; Seger, BM; Meyer, R; Dewan, M; et al. Improving Shared Situation Awareness for High-risk Therapies in Hospitalized Children. Hospital Pediatrics. 2022; 12:37-46.

Stanski, NL; Gist, KM; Pickett, K; Brinton, JT; Sadlowski, J; Wong, HR; Mourani, P; Soranno, DE; Kendrick, J; Stenson, EK. Electrolyte derangements in critically ill children receiving balanced versus unbalanced crystalloid fluid resuscitation. BMC Nephrology. 2022; 23:388.

Stanski, NL; Slagle, CL; Gist, KM. Connecting Brain and Kidney: The Systemic Effects of Acute Kidney Injury After Cardiac Surgery. Annals of Thoracic Surgery. 2022; 114:2354-2355.

Straszewski, T; Ross, CA; Riley, C; Roy, B; Stiefel, MC. Testing the added value of self-reported health and well-being in understanding healthcare utilization and costs. Quality of Life Research. 2022; 31:3189-3199.

Sveen, W; Dewan, M; Dexheimer, JW. The Risk of Coding Racism into Pediatric Sepsis Care: The Necessity of Antiracism in Machine Learning. The Journal of Pediatrics. 2022; 247:129-132.

Tang Girdwood, S; Pavia, K; Paice, K; Hambrick, HR; Kaplan, J; Vinks, AA. β-lactam precision dosing in critically ill children: Current state and knowledge gaps. Frontiers in Pharmacology. 2022; 13:1044683.

Traube, C; Tucci, M; Nellis, ME; Avery, KL; McQuillen, PS; Fitzgerald, JC; Muszynski, JA; Cholette, JM; Schwarz, AJ; Stalets, EL; et al. Transfusion-Associated Delirium in Children: No Difference Between Short Storage Versus Standard Issue RBCs. Critical Care Medicine. 2022; 50:173-182.

Trinidad, S; Brokamp, C; Huertas, AM; Beck, AF; Riley, CL; Rasnick, E; Falcone, R; Kotagal, M. Use Of Area-Based Socioeconomic Deprivation Indices: A Scoping Review And Qualitative Analysis. Health Affairs. 2022; 41:1804-1811.

Trinidad, S; Vancil, A; Brokamp, C; Moody, S; Gardner, D; Parsons, AA; Riley, C; Sahay, R; Sofer, N; Beck, AF; et al. Relationships between socioeconomic deprivation and pediatric firearm-related injury at the neighborhood level. Journal of Trauma and Acute Care Surgery. 2022; 93:283-290.

Urban, C; Hayes, HV; Piraino, G; Wolfe, V; Lahni, P; O’Connor, M; Phares, C; Zingarelli, B. Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice. Frontiers in Immunology. 2022; 13:984298.

Vaara, ST; Bhatraju, PK; Stanski, NL; McMahon, BA; Liu, K; Joannidis, M; Bagshaw, SM. Subphenotypes in acute kidney injury: a narrative review. Critical Care (UK). 2022; 26:251.

Varisco, BM. In Memoriam: Hector R. Wong, MD (1963-2022). Pediatric Critical Care Medicine. 2022; 23:341-343.

Vitale, DS; Lahni, P; Hornung, L; Thompson, T; Farrell, PR; Lin, TK; Nathan, JD; Wong, HR; Abu-El-Haija, M. Matrix metalloproteinases and their inhibitors in pediatric severe acute pancreatitis. Editor, Rakonczay Z. PloS one. 2022; 17:e0261708.

Williams, JG; Joshi, R; Haslam, D; Yehya, N; Jones, RL; Paranjpe, A; Pujato, M; Roskin, KM; Lahni, PM; Wong, HR; et al. Multi-omic characterization of pediatric ARDS via nasal brushings. Respiratory Research. 2022; 23:181.