Waxman Lab

Rydeen, A.B. and Waxman, J.S. (2016) Cyp26 enzymes facilitate second heart field progenitor addition and maintenance of ventricular integrity. PLOS Biology. 14(11):e2000504.

Adolfi, M.C., Herpin, A., Regensburger, M., Sacquegno, J., Waxman, J.S., and Schartl, M. (2016) Retinoic acid and meiosis induction in adult versus embryonic gonads of medaka. Scientific Reports. Sep 28. 6:34281.

D'Aniello E, Waxman JS. Input overload: Contributions of retinoic acid signaling feedback mechanisms to heart development and teratogenesis. Dev Dyn. 2015 Mar;244(3):513-23.

D'Aniello E, Ravisankar P, Waxman JS. Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis. PLoS One. 2015 Sep 22;10(9):e0138588. 

Rydeen A, Voisin N, D'Aniello E, Ravisankar P, Devignes CS, Waxman JS. Excessive feedback of Cyp26a1 promotes cell non-autonomous loss of retinoic acid signaling. Dev Biol. 2015 Sep 1;405(1):47-55.

Mandal A, Waxman J. Retinoic acid negatively regulates dact3b expression in the hindbrain of zebrafish embryos. Gene Expr Patterns. 2014 Nov;16(2):122-9.

Rydeen AB, Waxman JS. Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm. Development. 2014 Apr;141(8):1638-48.

D’Aniello E, Rydeen A, Anderson J, Mandal A., Waxman JS.Depletion of retinoic acid receptors initiates a novel positive feedback mechanism that promotes teratogenic increases in retinoic acid. PLoS Genet. 2013 Aug. 9(8); e1003689.

Sorrell MR, Dohn TE, D’Aniello E, Waxman JS. Tcf7l1 proteins cell autonomously restrict cardiomyocyte and promote endothelial specification in zebrafish. Dev Biol. 2013 380(2); 199-210. 

Mandal A, Rydeen A, Anderson J, Sorrell MR, Zygmunt T, Torres-Vázquez J, Waxman JS.Transgenic retinoic acid sensor lines in zebrafish indicate regions of available embryonic retinoic acid. Developmental Dynamics. 2013 Aug. 242(8); 989-1000. 

Sorrell MR, Waxman JS. Restraint of Fgf8 signaling by retinoic acid signaling is required for proper heart and forelimb formation. Dev. Biol. 2011 Oct 1;358(1):44-55.

Waxman JS, Yelon D. Zebrafish retinoic acid receptors function as context-dependent transcriptional activators. Dev Biol. 2011 352:128-40.

Waxman JS, Yelon D. Increased Hox activity mimics the teratogenic effects of excess retinoic acid signaling. Dev Dyn. 2009 May;238(5):1207-13.

Linville A, Radtke K, Waxman JS, Yelon D, Schilling TF. Combinatorial roles for zebrafish retinoic acid receptors in the hindbrain, limbs and pharyngeal arches. Dev Biol. 2009 Jan 1;325(1):60-70.

Waxman JS, Yelon D. Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors. Dev Dyn. 2007 Feb;236(2):587-95.

Waxman JS. Regulation of the early expression patterns of the zebrafish Dishevelled-interacting proteins Dapper1 and Dapper2. Dev Dyn. 2005 May;233(1):194-200.

Waxman JS, Hocking AM, Stoick CL, Moon RT. Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes. Development. 2004 Dec;131(23):5909-21.

Waxman JS, Moon RT. Form and functions of the gastrula organizer in zebrafish. The Organizer(edit.  Horst Grunz).Springer Press. (London, England). pp. 375-393. 2003.

Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, Khlebtsova N, Fox EP, Earnest T, Moon RT. Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation. Dev Cell. 2002 Apr;2(4):449-61.

Lekven AC, Thorpe CJ, Waxman JS, Moon RT. Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning. Dev Cell. 2001 Jul;1(1):103-14.