Herr Lab
Publications

Publications

Selected Publications

Yarawsky, AE; Hopkins, JB; Chatzimagas, L; Hub, JS; Herr, AB. Solution Structural Studies of Pre-amyloid Oligomer States of the Biofilm Protein Aap. Journal of Molecular Biology. 2022; 434(16):167708.

Erickson, JJ; Archer-Hartmann, S; Yarawsky, AE; Miller, JLC; Seveau, S; Shao, T-Y; Severance, AL; Miller-Handley, H; Wu, Y; Pham, G; Lau, JTY; Azadi, P; Herr, AB; Way, SS. Pregnancy enables antibody protection against intracellular infection. Nature. 2022; 606(7915):769-775.

Gonzalez, T; Stevens, ML; Baatyrbek Kyzy, A; Alarcon, R; He, H; Kroner, JW; Spagna, D; Grashel, B; Sidler, E; Martin, LJ; Biagini Myers, JM; Khurana Hershey, GK; Herr, AB. Biofilm propensity of Staphylococcus aureus skin isolates is associated with increased atopic dermatitis severity and barrier dysfunction in the MPAACH pediatric cohort. Allergy. European Journal of Allergy and Clinical Immunology. 2021; 76(1):302-313.

Yarawsky, AE; Herr, AB. The staphylococcal biofilm protein Aap forms a tetrameric species as a necessary intermediate before amyloidogenesis. Journal of Biological Chemistry. 2020; 295(37):12840-12850.

Yarawsky, AE; Johns, SL; Schuck, P; Herr, AB. The biofilm adhesion protein Aap from Staphylococcus epidermidis forms zinc-dependent amyloid fibers. Journal of Biological Chemistry. 2020; 295(14):4411-4427.

Posgai, MT; Tonddast-Navaei, S; Jayasinghe, M; Ibrahim, GM; Stan, G; Herr, AB. FcαRI binding at the IgA1 CH2-CH3 interface induces long-range conformational changes that are transmitted to the hinge region. Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(38):E8882-E8891.

Shelton, CL; Conrady, DG; Herr, AB. Functional consequences of B-repeat sequence variation in the staphylococcal biofilm protein Aap: deciphering the assembly code. Biochemical Journal. 2017; 474(3):427-443.

Zhou, L; Hinerman, JM; Blaszczyk, M; Miller, JLC; Conrady, DG; Barrow, AD; Chirgadze, DY; Bihan, D; Farndale, RW; Herr, AB. Structural basis for collagen recognition by the immune receptor OSCAR. Blood. 2016; 127(5):529-537.

Strait, RT; Posgai, MT; Mahler, A; Barasa, N; Jacob, CO; Köhl, J; Ehlers, M; Stringer, K; Shanmukhappa, SK; Witte, D; Hossain, MM; Khodoun, M; Herr, AB; Finkelman, FD. IgG1 protects against renal disease in a mouse model of cryoglobulinaemia. Nature. 2015; 517(7535):501-504.

Conrady, DG; Wilson, JJ; Herr, AB. Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110(3):E202-E211.

Conrady, DG; Brescia, CC; Horii, K; Weiss, AA; Hassett, DJ; Herr, AB. A zinc-dependent adhesion module is responsible for intercellular adhesion in staphylococcal biofilms. Proceedings of the National Academy of Sciences of the United States of America. 2008; 105(49):19456-19461.

Horii, K; Kahn, ML; Herr, AB. Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI. Blood. 2006; 108(3):936-942.

Herr, AB; Ballister, ER; Bjorkman, PJ. Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc. Nature. 2003; 423(6940):614-620.

Ornitz, DM; Herr, AB; Nilsson, M; Westman, J; Svahn, CM; Waksman, G. FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science. 1995; 268(5209):432-436.

Heuer, LS; Sweeney, N; Rojas, M; Zhang, W; Mendelsohn, AR; Huang, M; Yu, B; Ackerman, P; Wei, Q; Herr, AB; Larrick, JW; Ridgway, WM. Higher order receptor clustering due to the IgG3 subclass is necessary for TLR4 signaling and tolerance induction by novel human anti-TLR4 antibodies. mAbs. 2025; 17(1):2515415.

Yarawsky, AE; Herr, AB. Assembly landscape of the complete B-repeat superdomain from Staphylococcus epidermidis strain 1457. Biophysical Journal. 2025; 124(2):363-378.

Thorman, AW; Reigle, J; Chutipongtanate, S; Yang, J; Shamsaei, B; Pilarczyk, M; Fazel-Najafabadi, M; Adamczak, R; Kouril, M; Bhatnagar, S; Hildeman, DA; Medvedovic, M; Herr, AB; Meller, J. Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science Advances. 2024; 10(35):eadj3010.

Devore, SB; Schuetz, M; Alvey, L; Lujan, H; Ochayon, DE; Williams, L; Chang, WC; Filuta, A; Ruff, B; Kothari, A; Keles, S; Milner, JD; Supp, DM; Khurana Hershey, GK. Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease. Cell reports. 2024; 43(8):114589.

Xu, R-G; Tiede, C; Calabrese, AN; Cheah, LT; Adams, TL; Gauer, JS; Hindle, MS; Webb, BA; Yates, DM; Slater, A; Herr, AB; Tomlinson, DC; Watson, SP; Ariëns, RAS. Affimer reagents as tool molecules to modulate platelet GPVI-ligand interactions and specifically bind GPVI dimer. Blood advances. 2024; 8(15):3917-3928.

Webb, JA; Farrow, E; Cain, B; Yuan, Z; Yarawsky, AE; Schoch, E; Gagliani, EK; Herr, AB; Gebelein, B; Kovall, RA. Cooperative Gsx2-DNA binding requires DNA bending and a novel Gsx2 homeodomain interface. Nucleic Acids Research (NAR). 2024; 52(13):7987-8002.

Mills, KB; Maciag, JJ; Wang, C; Crawford, JA; Enroth, TJ; Keim, KC; Dufrêne, YF; Robinson, DA; Fey, PD; Herr, AB; Horswill, AR. Staphylococcus aureus skin colonization is mediated by SasG lectin variation. Cell reports. 2024; 43(4):114022.

Yarawsky, AE; Ori, AL; English, LR; Whitten, ST; Herr, AB. Convergent behavior of extended stalk regions from staphylococcal surface proteins with widely divergent sequence patterns. Protein Science. 2023; 32(8):e4707.

Yarawsky, AE; Dinu, V; Harding, SE; Herr, AB. Strong non-ideality effects at low protein concentrations: considerations for elongated proteins. European Biophysics Journal. 2023; 52(4-5):427-438.

Yadav, R; Shaikh, T; Tikole, S; Herr, AB; Fitzkee, NC. 1H, 15N, and 13C chemical shift backbone resonance NMR assignment of the accumulation-associated protein (Aap) lectin domain from Staphylococcus epidermidis. Biomolecular NMR Assignments. 2023; 17(1):95-99.

Kleven, RT; Huang, S; Ford, SM; Sakthivel, K; Thomas, SR; Zuccarello, M; Herr, AB; Holland, CK. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound in Medicine and Biology. 2023; 49(2):539-548.

Kappes, EC; Kattamuri, C; Czepnik, M; Yarawsky, AE; Brûlé, E; Wang, Y; Ongaro, L; Herr, AB; Walton, KL; Bernard, DJ; Thompson, TB. Follistatin Forms a Stable Complex With Inhibin A That Does Not Interfere With Activin A Antagonism. Endocrinology. 2023; 164(3).

Smith, CA; Sonneson, GJ; Hoey, RJ; Hinerman, JM; Sheehy, K; Walter, R; Herr, AB; Horn, JR. Molecular recognition requires dimerization of a VHH antibody. mAbs. 2023; 15(1):2215363.

Wang, C; Chantraine, C; Viljoen, A; Herr, AB; Fey, PD; Horswill, AR; Mathelié-Guinlet, M; Dufrêne, YF. The staphylococcal biofilm protein Aap mediates cell-cell adhesion through mechanically distinct homophilic and lectin interactions. PNAS Nexus. 2022; 1(5):pgac278.

Yarawsky, AE; Hopkins, JB; Chatzimagas, L; Hub, JS; Herr, AB. Solution Structural Studies of Pre-amyloid Oligomer States of the Biofilm Protein Aap. Journal of Molecular Biology. 2022; 434(16):167708.

Erickson, JJ; Archer-Hartmann, S; Yarawsky, AE; Miller, JLC; Seveau, S; Shao, T-Y; Severance, AL; Miller-Handley, H; Wu, Y; Pham, G; Lau, JTY; Azadi, P; Herr, AB; Way, SS. Pregnancy enables antibody protection against intracellular infection. Nature. 2022; 606(7915):769-775.

Locker, KCS; Kachapati, K; Wu, Y; Bednar, KJ; Adams, D; Patel, C; Tsukamoto, H; Heuer, LS; Aronow, BJ; Herr, AB; Ridgway, WM. Endosomal Sequestration of TLR4 Antibody Induces Myeloid-Derived Suppressor Cells and Reverses Acute Type 1 Diabetes. Diabetes. 2022; 71(3):470-482.

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