Dr Arnold Strauss is the director of the Research Foundation. This photo was taken for the 2012 Research Annual Report

Arnold W. Strauss, MD


  • Emeritus, UC Department of Pediatrics
My colleagues and I are seeking to define gene mutations that cause pediatric heart disease so that we can better treat or prevent these conditions.
Arnold W. Strauss, MD

About

Biography

As a general pediatric cardiologist, I see outpatients for congenital heart disease, cardiomyopathy, genetic disorders and other issues. In my practice, I talk to patients directly and take time to answer all questions from patients and their families.

I was inspired to pursue my career by David Goldring, MD, who was the director of pediatric cardiology at St. Louis Children’s Hospital for many years.

In addition to helping patients and their families, I’m involved in research. My colleagues and I are seeking to define gene mutations that cause pediatric heart disease so that we can better treat or prevent these conditions.

I was honored to receive the 2006 American Heart Association’s Basic Science Research Award for work that led to finding genetic defects that can cause heart failure and sudden death in infants and children. I also received the 1991 E. Mead Johnson Award for Excellence in Pediatric Research and was elected to the National Academy of Medicine.

In my spare time, I love watching baseball and going to the beach.

MD: Washington University, St. Louis, MO, 1970.

Residency: Pediatrics, Children's Hospital, St. Louis, MO, 1970-72.

Fellowship: Cardiology, Children's Hospital and Washington University, St. Louis, MO, 1972-75.

Postdoctoral Fellowship: Merck, Sharp and Dohme Research Laboratories, Rahway, NJ, 1975-77.

Interests

Pediatric cardiology; genetic basis of pediatric heart disease; General Cardiology Outpatient Clinic

Services and Specialties

Research Areas

Additional Languages

French

Publications

The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system. Mandl, KD; Glauser, T; Krantz, ID; Avillach, P; Bartels, A; Beggs, AH; Biswas, S; Bourgeois, FT; Corsmo, J; Dauber, A; White, PS; Marsh, E; Grimberg, A; Hawkes, C. Genetics in Medicine. 2020; 22(2):371-380.

Elucidating the Beneficial Role of PPAR Agonists in Cardiac Diseases. Khuchua, Z; Glukhov, AI; Strauss, AW; Javadov, S. International Journal of Molecular Sciences. 2018; 19(11).

The Effects of PPAR Stimulation on Cardiac Metabolic Pathways in Barth Syndrome Mice. Schafer, C; Moore, V; Dasgupta, N; Javadov, S; James, JF; Glukhov, AI; Strauss, AW; Khuchua, Z. Frontiers in Pharmacology. 2018; 9:318.

The PPAR pan-agonist bezafibrate ameliorates cardiomyopathy in a mouse model of Barth syndrome. Huang, Y; Powers, C; Moore, V; Schafer, C; Ren, M; Phoon, CKL; James, JF; Glukhov, AV; Javadov, S; Vaz, FM; Jefferies, JL; Strauss, AW; Khuchua, Z. Orphanet Journal of Rare Diseases. 2017; 12(1):49.

Evaluation of Fellows' CrossTalk Effectiveness in Promoting Transdisciplinary Networking and Research. Wikenheiser-Brokamp, KA; Klein, M; Hershey, GKK; Devarajan, P; Dewitt, TG; Loch, J; Strauss, AW; Muglia, LJ; Hostetter, MK. Journal of Pediatrics. 2017; 181:5-6.e3.

Health-Related Quality of Life and Functional Status Are Associated with Cardiac Status and Clinical Outcome in Children with Cardiomyopathy. Sleeper, LA; Towbin, JA; Colan, SD; Hsu, D; Orav, EJ; Lemler, MS; Clunie, S; Messere, J; Fountain, D; Miller, TL; Wilkinson, JD; Lipshultz, SE. Journal of Pediatrics. 2016; 170:173-80.e1-4.

Mitochondrial trifunctional protein deficiency in human cultured fibroblasts: effects of bezafibrate. Djouadi, F; Habarou, F; Le Bachelier, C; Ferdinandusse, S; Schlemmer, D; Benoist, JF; Boutron, A; Andresen, BS; Visser, G; De Lonlay, P; Yamaguchi, S; Strauss, AW; Wanders, RJA; Bastin, J. Journal of Inherited Metabolic Disease. 2016; 39(1):47-58.

Enhancing Pediatric Fellows' Research Training: Development of an Office of Pediatric Clinical Fellowships. Klein, M; Hershey, GKK; Devarajan, P; Muglia, LJ; Wikenheiser-Brokamp, KA; Loch, J; Hostetter, MK; Strauss, AW; Dewitt, TG. Journal of Pediatrics. 2015; 167(3):506-7.e1.

Cardiac metabolic pathways affected in the mouse model of barth syndrome. Huang, Y; Powers, C; Madala, SK; Greis, KD; Haffey, WD; Towbin, JA; Purevjav, E; Javadov, S; Strauss, AW; Khuchua, Z. PLoS ONE. 2015; 10(6):e0128561.

Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance. Xiong, D; He, H; James, J; Tokunaga, C; Powers, C; Huang, Y; Osinska, H; Towbin, JA; Purevjav, E; Balschi, JA; Javadov, S; Mcgowan, FX; Strauss, AW; Khuchua, Z. American Journal of Physiology. Heart and Circulatory Physiology. 2014; 306(3):H326-H338.

Patient Ratings and Comments

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