The Retinoblastoma Program at Cincinnati Children’s offers a broad array of leading-edge therapies when providing retinoblastoma treatment. They include:

  • Surgery
  • Procedures designed to shrink the tumor without damaging healthy tissue. These include laser photocoagulation (a type of laser surgery), cryotherapy (cold therapy) and thermotherapy (heat therapy) 
  • Subconjunctival-directed chemotherapy (chemotherapy delivered directly to the front of the eye) 
  • Transcatheter selective intraophthalmic-artery chemotherapy, which involves delivering chemotherapy directly to the arteries behind the eye 
  • Conventional chemotherapy, sometimes delivered in combination with subconjunctival chemotherapy 
  • Radiation therapy that conforms to the tumor’s shape 
  • Radioactive plaque therapy, which involves delivering a high dose of radiation to the tumor with minimal or no damage to surrounding tissue

Saving the Affected Eye

Physicians in the Retinoblastoma Program use sophisticated tests to determine whether an eye affected by retinoblastoma is likely to function properly following treatment. If necessary, these tests can help physicians and families decide whether to remove the eye. Such tests include direct visual inspection of the eye and tumor under anesthesia, imaging evaluation (MRI), visual acuity assessments when feasible, and optic pathway function tests (visual evoked potential).

When the eye cannot be saved, our team offers ocular prosthetics. These sophisticated implants are designed in such a way that the artificial eye, artistically designed to match the other eye, can move in concert with the child’s healthy eye, allowing for a natural appearance.