At Cincinnati Children’s, we are committed to the discovery of new therapies and care protocols for children with liver disease. Research is critical to making this happen.

Our physicians and scientists conduct laboratory and clinical research to:

  • Identify new ways to prevent liver disease and provide early diagnosis and treatment
  • Develop new techniques to ensure the health of newly transplanted livers
  • Better understand how genetics affect a child’s outcome after a liver transplant

One area of cutting-edge liver research relates to our pursuit of alternative approaches to liver transplantation. These include tissue engineering techniques such as growing healthy livers in the lab for transplant, and saving failing livers by injecting them with healthy liver cells (rather than replacing them with a donor liver). Some of this research takes place at the new Center for Stem Cell & Organoid Medicine (CuSTOM) at Cincinnati Children’s, where scientists, clinicians and entrepreneurs are using advances in developmental biology, innovative stem cell technologies and miniature human organs, known as organoids, to accelerate discovery and develop new regenerative therapies.

Patient participation in research is critical to our mission of transforming medical care for children with end-stage liver disease. To learn about clinical liver research opportunities at Cincinnati Children’s, talk with your care team or contact the Pediatric Liver Care Center at 513-636-4415 and ask to speak with one of our research coordinators.