Hematology - Hemangioma and Vascular Malformation
A Multicenter, Phase 2, Open-label Study Evaluating the Safety and Efficacy of Sirolimus 3.9% Topical Gel (PTX-022) in the Treatment of Microcystic Lymphatic Malformations
The main reason for this research study is to see if a new topical (applied to the skin) formulation of sirolimus, PTX-022, is safe and effective in treating microcystic lymphatic malformation, sometimes called blebs, on the skin. Sirolimus belongs to a group of medicines called mTOR inhibitors, wh ...More
Brain Vascular Malformation Consortium (BVMC) Project 2: Longitudinal Studies to Identify Biomarkers and Therapeutic Strategies for Sturge-Weber Syndrome
The purpose of this study is to learn more about Sturge-Weber Syndrome (SWS). By studying patients with SWS, we hope to understand how SWS vascular malformations lead to clinical symptoms, to identify which patients are at-risk for these symptoms, and to learn which treatment strategies could be pre ...More
Collection and Repository of Tissue Samples and Data from Patients with Tumors and Vascular Anomalies
By conducting these studies, researchers hope to learn more about and come up with better treatments for vascular anomalies. ...More
Hereditary Hemorrhagic Telangiectasia Patient Treatment Outcomes: A Retrospective and Prospective Patient Registry
In this research study we want to learn more about the presentation, treatment and progression of Hereditary Hemorrhagic Telangiectasia (HHT) in patients that are seen at Cincinnati Children's Hospital Medical Center (CCHMC). ...More
Identification of Biomarkers for Patients with Vascular Anomalies
While vascular anomalies are rare diseases, they can be life-threatening and devastating to affected patients and their families. Our understanding of vascular anomalies, and in turn their treatments, can be greatly improved if non-invasive biomarkers can be identified. The goal of this research stu ...More
Lymphatic Anomalies Registry
The goal of this research study is to better understand rare vascular tumors and malformations. There is little information available about the long-term effects of these lesions or the most effective treatments. We are conducting a research study to better understand these vascular lesions. We aim ...More
Rare Benign Vascular Tumor Registry
The purpose of this research study is to collect information on the natural course of benign vascular tumors and their response to treatment. This study data information may also be used to track the outcomes of various treatments, to determine which ones are the most helpful, and for future benign ...More
Contact Us
Adult Participants or Parents of Participants:
Cincinnati Children’s is involved in research because it is very important to understanding diseases and developing ways to prevent and treat health problems in children, as well as adults. Learn more about how you can help. Contact us at clinicalstudies@cchmc.org or 513-636-0098. Or, enroll in our database to be notified about future studies by completing an online sign up form.
Sponsors and Investigators:
The Office for Clinical and Translational Research at Cincinnati Children’s provides sponsors and investigators with comprehensive support services, research tools, personnel and facilities to conduct or facilitate pediatric and adult clinical research studies. Contact us at OCTR@cchmc.org or 513-636-0314.
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