Cincinnati Children’s Ranked No. 3 Pediatric Cancer Program in U.S.

At Cincinnati Children’s, we are experts in treating and curing the hardest, most resistant cancers. That’s our mission and why families from across the world come to us to benefit from our expertise and the most advanced technologies. Our completely integrated approach to care and scientific discovery enables us to drive breakthroughs in medicine, develop new therapies, manage the most complex cancer diagnoses and be a top-ranked program in the nation.

We are accredited with commendation by the American College of Surgeons Commission on Cancer and ranked No. 3 by U.S. News & World Report.

Our inpatient pediatric cancer rehabilitation program is the first in the world to be accredited by the Commission on Accreditation of Rehabilitation (CARF).

But even more important than rankings, it’s our approach that helps deliver hope and healing for children and their families. That’s why we are often the first to develop the most advanced cancer therapies and technologies for children with relapsed and treatment-resistant conditions. It’s also why two-thirds of our patients come to Cincinnati Children’s for the hardest-to-treat cancers – refractory cancers that haven’t responded to traditional treatments or relapsed cancers that came back after initial treatments.

Personalized Care Is More Than a Promise – It’s Our Standard of Care

Every day, we’re pushing the boundaries of what medicine can do for children and families. One critical advancement in cancer care is the ability to tailor treatments to your child. Our researchers and oncologists work side by side to develop new ways to map the therapies that will help your child.

  • We develop new treatments for even the most difficult-to-treat cancers using “team science” that integrates our clinical and research laboratory teams. For example, research from our center led to the recent pediatric FDA approvals of the new drugs Vyxeos for acute myeloid leukemia and selumetinib for patients with inoperable neurofibromatosis tumors.
  • We were pioneers in the use of “next generation sequencing” to understand the genetic wiring of relapsed cancers and leukemias that have escaped traditional therapies. Then we tailor treatments to those cancers with new targeted drugs and immune therapies.
  • CAR T-cell therapy uses a patient’s own immune system to kill aggressive and treatment-resistant cancers. Our program is one of the most experienced in the country and with a comprehensive portfolio for leukemia and lymphoma, giving more children the opportunity to benefit from this life-saving therapy.
  • We are working to advance immune therapy in new clinical trials by combining it with radiation therapy to unmask cancer cells so that every last cancer cell can be eradicated.
  • We’re leading the field with advances in radiation therapy with the world’s first clinical trial of ultra-high-dose rate “FLASH” proton therapy. FLASH is a new technology that may reduce potential side effects and allow for an increased dose to better treat and potentially cure aggressive brain tumors, sarcomas, lymphomas and other cancers.

Hope Begins Here

Advances in cancer care mean that most children respond to traditional therapies. But when your child needs specialized care that goes beyond first-line treatments, our team delivers some of the most advanced, groundbreaking therapies in the world, which are often only available here, including:

  • Our research teams are actively developing new drugs designed specifically for children to better treat blood cancers, and brain and solid tumors.
  • Our specialized Bone Marrow Transplant Program has performed more than 2,200 pediatric marrow and stem cell transplants. The team helped develop stem cell transplant procedures that are the standard of care in more than 200 cancer centers throughout North America.
  • Researchers and clinicians are developing new uses of T-cell therapies to treat and prevent deadly viral infections in our immunocompromised cancer patients.
  • As a global leader in fertility preservation, we work to protect a patient’s ability to have biological children later in life. Our oncofertility center provides consults to every patient and has programs to preserve fertility in all ages from infancy to adulthood.
  • Our Proton Therapy Center with Pencil Beam Scanning delivers the most advanced form of radiation therapy available. This technology destroys cancer cells while minimizing damage to surrounding healthy tissues and organs and has fewer side effects to the brain. Our cancer researchers have begun the world’s first clinical trial of FLASH radiation therapy for cancer. FLASH uses proton radiation delivered at ultra-high speeds up to 100 times faster than what is used clinically today. Early research studies at Cincinnati Children’s and other centers around the world have investigated this novel technology and its effect on cancerous and healthy tissues in animals. This research suggests a lower incidence of side effects and potential to therefore use higher doses of radiation to better kill tumors.
  • Our “big data” researchers are analyzing millions of data points from clinical trials across the U.S. to develop new treatment options and better long-term outcomes for children and young adults.
  • Our Young Adult Cancer Center is internationally recognized as a pioneer in developing precision therapies for young adult patients. Based on our research, we’ve developed protocols to treat these patients who react to cancer therapies much differently than their younger and older counterparts
  • Our Cancer Survivorship Center provides specialized medical care and psychosocial support to childhood cancer survivors continuously and without interruption through adulthood.

Where Education Empowers

At Cincinnati Children's we offer education and empowerment through clear communication to navigate the confusing and emotional world of a cancer diagnosis.

That’s why we’ve pioneered new ways to put you at the center of information and help you confidently make decisions about treatments.

We’ve created communication that educates, engages and connects through:

  • Applications, websites and videos that put education and information at your fingertips – when, where and how you want it
  • Game-like “behavior reinforcers” that encourage and improve treatment adherence, like reminding and rewarding children to take medicine, eat healthy or stay active
  • Technology that monitors a child’s health and vital signs at home to give families peace of mind