Quattrocelli Lab

Publications

Durumutla, HB; Villa, C; Panta, M; Wintzinger, M; Pragasam, AD P; Miz, K; Quattrocelli, M. Comprehensive Analyses of Muscle Function, Lean and Muscle Mass, and Myofiber Typing in Mice. Bio-protocol. 2023; 13:e4617.

Wintzinger, M; Miz, K; York, A; Demonbreun, AR; Molkentin, JD; McNally, EM; Quattrocelli, M. Effects of Glucocorticoids in Murine Models of Duchenne and Limb-Girdle Muscular Dystrophy. Methods in molecular biology (Clifton, N.J.). 2023; 2587:467-478.

Wintzinger, M; Panta, M; Miz, K; Prabakaran, AD; Durumutla, HB; Sargent, M; Peek, CB; Bass, J; Molkentin, JD; Quattrocelli, M. Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids. Molecular Metabolism. 2022; 62:101528.

Quattrocelli, M; Wintzinger, M; Miz, K; Panta, M; Prabakaran, AD; Barish, GD; Chandel, NS; McNally, EM. Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin. The Journal of Experimental Medicine. 2022; 219:e20211906.

Quattrocelli, M; Wintzinger, M; Miz, K; Levine, DC; Peek, CB; Bass, J; McNally, EM. Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α. Science Advances. 2022; 8:eabm1189.

Quattrocelli, M; Zelikovich, AS; Jiang, Z; Peek, CB; Demonbreun, AR; Kuntz, NL; Barish, GD; Haldar, SM; Bass, J; McNally, EM. Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. JCI insight. 2019; 4:e132402.

Giacomazzi, G; Holvoet, B; Trenson, S; Caluwe, E; Kravic, B; Grosemans, H; Cortes-Calabuig, A; Deroose, CM; Huylebroeck, D; Hashemolhosseini, S; et al. MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors. Nature Communications. 2017; 8:1249.

Quattrocelli, M; Capote, J; Ohiri, JC; Warner, JL; Vo, AH; Earley, JU; Hadhazy, M; Demonbreun, AR; Spencer, MJ; McNally, EM. Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury. Editor, Cox GA. PLoS Genetics. 2017; 13:e1007070.

Quattrocelli, M; Barefield, DY; Warner, JL; Vo, AH; Hadhazy, M; Earley, JU; Demonbreun, AR; McNally, EM. Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy. The Journal of Clinical Investigation. 2017; 127:2418-2432.

Quattrocelli, M; Swinnen, M; Giacomazzi, G; Camps, J; Barthelemy, I; Ceccarelli, G; Caluwe, E; Grosemans, H; Thorrez, L; Pelizzo, G; et al. Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. The Journal of Clinical Investigation. 2015; 125:4463-4482.

Quattrocelli, M; Crippa, S; Montecchiani, C; Camps, J; Cornaglia, AI; Boldrin, L; Morgan, J; Calligaro, A; Casasco, A; Orlacchio, A; et al. Long-term miR-669a therapy alleviates chronic dilated cardiomyopathy in dystrophic mice. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease. 2013; 2:e000284.

Quattrocelli, M; Palazzolo, G; Floris, G; Schoffski, P; Anastasia, L; Orlacchio, A; Vandendriessche, T; Chuah, MK L; Cossu, G; Verfaillie, C; et al. Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs. The Journal of pathology and bacteriology. 2011; 223:593-603.

Krishna, S; Echevarria, KG; Reed, CH; Eo, H; Wintzinger, M; Quattrocelli, M; Valentine, RJ; Selsby, JT. A fat- and sucrose-enriched diet causes metabolic alterations in mdx mice. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2023; 325:R692-R711.

Prabakaran, A; Wintzinger, M; Piczer, K; Miz, K; Walton, A; Bindu Durumutla, H; Quattrocelli, M. OR33-04 Mechanistic Dissection Of Circadian-Specific Glucocorticoid Effects On Exercise Tolerance And Muscle Glucose Utilization. Journal of the Endocrine Society. 2023; 7:bvad114.1772.

Farini, A; Tripodi, L; Villa, C; Strati, F; Facoetti, A; Baselli, G; Troisi, J; Landolfi, A; Lonati, C; Molinaro, D; et al. Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice. EMBO Molecular Medicine. 2023; 15:e16244.

Durumutla, HB; Villa, C; Panta, M; Wintzinger, M; Pragasam, AD P; Miz, K; Quattrocelli, M. Comprehensive Analyses of Muscle Function, Lean and Muscle Mass, and Myofiber Typing in Mice. Bio-protocol. 2023; 13:e4617.

Cossu, G; Tonlorenzi, R; Brunelli, S; Sampaolesi, M; Messina, G; Azzoni, E; Benedetti, S; Biressi, S; Bonfanti, C; Bragg, L; et al. Mesoangioblasts at 20: From the embryonic aorta to the patient bed. Frontiers in Genetics. 2023; 13:1056114.

Fischer, JA; Monroe, TO; Pesce, LL; Sawicki, KT; Quattrocelli, M; Bauer, R; Kearns, SD; Wolf, MJ; Puckelwartz, MJ; Mcnally, EM. Opposing effects of genetic variation in MTCH2 for obesity versus heart failure. Human Molecular Genetics. 2023; 32:15-29.

Wintzinger, M; Miz, K; York, A; Demonbreun, AR; Molkentin, JD; McNally, EM; Quattrocelli, M. Effects of Glucocorticoids in Murine Models of Duchenne and Limb-Girdle Muscular Dystrophy. Methods in molecular biology (Clifton, N.J.). 2023; 2587:467-478.

Yedigaryan, L; Martínez-Sarrà, E; Giacomazzi, G; Giarratana, N; van der Veer, BK; Rotini, A; Querceto, S; Grosemans, H; Cortés-Calabuig, Á; Salucci, S; et al. Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions. Frontiers in Immunology. 2022; 13:977617.

Kimura, M; Iguchi, T; Iwasawa, K; Dunn, A; Thompson, WL; Yoneyama, Y; Chaturvedi, P; Zorn, AM; Wintzinger, M; Quattrocelli, M; et al. En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. Cell. 2022; 185:4216-4232.e16.

Quattrocelli, M; Wintzinger, M; Miz, K; Panta, M; Durumutla, HB; Prabakaran, AD. Abstract P3035: Time-of-intake Regulates Glucocorticoid Effects On Heart Metabolism And Function Through Cardiomyocyte-autonomous Mechanisms. Circulation Research. 2022; 131:ap3035.

Wintzinger, M; Panta, M; Miz, K; Prabakaran, AD; Durumutla, HB; Sargent, M; Peek, CB; Bass, J; Molkentin, JD; Quattrocelli, M. Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids. Molecular Metabolism. 2022; 62:101528.

Prabakaran, AD; Panta, M; Quattrocelli, M. Commentary for “antagonizing urotensin receptor is a novel therapeutic strategy for glucocorticoid‐induced skeletal muscle atrophy”. Clinical and Translational Discovery. 2022; 2.

Quattrocelli, M; Wintzinger, M; Miz, K; Panta, M; Prabakaran, AD; Barish, GD; Chandel, NS; McNally, EM. Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin. The Journal of Experimental Medicine. 2022; 219:e20211906.

Salamone, IM; Quattrocelli, M; Barefield, DY; Page, PG; Tahtah, I; Hadhazy, M; Tomar, G; McNally, EM. Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. The Journal of Clinical Investigation. 2022; 132:e149828.

Jiang, Z; Elsarrag, SZ; Duan, Q; LaGory, EL; Wang, Z; Alexanian, M; McMahon, S; Rulifson, IC; Winchester, S; Wang, Y; et al. KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation. Science Advances. 2022; 8:eabj2917.

Quattrocelli, M; Wintzinger, M; Miz, K; Levine, DC; Peek, CB; Bass, J; McNally, EM. Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α. Science Advances. 2022; 8:eabm1189.

Grassi, F; Falcone, S. Report and Abstracts of the 18th Meeting of the Interuniversity Institute of Myology: Virtual meeting, October 21-24, 2021. European Journal of Translational Myology. 2021; 31:10270.

Demonbreun, AR; Fallon, KS; Oosterbaan, CC; Vaught, LA; Reiser, NL; Bogdanovic, E; Velez, MP; Salamone, IM; Page, PG T; Hadhazy, M; et al. Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Science Translational Medicine. 2021; 13:eabf0376.

Ronzoni, FL; Giarratana, N; Crippa, S; Quattrocelli, M; Cassano, M; Ceccarelli, G; Benedetti, L; Van Herck, J; De Angelis, MG C; Vitale, M; et al. Guide Cells Support Muscle Regeneration and Affect Neuro-Muscular Junction Organization. International Journal of Molecular Sciences. 2021; 22:1939.

Giacomazzi, G; Giovannelli, G; Rotini, A; Costamagna, D; Quattrocelli, M; Sampaolesi, M. Isolation of Mammalian Mesoangioblasts: A Subset of Pericytes with Myogenic Potential. Methods in molecular biology (Clifton, N.J.). 2021; 2235:155-167.

Quattrocelli, M; Zelikovich, AS; Salamone, IM; Fischer, JA; McNally, EM. Mechanisms and Clinical Applications of Glucocorticoid Steroids in Muscular Dystrophy. Journal of Neuromuscular Diseases. 2021; 8:39-52.

Zelikovich, AS; Quattrocelli, M; McNally, EM; Kuntz, NL. Improved Metabolic and Bone Health in Boys with Duchenne Muscular Dystrophy Treated with High Dose Pulse Weekend Corticosteroids compared to Daily Dosing (21). Neurology. 2020; 94.

Demonbreun, AR; Wyatt, EJ; Fallon, KS; Oosterbaan, CC; Page, PG; Hadhazy, M; Quattrocelli, M; Barefield, DY; McNally, EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. DMM Disease Models and Mechanisms. 2020; 13:dmm040832.

van Tienen, F; Zelissen, R; Timmer, E; van Gisbergen, M; Lindsey, P; Quattrocelli, M; Sampaolesi, M; Mulder-den Hartog, E; de Coo, I; Smeets, H. Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy. Stem Cell Research and Therapy. 2019; 10:405.

Quattrocelli, M; Zelikovich, AS; Jiang, Z; Peek, CB; Demonbreun, AR; Kuntz, NL; Barish, GD; Haldar, SM; Bass, J; McNally, EM. Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. JCI insight. 2019; 4:e132402.

Zelikovich, AS; Quattrocelli, M; Salamone, IM; Kuntz, NL; McNally, EM. Moderate exercise improves function and increases adiponectin in the mdx mouse model of muscular dystrophy. Scientific Reports. 2019; 9:5770.

Demonbreun, AR; Fallon, KS; Oosterbaan, CC; Bogdanovic, E; Warner, JL; Sell, JJ; Page, PG; Quattrocelli, M; Barefield, DY; McNally, EM. Recombinant annexin A6 promotes membrane repair and protects against muscle injury. The Journal of Clinical Investigation. 2019; 129:4657-4670.

Kramerova, I; Kumagai-Cresse, C; Ermolova, N; Mokhonova, E; Marinov, M; Capote, J; Becerra, D; Quattrocelli, M; Crosbie, RH; Welch, E; et al. Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases. Human Molecular Genetics. 2019; 28:3431-3442.

Zelikovich, AS; Oswald, T; Quattrocelli, M; McNally, EM; Rao, VK; Kuntz, NL. Developing Tools to Assess Changes Associated with Aerobic Exercise in Boys with Duchenne Muscular Dystrophy (P1.6-069). Neurology. 2019; 92.