Devarajan Lab

Publications

Fuhrman, DY; Stanski, NL; Krawczeski, CD; Greenberg, JH; Arikan, AA A; Basu, RK; Goldstein, SL; Gist, KM. A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children: a report from the 26th Acute Disease Quality Initiative (ADQI) conference. Pediatric Nephrology. 2024; 39:929-939.

Starr, MC; Barreto, E; Charlton, J; Vega, M; Brophy, PD; Ray Bignall, ON; Sutherland, SM; Menon, S; Devarajan, P; Akcan Arikan, A; et al. Advances in pediatric acute kidney injury pathobiology: a report from the 26th Acute Disease Quality Initiative (ADQI) conference. Pediatric Nephrology. 2024; 39:941-953.

Mottes, T; Menon, S; Conroy, A; Jetton, J; Dolan, K; Arikan, AA; Basu, RK; Goldstein, SL; Symons, JM. Pediatric AKI in the real world: changing outcomes through education and advocacy-a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference. Pediatric Nephrology. 2024; 39:1005-1014.

Wong Vega, M; Starr, MC; Brophy, PD; Devarajan, P; Soranno, DE; Akcan-Arikan, A; Basu, R; Goldstein, SL; Charlton, JR; Barreto, E. Advances in pediatric acute kidney injury pharmacology and nutrition: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference. Pediatric Nephrology. 2024; 39:981-992.

Sutherland, SM; Alobaidi, R; Gorga, SM; Iyengar, A; Morgan, C; Heydari, E; Arikan, AA A; Basu, RK; Goldstein, SL; Zappitelli, M. Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference. Pediatric Nephrology. 2024; 39:919-928.

Selewski, DT; Barhight, MF; Bjornstad, EC; Ricci, Z; de Sousa Tavares, M; Akcan-Arikan, A; Goldstein, SL; Basu, R; Bagshaw, SM. Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference. Pediatric Nephrology. 2024; 39:955-979.

Neumayr, TM; Bayrakci, B; Chanchlani, R; Deep, A; Morgan, J; Arikan, AA; Basu, RK; Goldstein, SL; Askenazi, DJ. Programs and processes for advancing pediatric acute kidney support therapy in hospitalized and critically ill children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference. Pediatric Nephrology. 2024; 39:993-1004.

Chui, H; McMahon, KR; Rassekh, SR; Schultz, KR; Blydt-Hansen, TD; Mammen, C; Pinsk, M; Cuvelier, GD E; Carleton, BC; Tsuyuki, RT; et al. Urinary TIMP-2*IGFBP-7 to diagnose acute kidney injury in children receiving cisplatin. Pediatric Nephrology. 2024; 39:269-282.

Wang, CS; Glenn, DA; Helmuth, M; Smith, AR; Bomback, AS; Canetta, PA; Coppock, GM; Khalid, M; Tuttle, KR; Bou-Matar, R; et al. Association of COVID-19 Versus COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study. American Journal of Kidney Diseases. 2024; 83:37-46.

We, Y; Su, E; Xu, L; Menez, S; Moledina, DG; Obeid, W; Palevsky, PM; Mansour, SG; Devarajan, P; Cantley, LG; et al. Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury. Science Translational Medicine. 2023; 15:eade7287.

Rheault, MN; McLaughlin, HM; Mitchell, A; Blake, LE; Devarajan, P; Warady, BA; Gibson, KL; Lieberman, KV. COL4A gene variants are common in children with hematuria and a family history of kidney disease. Pediatric Nephrology. 2023; 38:3625-3633.

Stone, HK; Huang, B; Chen, C; Ma, Q; Bennett, MR; Devarajan, P. External Validation of a Urinary Biomarker Risk Score for the Prediction of Steroid Responsiveness in Adults With Nephrotic Syndrome. Kidney International Reports. 2023; 8:2458-2468.

Hasson, DC; Zhang, B; Krallman, K; Rose, JE; Kempton, KM; Steele, P; Devarajan, P; Goldstein, SL; Alder, MN. Acute kidney injury biomarker olfactomedin 4 predicts furosemide responsiveness. Pediatric Nephrology. 2023; 38:3153-3161.

Cody, EM; Wenderfer, SE; Sullivan, KE; Kim, AH J; Figg, W; Ghumman, H; Qiu, T; Huang, B; Devarajan, P; Brunner, HI. Urine biomarker score captures response to induction therapy with lupus nephritis. Pediatric Nephrology. 2023; 38:2679-2688.

de Fontnouvelle, C; Zappitelli, M; Thiessen-Philbrook, HR; Jia, Y; Kimmel, PL; Kaufman, JS; Devarajan, P; Parikh, CR; Greenberg, JH. Biomarkers of eGFR decline after cardiac surgery in children: findings from the ASSESS-AKI study. Pediatric Nephrology. 2023; 38:2851-2860.

Chen, DP; Helmuth, ME; Smith, AR; Canetta, PA; Ayoub, I; Mucha, K; Kallash, M; Kopp, JB; Gbadegesin, R; Gillespie, BW; et al. Age of Onset and Disease Course in Biopsy-Proven Minimal Change Disease: An Analysis From the Cure Glomerulonephropathy Network. American Journal of Kidney Diseases. 2023; 81:695-706.e1.

Devarajan, P. Pathogenesis of intrinsic acute kidney injury. Current Opinion in Pediatrics. 2023; 35:234-238.

DeFoor, W; Lee, J; Edward, N; Schulte, M; Huesman, S; Libs, A; Devarajan, P. MP10-02 DIETARY INTERVENTION IN ENTERIC HYPEROXALURIA. Investigative Urology. 2023; 209:e114.

Devarajan, P. Acute Kidney Injury: Pathophysiology, Diagnosis and Prevention. Pediatric Kidney Disease. : Springer Nature; Springer Nature; 2023.

DeFoor, W; Nehus, E; Schulte, M; Huesman, S; Libs, A; Niehaus, R; Devarajan, P. Enteral nutrition and the risk of nephrolithiasis in complex pediatric patients. Journal of Pediatric Urology. 2022; 18:743.e1-743.e6.

Kharnaf, M; Hogue, S; Wilkes, Z; Reagor, JA; Leino, DG; Gourley, B; Rosenfeldt, L; Ma, Q; Devarajan, P; Palumbo, JS; et al. A Murine Model of Veno-Arterial Extracorporeal Membrane Oxygenation. ASAIO Journal. 2022; 68:e243-e250.

Goldstein, SL; Akcan-Arikan, A; Alobaidi, R; Askenazi, DJ; Bagshaw, SM; Barhight, M; Barreto, E; Bayrakci, B; Bignall, ON R; Bjornstad, E; et al. Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement. JAMA Network Open. 2022; 5:e2229442.

Hasson, DC; Watanabe-Chailland, M; Romick-Rosendale, L; Koterba, A; Miner, DS; Lahni, P; Ma, Q; Goldstein, SL; Devarajan, P; Standage, SW. Choline supplementation attenuates experimental sepsis-associated acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2022; 323:F255-F271.

Hasson, DC; Krallman, K; VanDenHeuvel, K; Menon, S; Piraino, G; Devarajan, P; Goldstein, SL; Alder, M. Olfactomedin 4 as a novel loop of Henle-specific acute kidney injury biomarker. Physiological Reports. 2022; 10:e15453.

Cody, EM; Rose, JE; Huang, B; Qiu, T; Brunner, HI; Devarajan, P. Stability of novel urinary biomarkers used for lupus nephritis. Frontiers in Pediatrics. 2022; 10:974049.

Pode-Shakked, N; Devarajan, P. Human Stem Cell and Organoid Models to Advance Acute Kidney Injury Diagnostics and Therapeutics. International Journal of Molecular Sciences. 2022; 23:7211.

Lieberman, KV; Chang, AR; Block, GA; Robinson, K; Bristow, SL; Morales, A; Mitchell, A; McCalley, S; McKay, J; Pollak, MR; et al. The KIDNEYCODE Program: Diagnostic Yield and Clinical Features of Individuals with CKD. 2022; 3:900-909.

Odum, JD; Standage, S; Alder, M; Zingarelli, B; Devarajan, P; Wong, HR. Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies. Shock. 2022; 57:687-693.

Dillman, JR; Benoit, SW; Gandhi, DB; Trout, AT; Tkach, JA; VandenHeuvel, K; Devarajan, P. Multiparametric quantitative renal MRI in children and young adults: comparison between healthy individuals and patients with chronic kidney disease. Abdominal Radiology. 2022; 47:1840-1852.

Aljaberi, N; Wenderfer, SE; Mathur, A; Qiu, T; Jose, S; Merritt, A; Rose, J; Devarajan, P; Huang, B; Brunner, H. Clinical measurement of lupus nephritis activity is inferior to biomarker-based activity assessment using the renal activity index for lupus nephritis in childhood-onset systemic lupus erythematosus. Lupus Science and Medicine. 2022; 9:e000631.

Devarajan, P; Chertow, GM; Susztak, K; Levin, A; Agarwal, R; Stenvinkel, P; Chapman, AB; Warady, BA. Emerging Role of Clinical Genetics in CKD. Kidney Medicine. 2022; 4:100435.

Elitok, S; Devarajan, P; Bellomo, R; Isermann, B; Haase, M; Haase-Fielitz, A. NGAL/hepcidin-25 ratio and AKI subtypes in patients following cardiac surgery: a prospective observational study. Journal of Nephrology. 2022; 35:597-605.

Chalhoub, NE; Wenderfer, SE; Levy, DM; Rouster-Stevens, K; Aggarwal, A; Savani, SI; Ruth, NM; Arkachaisri, T; Qiu, T; Merritt, A; et al. International Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis. Arthritis and Rheumatology. 2022; 74:263-273.

Mcmahon, KR; Chui, H; Rassekh, SR; Schultz, KR; Blydt-Hansen, TD; Mammen, C; Pinsk, M; Cuvelier, GD E; Carleton, BC; Tsuyuki, RT; et al. Urine Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 to Detect Pediatric Cisplatin-Associated Acute Kidney Injury. 2022; 3:37-50.

Jeyaraju, M; McCurdy, MT; Levine, AR; Devarajan, P; Mazzeffi, MA; Mullins, KE; Reif, M; Yim, DN; Parrino, C; Lankford, AS; et al. Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients. Critical Care Medicine. 2022; 50:50-60.

MacLaughlin, HL; Pike, M; Selby, NM; Siew, E; Chinchilli, VM; Guide, A; Stewart, TG; Himmelfarb, J; Go, AS; Parikh, CR; et al. Body mass index and chronic kidney disease outcomes after acute kidney injury: a prospective matched cohort study. BMC Nephrology. 2021; 22:200.

Flannery, AH; Ortiz-Soriano, V; Li, X; Gianella, FG; Toto, RD; Moe, OW; Devarajan, P; Goldstein, SL; Neyra, JA. Serum renin and major adverse kidney events in critically ill patients: a multicenter prospective study. Critical Care (UK). 2021; 25:294.

Elitok, S; Kuppe, H; Devarajan, P; Bellomo, R; Isermann, B; Westphal, S; Kube, J; Albert, C; Ernst, M; Kropf, S; et al. Urinary Neutrophil Gelatinase-Associated Lipocalin/Hepcidin-25 Ratio for Early Identification of Patients at Risk for Renal Replacement Therapy After Cardiac Surgery: A Substudy of the BICARBONATE Trial. Anesthesia and Analgesia. 2021; 133:1510-1519.

Elitok, S; Isermann, B; Westphal, S; Devarajan, P; Albert, C; Kuppe, H; Ernst, M; Bellomo, R; Haase, M; Haase-Fielitz, A. Urinary biomarkers to predict severe fluid overload after cardiac surgery: a pilot study. Biomarkers in medicine. 2021; 15:1451-1464.

Stenvinkel, P; Chertow, GM; Devarajan, P; Levin, A; Andreoli, SP; Bangalore, S; Warady, BA. Chronic Inflammation in Chronic Kidney Disease Progression: Role of Nrf2. Kidney International Reports. 2021; 6:1775-1787.

Lebel, A; Chui, H; McMahon, KR; Lim, YJ; Macri, J; Wang, S; Devarajan, P; Blydt-Hansen, TD; Zappitelli, M; Urquhart, BL. Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer. Journal of Clinical Pharmacology. 2021; 61:871-880.

Cody, EM; Bennett, MR; Gulati, G; Ma, Q; Altaye, M; Devarajan, P; Brunner, HI. Successful Urine Multiplex Bead Assay to Measure Lupus Nephritis Activity. Kidney International Reports. 2021; 6:1949-1960.

Fredric, D; Greenberg, JH; Parikh, CR; Devarajan, P; Chui, H; Cockovski, V; Pizzi, M; Palijan, A; Hessey, E; Jia, Y; et al. 24-hour ambulatory blood pressure monitoring 9 years after pediatric cardiac surgery: a pilot and feasibility study. Pediatric Nephrology. 2021; 36:1533-1541.

Standage, SW; Xu, S; Brown, L; Ma, Q; Koterba, A; Lahni, P; Devarajan, P; Kennedy, MA. NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2021; 320:F984-F1000.

Benoit, SW; Kathman, T; Patel, J; Stegman, M; Cobb, C; Hoehn, J; Devarajan, P; Nehus, EJ. GFR Estimation After Cystatin C Reference Material Change. Kidney International Reports. 2021; 6:429-436.

Ikizler, TA; Parikh, CR; Himmelfarb, J; Chinchilli, VM; Liu, KD; Coca, SG; Garg, AX; Hsu, CY; Siew, ED; Wurfel, MM; et al. A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death. Kidney International. 2021; 99:456-465.

Stone, HK; Parameswaran, S; Eapen, AA; Chen, X; Harley, JB; Devarajan, P; Weirauch, MT; Kottyan, L. Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk. Kidney International Reports. 2021; 6:187-195.

Greenberg, JH; Parsons, M; Zappitelli, M; Jia, Y; Thiessen-Philbrook, HR; Devarajan, P; Everett, AD; Parikh, CR. Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery. Annals of Thoracic Surgery. 2021; 111:191-198.

Rudman-Melnick, V; Adam, M; Potter, A; Chokshi, SM; Ma, Q; Drake, KA; Schuh, MP; Matthew Kofron, J; Devarajan, P; Steven Potter, S. Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk. Journal of the American Society of Nephrology : JASN. 2020; 31:2793-2814.

Albert, C; Zapf, A; Haase, M; Röver, C; Pickering, JW; Albert, A; Bellomo, R; Breidthardt, T; Camou, F; Chen, Z; et al. Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy: A Systematic Review and Meta-analysis. American Journal of Kidney Diseases. 2020; 76:826-841.e1.

Wang, X; Bhutani, G; Vaughan, LE; Enders, FT; Haskic, Z; Milliner, D; Lieske, JC; Assimos, D; Baum, M; Somers, M; et al. Urinary monocyte chemoattractant protein 1 associated with calcium oxalate crystallization in patients with primary hyperoxaluria. BMC Nephrology. 2020; 21:133.

Nunes, S; Brown, J; Parikh, CR; Greenberg, JH; Devarajan, P; Philbrook, HT; Pizzi, M; Palijan, A; Zappitelli, M. The association of acute kidney injury with hospital readmission and death after pediatric cardiac surgery. JTCVS Open. 2020; 4:70-85.

Zappitelli, M; Parikh, CR; Kaufman, JS; Go, AS; Kimmel, PL; Hsu, CY; Coca, SG; Chinchilli, VM; Greenberg, JH; Moxey-Mims, MM; et al. Acute Kidney Injury and Risk of CKD and Hypertension after Pediatric Cardiac Surgery. Clinical journal of the American Society of Nephrology : CJASN. 2020; 15:1403-1412.

Benoit, SW; Ciccia, EA; Devarajan, P. Cystatin C as a biomarker of chronic kidney disease: latest developments. Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare. 2020; 20:1019-1026.

Roy, J; Devarajan, P. Acute Kidney Injury: Diagnosis and Management. The Indian Journal of Pediatrics. 2020; 87:600-607.

Steubl, D; Buzkova, P; Garimella, PS; Ix, JH; Devarajan, P; Bennett, MR; Chaves, PH M; Shlipak, MG; Bansal, N; Sarnak, MJ. Association of serum uromodulin with mortality and cardiovascular disease in the elderly-the Cardiovascular Health Study. Nephrology Dialysis Transplantation. 2020; 35:1399-1405.

Chui, H; Caldwell, J; Yordanova, M; Cockovski, V; Fredric, D; Harel-Sterling, M; Haasz, M; Al-Ismaili, Z; Pizzi, M; Ma, Q; et al. Tubular injury and cell-cycle arrest biomarkers to predict acute kidney injury in noncritically ill children receiving aminoglycosides. Biomarkers in medicine. 2020; 14:879-894.

Steubl, D; Buzkova, P; Ix, JH; Devarajan, P; Bennett, MR; Chaves, PH M; Shlipak, MG; Bansal, N; Sarnak, MJ; Garimella, PS. Association of serum and urinary uromodulin and their correlates in older adults-The Cardiovascular Health Study. Nephrology. 2020; 25:522-526.

Devarajan, P; Block, G; Gibson, K; McKay, J; Meyer, C; Robinson, K; Warady, B; Chang, A. P0066KIDNEYCODE: A GENETIC TESTING PROGRAM FOR PATIENTS WITH CHRONIC KIDNEY DISEASE. Nephrology Dialysis Transplantation. 2020; 35:gfaa142.p0066.

Devarajan, P. The Current State of the Art in Acute Kidney Injury. Frontiers in Pediatrics. 2020; 8:70.

Hsu, C; Chinchilli, VM; Coca, S; Devarajan, P; Ghahramani, N; Go, AS; Hsu, RK; Ikizler, TA; Kaufman, J; Liu, KD; et al. Post-Acute Kidney Injury Proteinuria and Subsequent Kidney Disease Progression: The Assessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) Study. JAMA Internal Medicine. 2020; 180:402-410.

Stark, JE; Opoka, AM; Mallela, J; Devarajan, P; Ma, Q; Levinsky, NC; Stringer, KF; Wong, HR; Alder, MN. Juvenile OLFM4-null mice are protected from sepsis. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2020; 318:F809-F816.