Walkup Lab

Publications

Ratjen, FA; Stanojevic, S; Munidasa, S; Roach, D; Mata, J; Froh, DK; Zanette, B; Santyr, G; Fain, SB; Rock, MJ; Walkup, LL; Woods, JC. Multicenter Study of Hyperpolarized Xenon Magnetic Resonance Imaging in Children with Cystic Fibrosis Following Initiation of Cystic Fibrosis Transmembrane Regulator Modulator Therapy (HyPOINT). Annals of the American Thoracic Society. 2025; 22(12):1891-1899.

Hussain, R; Bdaiwi, AS; Plummer, JW; Masokano, BI; Willmering, MM; Walkup, LL; Cleveland, ZI. Comparing Mean-anchored Generalized Linear Binning with Established Methods to Quantify Xenon-129 Ventilation Defect Percentage. Academic Radiology. 2025.

Bdaiwi, AS; Roach, DJ; West, ME; Willmering, MM; Daou, AW; Hossain, MM; Kramer, EL; Amin, R; Walkup, LL; Cleveland, ZI; Woods, JC. Longitudinal Monitoring of Lumacaftor/Ivacaftor Response in Young Children with Cystic Fibrosis Lung Disease Using 129Xe MRI. Academic Radiology. 2025; 32(10):6238-6249.

Matheson, AM; Bdaiwi, AS; Willmering, MM; Hysinger, EB; Mccormack, FX; Walkup, LL; Cleveland, ZI; Woods, JC. Disease Classification of Pulmonary Xenon Ventilation MRI Using Artificial Intelligence. Academic Radiology. 2025; 32(10):6330-6342.

Koo, J; Cooper, R; Edwards, SL; Lane, A; Loveless, SK; Strecker, L; Lake, KE; Myers, KC; Towe, C; Patti, J; Li, M; Goldfarb, SB; Woods, JC; Davies, SM. High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study. Pediatric Blood and Cancer. 2025; 72(10):e31916.

Hussain, R; Plummer, JW; Bdaiwi, AS; Willmering, MM; Kramer, EL; Walkup, LL; Cleveland, ZI. Optimizing Xenon 129 Ventilation MRI in Cystic Fibrosis with Spiral Imaging and Flip-Angle Correction. Radiology: Cardiothoracic Imaging. 2025; 7(5):e240574.

Haney, M; Ashraf, A; Lake, KE; Strecker, L; Myers, KC; Towe, C; Walkup, L; Woods, J; Edwards, SL; Cooper, R; Goldfarb, SB; Davies, SM; Koo, J; Groups, T. Community respiratory viruses are generally welltolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study. Haematologica. 2025; 110(8):1882-1886.

Klimeš, F; Plummer, JW; Willmering, MM; Matheson, AM; Bdaiwi, AS; Gutberlet, M; Voskrebenzev, A; Wernz, MM; Wacker, F; Woods, J; Cleveland, ZI; Walkup, LL; Vogel-Claussen, J. Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study. Magnetic Resonance in Medicine. 2025; 93(5):1984-1998.

Walkup, LL; Roach, DJ; Plummer, JW; Willmering, MM; Zanette, B; Santyr, G; Fain, SB; Rock, MJ; Mata, J; Froh, D; Stanojevic, S; Cleveland, ZI; Ratjen, F; Woods, JC. Same-Day Repeatability and 28-Day Reproducibility of Xenon MRI Ventilation in Children With Cystic Fibrosis in a Multi-Site Trial. Journal of Magnetic Resonance Imaging. 2025; 61(4):1664-1674.

Bdaiwi, AS; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized 129Xenon MRI. Journal of Magnetic Resonance Imaging. 2025; 61(4):1860-1873.

Bdaiwi, AS; Willmering, MM; Plummer, JW; Hussain, R; Roach, DJ; Parra-Robles, J; Niedbalski, PJ; Woods, JC; Walkup, LL; Cleveland, ZI. 129Xe Image Processing Pipeline: An open-source, graphical user interface application for the analysis of hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2025; 93(3):1220-1237.

Willmering, MM; Albert, BJ; Plummer, JW; Greer, J; Walkup, LL; Lindquist, DM; Cleveland, ZI. A thermally polarized, dissolved-phase 129Xe phantom for quality-control and multisite comparisons of gas-exchange imaging. Journal of Magnetic Resonance. 2025; 371:107829.

Anderson, MA; Masokano, BI; Plummer, JW; Willmering, MM; Krivchenia, K; Towe, CT; Walkup, LL. Xe Ventilation and Gas-Exchange MRI Abnormalities in Children with Neuroendocrine Cell Hyperplasia of Infancy (NEHI). Pediatric Pulmonology. 2025; 60(1):e27410.

Soderlund, SA; Bdaiwi, AS; Plummer, JW; Woods, JC; Walkup, LL; Cleveland, ZI. Improved Diffusion-Weighted Hyperpolarized 129Xe Lung MRI with Patch-Based Higher-Order, Singular Value Decomposition Denoising. Academic Radiology. 2024; 31(12):5289-5299.

Plummer, JW; Hussain, R; Bdaiwi, AS; Soderlund, SA; Hoyos, X; Lanier, JM; Garrison, WJ; Parra-Robles, J; Willmering, MM; Niedbalski, PJ; Cleveland, ZI; Walkup, LL. A decay-modeled compressed sensing reconstruction approach for non-Cartesian hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2024; 92(4):1363-1375.

Plummer, JW; Hussain, R; Bdaiwi, AS; Costa, ML; Willmering, MM; Parra-Robles, J; Cleveland, ZI; Walkup, LL. Analytical corrections for B1-inhomogeneity and signal decay in multi-slice 2D spiral hyperpolarized 129Xe MRI using keyhole reconstruction. Magnetic Resonance in Medicine. 2024; 92(3):967-981.

Bdaiwi, AS; Svoboda, AM; Murdock, KE; Hendricks, A; Hossain, MM; Kramer, EL; Brewington, JJ; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying abnormal alveolar microstructure in cystic fibrosis lung disease via hyperpolarized 129Xe diffusion MRI. Journal of Cystic Fibrosis. 2024; 23(5):926-935.

Shanthikumar, S; Gower, WA; Srinivasan, S; Rayment, JH; Robinson, PD; Bracken, J; Stone, A; Das, S; Barochia, A; Charbek, E; Liptzin, DR; Schultz, KR; Iyer, NP; Goldfarb, S. Detection of Bronchiolitis Obliterans Syndrome after Pediatric Hematopoietic Stem Cell Transplantation: An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine. 2024; 210(3):262-280.

Ratjen, F; Stanojevic, S; Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Woods, J. 129 Response in imaging and lung function outcomes in the HyPOINT study. Journal of Cystic Fibrosis. 2023; 22:s68-s69.

Bdaiwi, AS; Costa, ML; Plummer, JW; Willmering, MM; Walkup, LL; Cleveland, ZI. B1 and magnetization decay correction for hyperpolarized 129 Xe lung imaging using sequential 2D spiral acquisitions. Magnetic Resonance in Medicine. 2023; 90(2):473-482.

Plummer, JW; Willmering, MM; Cleveland, ZI; Towe, C; Woods, JC; Walkup, LL. Childhood to adulthood: Accounting for age dependence in healthy-reference distributions in 129 Xe gas-exchange MRI. Magnetic Resonance in Medicine. 2023; 89(3):1117-1133.

Willmering, MM; Walkup, LL; Niedbalski, PJ; Wang, H; Wang, Z; Hysinger, EB; Myers, KC; Towe, CT; Driehuys, B; Cleveland, ZI; Woods, JC. Pediatric 129 Xe Gas-Transfer MRI-Feasibility and Applicability. Journal of Magnetic Resonance Imaging. 2022; 56(4):1207-1219.

Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Stanojevic, S; Ratjen, F; Woods, J. 165 Hyperpolarized xenon gas ventilation magnetic resonance imaging detects lung ventilation improvement in children with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor in a multisite study. Journal of Cystic Fibrosis. 2022; 21:s97.

Bdaiwi, AS; Niedbalski, PJ; Hossain, MM; Willmering, MM; Walkup, LL; Wang, H; Thomen, RP; Ruppert, K; Woods, JC; Cleveland, ZI. Improving hyperpolarized 129 Xe ADC mapping in pediatric and adult lungs with uncertainty propagation. NMR in Biomedicine. 2022; 35(3):e4639.

Roach, DJ; Willmering, MM; Plummer, JW; Walkup, LL; Zhang, Y; Hossain, MM; Cleveland, ZI; Woods, JC. Hyperpolarized 129Xenon MRI Ventilation Defect Quantification via Thresholding and Linear Binning in Multiple Pulmonary Diseases. Academic Radiology. 2022; 29 Suppl 2(Suppl 2):S145-S155.