Huppert Lab

Adams, JM; Huppert, KA; Castro, EC; Lopez, MF; Niknejad, N; Subramanian, S; Zarrin-Khameh, N; Finegold, MJ; Huppert, SS; Jafar-Nejad, H. Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille Syndrome. Hepatology. 2020; 71:1331-1349.

Huppert, SS; Iwafuchi-Doi, M. Molecular regulation of mammalian hepatic architecture. Current Topics in Developmental Biology. 2019; 132:91-136.

Schaub, JR; Huppert, KA; Kurial, SN T; Hsu, BY; Cast, AE; Donnelly, B; Karns, RA; Chen, F; Rezvani, M; Luu, HY; et al. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. 2018; 557:247-251.

Broadus, MR; Chen, TW; Neitzel, LR; Ng, VH; Jodoin, JN; Lee, LA; Salic, A; Robbins, DJ; Capobianco, AJ; Patton, JG; et al. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. 2016; 15:1920-1929.

Hayashi, H; Osaka, S; Sakabe, K; Fukami, A; Kishimoto, E; Aihara, E; Sabu, Y; Mizutani, A; Kusuhara, H; Naritaka, N; et al. Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Stem Cell Reports. 2021; 16:309-323.

Adams, JM; Huppert, KA; Castro, EC; Lopez, MF; Niknejad, N; Subramanian, S; Zarrin-Khameh, N; Finegold, MJ; Huppert, SS; Jafar-Nejad, H. Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille Syndrome. Hepatology. 2020; 71:1331-1349.

Huppert, SS; Iwafuchi-Doi, M. Molecular regulation of mammalian hepatic architecture. Current Topics in Developmental Biology. 2019; 132:91-136.

Huppert, SS; Campbell, KM. Bile Duct Development and the Notch Signaling Pathway. Alagille Syndrome. 2018.

Ng, VH; Hang, BI; Sawyer, LM; Neitzel, LR; Crispi, EE; Rose, KL; Popay, TM; Zhong, A; Lee, LA; Tansey, WP; et al. Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling. Journal of Cell Science. 2018; 131.

Schaub, JR; Huppert, KA; Kurial, SN T; Hsu, BY; Cast, AE; Donnelly, B; Karns, RA; Chen, F; Rezvani, M; Luu, HY; et al. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. 2018; 557:247-251.

Soini, T; Pihlajoki, M; Andersson, N; Lohi, J; Huppert, KA; Rudnick, DA; Huppert, SS; Wilson, DB; Pakarinen, MP; Heikinheimo, M. Transcription factor GATA6: a novel marker and putative inducer of ductal metaplasia in biliary atresia. American Journal of Physiology - Gastrointestinal and Liver Physiology. 2018; 314:G547-G558.

Broadus, MR; Chen, TW; Neitzel, LR; Ng, VH; Jodoin, JN; Lee, LA; Salic, A; Robbins, DJ; Capobianco, AJ; Patton, JG; et al. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. 2016; 15:1920-1929.