Liver Transplant Center

Meet the Team

The Liver Transplant Center is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. social workers, a pharmacist and a nutrition therapist to help provide our patients with the best care possible. Our team also includes Learn more about our faculty and staff.

Pediatric Hepatology

A photo of Akihiro Asai.

Akihiro Asai, MD, PhD 513-803-1791 akihiro.asai@cchmc.org

A photo of Akihiro Asai.

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Akihiro Asai, MD, PhD

Academic Affiliations

Instructor, UC Department of Pediatrics

Phone 513-803-1791

Email akihiro.asai@cchmc.org

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Clinical & Research Interests

Clinical

Pediatric hepatology; pediatric gastroenterology; pediatric liver transplantation

Research

Genetic and metabolic mechanism of pediatric liver diseases

Education and Training

MD: Nagoya University, Nagoya, Japan, 2003.

PhD: Tokyo University, Tokyo, Japan, 2008.

Residency: Pediatrics, Columbia University, New York, NY.

Certification: Pediatrics, 2010.

Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, Northwestern University, Chicago, IL.

Certification: Pediatric Gastroenterology, Hepatology and Nutrition, 2013.

Fellowship: Advanced/Transplant Hepatology, University of Cincinnati, Cincinnati, OH.

Certification: Advanced/Transplant Hepatology.

View PubMed Publications

Asai A, Kohli R. Familial homozygous hypercholesterolemia: When to turn to transplant? Pediatric Transplantation. 2015;19: 577–579.

Asai A, Miethke A, Bezerra J. Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes. Nat Rev Gastroenterol Hepatol. 2015 Jun;12(6):342-352.

Asai A, Malladi S, Misch J, Pan X, Malladi P, Diehl AM, Whitington PF. Elaboration of tubules with active Hedgehog drives parenchymal fibro genesis in gestational alloimmune liver disease. Human Pathology. 2015 Jan;46(1):84-93.

Asai A, Chou PM, Bu HF, Wang X, Rao MS, Jiang A, DiDonato CJ, Tan XD. Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice. Am J Physiol Gastrointest Liver Physiol. 2014 Mar;306(6):G496-504.

Wang X, Bu HF, Zhong W, Asai A, Zhou Z, Tan XD. MFG-E8 and HMGB1 are involved in the mechanism underlying alcohol-induced impairment of macrophage engulfing apoptotic cells. Mol Med. 2013 Jul 24;19:170-82.

Asai A, Sahani N, Kaneki M, Ouchi Y, Martyn JJ, Yasuhara S. Primary Role of Functional Ischemia, Quantitative Evidence of Two-Hit Mechanism, and Phosphodiesterase-5 Inhibitor Therapy in Mouse Muscular Dystrophy. PLoS One. 2007 Aug 29;2(8):e806.

Asai A, Sahani N, Ouchi Y, Martyn JJ, Yasuhara S. In vivo Micro-circulation Measurement in Skeletal Muscle by Intra-vital Microscopy. J Vis Exp. 2007;(4):210.

A photo of William Balisteri.

William F. Balistreri, MD Dorothy M. M. Kersten Professor of Pediatrics 513-636-4594 william.balistreri@cchmc.org

A photo of William Balisteri.

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William F. Balistreri, MD

Dorothy M. M. Kersten Professor of Pediatrics

Director Emeritus, Pediatric Liver Care Center

Medical Director Emeritus, Liver Transplantation

Program Director Emeritus, Fellowship in Transplant Hepatology

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-4594

Fax 513-636-7805

Email william.balistreri@cchmc.org

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Clinical Interests

Liver disease (cholestasis, viral hepatitis, metabolic liver disease; liver transplantation); celiac disease.

Through more than 550 publications, Balistreri has helped to clarify the understanding of many aspects of liver diseases in children.

Balistreri has been editor of The Journal of Pediatrics since 1995. He is the former editor-in-chief of the Journal of Pediatric Gastroenterology and Nutrition, and co-editor, associate editor, guest editor, reviewer and member of numerous editorial boards of several journals. He is co-editor of the prestigious text Liver Disease in Children.

In 2000, Balistreri became the first pediatrician to serve as president of the American Association for the Study of Liver Diseases. He has received numerous awards. These include the Distinguished Leadership Award from the CCFA; the Andrew Sass-Kortsak Memorial Award from the Canadian Liver Foundation and the Canadian Association for the Study of Liver; the Murray Davidson Award from the American Academy of Pediatrics; the prestigious Shwachman Award from the NASPGHAN; the Founder's Award, Cincinnati Pediatric Society; The Distinguished Alumnus Award, University of Buffalo; The Daniel Drake Medal, University of Cincinnati, College of Medicine; the Distinguished Service Award from AASLD; and the Distinguished Educator Award from the American Gastroenterological Association. He received the Outstanding Pediatrician award from the Ohio Chapter of the American Academy of Pediatrics for distinguished achievements in pediatric care and in the education of patients and physicians.

In 2012, NASPGHAN established the William F. Balistreri, MD, Prize for Excellence in Pediatric Gastroenterology, Hepatology and Nutrition. This award will recognize outstanding achievement in an area relevant to the field to be bestowed each year at the annual NASPGHAN meeting.

Balistreri joined Cincinnati Children's in 1978. He served as division director of Pediatric Gastroenterology, Hepatology, and Nutrition for 25 years.

Balistreri has been listed multiple times in Best Doctors in America.

Education and Training

BA: State University of New York at Buffalo, NY, 1966.

MD: University of Buffalo School of Medicine, NY, 1970.

Internship: Cincinnati Children's Hospital Medical Center (University of Cincinnati School of Medicine), Cincinnati, OH, 1970 to 1972.

Residency: Cincinnati Children's Hospital Medical Center (University of Cincinnati School of Medicine), Cincinnati, OH, 1971 to 1972.

Fellowship: Pediatric Gastroenterology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1973 to 1974.

Research Fellowship: Gastroenterology, Mayo Foundation, Mayo Clinic, Rochester, MN, 1973 to 1975.

Certification: Pediatrics, 1975 (renewed 1992); Pediatric Gastroenterology and Nutrition, 1990 (certificate #2; renewed 1997, 2004, and 2014).

Subspecialty Certification: 2006, American Board of Pediatrics (certificate #004 Pediatric Transplant Hepatology).

View PubMed Publications

Xanthakos SA, Podberesky DJ, Serai S, Miles L, King EC, Balistreri WF, Kohli R. Use of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease. The Journal of Pediatrics. 2014 Jan;164(1):186-8.

Balistreri WF, Master’s Perspective. Growth and Development of a New Subspecialty: Pediatric Hepatology. HEPATOLOGY. 2013;58:458-476.

Molleston JP, Mellman W, Narkewicz MR, Balistreri WF, Gonzalez-Peralta RP, Jonas M, Lobritto SJ, Mohan P, Murray KF, Rosenthal P, Robuck PR, Barton BA, Schwarz KB, Haber B for the PEDS-C Clinical Research Network. Auto-antibodies and Autoimmune Disease During Treatment of Children with Hepatitis C. J Pediatr Gastroenterol Nutr. 2013;56:304-310.

Jonas MM, Balistreri W, González-Peralta RP, Haber B, Lobritto S, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, Barton BA, Shepherd J, Robuck PR, Mitchell PD, Duggan C. Peginterferon for Chronic Hepatitis C in Children affects growth and body composition: Results from the Pediatric Study of Hepatitis C (PEDS-C) Trial. Hepatology. 2012 Aug;56(2):523-31.

Schwarz KB, Gonzalez-Peralta R, Murray K, Molleston J, Haber B, Jonas M, Mohan P, Balistreri W, Rosenthal P, Narkewicz M, Smith L, Robuck P, Barton B for the PEDS C Clinical Research Network. The combination of ribavirin and peginterferon is superior to perinterferon and placebo for Children and Adolescents with Chronic Hepatitis C: The Peds-C Trial. Gastroenterology. 2011;140:450-458.

Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, Tang PH, Miles L, Miles MV, Balistreri WF, Woods SC, Seeley RJ. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology. 2010 Sep;52(3):934-44.

Kohli R, Kirby M, Setchell KD, Jha P, Klustaitis K, Woollett LA, Pfluger PT, Balistreri WF, Tso P, Jandacek RJ, Woods SC, Heubi JE, Tschoep MH, D'Alessio DA, Shroyer NF, Seeley RJ. Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G652-60.

Kohli R, Boyd T, Lake K, Dietrich K, Nicholas L, Balistreri WF, Ebach D, Shashidhar H, Xanthakos SA. Rapid progression of NASH in childhood. J Pediatr Gastroenterol Nutr. 2010 Apr;50(4):453-6.

Leonis MA, Balistreri WF. Evaluation and management of end-stage liver disease in children. Gastroenterology. 2008 May;134(6):1741-51.

Ryckman FC, Bucuvalas JC, Nathan J, Alonso M, Tiao G, Balistreri WF. Outcomes following liver transplantation. Semin Pediatr Surg. 2008 May;17(2):123-30.

A photo of Jorge Bezerra.

Jorge A. Bezerra, MD Director, Division of Gastroenterology, Hepatology and Nutrition 513-636-3008 jorge.bezerra@cchmc.org

A photo of Jorge Bezerra.

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Jorge A. Bezerra, MD

Director, Division of Gastroenterology, Hepatology and Nutrition

Medical Director, Pediatric Liver Care Center

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-3008

Fax 513-636-5581

Email jorge.bezerra@cchmc.org

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Research Interests

Visit the Bezerra Lab.

Jorge A. Bezerra, MD, joined the Cincinnati Children's Hospital Medical Center Division of Gastroenterology, Hepatology and Nutrition in 1990, when he began his fellowship training in pediatric gastroenterology and nutrition and graduated in 1993.

From 1992-1994, Dr. Bezerra was a research scholar in the Division of Basic Sciences. He was appointed to the division in 1994 as an assistant professor within the UC Department of Pediatrics.

Dr. Bezerra completed his residency in pediatrics at the University of Arizona in Tucson, Arizona.

Dr. Bezerra has an active research career with his primary interests in molecular control of liver regeneration, biliary atresia, and genetic basis of intrahepatic cholestasis.

In addition to his research work, Dr. Bezerra is an active clinician for the outpatient GI clinical service and the inpatient liver service.

Education and Training

MD: Federal University Rio Grande Norte, Natal, Brazil, 1984.

Residency: University of Arizona, Tuscon, AZ, 1989.

Fellowship: Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 1994.

Certification: Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition.

View PubMed Publications

Bezerra JA. Biliary atresia in Brazil: where we are and where we are going. J Pediatr (Rio J). 2010 Nov-Dec;86(6):445-7.

Moyer K, Kaimal V, Pacheco C, Mourya R, Xu H, Shivakumar P, Chakraborty R, Rao M, Magee JC, Bove K, Aronow BJ, Jegga AG, Bezerra JA. Staging of biliary atresia at diagnosis by molecular profiling of the liver. Genome Med. 2010 May 13;2(5):33.

Kumar Mohanty S, Ivantes CA, Mourya R, Pacheco C, Bezerra JA. Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis via Mip2/Cxcl2. Pediatr Res. 2010 Jan 6.

Shivakumar P, Sabla GE, Whitington P, Chougnet CA, Bezerra JA. Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia. J Clin Invest. 2009 Aug;119(8):2281-90.

Shanmukhappa K, Matte U, Degen JL, Bezerra JA. Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair. J Biol Chem. 2009 May 8;284(19):12917-23.

Erickson N, Mohanty SK, Shivakumar P, Sabla G, Chakraborty R, Bezerra JA. Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia. Hepatology. 2008 May;47(5):1567-77.

Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, Stringer K, Caldwell C, Chougnet C, Bezerra JA. Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroenterology. 2007 Jul;133(1):268-77.

Liu C, Aronow BJ, Jegga AG, Wang N, Miethke A, Mourya R, Bezerra JA. Novel resequencing chip customized to diagnose mutations in patients with inherited syndromes of intrahepatic cholestasis. Gastroenterology. 2007 Jan;132(1):119-26.

Campbell KM, Arya G, Ryckman FC, Alonso M, Tiao G, Balistreri WF, Bezerra JA. High prevalence of alpha-1-antitrypsin heterozygosity in children with chronic liver disease. J Pediatr Gastroenterol Nutr. 2007 Jan;44(1):99-103.

Shanmukhappa K, Sabla GE, Degen JL, Bezerra JA. Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. BMC Gastroenterol. 2006 Nov 29;6:40.

A photo of John Bucuvalas.

John C. Bucuvalas, MD Attending Physician, Division of Gastroenterology, Hepatology and Nutrition 513-803-1791 john.bucuvalas@cchmc.org

A photo of John Bucuvalas.

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John C. Bucuvalas, MD

Attending Physician, Division of Gastroenterology, Hepatology and Nutrition

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-803-1791

Fax 513-636-7805

Email john.bucuvalas@cchmc.org

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Clinical & Research Interests

Clinical

Transplant hepatology

Research

Outcomes; operational tolerance in solid organ transplant recipients

Visit the Bucuvalas Lab.

Dr. Bucuvalas has a broad background in transplant hepatology. He has published broadly on outcomes following liver transplantation and am co-investigator for a study designed to study the Etiopathogenesis and clinical outcome for Medical Adherence in Liver Transplant Recipients. He serves as the protocol chair and have work closely with the PI, Dr. Sandy Feng, in parent study (Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients). He has established strong ties with pediatric solid organ transplant community both internal to Cincinnati Children's and external to Cincinnati Children's thru NIAID, ITN and CTOT. He also has strong ties and collaborations with the liver transplant community thru SPLIT, AST and UNOS.

Education and Training

AB: Harvard College, Cambridge, MA, 1974.

MD: Harvard Medical School, Boston, MA, 1978.

Residency: Pediatrics, Massachusetts General Hospital, Boston, MA, 1978 to 1981.

Chief Residency: Pediatrics, Massachusetts General Hospital, Boston, MA, 1981 to 1982.

Fellowship: Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1982 to 1986.

Research Scholar: Gastroenterology, Children's Hospital Research Foundation, Cincinnati, OH, 1985 to 1986.

Certification: Pediatrics, 1983; Pediatric Gastroenterology, 1990, re-certified, 1997, 2004; Transplant hepatology (CAQ), 2006.

View PubMed Publications

Gilroy R, Bucuvalas J. Share 35 has us too wary of strangers bearing gifts. Liver Transpl. 2016;22:159–160.

Goldstein SL, Kirkendall E, Nguyen H, Schaffzin JK, Bucuvalas J, Bracke T, Seid M, Ashby M, Foertmeyer N, Brunner L, Lesko A, Barclay C, Lannon C, Muething S. Electronic health record identification of nephrotoxin exposure and associated acute kidney injury. Pediatrics. 2013;132:e756-67.

Bucuvalas J, Filipovich L, Yazigi N, Narkewicz MR, Ng V, Belle SH, Zhang S, Squires RH. Immunophenotype predicts outcome in pediatric acute liver failure. J Pediatr Gastroenterol Nutr. 2013;56:311-5.

Englesbe RM, Kelly B, Goss J, Fecteau A, Mitchell J, Andrews W, Krapohl G, Magee J, Mazariegos G, Horslen S, Bucuvalas J. Reducing Pediatric Liver Transplant Complications: A Potential Roadmap for Transplant Quality Improvement Initiatives within North America. American Journal of Transplantation. 2012;12:2301-2306.

Ng VL, Alonso EM, Bucuvalas JC, et al. Health Status of Children Alive 10 Years after Pediatric Liver Transplantation Performed in the US and Canada: Report of the Studies of Pediatric Liver Transplantation Experience. J Pediatr. 2012;160:820-6.

Campbell K, Ng V, Martin S, Magee J, Goebel J, Anand R, Martz K, Bucuvalas J; SPLIT Renal Function Working Group. Glomerular filtration rate following pediatric liver transplantation--the SPLIT experience. Am J Transplant. 2010 Dec;10(12):2673-82.

Venkat V, Nick T, Wang Y, Bucuvalas JC. An Objective Measure to Identify Pediatric Liver Transplant Recipients at Risk for Late Allograft Rejection Related to Non-Adherence. Pediatric Transplantation. 2007;12:67-72.

Squires R, Shneider BL, Bucuvalas JC, Alonso E, Sokol RJ, Narkewicz MR et al. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006;148:652-8.

Bucuvalas JC, Frederick FC, Arya G, Andrew B, Lesko A, Cole C, James B, Kotagal U. A Novel Approach to Managing Variation Outpatient Therapeutic Monitoring of Calcineurin Inhibitor Blood Levels in Liver Transplant Recipients. J Pediatrics. 2005;146:744-750.

Bucuvalas JC, Britto M, Krug S, Ryckman FC, Atherton H, Alonso M, Balistreri and Kotagal U. Health-Related Quality Of Life In Pediatric Liver Transplant Recipients: A Single Center Study. Liver Transplantation. 2003;9:62-71.

A photo of Kathleen M. Campbell.

Kathleen M. Campbell, MD 513-636-4415 kathleen.campbell@cchmc.org

A photo of Kathleen M. Campbell.

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Kathleen M. Campbell, MD

Academic Affiliations

Associate Professor, UC Department of Pediatrics

Phone 513-636-4415

Fax 513-636-7805

Email kathleen.campbell@cchmc.org

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Clinical & Research Interests

Clinical

Diagnosis and management of pediatric liver disease, particularly biliary atresia and other forms of neonatal cholestasis; liver transplantation and post-transplant renal dysfunction.

Research

Clinical and genetic determinants of calcineurin inhibitor induced post-transplant nephrotoxicity; disease modifiers in biliary atresia

Kathleen M. Campbell, MD, joined the Division of Gastroenterology, Hepatology and Nutrition as a fellow in 2000, after completing her pediatric residency training at Cincinnati Children's Hospital Medical Center. Following the completion of her fellowship, she pursued an additional year of training in pediatric hepatology under the mentoring of Dr. William Balistreri and the physicians and surgeons of the Pediatric Liver Care Center, becoming one of the first in her specialty to obtain focused training in this field.

In 2004, Dr. Campbell was appointed assistant professor of pediatrics in the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center within the UC Department of Pediatrics. Her clinical and translational research interests include post-transplant renal dysfunction and genetic modifiers of disease in biliary atresia.

Education and Training

MD: University of Tennessee College of Medicine, Memphis, TN, 1997.

Residency: Pediatrics, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2000.

Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2003.

Advanced Fellowship: Pediatric Hepatology, University of Cincinnati and Cincinnati Children's Hospital Medical Center, 2004.

Certification: Pediatrics, 2000; Pediatric Gastroenterology, Hepatology and Nutrition, 2003.

View PubMed Publications

Campbell KM, Bucuvalas JC. Renal function in the long term after pediatric liver transplantation: is there a need for protocol kidney biopsies? Curr Opin Organ Transplant. 2010 Oct;15(5):608-13.

Choquette M, Goebel JW, Campbell KM. Nonimmune complications after transplantation. Pediatr Clin North Am. 2010 Apr;57(2):505-21, table of contents. Review.

Pacheco MC, Campbell KM, Bove KE. Ductal plate malformation-like arrays in early explants after a Kasai procedure are independent of splenic malformation complex (heterotaxy). Pediatr Dev Pathol. 2009 Sep-Oct;12(5):355-60.

Calvo-Garcia MA, Campbell KM, O'Hara SM, Khoury P, Mitsnefes MM, Strife CF. Acquired renal cysts after pediatric liver transplantation: association with cyclosporine and renal dysfunction. Pediatr Transplant. 2008 Sep;12(6):666-71.

Campbell KM, Arya G, Ryckman FC, Alonso M, Tiao G, Balistreri WF, Bezerra JA. High prevalence of alpha-1-antitrypsin heterozygosity in children with chronic liver disease. J Pediatr Gastroenterol Nutr. 2007 Jan;44(1):99-103.

Bucuvalas JC, Campbell KM, Cole CR, Guthery SL. Outcomes after liver transplantation: keep the end in mind. J Pediatr Gastroenterol Nutr. 2006 Jul;43 Suppl 1:S41-8.

Campbell KM, Yazigi N, Ryckman FC, Alonso M, Tiao G, Balistreri WF, Atherton H, Bucuvalas JC. High prevalence of renal dysfunction in long-term survivors after pediatric liver transplantation. J Pediatr. 2006 Apr;148(4):475-80.

Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, McNeal MM, Ward RL, Bezerra JA. Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J Clin Invest. 2004 Aug;114(3):322-9.

Campbell KM, Sabla GE, Bezerra JA. Transcriptional reprogramming in murine liver defines the physiologic consequences of biliary obstruction. J Hepatol. 2004 Jan;40(1):14-23.

Book Chapters

Campbell KM and Balistreri WF. Inflammatory Bowel Disease. Comprehensive Pediatrics. 1st edition. 2001.

A photo of James Heubi.

James E. Heubi, MD Director, Center for Clinical and Translational Science and Training 513-636-9776 sandra.geideman@cchmc.org

A photo of James Heubi.

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James E. Heubi, MD

Director, Center for Clinical and Translational Science and Training

Associate Dean, Clinical and Translational Research

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-9776

Fax 513-803-1039

Email sandra.geideman@cchmc.org

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Clinical & Research Interests

Clinical

Pediatric gastroenterology; hepatology and nutrition; pediatric cholestatic liver disease

Research

Pediatric cholestatic liver disease; childhood bone disease; fat malabsorption

James Heubi, MD, is associate dean for clinical and translational research and professor of pediatrics at the University of Cincinnati College of Medicine. He is the director of the Center for Clinical and Translational Science and Training which is the vehicle by which the University of Cincinnati, Cincinnati Children’s Hospital Medical Center and the Veterans Administration Medical Center administer the NIH-funded, Clinical Translational Science Award and director of the Division of Gastroenterology, Hepatology and Nutrition at the Cincinnati Children’s Hospital Medical Center.

He has been an active clinical investigator with over 195 peer reviewed publications and was the long term program director for the NIH funded General Clinical Research Center. He is the principal investigator and co-investigator on NIH grants and participates is a local principal or co-investigator on two rare disease networks supported by the NIH.

His research interests include cholestatic liver disease in childhood and its complications, inborn errors of bile acid metabolism, bone disease in gastrointestinal and hepatobiliary disorders, fat absorption, and cholesterol absorption and metabolism.

Education and Training

MD: Indiana University School of Medicine, Indianapolis, IN, 1973.

Residency: James Whitcomb Riley Hospital for Children, Indiana University, Indianapolis, IN, 1973 to 1975.

Fellowship: Pediatric Gastroenterology, Children's Hospital Medical Center, Cincinnati, OH, 1979.

Certification: Pediatric Gastroenterology and Nutrition, 1990.

View PubMed Publications

Heubi JE, Setchell KDR, Jha P, Buckley D, Zhang W, Rosenthal P, Potter C, Horslen S, Suskind D. Treatment of bile acid amidation defects with glycocholic acid. Hepatology. 2015 Jan;61(1):268-274.

Setchell KDR, Heubi JE, Shah S, Lavine JE, Suskind D, Al-Edreesi M, Potter C, Russell DW, O’Connell NC, Wolfe B, Jha P, Zhang W, Bove KE, Knisely AS, Hofmann AF, Rosenthal P, Bull LN. Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. Gastroenterology. 2013 May;144(5):945-955.

Gonzales E, Gerhardt MF, Fabre M, Setchell KDR, Davit-Spraul A, Vincent I, Heubi JE, Bernard O, Jacquemin E. Oral cholic acid for hereditary defects of primary bile acid synthesis: a safe and effective long-term therapy. Gastroenterology. 2009 Oct;137(4):1310-1320.

Setchell KDR, Heubi JE, Bove KE, O’Connell NC, Brewsaugh T, Steinberg SJ, Moser A, Squires Jr RH. Liver disease caused by failure to racemize trihydroxycholestanocic acid: gene mutation and effect of bile acid therapy. Gastroenterology. 2003 Jan;124(1):217-232.

Oelkers P, Kirby LC, Heubi JE, Dawson PA. Primary bile acid malabsorption caused by mutations in the ileal sodi¬um-de¬pen¬dent bile acid transporter gene (SLC10A2). J Clin Invest. 1997 Apr 15;99(8):1880-1887.

Heubi JE, Hollis BW, Specker B, Tsang RC. Bone disease in chronic childhood cholestasis I. Vitamin D absorption and metabolism. Hepatology. 1989 Feb;9(2):258-264.

Setchell KDR, Suchy FJ, Welsh MB, Zimmer-Nechemias L, Heubi JE, Balistreri WF. Δ4-3-Oxosteroid 5B-reductase deficiency described in identical twins with neonatal hepatitis - A new inborn error in bile acid synthesis. J Clin Invest. 1988 Dec; 82(6):2148-2157.

Heubi JE, Daugherty CC, Partin JS, Partin JC, Schubert WK. Grade l Reye's Syndrome--outcome and predictors of progression to deeper coma grades. N Engl J Med. 1984 Dec 13;311(24):l539-1554.

Lichtenstein PK, Heubi JE, Daugherty CC, Farrell MK, Sokol RJ, Rothbaum RJ, Suchy FJ, Balistreri WF. Grade l Reye's Syndrome. A frequent cause of vomiting and liver dysfunction following varicella and upper respiratory tract infection. N Engl J Med. 1983 Jul;309(3):l33-139.

Heubi JE, Balistreri WF, Fondacaro JD, Partin JC, Schubert WK. Primary bile acid malabsorption: Defective in vitro ileal active bile acid transport. Gastroenterology. 1982 Oct;83(4):804-8ll.

Cincinnati Center for Clinical and Translational Science and Training. Principal Investigator. National Center for Advancing Translational Sciences/National Institutes of Health. Aug 2015-Mar 2019. UL1 TR000077-05.

Pediatric Gastroenterology and Nutrition Training Grant. Mentor. National Institute of Diabetes and Digestive and Kidney Diseases/ National Institutes of Health. Jul 2005-Jun 2020. T32 DK007727.

Clinical Center of Cholestatic Liver Disease in Children (CHILDREN). Co-Investigator. National Institute of Diabetes and Digestive and Kidney Diseases/ National Institutes of Health. Sep 2009-May 2019. U01 DK062497.

Sterol and Isoprenoid Diseases Consortium. Site Principal Investigator. Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health. Sep 2009-Jul 2019. U54 HD061939.

Bone Mineral Accretion in Young Children. Co-Investigator. Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health. Sep 2013-Jul 2018. R01 HD076321.

Short Term Medical Student Training Grant. Principal Investigator. National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health. Apr 2002-Mar 2019. T35 DK060444-11.

A photo of Samuel Kocoshis.

Samuel A. Kocoshis, MD Medical Director, Intestinal Care Center 513-636-4415 samuel.kocoshis@cchmc.org

A photo of Samuel Kocoshis.

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Samuel A. Kocoshis, MD

Medical Director, Intestinal Care Center

Medical Director, Small Bowel Transplantation Program

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-4415

Fax 513-636-7805

Email samuel.kocoshis@cchmc.org

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Clinical & Research Interests

Clinical

Management of complex intestinal and liver disease; small bowel transplantation; general disorders of the gastrointestinal tract

Research

Altered bile acid metabolism in gastrointestinal disease; small bowel transplantation; inflammatory bowel disease; short bowel syndrome

Samuel Kocoshis, MD, is an expert in the management of complex intestinal and liver disease at Cincinnati Children's Hospital Medical Center.

Dr. Kocoshis is the director of the Pediatric Nutrition and Intestinal Care Center in the Division of Gastroenterology, Hepatology and Nutrition, and is also the medical director of the Small Intestinal Transplantation Program. In addition, he is professor of pediatrics at the University of Cincinnati College of Medicine.

Dr. Kocoshis' long-standing research interest has been altered bile acid metabolism in gastrointestinal disease. His current clinical research program focuses upon intestinal adaptation following massive small intestinal resection, as well as the immunology of intestinal transplantation.

Prior to joining Cincinnati Children's, Dr. Kocoshis was chief of Pediatric Gastroenterology and co-director of the Intestinal Care Center at Children's Hospital of Pittsburgh, and professor of pediatrics at the University of Pittsburgh School of Medicine.

Dr. Kocoshis earned his bachelor's degree from DePauw University and his medical degree from the Medical College of Wisconsin. He completed an internship in pediatrics at the West Virginia University Medical Center; a residency in pediatrics at Children's Hospital of Pittsburgh; and a clinical fellowship in gastroenterology at Yale University School of Medicine.

Education and Training

BS: DePauw University, Greencastle, IN.

MD: Medical College of Wisconsin, Milwaukee, WI.

Residency: Children's Hospital of Pittsburgh, Pittsburgh, PA.

Fellowship: Yale University School of Medicine, New Haven, CT.

View PubMed Publications

Kocoshis SA. Medical management of pediatric intestinal failure. Semin Pediatr Surg. 2010 Feb;19(1):20-6. Review.

Wessel JJ, Kocoshis SA. Nutritional management of infants with short bowel syndrome. Semin Perinatol. 2007 Apr;31(2):104-11. Review.

Nathan JD, Rudolph JA, Kocoshis SA, Alonso MH, Ryckman FC, Tiao GM. Isolated liver and multivisceral transplantation for total parenteral nutrition-related end-stage liver disease. J Pediatr Surg. 2007 Jan;42(1):143-7.

Kocoshis S. Small Intestinal Failure in Children. Curr Treat Options Gastroenterol. 2001 Oct;4(5):423-432.

A photo of Alexander Miethke.

Alexander G. Miethke, MD Medical Director, Liver Transplant Program 513-636-8948 alexander.miethke@cchmc.org

A photo of Alexander Miethke.

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Alexander G. Miethke, MD

Medical Director, Liver Transplant Program

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-8948

Email alexander.miethke@cchmc.org

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Clinical & Research Interests

Clinical

Pediatric liver disease including biliary atresia, inherited liver diseases, autoimmune hepatitis, and primary sclerosing cholangitis; gastrointestinal problems in children with bone marrow failure syndromes

Research

Immune mediated liver injury, specifically the role of regulatory T cells in biliary atresia and primary sclerosing cholangitis; genetic basis for intrahepatic cholestasis in children; acute liver failure in infants with mitochondrial disorders

Alexander G. Miethke, MD, joined the Division of Gastroenterology, Hepatology and Nutrition as a fellow in 2005, after completing his Pediatric Residency Training at Cincinnati Children's Hospital Medical Center. Following the completion of his fellowship, he pursued an additional year of training in pediatric transplant hepatology under the mentorship of Dr. William Balistreri and the physicians and surgeons of the Pediatric Liver Care Center.

In 2009, Dr. Miethke was appointed assistant professor of pediatrics in the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center at Cincinnati Children's within the UC Department of Pediatrics. His basic science research interests include the role of regulatory T cells in biliary atresia and other immune mediated liver diseases and the genetic basis of chronic cholestasis syndromes.

Education and Training

MD: Humboldt-University, Berlin, Germany, 2000.

Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2002-2004.

Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2005-2007.

Advanced Fellowship: Pediatric Transplant Hepatology, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009.

Certification: Pediatrics, 2005; Pediatric Gastroenterology, 2009; Pediatric Transplant Hepatology, 2010.

View PubMed Publications

Evason K, Bove KE, Finegold MJ, Knisely AS, Rhee S, Rosenthal P, Miethke AG, Karpen SJ, Ferrell LD, Kim GE. Morphologic findings in progressive familial intrahepatic cholestasis 2 (PFIC2): correlation with genetic and immunohistochemical studies. Am J Surg Pathol. 2011;35:687-96.

Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, Chougnet CA. Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia. J Hepatol. 2010 May;52(5):718-26.

Liu C, Aronow BJ, Jegga AG, Wang N, Miethke A, Mourya R, Bezerra JA. Novel resequencing chip customized to diagnose mutations in patients with inherited syndromes of intrahepatic cholestasis. Gastroenterology. 2007 Jan;132(1):119-26.

Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, McNeal MM, Ward RL, Bezerra JA. Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J Clin Invest. 2004 Aug;114(3):322-9.

Amy E. Taylor, MD 513-636-4415 amy.taylor@cchmc.org

Pediatric Hepatobiliary Surgery

A photo of Maria Alonso.

Maria H. Alonso, MD Co-Surgical Director, Intestinal Transplant Surgery 513-636-4371 maria.alonso@cchmc.org

A photo of Alexander Bondoc.

Alexander J. Bondoc, MD 513-636-4371 alex.bondoc@cchmc.org

A photo of Alexander Bondoc.

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Alexander J. Bondoc, MD

Academic Affiliations

Assistant Professor, UC Department of Surgery

UC Department of Pediatrics

Phone 513-636-4371

Email alex.bondoc@cchmc.org

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Research Interests

Liver; kidney transplantation; hepatobiliary surgery; minimally invasive surgery

Education and Training

MD: University of Michigan, Ann Arbor, MI, 2005.

AB: English Literature, Georgetown University, Washington, DC, 2001.

Residency: University of Cincinnati, Cincinnati, OH, 2005-2012; Research Assistant, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, MI, 2002-2005.

Fellowships: Research Fellow, Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2007-2009; Pediatric Surgery Fellow, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2012-2014; Abdominal Transplant Surgery Fellow, University of Cincinnati, College of Medicine, Cincinnati, OH, 2014-2016.

Certification: Pediatric Surgeon, 2014; Transplant Surgeon, 2016.

View PubMed Publications

Knod JL, Bondoc AJ, Garrison AP, Bischoff A, Dickie B, Frischer JS. Concurrent esophageal atresia with tracheoesophageal fistula and Hirschsprung disease. J Pediatr Surg Case Rep. 2015;3:499-500.

Bondoc A, Tiao G. Chronic Pancreatitis in the Pediatric Population. In: Operative Pediatric Surgery, 2nd Edition. March, 2014.

Mohanty SK, Donnelly B, Bondoc A, Jafri M, Walther A, Coots A, McNeal M, Witte D, Tiao GM. Rotavirus replication in the cholangiocyte mediates the temporal dependence of murine biliary atresia. PLoS One. 2013 Jul 3;8(7):e69069.

Bondoc AJ, Taylor JA, Alonso MH, Nathan JD, Wang Y, Balistreri W, Ryckman FC, Tiao, GM. The beneficial impact of revision of Kasai portoenterostomy for biliary atresia: an institutional study. Ann Surg. 2012;255:570-6.

Wang W, Donnelly B, Bondoc A, Mohanty SK, McNeal M, Ward R, Sestak K, Zheng S, Tiao GM. The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice. J Virol. 2011;85:9069-77.

Bondoc A, Jafri M, Donnelly B, Mohanty S, McNeal M, Ward R, Tiao G. Prevention of the murine model of biliary atresia following live rotavirus vaccination of dams. J Pediatr Surg. 2009:44;1479-90.

Jafri M, Donnelly B, Bondoc A, Allen S, McNeal M, Ward R, Tiao G. Cholangiocyte secretion of chemokines in experimental biliary atresia. J Pediatr Surg. 2009;44:500-7.

Jafri M, Donnelly B, Allen S, Bondoc A, McNeal M, Rennert PD, Weinreb PH, Ward R, Tiao G. Cholangiocyte expression of α2β1 integrin confers susceptibility to rotavirus infection in experimental biliary atresia. Am J Physiol Gastrointest Liver Physiol. 2008;295:G16-26.

Bondoc AJ. Peripheral Vascular Disease. In: The Mont Reid Surgical Handbook, 6th Edition. August, 2008.

Bondoc AJ. Carotid Disease. In: The Mont Reid Surgical Handbook, 6th Edition. August, 2008.

Bondoc AJ. Sepsis and Surgical Infection. In: The Mont Reid Surgical Handbook, 6th Edition. August, 2008.

A photo of Jaimie Nathan.

Jaimie D. Nathan, MD Surgical Director, Pancreas Care Center 513-636-4371 jaimie.nathan@cchmc.org

A photo of Jaimie Nathan.

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Jaimie D. Nathan, MD

Surgical Director, Pancreas Care Center

Surgical Director, Kidney and Intestinal Transplant Programs

Associate Surgical Director, Liver Transplant Program

Academic Affiliations

Associate Professor, UC Department of Surgery

UC Department of Pediatrics

Phone 513-636-4371

Fax 513-636-7657

Email jaimie.nathan@cchmc.org

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Clinical Interests

Hepatobiliary and pancreatic disease; liver, kidney, and intestinal transplantation; pediatric surgical oncology; neonatal surgery; minimally invasive surgery

Education and Training

BS: Yale University, New Haven, CT, 1993.

MD: Yale University, New Haven, CT, 1998.

Residency: General Surgery, Duke University Medical Center, Durham, NC, 1998-2000 and 2002-2005.

Surgical Research Fellowship: Duke University Medical Center, Durham, NC, 2000-2002.

Pediatric Surgery Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2005-2007.

Transplant Surgery Fellowship: University of Cincinnati, Cincinnati, OH, 2007-2009.

Certification: American Board of Surgery, General Surgery, 2007; American Board of Surgery, Pediatric Surgery, 2008; American Society of Transplant Surgeons Certification, 2009.

View PubMed Publications

Szabo FK, Hornung L, Oparaji JA, Alhosh R, Husain SZ, Liu QY, Palermo J, Lin TK, Nathan JD, Podberesky DJ, Lowe M, Fei L, Abu-El-Haija M. A prognostic tool to predict severe acute pancreatitis in pediatrics. Pancreatology. 2016;16:358-364.

Lin TK, Palermo JJ, Nathan JD, Tiao GM, Hornung LN, Fei L, Abu-El-Haija M. Timing of cholecystectomy in children with biliary pancreatitis. J Pediatr Gastroenterol Nutr. 2016;62:118-121.

Walther AE, Coots AC, Goebel JW, Alonso MH, Ryckman FC, Tiao GM, Nathan JD. Laparoscopic donor nephrectomy for the pediatric recipient population: risk factors for adverse outcomes. Pediatr Transplant. 2015;19:836-843.

Galloway D, Danziger-Isakov L, Goldschmidt M, Hemmelgarn T, Courter J, Nathan JD, Alonso M, Tiao G, Fei L, Kocoshis S. Incidence of bloodstream infections in small bowel transplant recipients receiving selective decontamination of the digestive tract: a single center experience. Pediatr Transplant. 2015;19:722-729.

Goldschmidt ML, Kocoshis SA, Tiao GM, Alonso MH, Nathan JD. Limited surgical resection for graft salvage following recovery from complicated exfoliative rejection in pediatric intestinal recipients. Pediatr Transplant. 2015;19:E170-176.

Ubesie AC, Cole CR, Nathan JD, Tiao GM, Alonso MH, Mezoff AG, Henderson CJ, Kocoshis SA. Micronutrient deficiencies in pediatric and young adult intestinal transplant patients. Pediatr Transplant. 2013;17:638-645.

Jensen MK, Campbell KM, Alonso MH, Nathan JD, Ryckman FC, Tiao GM. Management and long-term consequences of portal vein thrombosis after liver transplantation in children. Liver Transpl. 2013;19:315-321.

Bondoc AJ, Taylor JA, Alonso MH, Nathan JD, Wang Y, Balistreri WF, Bezerra JA, Ryckman FC, Tiao GM. The beneficial impact of revision of Kasai portoenterostomy for biliary atresia: an institutional study. Ann Surg. 2012 Mar;255(3):570-576.

Shin CR, Nathan J, Alonso M, Yazigi N, Kocoshis S, Tiao G, Davies SM. Incidence of acute and chronic graft-versus-host disease and donor T-cell chimerism after small bowel or combined organ transplantation. J Pediatr Surg. 2011 Sep;46(9):1732-1738.

Nathan JD, Rudolph JA, Kocoshis SA, Alonso MH, Ryckman FC, Tiao GM. Isolated liver and multivisceral transplantation for total parenteral nutrition-related end-stage liver disease. J Pediatr Surg. 2007 Jan;42(1):143-7.

A photo of Gregory Tiao.

Greg M. Tiao, MD Director, Division of General and Thoracic Surgery 513-636-4371 greg.tiao@cchmc.org

A photo of Gregory Tiao.

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Greg M. Tiao, MD

Director, Division of General and Thoracic Surgery

Frederick C. Ryckman Chair in Pediatric Surgery

Surgical Director, Liver Transplantation

Associate Director, Pediatric Surgery Fellowship

Academic Affiliations

Professor, UC Department of Surgery

UC Department of Pediatrics

Phone 513-636-4371

Fax 513-636-7657

Email greg.tiao@cchmc.org

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Clinical Interests

Biliary atresia

As a pediatric surgeon and a transplant surgeon, Dr. Tiao is involved in the care of children afflicted with biliary atresia from the time of presentation and diagnosis to the initial Kasai portoenterostomy to the liver transplant, when necessary. He sees the many challenges children and their families experience when diagnosed with this life threatening disease process. From that perspective, defining the basis of this disease process such that therapeutic strategies can be developed eliminating these complex interventions is his career goal. His short term goal is to develop an independent research laboratory investigating the pathogenesis of virus induced biliary atresia specifically seeking to determine the mechanistic basis of this disease so that new treatment strategies can be developed to salvage the native liver.

Dr. Tiao's overarching hypothesis is that biliary atresia results from the infection of cholangiocytes by a virus triggering immune-mediated biliary obstruction. His focus is to determine the mechanisms used by RRV to infect cholangiocytes, how RRV undergoes replication within the cholangiocyte, and how infected cholangiocytes modify the microenvironment, activating the immune system resulting in biliary obstruction. Determination of the mechanistic basis of these inter-related events is essential to understanding the pathogenesis of virus induced BA. By focusing on the basis for the viral insult in the initiation of biliary atresia, he has defined an area of independence from Dr. Jorge Bezerra, his primary research mentor.

Education and Training

BS: Northwestern University, Evanston, IL, 1986.

MD: University of Illinois, Chicago, IL, 1990.

Residency: Loyola University, Maywood, IL, 1991-1992; Senior Resident, Department of Surgery, University of Cincinnati, Cincinnati, OH, 1995-1997; Chief Resident, Department of Surgery, University of Cincinnati, Cincinnati, OH, 1997-1998.

Fellowships: Research Fellow, University of Cincinnati, Cincinnati, OH, 1992-1995; Transplant Surgery Fellow, University of Cincinnati, Cincinnati, OH, 2000-2002; Pediatric Surgery Fellow, Los Angeles Children's Hospital, Los Angeles, CA, 1998-2000.

Certification: Pediatric Surgeon, 2000; Transplant Surgeon, 2002.

Coots A, Donnelly B, Mohanty S, Tiao G. Rotavirus Infection of Human Cholangiocytes Parallels the Murine Model of Biliary Atresia. J Surg Res. 2012 Oct;177(2):275-81. 2012.

Meyers RL, Tiao GM, Dunn SP, Langham Jr, MR. Liver transplantation in the management of unresectable hepatoblastoma in children. Front Biosci (Elite Ed). 2012 Jan;E4:1293-302.

Shin CR, Nathan J, Alonso M, Yazigi N, Kocoshis S, Tiao G, Davies SM. Incidence of acute and chronic graft-versus-host disease and donor T-cell chimerism after small bowel or combined organ transplantation. J Pediatr Surg. 2011;46:1732-8.

Fernandez KS, Baum R, Fung B, Yeager N, Leonis MA, Wagner LM, Tiao G, Ross ME. Chemoresistant Hepatoblastoma in a Patient with Mosaic Trisomy 18 Treated with Orthotopic Liver Transplantation. Peditr Blood Cancer. 2011;56:498-500.

Superina R, Magee J, Brandt M, Healey P, Tiao G, Ryckman F, Karrer F, Iyer K, Fecteau A, West K, Burns R, Flake A, Hammin L, Lowell J, Dillon P, Columbani P, Ricketts R, Yun L, Moore J, Kasper W. Childhood Liver Research and Education Network. AnnSurg. 2011.

Bondoc A, Taylor J, Alonso M, Nathan, J, Wang Y, Balistreri W, Bezerra J, Ryckman F, Tiao G. The Beneficial Impact of Revision of Kasai Portoenterostomy for Biliary Atresia: An Institutional Study. AnnSurg. 2012;255(3):570-6.

Wang W, Donnelly B, Bondoc A, Mohanty SK, McNeal M, Ward R, Sestak K, Zheng S, Tiao G. The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice. J Virol. 2011 Sep;85(17):9069-77.

Jafri M, Donnelly B, Bondoc A, Allen S, Tiao G. Cholangiocyte secretion of chemokines in experimental biliary atresia. J Pediatr Surg. 2009;44(3):500-7.

Bondoc AJ, Jafri MA, Donnelly B, Mohanty SK, McNeal MM, Ward, RL, Tiao GM. Prevention of the murine model of biliary atresia after live rotavirus vaccination of dams. J Pediatr Surg. 2009;44(8):1479-90.

The Molecular Determinants of Virus Induced Biliary Induced Biliary Asteria. Principal Investigator. Apr 2011-Mar 2016.

Nycomed Liver Trial. Principal Investigator. 2012-present.TC-2402-040-SP.

Multidisciplinary Team

A photo of Katherine K. Bedard-Thomas.

Katherine K. Bedard-Thomas, PhD Staff Psychologist II, Division of Behavioral Medicine and Clinical Psychology 513-517-1046 katherine.bedard@cchmc.org

Lisa Belle, MSW, LSW Social Worker II, Liver Transplant Center 513-636-9097 lisa.belle@cchmc.org

Siobahn M. Cooper, APRN, CPNP Nurse Practitioner, Division of Gastroenterology, Hepatology and Nutrition 513-803-7472 siobhan.cooper@cchmc.org

Jodi Engelhardt, RN Liver Transplant Coordinator, Liver Transplant Center 513-636-4955 jodi.engelhardt@cchmc.org

Laura Hatcher, APRN, CNP Nurse Practitioner, Division of Gastroenterology, Hepatology and Nutrition 513-636-4415 laura.hatcher@cchmc.org

Sarah Myers, RN Liver Transplant Coordinator, Liver Transplant Center 513-636-4955 sarah.myers@cchmc.org

Melissa Nichols, RN Liver Transplant Coordinator, Liver Transplant Center 513-636-4955 melissa.nichols@cchmc.org

Rebecca L. Rengering, RN, BSN, CPN Clinical Manager, Renal/Liver Transplant 513-636-4955 becky.rengering@cchmc.org

A photo of Kristin Loiselle.

Kristin Loiselle Rich, PhD Pediatric Psychologist, Division of Behavioral Medicine and Clinical Psychology 513-636-4336 kristin.loiselle@cchmc.org

A photo of Kristin Loiselle.

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Kristin Loiselle Rich, PhD

Pediatric Psychologist, Division of Behavioral Medicine and Clinical Psychology

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4336

Email kristin.loiselle@cchmc.org

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Clinical & Research Interests

Clinical

Pediatric psychology; coping with chronic illness; adherence to treatment/self-management; transition of responsibility for health care; behavioral pain management; solid organ transplant; cognitive-behavioral therapy

Research

Adherence to medical regimens; dissemination and implementation of evidence-based behavioral interventions; quality of life

Kristin Loiselle Rich, PhD joined the Division of Behavioral Medicine and Clinical Psychology as an assistant professor of Pediatrics at the University of Cincinnati College of Medicine after completing her postdoctoral fellowship in the Center for Treatment Adherence and Self-Management at Cincinnati Children's.

During graduate school and fellowship, Dr. Rich has focused on identifying factors related to adherence to prescribed medical regimens, as well as trajectories of health-related quality of life among children with various chronic medical conditions. During fellowship, Dr. Rich was involved with a hospital-based initiative to implement a system for assessing barriers to medication adherence, using the latest technology to monitor adherence, and bring behavioral interventions to improve adherence to the bedside. She is looking forward to helping spread this system to other medical divisions at Cincinnati Children's.

Dr. Rich also provides outpatient treatment for children with various medical conditions, including kidney, rheumatologic, and pancreatic disease, as well as non-pharmacological treatment for chronic pain. She also conducts psychosocial evaluations for children who are being evaluated for a solid organ transplant.

Education and Training

PhD: University of Georgia, Athens, GA, 2014.

Residency: O'Grady Residency in Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2013-2014.

Fellowship: Behavioral Medicine and Clinical Psychology/Center for Treatment Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2014-2016.

View PubMed Publications

Julie Sheehan, MSW, LSW Social Worker, Liver Transplant Center 513-803-8974 julie.brunsman@cchmc.org

A photo of Shalonda Slater.

Shalonda K. Slater, PhD Pediatric Psychologist, Clinical, Behavioral Medicine and Clinical Psychology 513-636-4336 shalonda.slater@cchmc.org

A photo of Shalonda Slater.

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Shalonda K. Slater, PhD

Pediatric Psychologist, Clinical, Behavioral Medicine and Clinical Psychology

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4336

Fax 513-636-7756

Email shalonda.slater@cchmc.org

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Clinical & Research Interests

Clinical

Behavioral pain management; coping with chronic illness; psychosocial adjustment to transplant

Research

Family adjustment to chronic illness; child adjustment to chronic pain

Shalonda K. Slater, PhD, is an assistant professor in the Department of Pediatrics at Cincinnati Children’s Hospital Medical Center within the UC Department of Pediatrics.

She provides clinical care for children with chronic pain including children with headache, sickle cell disease and children awaiting transplantation. She is also a consultant for a NIH-funded pediatric chronic headache clinical trial which involves implementing a cognitive-behavioral-based intervention which focuses on coping and adherence.

She is a member of the Pain Quality Improvement team, part of a hospital-wide initiative aimed at integrating quality improvement science.

Education and Training

PhD: University of Florida, Gainesville, FL, 2007.

Internship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certification: Licensed Psychologist.

View PubMed Publications

Jennifer L. Staley-Haynes, BSN, RN Liver Transplant Coordinator, Liver Transplant Center 513-636-4955 jennifer.staley-haynes@cchmc.org

Megan Watts, RN Liver Transplant Coordinator, Liver Transplant Center 513-636-4955 megan.watts@cchmc.org

Renee A. Wieman, RD, CNSC Registered Dietitian III, Liver Transplant Center 513-636-3196 renee.wieman@ccmc.org

Program Manager

Jenny Carmichael RN, BSN, CPN

Living Related Donor Coordinators

Marty Hudson MA, RN
Laura Mooney RN, BSN, CPN

Pharmacist

Sarah Stiehl, PharmD

Transplant Financial Counselor

Carol Page RN, MSN
Karen Russell RN, BSN, CCM

Chaplain

Rev. Salvador Leavitt-Alcántara

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