Pathology

Pathology

Publications

Bartlett, AL; Romick-Rosendale, L; Nelson, A; Abdullah, S; Luebbering, N; Bartlett, J; Brusadelli, M; Palumbo, JS; Lake, K; Litts, B; et al. Tryptophan metabolism is dysregulated in individuals with Fanconi anemia. Blood Advances. 2021; 5:250-261.

Bedard, MC; Brusadelli, MG; Carlile, A; Ruiz-Torres, S; Lodin, H; Lee, D; Kofron, M; Lambert, PF; Lane, A; Ameziane, N; et al. Patient-Derived Organotypic Epithelial Rafts Model Phenotypes in Juvenile-Onset Recurrent Respiratory Papillomatosis. Viruses. 2021; 13.

Bedard, MC; de Alarcon, A; Kou, YF; Lee, D; Sestito, A; Duggins, AL; Brusadelli, M; Lane, A; Wikenheiser-Brokamp, KA; Wells, SI; et al. HPV Strain Predicts Severity of Juvenile-Onset Recurrent Respiratory Papillomatosis with Implications for Disease Screening. Cancers. 2021; 13.

Benzaquen, S; Kaini, N; Gupta, E; Litwin, D; Wikenheiser-Brokamp, KA; Aragaki-Nakahodo, A. Women Presenting With Asthma and Persistent Wheezing: A Case Series. Chest. 2021; 159:e267-e275.

Bigenwald, C; Le Berichel, J; Wilk, CM; Chakraborty, R; Chen, ST; Tabachnikova, A; Mancusi, R; Abhyankar, H; Casanova-Acebes, M; Laface, I; et al. BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology. Nature Medicine. 2021; 27:851-861.

Bogue, AL; Panmanee, W; McDaniel, CT; Mortensen, JE; Kamau, E; Actis, LA; Johannigman, JA; Schurr, MJ; Satish, L; Kotagiri, N; et al. AB569, a non-toxic combination of acidified nitrite and EDTA, is effective at killing the notorious Iraq/Afghanistan combat wound pathogens, multi-drug resistant Acinetobacter baumannii and Acinetobacter spp. PLoS ONE. 2021; 16.

Chandra, S; Mizuno, K; Zhao, J; Davies, SM; Marsh, RA; Fukuda, T; Setchell, KD R; Vinks, AA; Mehta, PA. Test-dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non-malignant disorders. British Journal of Clinical Pharmacology. 2021.

Chen, L; Wang, G; Long, X; Hou, H; Wei, J; Cao, Y; Tan, J; Liu, W; Meng, F; Huang, L; et al. Dynamics of Blood Viral Load Is Strongly Associated with Clinical Outcomes in Coronavirus Disease 2019 (COVID-19) Patients: A Prospective Cohort Study. Journal of Molecular Diagnostics. 2021; 23:10-18.

Chinnarasu, S; Alogaili, F; Bove, KE; Jaeschke, A; Hui, DY. Hepatic LDL receptor-related protein-1 deficiency alters mitochondrial dynamics through phosphatidylinositol 4,5-bisphosphate reduction. Journal of Biological Chemistry. 2021; 296.

Czyzewski, T; Daniel, N; Rochman, M; Caldwell, J; Osswald, G; Collins, M; Rothenberg, M; Savir, Y. Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features. IEEE Open Journal of Engineering in Medicine and Biology. 2021; PP:1-1.

Dellon, ES; Collins, MH; Katzka, DA; Hudgens, S; Lan, L; Williams, J; Vera-Llonch, M; Hirano, I. Improvements in Dysphagia and Pain With Swallowing in Patients With Eosinophilic Esophagitis Receiving Budesonide Oral Suspension. Clinical Gastroenterology and Hepatology. 2021; 19:699-706.e4.

Dellon, ES; Collins, MH; Katzka, DA; Mukkada, VA; Falk, GW; Morey, R; Goodwin, B; Eisner, JD; Lan, L; Desai, NK; et al. Long-Term Treatment of Eosinophilic Esophagitis with Budesonide Oral Suspension. Clinical Gastroenterology and Hepatology. 2021.

Dellon, ES; Collins, MH; Rothenberg, ME; Assouline-Dayan, Y; Evans, L; Gupta, S; Schoepfer, A; Straumann, A; Safroneeva, E; Rodriguez, C; et al. Long-term Efficacy and Tolerability of RPC4046 in an Open-Label Extension Trial of Patients With Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2021; 19:473-483.e17.

Deutsch, GH; Wikenheiser-Brokamp, KA. Congenital and Developmental Causes of Cystic Lung Disease. Diffuse Cystic Lung Diseases. 2021.

Fan, C; Zhao, C; Zhang, F; Kesarwani, M; Tu, Z; Cai, X; Davis, AK; Xu, L; Hochstetler, CL; Chen, X; et al. Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition. Proceedings of the National Academy of Sciences of the United States of America. 2021; 118.

Fan, T; Feng, X; Yokota, A; Liu, W; Tang, Y; Yan, X; Xiao, H; Wang, Y; Deng, Z; Zhao, P; et al. Arsenic Dispensing Powder Promotes Erythropoiesis in Myelodysplastic Syndromes via Downregulation of HIF1A and Upregulation of GATA Factors. American Journal of Chinese Medicine. 2021; 49:461-485.

Ferrell, J; Sharp, S; Kumar, A; Jordan, M; Picarsic, J; Nelson, A. Discrepancies between F-18-FDG PET/CT findings and conventional imaging in Langerhans cell histiocytosis. Pediatric Blood and Cancer. 2021; 68.

Garg, PM; Bernieh, A; Hitt, MM; Kurundkar, A; Adams, KV; Blackshear, C; Maheshwari, A; Saad, AG. Incomplete resection of necrotic bowel may increase mortality in infants with necrotizing enterocolitis. Pediatric Research. 2021; 89:163-170.

Hall, ES; McAllister, JM; Kelly, EA; Setchell, KD R; Megaraj, V; Jimenez, KL; Nidey, N; Greenberg, JM; Wexelblatt, SL. Regional comparison of self-reported late pregnancy cigarette smoking to mass spectrometry analysis. Journal of Perinatology. 2021.

Hawkins, PE; Murphy, DJ; McCormack, FX; Wikenheiser-Brokamp, KA; McCarthy, C. Neoplasms That Present as Multicystic Lung Disease. Diffuse Cystic Lung Diseases. 2021.

Hayashi, H; Osaka, S; Sakabe, K; Fukami, A; Kishimoto, E; Aihara, E; Sabu, Y; Mizutani, A; Kusuhara, H; Naritaka, N; et al. Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Stem Cell Reports. 2021; 16:309-323.

Hayes, D; Darland, LK; Hjelm, MA; Mansour, HM; Wikenheiser-Brokamp, KA. To treat or not to treat: CFTR modulators after lung transplantation. Pediatric Transplantation. 2021; 25.

Hertel, PM; Bull, LN; Thompson, RJ; Goodrich, NP; Ye, W; Magee, JC; Squires, RH; Bass, LM; Heubi, JE; Kim, GE; et al. Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children with Monogenic Cholestasis. Journal of Pediatric Gastroenterology and Nutrition. 2021.

Hirano, I; Collins, MH; Katzka, DA; Mukkada, VA; Falk, GW; Morey, R; Desai, NK; Lan, L; Williams, J; Dellon, ES; et al. Budesonide Oral Suspension Improves Outcomes in Patients With Eosinophilic Esophagitis: Results from a Phase 3 Trial. Clinical Gastroenterology and Hepatology. 2021.

Hirano, I; Collins, MH; Katzka, DA; Mukkada, VA; Falk, GW; Morey, R; Mukasa, L; Desai, NK; Williams, J; Dellon, ES. Reply. Clinical Gastroenterology and Hepatology. 2021.

Hughley, E; Nehus, EJ; VandenHeuvel, K; Augsburger, BD; Jain, NG; Lucky, AW. Glomerulonephritis in Youth With Dystrophic Epidermolysis Bullosa. Kidney International Reports. 2021; 6:538-543.

Jackson, BR; Ye, Y; Crawford, JM; Becich, MJ; Roy, S; Botkin, JR; de Baca, ME; Pantanowitz, L. The Ethics of Artificial Intelligence in Pathology and Laboratory Medicine: Principles and Practice. 2021; 8.

Jain, P; Surrey, LF; Straka, J; Russo, P; Womer, R; Li, MM; Storm, PB; Waanders, AJ; Hogarty, MD; Resnick, AC; et al. BRAF fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers. Pediatric Blood and Cancer. 2021; 68.

Jones, TE; Zou, J; Tseng, GC; Roy, S; Bhargava, R. The Utility of Next-Generation Sequencing in Advanced Breast and Gynecologic Cancers. American Journal of Clinical Pathology. 2021.

Jose, S; Mukherjee, A; Horrigan, O; Setchell, KD R; Zhang, W; Moreno-Fernandez, ME; Andersen, H; Sharma, D; Haslam, DB; Divanovic, S; et al. Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice. Mucosal Immunology. 2021; 14:500-510.

Karkoska, K; Ricci, K; VandenHeuvel, K; Trout, AT; Smith, EA; Kotagal, M; Weiss, B. Metastatic neuroblastoma masquerading as infantile hemangioma in a 4-month-old child. Pediatric Blood and Cancer. 2021; 68.

Kohli, R; Bove, KE; Xanthakos, SA. Non-Alcoholic Fatty Liver Disease in Children. Liver Disease in Children. 2021.

Lin, Y; Watanabe-Chailland, M; Zheng, Y. Protocol for structural and biochemical analyses of RhoA GTPase. STAR Protocols. 2021; 2.

Liu, X; Zhao, Y; Luedke, C; Jug, R; Yang, LH; Lu, M; Pan, Z; Wang, D; Lorsbach, R; Shi, Y; et al. Infantile leukemia-What factors determine its distinct biological nature? Clinicopathological study of 78 cases. International Journal of Laboratory Hematology. 2021.

Lopez-Nunez, O; Alaggio, R; John, I; Ciolfi, A; Pedace, L; Mastronuzzi, A; Gianno, F; Giangaspero, F; Rossi, S; Donofrio, V; et al. Melanotic Neuroectodermal Tumor of Infancy (MNTI) and Pineal Anlage Tumor (PAT) Harbor A Medulloblastoma Signature by DNA Methylation Profiling. Cancers. 2021; 13.

Lopez-Nunez, O; Cafferata, B; Santi, M; Ranganathan, S; Pearce, TM; Kulich, SM; Bailey, KM; Broniscer, A; Rossi, S; Zin, A; et al. The spectrum of rare central nervous system (CNS) tumors with EWSR1-non-ETS fusions: experience from three pediatric institutions with review of the literature. Brain Pathology. 2021; 31:70-83.

Lopez-Nunez, O; Srivastava, P; Wheeler, BJ; Oakes, N; Thomas, H; Nowalk, A; Wheeler, S. Pediatric decision limits for serologic screening of Lyme disease. Clinical Biochemistry. 2021; 91:59-62.

Lopez-Nunez, O; Surrey, LF; Alaggio, R; Herradura, A; McGough, RL; John, I. Novel APOD-GLI1 rearrangement in a sarcoma of unknown lineage. Histopathology. 2021; 78:338-340.

Lötstedt, B; Boyer, D; Visner, G; Freiberger, D; Lurie, M; Kane, M; DiFilippo, C; Lundeberg, J; Narvaez-Rivas, M; Setchell, K; et al. The impact of gastrointestinal dysmotility on the aerodigestive microbiome of pediatric lung transplant recipients. Journal of Heart Transplantation. 2021; 40:210-219.

Luo, H; Liu, D; Liu, W; Wang, G; Chen, L; Cao, Y; Wei, J; Xiao, M; Liu, X; Huang, G; et al. Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms. European Journal of Human Genetics. 2021.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

Ma, C; Schoepfer, AM; Safroneeva, E; COREOS Collaborators, . Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021.

Milewski, D; Shukla, S; Gryder, BE; Pradhan, A; Donovan, J; Sudha, P; Vallabh, S; Pyros, A; Xu, Y; Barski, A; et al. FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma. Oncogene. 2021; 40:2182-2199.

Moreno-Fernandez, ME; Giles, DA; Oates, JR; Chan, CC; Damen, MS M A; Doll, JR; Stankiewicz, TE; Chen, X; Chetal, K; Karns, R; et al. PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. Cell Metabolism. 2021; 33:1187-1204.e9.

Muthiah, N; Nowicki, KW; Picarsic, JL; D’Angelo, MP; Marker, DF; Andrews, EG; Monaco, EA; Niranjan, A. Three decades of progress from surgery to medical therapy for isolated neuroaxis BRAF V600E–positive Langerhans cell histiocytosis management: illustrative case. 2021; 1.

Narciso, MG; Hoeting, B; James, JM; VandenHeuvel, K; Nasimuzzaman, M. A mutant fibrinogen that is unable to form fibrin can improve renal phenotype in mice with sickle cell anemia. 2021.

Niss, O; Lorsbach, RB; Berger, M; Chonat, S; McLemore, M; Buchbinder, D; McCavit, T; Shaffer, LG; Simpson, J; Schwartz, JH; et al. Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR). Blood Cells, Molecules, and Diseases. 2021; 87.

Papke, DJ; Fisch, AS; Ranganathan, S; O’Neill, A; Breen, M; Church, AJ; Perez-Atayde, AR; Al-Ibraheemi, A. Undifferentiated Embryonal Sarcoma of the Liver With Rhabdoid Morphology Mimicking Carcinoma: Expanding the Morphologic Spectrum or a Distinct Variant?. Pediatric and Developmental Pathology. 2021.

Pradhan-Sundd, T; Liu, S; Singh, S; Poddar, M; Ko, S; Bell, A; Franks, J; Huck, I; Stolz, D; Apte, U; et al. Dual β-Catenin and γ-Catenin Loss in Hepatocytes Impacts Their Polarity through Altered Transforming Growth Factor-β and Hepatocyte Nuclear Factor 4α Signaling. American Journal of Pathology. 2021; 191:885-901.

Qu, S; Jia, Y; Wang, H; Ai, X; Xu, Z; Qin, T; Pan, L; Li, B; Huang, G; Gale, RP; et al. STAT3 and STAT5B mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms. Leukemia and Lymphoma. 2021; 62:1506-1509.

Qu, S; Li, B; Qin, T; Xu, Z; Pan, L; Hu, N; Huang, G; Gale, RP; Xiao, Z. Molecular and clinical features of myeloid neoplasms with somatic DDX41 mutations. British Journal of Haematology. 2021; 192:1006-1010.

Ranganathan, S. Commentary: Late Allograft Fibrosis and Inflammation - An Unexpected Finding with Need for More Aggressive Treatment?. Transplantation. 2021.

Romero-Lopez, MD M; Oria, M; Watanabe-Chailland, M; Varela, MF; Romick-Rosendale, L; Peiro, JL. Lung Metabolomics Profiling of Congenital Diaphragmatic Hernia in Fetal Rats. Metabolites. 2021; 11.

Safroneeva, E; Pan, Z; King, E; Martin, LJ; Collins, MH; Yang, G; Capocelli, KE; Arva, NC; Abonia, JP; Atkins, D; et al. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms Following Dilation in Adults with Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2021.

Sauter, SL; Zhang, X; Romick-Rosendale, L; Wells, SI; Myers, KC; Brusadelli, MG; Poff, CB; Brown, DR; Panicker, G; Unger, ER; et al. Human Papillomavirus Oral- and Sero- Positivity in Fanconi Anemia. Cancers. 2021; 13.

Setchell, KD R; Heubi, JE. Disorders of Bile Acid Synthesis and Metabolism in Children. Liver Disease in Children. 2021.

Sharma, BK; Mureb, D; Murab, S; Rosenfeldt, L; Francisco, B; Cantrell, R; Karns, R; Romick-Rosendale, L; Watanabe-Chailland, M; Mast, J; et al. Fibrinogen activates focal adhesion kinase (FAK) promoting colorectal adenocarcinoma growth. Journal of Thrombosis and Haemostasis. 2021.

Stanek, J. Temporal heterogeneity of placental segmental fetal vascular malperfusion: timing but not etiopathogenesis. Virchows Archiv. 2021; 478:905-914.

Stanek, J. CD34 immunostain increases sensitivity of the diagnosis of fetal vascular malperfusion in placentas from ex-utero intrapartum treatment. Journal of Perinatal Medicine. 2021; 49:203-208.

Stanek, J. Grading placental fetal vascular malperfusion and short-term perinatal outcome. Polish Journal of Pathology. 2021; 71:291-300.

Tang Girdwood, SC; Tang, PH; Murphy, ME; Chamberlain, AR; Benken, LA; Jones, RL; Stoneman, EM; Kaplan, JM; Vinks, AA. Demonstrating Feasibility of an Opportunistic Sampling Approach for Pharmacokinetic Studies of β-Lactam Antibiotics in Critically Ill Children. Journal of Clinical Pharmacology. 2021; 61:565-573.

Tang, Y; Xu, Q; Hu, L; Yan, X; Feng, X; Yokota, A; Wang, W; Zhan, D; Krishnamurthy, D; Ochayon, DE; et al. Tumor Microenvironment-Derived R-spondins Enhance Anti-Tumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy. Cancer Discovery. 2021.

Wang, H; Lu, J; Chen, X; Schwalbe, M; Gorka, JE; Mandel, JA; Wang, J; Goetzman, ES; Ranganathan, S; Dobrowolski, SF; et al. Acquired deficiency of peroxisomal dicarboxylic acid catabolism is a metabolic vulnerability in hepatoblastoma. Journal of Biological Chemistry. 2021; 296.

Wang, H; Lu, J; Mandel, JA; Zhang, W; Schwalbe, M; Gorka, J; Liu, Y; Marburger, B; Wang, J; Ranganathan, S; et al. Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas. CMGH Cellular and Molecular Gastroenterology and Hepatology. 2021; 12:199-228.

Wang, MJ; Liu, WY; Wang, XY; Li, YM; Xiao, HY; Quan, RC; Huang, G; Hu, XM. Autophagy Gene Panel-Based Prognostic Model in Myelodysplastic Syndrome. Frontiers in Oncology. 2021; 10.

Wang, Y; Pandey, RN; Roychoudhury, K; Milewski, D; Kalin, TV; Szabo, S; Pressey, JG; Hegde, RS. Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis. Molecular Cancer Therapeutics. 2021; 20:803-815.

Wangsiricharoen, S; Zhong, M; Ranganathan, S; Matoso, A; Argani, P. ALK-rearranged Renal Cell Carcinoma (RCC): A Report of 2 Cases and Review of the Literature Emphasizing the Distinction Between VCL-ALK and Non-VCL-ALK RCC. International Journal of Surgical Pathology. 2021.

Wortmann, SB; Zietkiewicz, S; Guerrero-Castillo, S; Feichtinger, RG; Wagner, M; Russell, J; Ellaway, C; Mróz, D; Wyszkowski, H; Weis, D; et al. Neutropenia and intellectual disability are hallmarks of biallelic and de novo CLPB deficiency. Genetics in Medicine. 2021.

Xing, J; Han, M; Monaco, SE; Dhir, R; Roy, S; Pantanowitz, L. An institutional experience evaluating hTERT immunostaining in 100 consecutive ThinPrep urine specimens. Journal of the American Society of Cytopathology. 2021; 10:88-93.

Xu, Q; Tang, Y; Huang, G. Innate immune responses in RNA viral infection. Frontiers of Medicine. 2021; 15:333-346.

Yi, W; Liu, B; Zhou, Y; Liao, D; Qiao, X; Gao, D; Xie, T; Yao, Q; Zhang, Y; Qiu, Y; et al. Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration. Cell Reports. 2021; 34.

Zhao, J; Sharat, C; Mehta, PA; Mizuno, K; Vinks, AA; Setchell, KD R. Paperspray Ionization Mass Spectrometry as a Tool for Predicting Real-Time Optimized Dosing of the Chemotherapeutic Drug Melphalan. Journal of Applied Laboratory Medicine. 2021; 6:625-636.

Zhao, J; Sui, P; Wu, B; Chen, A; Lu, Y; Hou, F; Cheng, X; Cui, S; Song, J; Huang, G; et al. Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model. Leukemia. 2021; 35:595-600.