Pathology

Publications

Abla, O; Picarsic, J. Histiocytic tumors of the central nervous system. In: Batchelor T; Weller M, Ed. Oxford Textbook of Neuro-Oncology. : Oxford University Press (OUP); Oxford University Press (OUP); 2025.

Agarwal, P; Sampson, A; Hueneman, K; Choi, K; Jakobsen, NA; Uible, E; Ishikawa, C; Yeung, J; Bolanos, L; Zhao, X; Galloway-Pena, J; Byrd, JC; Vyas, P; Starczynowski, DT. Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1. Nature. 2025; 642:201-211.

Ahmed, F; Zhao, X; Beres, R; Garlapally, V; Mouzaki, M; Setchell, KD; Husain, SZ; Abu-El-Haija, M. Sa1442: LIPIDOMIC AND METABOLOMIC INSIGHTS INTO PEDIATRIC CHRONIC PANCREATITIS: DECIPHERING THE METABOLIC LANDSCAPE. Gastroenterology. 2025; 169:s-471.

Ali, R; Li, H; Zhang, H; Pan, W; Reeder, SB; Harris, D; Masch, W; Aslam, A; Shanbhogue, K; Bernieh, A; Ranganathan, S; Parikh, N; Dillman, JR; He, L. Multi-site, multi-vendor development and validation of a deep learning model for liver stiffness prediction using abdominal biparametric MRI. European Radiology. 2025; 35:4362-4373.

Bove, KE; Lopez-Nunez, O; Bedrnicek, J; Huang, A; Freestone, D; Birge, N; Kumar, S. A Case of MIRAGE Syndrome with SAMD9 Mutation and Refractory Infantile Diarrhea: Endoscopic Biopsy Evaluation via Light and Electron Microscopy. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2025; 28:111-116.

Bullard Elias, D; Paisley, A; Betancur, D; Wallace, C; Wikenheiser-Brokamp, K; Hysinger, E; Burg, G. Transbronchial Cryobiopsy for Diffuse Lung Disease: A Case Series From a Single Pediatric Center. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a4484.

Cantrell, R; Alex Feldman, H; Rosenfeldt, L; Ali, A; Gourley, B; Sprague, C; Leino, D; Crosby, J; Revenko, A; Monia, B; Waggoner, SN; Palumbo, JS. Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice. JCI insight. 2025; 10:e181063.

Chen, D; Lu, S; Huang, K; Pearson, JD; Pacal, M; Peidis, P; McCurdy, S; Yu, T; Sangwan, M; Nguyen, A; Barbacid, M; Akeno, N; Wikenheiser-Brokamp, KA; Bremner, R. Cell cycle duration determines oncogenic transformation capacity. Nature. 2025; 641:1309-1318.

Chen, K; Wang, H; Ma, B; Knapp, J; Henchy, C; Lu, J; Stevens, T; Ranganathan, S; Prochownik, EV. Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis. The American journal of pathology. 2025; 195:982-994.

Collins, MH; Rothenberg, ME; Dellon, ES; Bredenoord, AJ; Hirano, I; Leung, J; Sun, X; Glotfelty, L; Shabbir, A. Dupilumab Improves Histopathologic Features in Patients With Eosinophilic Esophagitis: LIBERTY EoE TREET Study Results. Gastro Hep Advances. 2025; 4:100646.

Coorens, TH H; Guillaumet-Adkins, A; Kovner, R; Linn, RL; Roberts, VH J; Sule, A; Van Hoose, PM; Zou, S; Ramos, E; Price, A; Salehi, A; Roberts, R; Rasool, I; Rossi, C. The human and non-human primate developmental GTEx projects. Nature. 2025; 637:557-564.

Courtney, R; Dahlinghaus, E; Omoloja, A; Boyd, JT; Smith, M; Biederman, L; Ndengabaganizi, I; Robie, DK; Al Dughiem, A. A Benign Renal Tumor With Serious Consequences: A Case Report of Juxtaglomerular Cell Tumor and Chronic Renal Disease in a Teenager. Editor, Scaramuzza A. Case Reports in Pediatrics. 2025; 2025:9318115.

Dellon, ES; Collins, MH; Bredenoord, AJ; Philpott, H; Biedermann, L; Dulcine, M; Nguyen-Cleary, T; Su, C; Yu, J; Tan, H; Wang, W; Clax, P; Woolcott, JC; Hirano, I. Etrasimod as a treatment for eosinophilic oesophagitis (VOYAGE): a double-blind, placebo-controlled, randomised, phase 2 trial. The Lancet Gastroenterology and Hepatology. 2025; 10:622-633.

Dillman, JR; Tkach, JA; Fletcher, JG; Bruining, DH; Lu, A; Kugathasan, S; Alazraki, AL; Knight-Scott, J; Stidham, RW; Adler, J; Anton, CG; Imbus, RA; Dudley, JA; Denson, LA. Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease. Inflammatory Bowel Diseases. 2025; 31:1380-1391.

Fragneau, R; Fraitag, S; Kemps, PG; Hélias-Rodzewicz, Z; Roy, S; Bonsang, B; Bartlett, AL; Dhar, S; Jankofsky, M; Zlocha, J; Donadieu, J; Borkhardt, A; Picarsic, JL; Emile, JF. NTRK1-rearranged histiocytosis: clinicopathologic and molecular features. Blood Advances. 2025; 9:3617-3628.

Franciosi, AN; Gupta, N; Murphy, DJ; Wikenheiser-Brokamp, KA; McCarthy, C. Diffuse Cystic Lung Disease: A Clinical Guide to Recognition and Management. Chest. 2025; 167:529-547.

Galluzzo Mutti, L; Picarsic, J. Updates on Langerhans cell histiocytosis and other histiocytosis in children: invited review-challenges and novelties in paediatric tumours. Virchows Archiv: an international journal of pathology. 2025; 486:189-204.

Galluzzo Mutti, ML; Picarsic, J. Pediatric Pathology: Emerging Entities, Current Trends, and Comprehensive Updates, "Histiocytosis ". Surgical Pathology Clinics. 2025; 18:341-358.

Gautam, M; Jahagirdar, V; Mahadevia, H; Sanders, K; Campbell, JP; Sylvestre, PB; Chhabra, R; Clarkston, W; Jonnalagadda, SS. Double Whammy: A Case Report of Immune Checkpoint Inhibitor Colitis and Concomitant Cytomegalovirus Colitis in a Patient on Nivolumab. ACG Case Reports Journal. 2025; 12:e01569.

Gilene, S; Knapke, S; Leino, D; Roy, S; Raskin, S. A novel POT1-TPD presentation: A germline pathogenic POT1 variant discovered in a patient with newly diagnosed posterior fossa ependymoma. Cancer genetics. 2025; 292-293:38-43.

Glenn, DA; Carver, AW; Helmuth, ME; Smith, AR; Lafayette, RA; Ravipati, P; Oliverio, AL; Rizk, DV; Novak, J; Lugani, F; Bou-Matar, R; Wadhwani, S; Mariani, LH; Khalid, M. Proteinuria Trajectory and Disease Progression in Children and Adults with IgA Nephropathy/Vasculitis. Clinical journal of the American Society of Nephrology : CJASN. 2025; 20:978-992.

Gulati, N; Picarsic, J. IDCH: is it now determined?. Blood Advances. 2025; 9:496-498.

Hall, AD; Whitehurst, DA; Mortensen, JE; Prus, K; Staat, MA; Schlaudecker, EP; Prasanphanich, NS. Polymerase Chain Reaction Fails to Detect Mixed Malaria Infections in Siblings from Ethiopia. Journal of Infection and Chemotherapy. 2025; 31:102777.

Hartmann, JP; Nymand, SB; Hartmeyer, HL; Andersen, AB; Mohammad, M; Durrer, CG; Rasmussen, IE; Ryrsø, CK; Thomsen, RS; Hansen, SL; Christensen, RH; Iepsen, UW; Mortensen, J; Berg, RM G. Pulmonary adaptations to 12 wk of supervised high intensity interval training in COPD: a nonrandomized controlled pilot study. Journal of applied physiology (Bethesda, Md. : 1985). 2025; 138:1543-1559.

Hirano, I; Collins, MH; Katzka, DA; Mukkada, VA; Falk, GW; Terreri, B; Boules, M; Zhang, W; Desai, NK; Dellon, ES. Effect of Esophageal Dilation History on Efficacy Outcomes in Patients With Eosinophilic Esophagitis Receiving Budesonide Oral Suspension. The American Journal of Gastroenterology (Elsevier). 2025; 120:1502-1510.

Hite, CM; Varnell, CD; VandenHeuvel, KA; Woodle, ES; Barrett, WL; Hooper, DK. Local Graft Irradiation to Treat Refractory Acute Rejection in Pediatric and Young Adult Kidney Transplant Patients: A Case Series and Review of the Literature. Pediatric Transplantation. 2025; 29:e70132.

Huang, FS; Brady, RC; Mortensen, JE. Bacterial Meningitis—Fever, Headache, and A Stiff Neck … Looking Pretty Sick. Introduction to Clinical Infectious Diseases. : Springer Nature; Springer Nature; 2025.

Hutchinson, JC; Picarsic, J; McGenity, C; Treanor, D; Williams, B; Sebire, NJ. Whole Slide Imaging, Artificial Intelligence, and Machine Learning in Pediatric and Perinatal Pathology: Current Status and Future Directions. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2025; 28:91-98.

Kim, H; Yi, S; Liyanage, P; Zhao, S; Wikenheiser-Brokamp, KA; McMillin, L; Xu, Y; Kitzmiller, JA; Whitsett, JA; Naren, AP; Mun, KS. Development of a 3D bioengineered human lung submucosal gland ductal airway model to study mucociliary clearance in vitro. 2025; 1:100013.

Kliewer, KL; Abonia, JP; Aceves, SS; Atkins, D; Bonis, PA; Capocelli, KE; Chehade, M; Collins, MH; Dellon, ES; Fei, L; Sun, Q; Wechsler, JB; Yang, GY; Rothenberg, ME. One-food versus 4-food elimination diet for pediatric eosinophilic esophagitis: A multisite randomized trial. Journal of Allergy and Clinical Immunology. 2025; 155:520-532.

Koo, J; Cooper, R; Edwards, SL; Lane, A; Loveless, SK; Strecker, L; Lake, KE; Myers, KC; Towe, C; Patti, J; Li, M; Goldfarb, SB; Woods, JC; Davies, SM. High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study. Pediatric Blood and Cancer. 2025; e31916.

Li, J; Bai, J; Pham, VT; Hashimoto, M; Sezaki, M; Shi, Q; Jin, Q; He, C; Armstrong, A; Li, T; Luan, Y; Zeng, H; Andreassen, PR; Huang, G. Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells. The Journal of Clinical Investigation. 2025; 135:e184069.

Lin, H; Batajoo, A; Peckham-Gregory, E; Zinn, D; Eckstein, OS; El-Mallawany, NK; Gulati, N; Prudowsky, ZD; Scull, B; Velazquez, J; Man, TK; McClain, KL; Picarsic, J; Allen, CE. BRAF V600E-positive mononuclear cells in blood at diagnosis portend treatment failure and neurodegeneration in pediatric LCH. Blood. 2025; 146:206-218.

Lopez-Nunez, OF; Ranganathan, S. Unveiling distinctive patterns in pediatric PSC-IBD: Time for a tailored histopathologic index?. Journal of Pediatric Gastroenterology and Nutrition. 2025; 80:257-259.

Malik, F; Koo, SC; Din, NU; Tran, QT; Lopez-Nunez, O; Barresi, S; Vallese, S; Milano, G; Miele, E; Clay, MR; Alaggio, R; Orr, BA. Reappraisal of soft tissue myoepithelial tumors by DNA methylation profiling reveals an epigenetically distinct group of mostly fusion-driven neoplasms. Virchows Archiv: an international journal of pathology. 2025; 486:573-584.

Mehta, P; Pan, Z; Furuta, GT; Kliewer, K; Gonsalves, N; Dellon, ES; Katzka, DA; Aceves, SS; Arva, NC; Chehade, M; Menard-Katcher, P; Peterson, KA; Yang, GY; Rothenberg, ME. Empiric elimination diets for eosinophilic esophagitis: Barriers, facilitators, and impact on quality of life. The Journal of Allergy and Clinical Immunology: in Practice. 2025; 13:434-436.

Mehta, PA; Nelson, A; Loveless, S; Lane, A; Fukuda, T; Teusink-Cross, A; Elder, D; Lagory, D; Miller, E; Cancelas, JA; Edwards, S; Chihanga, T; Wells, SI; Davies, SM. Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia. Blood Advances. 2025; 9:1927-1939.

Messina, M; Barnes, S; Setchell, KD. Perspective: Isoflavones-Intriguing Molecules but Much Remains to Be Learned about These Soybean Constituents. Advances in nutrition (Bethesda, Md.). 2025; 16:100418.

Mohammad, M; Kristensen, AW; Hartmann, JP; Wareham, NE; Buttar, SN; Greve, AM; Lund, TK; Jensen, K; Schultz, HH L; Perch, M; Berg, RM G; Mortensen, J. Survival in Patients With Evidence of Pulmonary Thromboembolism on Ventilation-Perfusion SPECT 12 Weeks After Double Lung Transplantation: A Retrospective Cohort Study. Clinical Transplantation. 2025; 39:e70103.

Morrison, A; Wassmer, T; Swauger, S; Berklite, L; Pennesi, C. Virilization, Ovarian Hyperthecosis, and Torsion Masquerading as Malignancy: A Case Report. Journal of Pediatric and Adolescent Gynecology. 2025; 38:425-428.

Murray, A; Marquez, SP R; Krishnamurthy, M; Lopez-Nunez, O; Gurria, JP; Trout, AT; Almazan, S; Mutyala, K; Grisotti, G; Shah, A; Howell, J. Multifocal Insulinoma as the Unique Presenting Feature of Multiple Endocrine Neoplasia Type 1 in an Adolescent. Hormone Research in Paediatrics: from developmental endocrinology to clinical research. 2025; 98:75-83.

Myers, KC; Davies, SM; Lutzko, C; Wahle, R; Grier, DD; Aubert, G; Norris, K; Baird, DM; Koga, M; Ko, AC; Amano, T; Amano, M; Yu, H; Ko, MS H. Clinical Use of ZSCAN4 for Telomere Elongation in Hematopoietic Stem Cells. 2025; 4:EVIDoa2400252.

Patel, A; Göbel, K; Ille, S; Hinz, F; Schoebe, N; Bogumil, H; Meyer, J; Brehm, M; Kardo, H; Schrimpf, D; Loose, M; Schlesner, M; Sill, M; Sahm, F. Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors. Nature Medicine. 2025; 31:1567-1577.

Pavlisko, EN; Neely, ML; Wikenheiser-Brokamp, KA; Fishbein, GA; Litzky, L; Farver, CF; Pal, P; He, M; Illei, PB; Deshpande, C; Lang, JE; Belperio, JA; Palmer, SM; Sweet, SC. Diagnostic alignment to optimize inter-rater reliability among lung transplant pathologists. The Journal of Heart and Lung Transplantation. 2025; 44:173-181.

Pressey, JG; Toebbe, B; Chandler, M; Szabo, S; Pitt, S. 23P Pre-diagnostic imaging reveals rapid emergence and progression of small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Implications for monitoring carriers of SMARCA4 germline pathogenic variants (GPVs). ESMO Open. 2025; 10:104332.

Rai, S; Keegan, D; Wikenheiser-Brokamp, KA; Pajor, NM. Palliative Mechanical Ventilation for Niemann Pick Disease Type C2 Related Interstitial Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a2347.

Roy, S; Fussell, AM; Jordan, D; Kadri, S; Leon, A; Schmidt, RJ; Temple-Smolkin, RL; Merker, JD. Development of a Body of Knowledge for the Clinical Bioinformatician: Perspectives from the Association for Molecular Pathology's Clinical Bioinformatician Body of Knowledge Steering Committee. The Journal of molecular diagnostics : JMD. 2025; 27:541-545.

Rubrecht, AE; Shenoy, A. Rhabdomyosarcoma Classification: Refining Our Understanding. Surgical Pathology Clinics. 2025; 18:301-311.

Ruffolo, B; Vicente-Muñoz, S; Mehta, KY; Rivera-Cruz, CM; Zhao, X; Romick, L; Setchell, KD R; Lane, A; Wells, SI. The Fanconi Anemia Pathway Inhibits mTOR Signaling and Prevents Accelerated Translation in Head and Neck Cancer Cells. Cancers. 2025; 17:2583.

Schenker, RB; Ramirez, CB; Jang, C; Allayee, H; Zhao, X; Setchell, KD R; Kohli, R; Goran, MI. Dihydroxyacetone phosphate is a novel predictor of hepatic fibrosis in Latino adolescents with obesity. Journal of Pediatric Gastroenterology and Nutrition. 2025; 80:174-181.

Schoedel, K; Hegazy, S; Zilla, ML; Chang, J; Nacev, BA. Novel dual gene fusions identified in a late pulmonary metastasis of an infantile fibrosarcoma-like tumor. Virchows Archiv: an international journal of pathology. 2025; 486:1069-1072.

Schukow, CP; Herndon, C; Lopez-Nunez, OF; Chen, SD; Kahwash, S. Exploring the Impact and Prospects of Social Media in Advancing Pediatric Pathology. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2025; 28:3-14.

Schwartz, TS; Mouzaki, M; Berklite, L; Lopez-Nunez, OF; Miethke, A; Xanthakos, SA; Vitale, DS. Pediatric endoscopic ultrasound-guided liver biopsy: 3-year experience. Journal of Pediatric Gastroenterology and Nutrition. 2025; 80:920-925.

Setayesh, T; Chi, M; Oestreicher, Z; Sakabe, M; Seu, K; Zhu, Z; Kaur, H; Tijani, A; Xin, M; Shova, A; Balla, J; VandenHeuvel, K; Hu, YC; Malik, P. A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea. Blood. 2025; 146:13-28.

Shabanian, M; Taylor, Z; Woods, C; Bernieh, A; Dillman, J; He, L; Ranganathan, S; Picarsic, J; Somasundaram, E. Liver fibrosis classification on trichrome histology slides using weakly supervised learning in children and young adults. Journal of Pathology Informatics. 2025; 16:100416.

Shankar, N; Kreiger, PA; Oldridge, DA; Picarsic, J; Arnold, MA. Digital Pathology and Artificial Intelligence in Pediatric Pathology. Surgical Pathology Clinics. 2025; 18:397-406.

Shi, Z; Zhang, X; Yang, H; Zheng, X; Niu, M; Zhang, Y; Yuan, P; Wei, W; Huang, G; Fang, R; Chen, L. Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells. Blood Science. 2025; 7:e00236.

Srinivasan, S; Mishra, S; Fan, KK H; Wang, L; Im, J; Segura, C; Mukherjee, N; Huang, G; Rao, M; Ma, C; Zhang, N. Age-Dependent Bi-Phasic Dynamics of Ly49+CD8+ Regulatory T Cell Population. Aging Cell. 2025; 24:e14461.

Stanek, J. Placental fetal vascular malperfusion in maternal diabetes mellitus. Journal of Perinatal Medicine: official journal of the World Association of Perinatal Medicine. 2025; 53:179-187.

Tang, X; Zilla, ML; Jiang, W; He, Y; Starr, D; Li, L; Tong, L; Wang, C; Wang, W; Yang, K; Yin, R; Zhao, C. The significance of extensive HPV genotyping for cervical high-grade neoplasia among women with atypical glandular cells. American Journal of Clinical Pathology. 2025; 163:134-142.

Thomsen, RS; Mohammad, M; Ragborg, LC; Dragsted, C; Ohrt-Nissen, S; Gehrchen, M; Dahl, B; Berg, RM G; Mortensen, J. Dual test gas pulmonary diffusing capacity in patients with idiopathic scoliosis 40 years after diagnosis. Experimental Physiology. 2025; 110:610-622.

Tolson, HC; Alzahrani, F; Singh, R; Lorsbach, R; Grebe, TA; Prakash, S; Picarsic, J; Dupuy, E; Price, H. Granulomatous Variant of Giant Centrifugal Miliaria Profunda in an 8-Month-Old Boy: Expanding the Dermatologic Phenotype of Cardiofaciocutaneous Syndrome. Pediatric Dermatology. 2025; 42:599-602.

Upadhyay, P; Jones, TE; Mirza, KM; Lopez-Nunez, OF; Herman, M; Mirzabeigi, Y; Price, T; Alam, F; Baskota, SU. Pathology observerships and externships for international medical graduates: Insights from a MatchToPath.com survey. Academic Pathology. 2025; 12:100178.

Wendroth, R; Paisley, A; Marsh, R; Schulert, G; Wikenheiser-Brokamp, KA; Burg, G. Lung Disease in Systemic Juvenile Idiopathic Arthritis: An Atypical Path to Diagnosis. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7865.

Wooton-Kee, CR; Yalamanchili, HK; Mohamed, I; Hassan, M; Setchell, KD R; Narvaez Rivas, M; Coskun, AK; Putluri, V; Putluri, N; Jalal, P; Schilsky, ML; Moore, DD. Changes in the FXR-cistrome and alterations in bile acid physiology in Wilson disease. Hepatology Communications. 2025; 9:e0707.

Zamulko, O; Hanna, GJ; Adkins, D; Pan, J; Romano, A; Lehn, M; Forsythe, A; Allen, CL; Wikenheiser-Brokamp, KA; Lemmon, C; El-Gamal, D; Rai, S; Wise-Draper, TM. Amivantamab for recurrent/metastatic adenoid cystic carcinoma: A multicenter, single-arm, phase 2 clinical trial. Journal of Clinical Oncology. 2025; 43:6101.

Zhao, J; Zhao, X; Mizuno, T; Irie, K; Devarajan, P; Brunner, HI; Setchell, KD R. Volumetric Absorptive Microsampling Combined with Mass Spectrometry to Support Pharmacokinetically-Guided Precision Dosing of Mycophenolate Mofetil in Pediatric Lupus Nephritis Patients. The journal of applied laboratory medicine. 2025; 10:806-819.

Zhong, F; Zilla, ML; Sun, Y; Zeng, X; Zhang, H; Xiao, J; Tao, X; Zhao, C. The Significance of Extended HPV Genotyping for Detecting Endocervical Glandular Neoplasia for Atypical Glandular Cells. Journal of Lower Genital Tract Disease. 2025; 29:223-228.

Zhu, B; Pitts, MG; Buoncristiani, MD; Bryant, LT; Lopez-Nunez, O; Gurria, JP; Shedlock, C; Ribas, R; Keohane, S; Liu, J; Allison, DB; Evers, BM; Sun, RC; Rellinger, EJ. GDP-mannose 4,6-dehydratase is a key driver of MYCN-amplified neuroblastoma core fucosylation and tumorigenesis. Oncogene: Including Oncogene Reviews. 2025; 44:1272-1283.