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Simultaneous skin biome and keratinocyte genomic capture reveals microbiome differences by depth of sampling.
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The staphylococcal biofilm protein Aap forms a tetrameric species as a necessary intermediate before amyloidogenesis.
Journal of Biological Chemistry.
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The biofilm adhesion protein Aap from Staphylococcus epidermidis forms zinc-dependent amyloid fibers.
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Gab3 is required for IL-2- and IL-15-induced NK cell expansion and limits trophoblast invasion during pregnancy.
Science Immunology.
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FcαRI binding at the IgA1 CH2-CH3 interface induces long-range conformational changes that are transmitted to the hinge region.
Proceedings of the National Academy of Sciences of the United States of America.
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Functional consequences of B-repeat sequence variation in the staphylococcal biofilm protein Aap: deciphering the assembly code.
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The Proline/Glycine-Rich Region of the Biofilm Adhesion Protein Aap Forms an Extended Stalk that Resists Compaction.
Journal of Molecular Biology.
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Structural basis for collagen recognition by the immune receptor OSCAR.
Blood.
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IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.
Nature: New biology.
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Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms.
Proceedings of the National Academy of Sciences of the United States of America.
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A zinc-dependent adhesion module is responsible for intercellular adhesion in staphylococcal biofilms.
Proceedings of the National Academy of Sciences of the United States of America.
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Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI.
Blood.
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Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc.
Nature: New biology.
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Bivalent binding of IgA1 to FcalphaRI suggests a mechanism for cytokine activation of IgA phagocytosis.
Journal of Molecular Biology.
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327:645-657.
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Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes.
Journal of Biological Chemistry.
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FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides.
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