Higano Lab

Publications

Munidasa, S; Higano, NS; Willmering, M; Matheson, AM; Fleck, RJ; Kingma, PS; Hysinger, EB; Woods, JC. Structural and Functional Lung Assessment in Neonates With Moderate to Severe Bronchopulmonary Dysplasia Using 3D Ultra-Short Echo Time MRI. Journal of Magnetic Resonance Imaging. 2025.

Boles, CR; Gunatilaka, CC; Xiao, Q; Woods, JC; Kingma, PS; Higano, NS; Nauman, EA; Bates, AJ. Tracheal Work of Breathing in Neonates With Tracheoesophageal Fistula Before and After Surgical Repair via Computational Fluid Dynamics Assessment. Journal of Pediatric Surgery. 2025; 60(12):162630.

Munidasa, S; Higano, NS; Willmering, MM; Bdaiwi, AS; Cordon, XH; Elias, DB; Fleck, RJ; Kingma, PS; Hysinger, EB; Woods, JC. Serial MRI Measures Short-term Parenchymal Changes in Neonatal Bronchopulmonary Dysplasia. Chest. 2025.

Stewart, NJ; Higano, NS; Wucherpfennig, L; Triphan, SMF; Simmons, A; Smith, LJ; Wielpütz, MO; Woods, JC; Wild, JM. Pulmonary MRI in Newborns and Children. Journal of Magnetic Resonance Imaging. 2025; 61(5):2094-2115.

Munidasa, S; Higano, NS; Zinjal, R; Willmering, M; Kingma, PS; Critser, PJ; Hysinger, E; Woods, JC. Structural and Functional Cardiopulmonary Magnetic Resonance Imaging in Neonates With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211(Supplement_1):a1279-a1279.

Mohanakrishnan, M; Munidasa, SR; Higano, NS; Willmering, M; Hoyos Cordon, X; Bullard Elias, D; Bates, AJ; Kingma, PS; Hysinger, EB; Woods, JC. Serial MRI Evaluation of Tracheomalacia Changes in Neonates With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211(Supplement_1):a1284-a1284.

Munidasa, SR; Higano, NS; Willmering, M; Bdaiwi, AS; Hoyos Cordon, X; Bullard Elias, D; Kingma, PS; Hysinger, EB; Woods, JC. Magnetic Resonance Imaging Captures the Short-Term Trajectory of Parenchymal Lung Disease in Infants With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211(Supplement_1):a1280-a1280.

Jo, S; Arroyo, R; Marks, K; Higano, NS; Bates, A; Von Allenmen, D; Woods, JC; Kingma, PS. Evaluation of Magnetic Resonance Imaging (MRI) Anatomic Risk Factors to Predict Outcomes in Patients With Esophageal Atresia (EA) American Journal of Respiratory and Critical Care Medicine. 2025; 211(Supplement_1):a2299-a2299.

Boles, C; Gunatilaka, CC; Xiao, Q; Woods, JC; Kingma, PS; Higano, NS; Bates, A. Computational Fluid Dynamics Analysis of Tracheal Pressure Difference in Neonates With Tracheoesophageal Fistulas Before and After Surgical Repair. American Journal of Respiratory and Critical Care Medicine. 2025; 211(Abstracts):a5119-a5119.

Mukthapuram, S; Donaher, A; Higano, NS; Rowe, JA; Tkach, JA; Woods, JC; Kingma, PS. Magnetic Resonance Imaging Assessment of Pulmonary Vascularity in Preterm Infants with Bronchopulmonary Dysplasia. Neonatology. 2025; 122(1):76-83.

Zak, SM; Onge, IS; Higano, NS; Bates, AJ; Gandhi, D; Fleck, RJ; Kingma, PS; Woods, JC; Hysinger, EB. Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia. Pediatric Pulmonology. 2025; 60(1):e27383.

Dianova, E; Higano, NS; Mcnelis, KM; Ehrlich, SR; Liu, C; Woods, JC; Kingma, PS. Association of Early Nutrition with Bronchopulmonary Dysplasia Severity and Magnetic Resonance Imaging Lung Characteristics in Preterm Infants. Neonatology. 2025; 122(3):319-328.

Gunatilaka, CC; Mckenzie, C; Xiao, Q; Higano, NS; Woods, JC; Bates, AJ. Effect of airway wall motion on particle deposition and delivery in the neonatal trachea. Journal of Aerosol Science. 2024; 182:106450.

Von Allmen, DC; Hysinger, EB; Bates, AJ; Higano, NS; Garrison, A; Walther, A; De Alarcon, A; Woods, J; Kingma, P. Correlation of Tracheomalacia Severity With Esophageal Gap Length as Assessed by Ultrashort Echo-time MRI. Journal of Pediatric Surgery. 2024; 59(11):161880.

Bjorkman, KR; Miles, KG; Bellew, LE; Schneider, KA; Magness, SM; Higano, NS; Ollberding, NJ; Hoyos Cordon, X; Hirsch, RM; Hysinger, E; Woods, JC; Critser, PJ. Patent Ductus Arteriosus and Lung Magnetic Resonance Imaging Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. 2024; 210(3):318-328.

Higano, NS. Editorial for "Assessment of Pulmonary Ventilation Using 3D Ventilation Flow-Weighted and Ventilation-Weighted Maps From 3D Ultrashort Echo-Time (UTE) MRI". Journal of Magnetic Resonance Imaging. 2024; 60(2):495-496.

Gandhi, DB; Higano, NS; Hahn, AD; Gunatilaka, CC; Torres, LA; Fain, SB; Woods, JC; Bates, AJ. Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI. Biomedical Physics and Engineering Express. 2024; 10(3).

Gunatilaka, CC; Mckenzie, C; Hysinger, EB; Xiao, Q; Higano, NS; Woods, JC; Bates, AJ. Tracheomalacia Reduces Aerosolized Drug Delivery to the Lung. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2024; 37(1):19-29.

Giltmier, AJ; Higano, NS; Woods, JC; Kingma, PS. Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging. Pediatric Pulmonology. 2024; 59(1):55-62.

Stewart, NJ; Higano, NS; Mukthapuram, S; Willmering, MM; Loew, W; West, M; Arnsperger, A; Pratt, R; Rao, MR; Schulte, RF; Wild, JM; Woods, JC. Initial feasibility and challenges of hyperpolarized 129 Xe MRI in neonates with bronchopulmonary dysplasia. Magnetic Resonance in Medicine. 2023; 90(6):2420-2431.

Marks, KT; Higano, NS; Kotagal, M; Woods, JC; Kingma, PS. Magnetic Resonance Imaging-Based Evaluation of Anatomy and Outcome Prediction in Infants with Esophageal Atresia. Neonatology. 2023; 120(2):185-195.

Tkach, JA; Higano, NS; Taylor, MD; Moore, RA; Hossain, M; Huang, G; Spielberg, DR; Fain, SB; Kingma, PS; Woods, JC. Quantitative cardiopulmonary magnetic resonance imaging in neonatal congenital diaphragmatic hernia. Pediatric Radiology. 2022; 52(12):2306-2318.

Gunatilaka, CC; Hysinger, EB; Schuh, A; Xiao, Q; Gandhi, DB; Higano, NS; Ignatiuk, D; Hossain, MM; Fleck, RJ; Woods, JC; Bates, AJ. Predicting tracheal work of breathing in neonates based on radiological and pulmonary measurements. Journal of applied physiology. 2022; 133(4):893-901.

Hysinger, EB; Higano, NS; Critser, PJ; Woods, JC. Imaging in neonatal respiratory disease. Paediatric Respiratory Reviews. 2022; 43:44-52.

Higano, NS; Gandhi, DB; Xiao, Q; Gunatilaka, CC; Hysinger, EB; Fleck, RJ; Woods, JC; Bates, AJ. Virtual Bronchoscopy of Neonatal Airway Malacia via High-Resolution, Respiratory-gated Magnetic Resonance Imaging. American Journal of Respiratory and Critical Care Medicine. 2022; 206(5):e42-e43.

Zou, Q; Torres, LA; Fain, SB; Higano, NS; Bates, AJ; Jacob, M. Dynamic imaging using motion-compensated smoothness regularization on manifolds (MoCo-SToRM). Physics in Medicine and Biology. 2022; 67(14).

Higano, NS; Cao, X; Guo, J; Wang, X; Kroenke, CD; Filuta, AL; Bridges, JP; Woods, JC. Fetal lung development via quantitative biomarkers from diffusion MRI and histological validation in rhesus macaques. Journal of Perinatology. 2022; 42(7):866-872.

Adaikalam, SA; Higano, NS; Hysinger, EB; Bates, AJ; Fleck, RJ; Schapiro, AH; House, MA; Nathan, AT; Ahlfeld, SK; Brady, JM; Woods, JC; Kingma, PS. Tracheostomy prediction model in neonatal bronchopulmonary dysplasia via lung and airway MRI. Pediatric Pulmonology. 2022; 57(4):1042-1050.

Higano, NS; Bates, AJ; Gunatilaka, CC; Hysinger, EB; Critser, PJ; Hirsch, R; Woods, JC; Fleck, RJ. Bronchopulmonary dysplasia from chest radiographs to magnetic resonance imaging and computed tomography: adding value. Pediatric Radiology. 2022; 52(4):643-660.

Adaikalam, SA; Higano, NS; Hysinger, EB; Bates, AJ; Fleck, RJ; Schapiro, AH; House, MA; Nathan, AT; Ahlfeld, SK; Brady, JM; Woods, JC; Kingma, PS. Cover Image, Volume 57, Number 4, April 2022. Pediatric Pulmonology. 2022; 57(4):ii-ii.

Gunatilaka, CC; Hysinger, EB; Schuh, A; Gandhi, DB; Higano, NS; Xiao, Q; Hahn, AD; Fain, SB; Fleck, RJ; Woods, JC; Bates, AJ. Neonates With Tracheomalacia Generate Auto-Positive End-Expiratory Pressure via Glottis Closure. Chest. 2021; 160(6):2168-2177.

Gandhi, DB; Rice, A; Gunatilaka, CC; Higano, NS; Fleck, RJ; De Alarcon, A; Hart, CK; Kuo, I-C; Amin, RS; Woods, JC; Hysinger, EB; Bates, AJ. Quantitative Evaluation of Subglottic Stenosis Using Ultrashort Echo Time MRI in a Rabbit Model. The Laryngoscope. 2021; 131(6):E1971-E1979.

Hahn, AD; Malkus, A; Kammerman, J; Higano, N; Walkup, LL; Woods, J; Fain, SB. Effects of neonatal lung abnormalities on parenchymal R2 * estimates. Journal of Magnetic Resonance Imaging. 2021; 53(6):1853-1861.

Yang, MM; Higano, NS; Gunatilaka, CC; Hysinger, EB; Amin, RS; Woods, JC; Bates, AJ. Subglottic Stenosis Position Affects Work of Breathing. The Laryngoscope. 2021; 131(4):E1220-E1226.

Higano, NS; Ruoss, JL; Woods, JC. Modern pulmonary imaging of bronchopulmonary dysplasia. Journal of Perinatology. 2021; 41(4):707-717.

Bates, AJ; Higano, NS; Woods, JC. Non-Bronchoscopic Assessment of the Airways. In: Diagnostic and Interventional Bronchoscopy in Children. Springer Nature; 2021:155-169.

Trisno, SL; Higano, NS; Kechele, D; Nasr, T; Chung, W; Zorn, AM; Woods, JC; Wells, JM; Kingma, PS. Case Report: Esophageal Bronchus in a Neonate, With Image, Histological, and Molecular Analysis. Frontiers in Pediatrics. 2021; 9:707822.