Devarajan Lab

MacLaughlin, HL; Pike, M; Selby, NM; Siew, E; Chinchilli, VM; Guide, A; Stewart, TG; Himmelfarb, J; Go, AS; Parikh, CR; et al. Body mass index and chronic kidney disease outcomes after acute kidney injury: a prospective matched cohort study. BMC Nephrology. 2021; 22.

Flannery, AH; Ortiz-Soriano, V; Li, X; Gianella, FG; Toto, RD; Moe, OW; Devarajan, P; Goldstein, SL; Neyra, JA. Serum renin and major adverse kidney events in critically ill patients: a multicenter prospective study. Critical Care. 2021; 25.

Elitok, S; Kuppe, H; Devarajan, P; Bellomo, R; Isermann, B; Westphal, S; Kube, J; Albert, C; Ernst, M; Kropf, S; et al. Urinary Neutrophil Gelatinase-Associated Lipocalin/Hepcidin-25 Ratio for Early Identification of Patients at Risk for Renal Replacement Therapy After Cardiac Surgery: A Substudy of the BICARBONATE Trial. Anesthesia and Analgesia. 2021; 133:1510-1519.

Elitok, S; Isermann, B; Westphal, S; Devarajan, P; Albert, C; Kuppe, H; Ernst, M; Bellomo, R; Haase, M; Haase-Fielitz, A. Urinary biomarkers to predict severe fluid overload after cardiac surgery: a pilot study. Biomarkers in Medicine. 2021; 15:1451-1464.

Cody, EM; Bennett, MR; Gulati, G; Ma, Q; Altaye, M; Devarajan, P; Brunner, HI. Successful Urine Multiplex Bead Assay to Measure Lupus Nephritis Activity. Kidney International Reports. 2021; 6:1949-1960.

Lebel, A; Chui, H; McMahon, KR; Lim, YJ; Macri, J; Wang, S; Devarajan, P; Blydt-Hansen, TD; Zappitelli, M; Urquhart, BL. Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer. Journal of Clinical Pharmacology. 2021; 61:871-880.

Stenvinkel, P; Chertow, GM; Devarajan, P; Levin, A; Andreoli, SP; Bangalore, S; Warady, BA. Chronic Inflammation in Chronic Kidney Disease Progression: Role of Nrf2. Kidney International Reports. 2021; 6:1775-1787.

Fredric, D; Greenberg, JH; Parikh, CR; Devarajan, P; Chui, H; Cockovski, V; Pizzi, M; Palijan, A; Hessey, E; Jia, Y; et al. 24-hour ambulatory blood pressure monitoring 9 years after pediatric cardiac surgery: a pilot and feasibility study. Pediatric Nephrology. 2021; 36:1533-1541.

Elitok, S; Devarajan, P; Bellomo, R; Isermann, B; Haase, M; Haase-Fielitz, A. NGAL/hepcidin-25 ratio and AKI subtypes in patients following cardiac surgery: a prospective observational study. Journal of Nephrology. 2021.

Standage, SW; Xu, S; Brown, L; Ma, Q; Koterba, A; Lahni, P; Devarajan, P; Kennedy, MA. NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. American Journal of Physiology - Renal Physiology. 2021; 320:F984-F1000.

Ikizler, TA; Parikh, CR; Himmelfarb, J; Chinchilli, VM; Liu, KD; Coca, SG; Garg, AX; Hsu, CY; Siew, ED; Wurfel, MM; et al. A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death. Kidney International. 2021; 99:456-465.

Benoit, SW; Kathman, T; Patel, J; Stegman, M; Cobb, C; Hoehn, J; Devarajan, P; Nehus, EJ. GFR Estimation After Cystatin C Reference Material Change. Kidney International Reports. 2021; 6:429-436.

Greenberg, JH; Parsons, M; Zappitelli, M; Jia, Y; Thiessen-Philbrook, HR; Devarajan, P; Everett, AD; Parikh, CR. Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery. Annals of Thoracic Surgery. 2021; 111:191-198.

Stone, HK; Parameswaran, S; Eapen, AA; Chen, X; Harley, JB; Devarajan, P; Weirauch, MT; Kottyan, L. Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk. Kidney International Reports. 2021; 6:187-195.

Albert, C; Zapf, A; Haase, M; Röver, C; Pickering, JW; Albert, A; Bellomo, R; Breidthardt, T; Camou, F; Chen, Z; et al. Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy: A Systematic Review and Meta-analysis. American Journal of Kidney Diseases. 2020; 76:826-841.e1.

Rudman-Melnick, V; Adam, M; Potter, A; Chokshi, SM; Ma, Q; Drake, KA; Schuh, MP; Matthew Kofron, J; Devarajan, P; Steven Potter, S. Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk. Journal of the American Society of Nephrology : JASN. 2020; 31:2793-2814.

Wang, X; Bhutani, G; Vaughan, LE; Enders, FT; Haskic, Z; Milliner, D; Lieske, JC; Assimos, D; Baum, M; Somers, M; et al. Urinary monocyte chemoattractant protein 1 associated with calcium oxalate crystallization in patients with primary hyperoxaluria. BMC Nephrology. 2020; 21.

Zappitelli, M; Parikh, CR; Kaufman, JS; Go, AS; Kimmel, PL; Hsu, CY; Coca, SG; Chinchilli, VM; Greenberg, JH; Moxey-Mims, MM; et al. Acute Kidney Injury and Risk of CKD and Hypertension after Pediatric Cardiac Surgery. Clinical journal of the American Society of Nephrology : CJASN. 2020; 15:1403-1412.

Benoit, SW; Ciccia, EA; Devarajan, P. Cystatin C as a biomarker of chronic kidney disease: latest developments. Expert Review of Molecular Diagnostics. 2020; 20:1019-1026.

Steubl, D; Buzkova, P; Garimella, PS; Ix, JH; Devarajan, P; Bennett, MR; Chaves, PH M; Shlipak, MG; Bansal, N; Sarnak, MJ. Association of serum uromodulin with mortality and cardiovascular disease in the elderly-the Cardiovascular Health Study. Nephrology Dialysis Transplantation. 2020; 35:1399-1405.

Roy, J; Devarajan, P. Acute Kidney Injury: Diagnosis and Management. Indian Journal of Pediatrics. 2020; 87:600-607.

Steubl, D; Buzkova, P; Ix, JH; Devarajan, P; Bennett, MR; Chaves, PH M; Shlipak, MG; Bansal, N; Sarnak, MJ; Garimella, PS. Association of serum and urinary uromodulin and their correlates in older adults-The Cardiovascular Health Study. Nephrology. 2020; 25:522-526.

Chui, H; Caldwell, J; Yordanova, M; Cockovski, V; Fredric, D; Harel-Sterling, M; Haasz, M; Al-Ismaili, Z; Pizzi, M; Ma, Q; et al. Tubular injury and cell-cycle arrest biomarkers to predict acute kidney injury in noncritically ill children receiving aminoglycosides. Biomarkers in Medicine. 2020; 14:879-894.

Devarajan, P. The Current State of the Art in Acute Kidney Injury. Frontiers in Pediatrics. 2020; 8.

Stark, JE; Opoka, AM; Mallela, J; Devarajan, P; Ma, Q; Levinsky, NC; Stringer, KF; Wong, HR; Alder, MN. Juvenile OLFM4-null mice are protected from sepsis. American Journal of Physiology - Renal Physiology. 2020; 318:F809-F816.

Hsu, C; Chinchilli, VM; Coca, S; Devarajan, P; Ghahramani, N; Go, AS; Hsu, RK; Ikizler, TA; Kaufman, J; Liu, KD; et al. Post-Acute Kidney Injury Proteinuria and Subsequent Kidney Disease Progression: The Assessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) Study. JAMA Internal Medicine. 2020; 180:402-410.

Steubl, D; Buzkova, P; Garimella, PS; Ix, JH; Devarajan, P; Bennett, MR; Chaves, PH M; Shlipak, MG; Bansal, N; Sarnak, MJ. Association of Serum Uromodulin With ESKD and Kidney Function Decline in the Elderly: The Cardiovascular Health Study. American Journal of Kidney Diseases. 2019; 74:501-509.

De Oliveira, BD; Xu, K; Shen, TH; Callahan, M; Kiryluk, K; D'Agati, VD; Tatonetti, NP; Barasch, J; Devarajan, P. Molecular nephrology: types of acute tubular injury. Nature Reviews Nephrology. 2019; 15:599-612.

Bowers, SL K; Davis-Rodriguez, S; Thomas, ZM; Rudomanova, V; Bacon, WC; Beiersdorfer, A; Ma, Q; Devarajan, P; Blaxall, BC. Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion. American Journal of Physiology - Renal Physiology. 2019; 316:F1293-F1298.

Schuh, MP; Bennett, MR; Lane, A; Jodele, S; Laskin, BL; Devarajan, P. Haptoglobin degradation product as a novel serum biomarker for hematopoietic stem cell transplant-associated thrombotic microangiopathy. Pediatric Nephrology. 2019; 34:865-871.

Aljaberi, N; Bennett, M; Brunner, HI; Devarajan, P. Proteomic profiling of urine: implications for lupus nephritis. Expert Review of Proteomics. 2019; 16:303-313.

Forster, CS; Haffey, WD; Bennett, M; Greis, KD; Deyarajan, P. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Children With Neurogenic Bladders. Biomarker Insights. 2019; 14.

Turnier, JL; Brunner, HI; Bennett, M; Aleed, A; Gulati, G; Haffey, WD; Thornton, S; Wagner, M; Devarajan, P; Witte, D; et al. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology. 2019; 58:321-330.

Carpenter, SL; Goldman, J; Sherman, AK; Selewski, DT; Kallash, M; Tran, CL; Seamon, M; Katsoufis, C; Ashoor, I; Hernandez, J; et al. Association of infections and venous thromboembolism in hospitalized children with nephrotic syndrome. Pediatric Nephrology. 2019; 34:261-267.

Brunner, HI; Gulati, G; Klein-Gitelman, MS; Rouster-Stevens, KA; Tucker, L; Ardoin, SP; Onel, KB; Mainville, R; Turnier, J; Aydin, PO A; et al. Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus. Pediatric Nephrology. 2019; 34:117-128.

Parameswaran, P; Devarajan, P. Cellular and Molecular Mechanisms of Acute Kidney Injury. Critical Care Nephrology: Third Edition. 2019.

Parameswaran, P; Devarajan, P. Chapter 198 Cellular and Molecular Mechanisms of Acute Kidney Injury. Critical Care Nephrology. 2019.

Chihanga, T; Ruby, HN; Ma, Q; Bashir, S; Devarajan, P; Kennedy, MA. NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury. American Journal of Physiology - Renal Physiology. 2018; 315:F1159-F1173.

Albert, C; Albert, A; Bellomo, R; Kropf, S; Devarajan, P; Westphal, S; Baraki, H; Kutschka, I; Butter, C; Haase, M; et al. Urinary neutrophil gelatinase-associated lipocalin-guided risk assessment for major adverse kidney events after open-heart surgery. Biomarkers in Medicine. 2018; 12:975-985.

Lang, J; Katz, R; Ix, JH; Gutierrez, OM; Peralta, CA; Parikh, CR; Satterfield, S; Petrovic, S; Devarajan, P; Bennett, M; et al. Association of serum albumin levels with kidney function decline and incident chronic kidney disease in elders. Nephrology Dialysis Transplantation. 2018; 33:986-992.

Greenberg, JH; Devarajan, P; Thiessen-Philbrook, HR; Krawczeski, C; Parikh, CR; Zappitelli, M; Consortium, TR I B E-A K. Kidney injury biomarkers 5 years after AKI due to pediatric cardiac surgery. Pediatric Nephrology. 2018; 33:1069-1077.

Benoit, SW; Devarajan, P. Acute kidney injury: emerging pharmacotherapies in current clinical trials. Pediatric Nephrology. 2018; 33:779-787.

Greenberg, JH; Zappitelli, M; Jia, Y; Thiessen-Philbrook, HR; de Fontnouvelle, CA; Wilson, FP; Coca, S; Devarajan, P; Parikh, CR. Biomarkers of AKI Progression after Pediatric Cardiac Surgery. Journal of the American Society of Nephrology : JASN. 2018; 29:1549-1556.

Bennett, MR; Devarajan, P. The future role of proteomics in the understanding of acute kidney injury. Expert Review of Proteomics. 2018; 15:191-192.

Bennett, MR; Pyles, O; Ma, Q; Devarajan, P. Preoperative levels of urinary uromodulin predict acute kidney injury after pediatric cardiopulmonary bypass surgery. Pediatric Nephrology. 2018; 33:521-526.

Chihanga, T; Ma, Q; Nicholson, JD; Ruby, HN; Edelmann, RE; Devarajan, P; Kennedy, MA. NMR spectroscopy and electron microscopy identification of metabolic and ultrastructural changes to the kidney following ischemia-reperfusion injury. American Journal of Physiology - Renal Physiology. 2018; 314:F154-F166.

Goldstein, BH; Goldstein, SL; Devarajan, P; Zafar, F; Kwiatkowski, DM; Marino, BS; Morales, DL S; Krawczeski, CD; Cooper, DS. First-stage palliation strategy for univentricular heart disease may impact risk for acute kidney injury. Cardiology in the Young. 2018; 28:93-100.

Dong, L; Ma, Q; Bennett, M; Devarajan, P. Urinary biomarkers of cell cycle arrest are delayed predictors of acute kidney injury after pediatric cardiopulmonary bypass. Pediatric Nephrology. 2017; 32:2351-2360.

de Fontnouvelle, CA; Greenberg, JH; Thiessen-Philbrook, HR; Zappitelli, M; Roth, J; Kerr, KF; Devarajan, P; Shlipak, M; Coca, S; Parikh, CR; et al. Interleukin-8 and Tumor Necrosis Factor Predict Acute Kidney Injury After Pediatric Cardiac Surgery. Annals of Thoracic Surgery. 2017; 104:2072-2079.

Jr, VC D; Goldstein, SL; Devarajan, P; Basu, RK. Impact of Near Real-Time Urine Neutrophil Gelatinase-Associated Lipocalin Assessment on Clinical Practice. Kidney International Reports. 2017; 2:1243-1249.

Bennett, MR; Ma, Q; Ying, J; Devarajan, P; Brunner, H. Effects of age and gender on reference levels of biomarkers comprising the pediatric Renal Activity Index for Lupus Nephritis (p-RAIL). Pediatric Rheumatology. 2017; 15.

Sterling, M; Al-Ismaili, Z; McMahon, KR; Piccioni, M; Pizzi, M; Mottes, T; Lands, LC; Abish, S; Fleming, AJ; Bennett, MR; et al. Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy. Pediatric Blood and Cancer. 2017; 64.

Nehus, E; Kaddourah, A; Bennett, M; Pyles, O; Devarajan, P. Subclinical Kidney Injury in Children Receiving Nonsteroidal Anti-Inflammatory Drugs After Cardiac Surgery. Journal of Pediatrics. 2017; 189:175-180.

Quinn, CT; Saraf, SL; Gordeuk, VR; Fitzhugh, CD; Creary, SE; Bodas, P; George, A; Raj, AB; Nero, AC; Terrell, CE; et al. Losartan for the nephropathy of sickle cell anemia: A phase-2, multicenter trial. American Journal of Hematology. 2017; 92:E520-E528.

Pleasant, L; Ma, Q; Devarajan, M; Parameswaran, P; Drake, K; Siroky, B; Shay-Winkler, K; Robbins, J; Devarajan, P. Increased susceptibility to structural acute kidney injury in a mouse model of presymptomatic cardiomyopathy. American Journal of Physiology - Renal Physiology. 2017; 313:F699-F705.

Devarajan, P. Kidney Attack: Is NGAL Set to Take the Stage with Troponins?. Cardio-Nephrology. 2017.

Gulati, G; Bennett, MR; Abulaban, K; Song, H; Zhang, X; Ma, Q; Brodsky, SV; Nadasdy, T; Haffner, C; Wiley, K; et al. Prospective validation of a novel renal activity index of lupus nephritis. Lupus. 2017; 26:927-936.

Brunner, HI; Bennett, MR; Gulati, G; Abulaban, K; Klein-Gitelman, MS; Ardoin, SP; Tucker, LB; Rouster-Stevens, KA; Witte, D; Ying, J; et al. Urine Biomarkers to Predict Response to Lupus Nephritis Therapy in Children and Young Adults. Journal of Rheumatology. 2017; 44:1239-1248.

Garimella, PS; Bartz, TM; Ix, JH; Chonchol, M; Shlipak, MG; Devarajan, P; Bennett, MR; Sarnak, MJ. Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study. American Journal of Kidney Diseases. 2017; 69:744-751.

Palermo, J; Dart, AB; De Mello, A; Devarajan, P; Gottesman, R; Guerra, GG; Hansen, G; Joffe, AR; Mammen, C; Majesic, N; et al. Biomarkers for Early Acute Kidney Injury Diagnosis and Severity Prediction: A Pilot Multicenter Canadian Study of Children Admitted to the ICU. Pediatric Critical Care Medicine. 2017; 18:e235-e244.

Garimella, PS; Katz, R; Ix, JH; Fried, LF; Kritchevsky, SB; Devarajan, P; Bennett, MR; Parikh, CR; Shlipak, MG; Harris, TB; et al. Association of urinary uromodulin with kidney function decline and mortality: the health ABC study
. Clinical Nephrology. 2017; 87:278-286.

Ciccia, E; Devarajan, P. Pediatric acute kidney injury: prevalence, impact and management challenges. International Journal of Nephrology and Renovascular Disease. 2017; 10:77-84.

Bennett, MR; Pleasant, L; Haffner, C; Ma, Q; Haffey, WD; Ying, J; Wagner, M; Greis, KD; Devarajan, P. A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome. Biomarker Insights. 2017; 12.

Forster, CS; Devarajan, P. Neutrophil gelatinase-associated lipocalin: utility in urologic conditions. Pediatric Nephrology. 2017; 32:377-381.

Devarajan, P. Acute kidney injury: Acute kidney injury: still misunderstood and misdiagnosed. Nature Reviews Nephrology. 2017; 13:137-138.

Devarajan, P. Acute Kidney Injury: Prevention and Diagnosis. Pediatric Kidney Disease. 2017.