Walkup Lab

Publications

Plummer, JW; Hussain, R; Bdaiwi, AS; Soderlund, SA; Hoyos, X; Lanier, JM; Garrison, WJ; Parra-Robles, J; Willmering, MM; Niedbalski, PJ; Cleveland, ZI; Walkup, LL. A decay-modeled compressed sensing reconstruction approach for non-Cartesian hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2024; 92:1363-1375.

Plummer, JW; Willmering, MM; Cleveland, ZI; Towe, C; Woods, JC; Walkup, LL. Childhood to adulthood: Accounting for age dependence in healthy-reference distributions in 129 Xe gas-exchange MRI. Magnetic Resonance in Medicine. 2023; 89:1117-1133.

Willmering, MM; Walkup, LL; Niedbalski, PJ; Wang, H; Wang, Z; Hysinger, EB; Myers, KC; Towe, CT; Driehuys, B; Cleveland, ZI; Woods, JC. Pediatric 129 Xe Gas-Transfer MRI-Feasibility and Applicability. Journal of Magnetic Resonance Imaging. 2022; 56:1207-1219.

Walkup, LL; Roach, DJ; Hall, CS; Gupta, N; Thomen, RP; Cleveland, ZI; McCormack, FX; Woods, JC. Cyst Ventilation Heterogeneity and Alveolar Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis. Annals of the American Thoracic Society. 2019; 16:1008-1016.

Walkup, LL; Myers, K; El-Bietar, J; Nelson, A; Willmering, MM; Grimley, M; Davies, SM; Towe, C; Woods, JC. Xenon-129 MRI detects ventilation deficits in paediatric stem cell transplant patients unable to perform spirometry. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2019; 53:1801779.

Walkup, LL; Thomen, RP; Akinyi, TG; Watters, E; Ruppert, K; Clancy, JP; Woods, JC; Cleveland, ZI. Feasibility, tolerability and safety of pediatric hyperpolarized 129Xe magnetic resonance imaging in healthy volunteers and children with cystic fibrosis. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2016; 46:1651-1662.

Haney, M; Ashraf, A; Lake, KE; Strecker, L; Myers, KC; Towe, C; Walkup, L; Woods, J; Edwards, SL; Cooper, R; Goldfarb, SB; Davies, SM; Koo, J; Groups, T. Community respiratory viruses are generally welltolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study. Haematologica: the hematology journal. 2025; 110:1882-1886.

Koo, J; Cooper, R; Edwards, SL; Lane, A; Loveless, SK; Strecker, L; Lake, KE; Myers, KC; Towe, C; Patti, J; Li, M; Goldfarb, SB; Woods, JC; Davies, SM. High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study. Pediatric Blood and Cancer. 2025; e31916.

Klimeš, F; Plummer, JW; Willmering, MM; Matheson, AM; Bdaiwi, AS; Gutberlet, M; Voskrebenzev, A; Wernz, MM; Wacker, F; Woods, J; Cleveland, ZI; Walkup, LL; Vogel-Claussen, J. Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study. Magnetic Resonance in Medicine. 2025; 93:1984-1998.

Walkup, LL; Roach, DJ; Plummer, JW; Willmering, MM; Zanette, B; Santyr, G; Fain, SB; Rock, MJ; Mata, J; Froh, D; Stanojevic, S; Cleveland, ZI; Ratjen, F; Woods, JC. Same-Day Repeatability and 28-Day Reproducibility of Xenon MRI Ventilation in Children With Cystic Fibrosis in a Multi-Site Trial. Journal of Magnetic Resonance Imaging. 2025; 61:1664-1674.

Bdaiwi, AS; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized 129Xenon MRI. Journal of Magnetic Resonance Imaging. 2025; 61:1860-1873.

Bdaiwi, AS; Willmering, MM; Plummer, JW; Hussain, R; Roach, DJ; Parra-Robles, J; Niedbalski, PJ; Woods, JC; Walkup, LL; Cleveland, ZI. 129Xe Image Processing Pipeline: An open-source, graphical user interface application for the analysis of hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2025; 93:1220-1237.

Willmering, MM; Albert, BJ; Plummer, JW; Greer, J; Walkup, LL; Lindquist, DM; Cleveland, ZI. A thermally polarized, dissolved-phase 129Xe phantom for quality-control and multisite comparisons of gas-exchange imaging. Journal of Magnetic Resonance. 2025; 371:107829.

Anderson, MA; Masokano, BI; Plummer, JW; Willmering, MM; Krivchenia, K; Towe, CT; Walkup, LL. Xe Ventilation and Gas-Exchange MRI Abnormalities in Children with Neuroendocrine Cell Hyperplasia of Infancy (NEHI). Pediatric Pulmonology. 2025; 60:e27410.

Soderlund, SA; Bdaiwi, AS; Plummer, JW; Woods, JC; Walkup, LL; Cleveland, ZI. Improved Diffusion-Weighted Hyperpolarized 129Xe Lung MRI with Patch-Based Higher-Order, Singular Value Decomposition Denoising. Academic Radiology. 2024; 31:5289-5299.

Plummer, JW; Hussain, R; Bdaiwi, AS; Soderlund, SA; Hoyos, X; Lanier, JM; Garrison, WJ; Parra-Robles, J; Willmering, MM; Niedbalski, PJ; Cleveland, ZI; Walkup, LL. A decay-modeled compressed sensing reconstruction approach for non-Cartesian hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2024; 92:1363-1375.

Plummer, JW; Hussain, R; Bdaiwi, AS; Costa, ML; Willmering, MM; Parra-Robles, J; Cleveland, ZI; Walkup, LL. Analytical corrections for B1-inhomogeneity and signal decay in multi-slice 2D spiral hyperpolarized 129Xe MRI using keyhole reconstruction. Magnetic Resonance in Medicine. 2024; 92:967-981.

Bdaiwi, AS; Svoboda, AM; Murdock, KE; Hendricks, A; Hossain, MM; Kramer, EL; Brewington, JJ; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying abnormal alveolar microstructure in cystic fibrosis lung disease via hyperpolarized 129Xe diffusion MRI. Journal of Cystic Fibrosis. 2024; 23:926-935.

Shanthikumar, S; Goldfarb, S; Abts, M; Barochia, A; Bergeron, A; Blinman, T; Bracken, J; Calvo, C; Casey, A; Charbek, E; Teusink-Cross, A; Towe, CT; Walkup, LL; Yanik, GA. Detection of Bronchiolitis Obliterans Syndrome after Pediatric Hematopoietic Stem Cell Transplantation: An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine. 2024; 210:262-280.

Ratjen, F; Stanojevic, S; Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Woods, J. 129 Response in imaging and lung function outcomes in the HyPOINT study. Journal of Cystic Fibrosis. 2023; 22:s68-s69.

Bdaiwi, AS; Costa, ML; Plummer, JW; Willmering, MM; Walkup, LL; Cleveland, ZI. B1 and magnetization decay correction for hyperpolarized 129 Xe lung imaging using sequential 2D spiral acquisitions. Magnetic Resonance in Medicine. 2023; 90:473-482.

Plummer, JW; Willmering, MM; Cleveland, ZI; Towe, C; Woods, JC; Walkup, LL. Childhood to adulthood: Accounting for age dependence in healthy-reference distributions in 129 Xe gas-exchange MRI. Magnetic Resonance in Medicine. 2023; 89:1117-1133.

Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Stanojevic, S; Ratjen, F; Woods, J. 165 Hyperpolarized xenon gas ventilation magnetic resonance imaging detects lung ventilation improvement in children with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor in a multisite study. Journal of Cystic Fibrosis. 2022; 21:s97.

Willmering, MM; Walkup, LL; Niedbalski, PJ; Wang, H; Wang, Z; Hysinger, EB; Myers, KC; Towe, CT; Driehuys, B; Cleveland, ZI; Woods, JC. Pediatric 129 Xe Gas-Transfer MRI-Feasibility and Applicability. Journal of Magnetic Resonance Imaging. 2022; 56:1207-1219.

Bdaiwi, AS; Niedbalski, PJ; Hossain, MM; Willmering, MM; Walkup, LL; Wang, H; Thomen, RP; Ruppert, K; Woods, JC; Cleveland, ZI. Improving hyperpolarized 129 Xe ADC mapping in pediatric and adult lungs with uncertainty propagation. NMR in Biomedicine. 2022; 35:e4639.

Roach, DJ; Willmering, MM; Plummer, JW; Walkup, LL; Zhang, Y; Hossain, MM; Cleveland, ZI; Woods, JC. Hyperpolarized 129Xenon MRI Ventilation Defect Quantification via Thresholding and Linear Binning in Multiple Pulmonary Diseases. Academic Radiology. 2022; 29 Suppl 2:S145-S155.

Walkup, LL; Myers, KC; Willmering, MM; Mehta, PA; Nelson, AS; Fleck, RJ; Woods, JC; Davies, SM; Towe, CT. Modern Lung Magnetic Resonance Imaging to Screen for Pulmonary Complications in Patients with Dyskeratosis Congenita. American Journal of Respiratory and Critical Care Medicine. 2021; 204:1340-1343.

Walkup, L; Roach, D; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Stanojevic, S; Ratjen, F; Woods, J. 537: 129Xe MRI is a repeatable measure of regional ventilation in children with stable CF. Journal of Cystic Fibrosis. 2021; 20:s253-s254.

Willmering, MM; Cleveland, ZI; Walkup, LL; Woods, JC. Removal of off-resonance xenon gas artifacts in pulmonary gas-transfer MRI. Magnetic Resonance in Medicine. 2021; 86:907-915.

Hahn, AD; Malkus, A; Kammerman, J; Higano, N; Walkup, LL; Woods, J; Fain, SB. Effects of neonatal lung abnormalities on parenchymal R2 * estimates. Journal of Magnetic Resonance Imaging. 2021; 53:1853-1861.

Lin, NY; Roach, DJ; Willmering, MM; Walkup, LL; Hossain, MM; Desirazu, P; Cleveland, ZI; Guilbert, TW; Woods, JC. 129Xe MRI as a measure of clinical disease severity for pediatric asthma. Journal of Allergy and Clinical Immunology. 2021; 147:2146-2153.e1.

Dournes, G; Walkup, LL; Benlala, I; Willmering, MM; Macey, J; Bui, S; Laurent, F; Woods, JC. The Clinical Use of Lung MRI in Cystic Fibrosis: What, Now, How?. Chest. 2021; 159:2205-2217.

Pennati, F; Walkup, LL; Chhabra, A; Towe, C; Myers, K; Aliverti, A; Woods, JC. Quantitative inspiratory-expiratory chest CT to evaluate pulmonary involvement in pediatric hematopoietic stem-cell transplantation patients. Pediatric Pulmonology. 2021; 56:1026-1035.

Willmering, MM; Roach, DJ; Kramer, EL; Walkup, LL; Cleveland, ZI; Woods, JC. Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis. Journal of Cystic Fibrosis. 2021; 20:533-539.