Devarajan Lab

Bowers, SL K; Davis-Rodriguez, S; Thomas, ZM; Rudomanova, V; Bacon, WC; Beiersdorfer, A; Ma, Q; Devarajan, P; Blaxall, BC. Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2019; 316:F1293-F1298.

Schuh, MP; Bennett, MR; Lane, A; Jodele, S; Laskin, BL; Devarajan, P. Haptoglobin degradation product as a novel serum biomarker for hematopoietic stem cell transplant-associated thrombotic microangiopathy. Pediatric Nephrology. 2019; 34:865-871.

Aljaberi, N; Bennett, M; Brunner, HI; Devarajan, P. Proteomic profiling of urine: implications for lupus nephritis. Expert Review of Proteomics. 2019; 16:303-313.

Turnier, JL; Brunner, HI; Bennett, M; Aleed, A; Gulati, G; Haffey, WD; Thornton, S; Wagner, M; Devarajan, P; Witte, D; et al. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology. 2019; 58:321-330.

Carpenter, SL; Goldman, J; Sherman, AK; Selewski, DT; Kallash, M; Tran, CL; Seamon, M; Katsoufis, C; Ashoor, I; Hernandez, J; et al. Association of infections and venous thromboembolism in hospitalized children with nephrotic syndrome. Pediatric Nephrology. 2019; 34:261-267.

Brunner, HI; Gulati, G; Klein-Gitelman, MS; Rouster-Stevens, KA; Tucker, L; Ardoin, SP; Onel, KB; Mainville, R; Turnier, J; Aydin, PO A; et al. Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus. Pediatric Nephrology. 2019; 34:117-128.

Chihanga, T; Ruby, HN; Ma, Q; Bashir, S; Devarajan, P; Kennedy, MA. NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2018; 315:F1159-F1173.

Albert, C; Albert, A; Bellomo, R; Kropf, S; Devarajan, P; Westphal, S; Baraki, H; Kutschka, I; Butter, C; Haase, M; et al. Urinary neutrophil gelatinase-associated lipocalin-guided risk assessment for major adverse kidney events after open-heart surgery. Biomarkers in medicine. 2018; 12:975-985.

Lang, J; Katz, R; Ix, JH; Gutierrez, OM; Peralta, CA; Parikh, CR; Satterfield, S; Petrovic, S; Devarajan, P; Bennett, M; et al. Association of serum albumin levels with kidney function decline and incident chronic kidney disease in elders. Nephrology Dialysis Transplantation. 2018; 33:986-992.

Greenberg, JH; Devarajan, P; Thiessen-Philbrook, HR; Krawczeski, C; Parikh, CR; Zappitelli, M; Consortium, TR I B E-A K. Kidney injury biomarkers 5 years after AKI due to pediatric cardiac surgery. Pediatric Nephrology. 2018; 33:1069-1077.

Benoit, SW; Devarajan, P. Acute kidney injury: emerging pharmacotherapies in current clinical trials. Pediatric Nephrology. 2018; 33:779-787.

Greenberg, JH; Zappitelli, M; Jia, Y; Thiessen-Philbrook, HR; de Fontnouvelle, CA; Wilson, FP; Coca, S; Devarajan, P; Parikh, CR. Biomarkers of AKI Progression after Pediatric Cardiac Surgery. Journal of the American Society of Nephrology : JASN. 2018; 29:1549-1556.

Bennett, MR; Devarajan, P. The future role of proteomics in the understanding of acute kidney injury. Expert Review of Proteomics. 2018; 15:191-192.

Bennett, MR; Pyles, O; Ma, Q; Devarajan, P. Preoperative levels of urinary uromodulin predict acute kidney injury after pediatric cardiopulmonary bypass surgery. Pediatric Nephrology. 2018; 33:521-526.

Chihanga, T; Ma, Q; Nicholson, JD; Ruby, HN; Edelmann, RE; Devarajan, P; Kennedy, MA. NMR spectroscopy and electron microscopy identification of metabolic and ultrastructural changes to the kidney following ischemia-reperfusion injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2018; 314:F154-F166.

Goldstein, BH; Goldstein, SL; Devarajan, P; Zafar, F; Kwiatkowski, DM; Marino, BS; Morales, DL S; Krawczeski, CD; Cooper, DS. First-stage palliation strategy for univentricular heart disease may impact risk for acute kidney injury. Cardiology in the Young. 2018; 28:93-100.

Dong, L; Ma, Q; Bennett, M; Devarajan, P. Urinary biomarkers of cell cycle arrest are delayed predictors of acute kidney injury after pediatric cardiopulmonary bypass. Pediatric Nephrology. 2017; 32:2351-2360.

Varnell, CD; Goldstein, SL; Devarajan, P; Basu, RK. Impact of Near Real-Time Urine Neutrophil Gelatinase–Associated Lipocalin Assessment on Clinical Practice. Kidney International Reports. 2017; 2:1243-1249.

Bennett, MR; Ma, Q; Ying, J; Devarajan, P; Brunner, H. Effects of age and gender on reference levels of biomarkers comprising the pediatric Renal Activity Index for Lupus Nephritis (p-RAIL). Pediatric Rheumatology Online Journal. 2017; 15.

Sterling, M; Al-Ismaili, Z; McMahon, KR; Piccioni, M; Pizzi, M; Mottes, T; Lands, LC; Abish, S; Fleming, AJ; Bennett, MR; et al. Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy. Pediatric Blood and Cancer. 2017; 64:e26538-e26538.

Nehus, E; Kaddourah, A; Bennett, M; Pyles, O; Devarajan, P. Subclinical Kidney Injury in Children Receiving Nonsteroidal Anti-Inflammatory Drugs After Cardiac Surgery. The Journal of Pediatrics. 2017; 189:175-180.

Quinn, CT; Saraf, SL; Gordeuk, VR; Fitzhugh, CD; Creary, SE; Bodas, P; George, A; Raj, AB; Nero, AC; Terrell, CE; et al. Losartan for the nephropathy of sickle cell anemia: A phase-2, multicenter trial. American Journal of Hematology. 2017; 92:E520-E528.

Pleasant, L; Ma, Q; Devarajan, M; Parameswaran, P; Drake, K; Siroky, B; Shay-Winkler, K; Robbins, J; Devarajan, P. Increased susceptibility to structural acute kidney injury in a mouse model of presymptomatic cardiomyopathy. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2017; 313:F699-F705.

Gulati, G; Bennett, MR; Abulaban, K; Song, H; Zhang, X; Ma, Q; Brodsky, SV; Nadasdy, T; Haffner, C; Wiley, K; et al. Prospective validation of a novel renal activity index of lupus nephritis. Lupus. 2017; 26:927-936.

Brunner, HI; Bennett, MR; Gulati, G; Abulaban, K; Klein-Gitelman, MS; Ardoin, SP; Tucker, LB; Rouster-Stevens, KA; Witte, D; Ying, J; et al. Urine Biomarkers to Predict Response to Lupus Nephritis Therapy in Children and Young Adults. The Journal of rheumatology. 2017; 44:1239-1248.

Garimella, PS; Bartz, TM; Ix, JH; Chonchol, M; Shlipak, MG; Devarajan, P; Bennett, MR; Sarnak, MJ. Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study. American Journal of Kidney Diseases. 2017; 69:744-751.

Palermo, J; Dart, AB; De Mello, A; Devarajan, P; Gottesman, R; Guerra, GG; Hansen, G; Joffe, AR; Mammen, C; Majesic, N; et al. Biomarkers for Early Acute Kidney Injury Diagnosis and Severity Prediction: A Pilot Multicenter Canadian Study of Children Admitted to the ICU. Pediatric Critical Care Medicine. 2017; 18:e235-e244.

Garimella, PS; Katz, R; Ix, JH; Fried, LF; Kritchevsky, SB; Devarajan, P; Bennett, MR; Parikh, CR; Shlipak, MG; Harris, TB; et al. Association of urinary uromodulin with kidney function decline and mortality: the health ABC study. Clinical Nephrology. 2017; 87:278-286.

Bennett, MR; Pleasant, LT; Haffner, C; Ma, Q; Haffey, WD; Ying, J; Wagner, M; Greis, KD; Devarajan, P. A novel biomarker panel to identify steroid resistance in childhood idiopathic nephrotic syndrome. Biomarker Insights. 2017; 12:1177271917695832-117727191769583.

Forster, CS; Devarajan, P. Neutrophil gelatinase-associated lipocalin: utility in urologic conditions. Pediatric Nephrology. 2017; 32:377-381.

Devarajan, P. Acute kidney injury: still misunderstood and misdiagnosed. Nature Reviews Nephrology. 2017; 13:137-138.

Wikenheiser-Brokamp, KA; Klein, M; Hershey, GK K; Devarajan, P; DeWitt, TG; Loch, J; Strauss, AW; Muglia, LJ; Hostetter, MK. Evaluation of Fellows' CrossTalk Effectiveness in Promoting Transdisciplinary Networking and Research. The Journal of Pediatrics. 2017; 181:5-6.e3.

Garimella, PS; Jaber, BL; Tighiouart, H; Liangos, O; Bennett, MR; Devarajan, P; El-Achkar, TM; Sarnak, MJ. Association of Preoperative Urinary Uromodulin with AKI after Cardiac Surgery. Clinical journal of the American Society of Nephrology : CJASN. 2017; 12:10-18.

Kamal, FA; Travers, JG; Schafer, AE; Ma, Q; Devarajan, P; Blaxall, BC. G Protein-Coupled Receptor-G-Protein beta gamma-Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure. Journal of the American Society of Nephrology : JASN. 2017; 28:197-208.

Lau, L; Al-Ismaili, Z; Harel-Sterling, M; Pizzi, M; Caldwell, JS; Piccioni, M; Lands, LC; Mottes, T; Devarajan, P; Goldstein, SL; et al. Serum cystatin C for acute kidney injury evaluation in children treated with aminoglycosides. Pediatric Nephrology. 2017; 32:163-171.

Devarajan, P; Basu, RK. Sepsis-associated acute kidney injury-is it possible to move the needle against this syndrome?. Jornal de Pediatria. 2017; 93:1-3.

Bennett, MR; Devarajan, P. Characteristics of an Ideal Biomarker of Kidney Diseases. Biomarkers of Kidney Disease. : Elsevier; Elsevier; 2017.

Wang, Z; Ma, S; Zappitelli, M; Parikh, C; Wang, C; Devarajan, P. Penalized count data regression with application to hospital stay after pediatric cardiac surgery. Statistical Methods in Medical Research. 2016; 25:2685-2703.

Minevich, E; Devarajan, P; Lorenzo, AJ; Goldstein, SL; DeFoor, WR; Koyle, MA. Pediatric renal tumors. Clinical Pediatric Nephrology: Third Edition. : CRC Press; CRC Press; 2016.

Soto, K; Campos, P; Pinto, I; Rodrigues, B; Frade, F; Papoila, AL; Devarajan, P. The risk of chronic kidney disease and mortality are increased after community-acquired acute kidney injury. Kidney International. 2016; 90:1090-1099.

Greenberg, JH; Zappitelli, M; Devarajan, P; Thiessen-Philbrook, HR; Krawczeski, C; Li, S; Garg, AX; Coca, S; Parikh, CR; Consortium, TR I B E-A K. Kidney Outcomes 5 Years After Pediatric Cardiac Surgery The TRIBE-AKI Study. JAMA Pediatrics. 2016; 170:1071-1078.

Liu, KD; Siew, ED; Reeves, WB; Himmelfarb, J; Go, AS; Hsu, C; Bennett, MR; Devarajan, P; Ikizler, TA; Kaufman, JS; et al. Storage Time and Urine Biomarker Levels in the ASSESS-AKI Study. PLoS ONE. 2016; 11:e0164832-e0164832.

Ma, Q; Devarajan, SR; Devarajan, P. Amelioration of cisplatin-induced acute kidney injury by recombinant neutrophil gelatinase-associated lipocalin. Renal Failure. 2016; 38:1476-1482.

Brunner, HI; Bennett, MR; Abulaban, K; Klein-Gitelman, MS; O'Neil, KM; Tucker, L; Ardoin, SP; Rouster-Stevens, KA; Onel, KB; Singer, NG; et al. Development of a Novel Renal Activity Index of Lupus Nephritis in Children and Young Adults. Arthritis Care and Research. 2016; 68:1003-1011.

Devarajan, P; Jefferies, JL. Progression of chronic kidney disease after acute kidney injury. Progress in Pediatric Cardiology. 2016; 41:33-40.

Jefferies, JL; Devarajan, P. Early detection of acute kidney injury after pediatric cardiac surgery. Progress in Pediatric Cardiology. 2016; 41:9-16.

Erkan, E; Zhao, X; Setchell, K; Devarajan, P. Distinct urinary lipid profile in children with focal segmental glomerulosclerosis. Pediatric Nephrology. 2016; 31:581-588.

Abulaban, KM; Fall, N; Nunna, R; Ying, J; Devarajan, P; Grom, A; Bennett, M; Ardoin, SP; Brunner, HI. Relationship of cell-free urine MicroRNA with lupus nephritis in children. Pediatric Rheumatology Online Journal. 2016; 14.

Bennett, MR; Pordal, A; Haffner, C; Pleasant, L; Ma, Q; Devarajan, P. Urinary vitamin D-binding protein as a biomarker of steroid-resistant nephrotic syndrome. Biomarker Insights. 2016; 11:BMI.S31633-BMI.S31633.

Cooper, DS; Claes, D; Goldstein, SL; Bennett, MR; Ma, Q; Devarajan, P; Krawczeski, CD. Follow-Up Renal Assessment of Injury Long-Term After Acute Kidney Injury (FRAIL-AKI). Clinical journal of the American Society of Nephrology : CJASN. 2016; 11:21-29.

Schuh, MP; Nehus, E; Ma, Q; Haffner, C; Bennett, M; Krawczeski, CD; Devarajan, P. Long-term Stability of Urinary Biomarkers of Acute Kidney Injury in Children. American Journal of Kidney Diseases. 2016; 67:56-61.

Claes, DJ; Devarajan, P. Clinical consequences of congenital anomalies of the kidney and urinary tract. Congenital Anomalies of the Kidney and Urinary Tract: Clinical Implications in Children. : Springer International Publishing; Springer International Publishing; 2016.

Rheault, MN; Zhang, L; Selewski, DT; Kallash, M; Tran, CL; Seamon, M; Katsoufis, C; Ashoor, I; Hernandez, J; Supe-Markovina, K; et al. AKI in Children Hospitalized with Nephrotic Syndrome. Clinical journal of the American Society of Nephrology : CJASN. 2015; 10:2110-2118.

Koyner, JL; Coca, SG; Thiessen-Philbrook, H; Patel, UD; Shlipak, MG; Garg, AX; Parikh, CR; Raman, J; Jeevanandam, V; Akhter, S; et al. Urine biomarkers and perioperative acute kidney injury: The impact of preoperative estimated GFR. American Journal of Kidney Diseases. 2015; 66:1006-1014.

Garimella, PS; Biggs, ML; Katz, R; Ix, JH; Bennett, MR; Devarajan, P; Kestenbaum, BR; Siscovick, DS; Jensen, MK; Shlipak, MG; et al. Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. Kidney International. 2015; 88:1126-1134.

Greenberg, JH; Whitlock, R; Zhang, WR; Thiessen-Philbrook, HR; Zappitelli, M; Devarajan, P; Eikelboom, J; Kavsak, PA; Devereaux, PJ; Shortt, C; et al. Interleukin-6 and interleukin-10 as acute kidney injury biomarkers in pediatric cardiac surgery. Pediatric Nephrology. 2015; 30:1519-1527.

Klein, M; Hershey, GK K; Devarajan, P; Muglia, LJ; Wikenheiser-Brokamp, KA; Loch, J; Hostetter, MK; Strauss, AW; DeWitt, TG. Enhancing Pediatric Fellows' Research Training: Development of an Office of Pediatric Clinical Fellowships. The Journal of Pediatrics. 2015; 167:506-7.e1.

Moledina, DG; Parikh, CR; Garg, AX; Thiessen-Philbrook, H; Koyner, JL; Patel, UD; Devarajan, P; Shlipak, MG; Coca, SG; Consortium, TR I B E-A K. Association of Perioperative Plasma Neutrophil Gelatinase-Associated Lipocalin Levels with 3-Year Mortality after Cardiac Surgery: A Prospective Observational Cohort Study. PLoS ONE. 2015; 10:e0129619-e0129619.

Xiao, N; Devarajan, P; Inge, TH; Jenkins, TM; Bennett, M; Mitsnefes, MM. Subclinical kidney injury before and 1 year after bariatric surgery among adolescents with severe obesity. Obesity. 2015; 23:1234-1238.

Zappitelli, M; Greenberg, JH; Coca, SG; Krawczeski, CD; Li, S; Thiessen-Philbrook, HR; Bennett, MR; Devarajan, P; Parikh, CR; TRIBE-AKI, AK I. Association of Definition of Acute Kidney Injury by Cystatin C Rise With Biomarkers and Clinical Outcomes in Children Undergoing Cardiac Surgery. JAMA Pediatrics. 2015; 169:583-591.

Bennett, MR; Nehus, E; Haffner, C; Ma, Q; Devarajan, P. Pediatric reference ranges for acute kidney injury biomarkers. Pediatric Nephrology. 2015; 30:677-685.

Basu, RK; Donaworth, E; Siroky, B; Devarajan, P; Wong, HR. Loss of matrix metalloproteinase-8 is associated with worsened recovery after ischemic kidney injury. Renal Failure. 2015; 37:469-475.

Lagos-Arevalo, P; Palijan, A; Vertullo, L; Devarajan, P; Bennett, MR; Sabbisetti, V; Bonventre, JV; Ma, Q; Gottesman, RD; Zappitelli, M. Cystatin C in acute kidney injury diagnosis: early biomarker or alternative to serum creatinine?. Pediatric Nephrology. 2015; 30:665-676.

Prowle, JR; Calzavacca, P; Licari, E; Ligabo, EV; Echeverri, JE; Bagshaw, SM; Haase-Fielitz, A; Haase, M; Ostland, V; Noiri, E; et al. Combination of biomarkers for diagnosis of acute kidney injury after cardiopulmonary bypass. Renal Failure. 2015; 37:408-416.

Bucholz, EM; Whitlock, RP; Zappitelli, M; Devarajan, P; Eikelboom, J; Garg, AX; Philbrook, HT; Devereaux, PJ; Krawczeski, CD; Kavsak, P; et al. Cardiac Biomarkers and Acute Kidney Injury After Cardiac Surgery. Pediatrics. 2015; 135:E945-E956.

Devarajan, P. Genomic and Proteomic Characterization of Acute Kidney Injury. Nephron. 2015; 131:85-91.