John J. Brewington, MD

Member, Division of Pulmonary Medicine

Academic Affiliations

Instructor, UC Department of Pediatrics

Phone 513-636-6771



Pulmonary medicine; cystic fibrosis; flexible bronchoscopy; congenital airway malformations


Cystic fibrosis; CFTR modulators; patient-derived model systems

As faculty in pediatric pulmonary medicine, John cares for patients with a wide variety of airway and lung diseases. He has a particular interest in the care of patients with cystic fibrosis and congenital airway abnormalities, as well as those with chronic respiratory failure. His primary research focus centers around maximizing the benefit of new "modulator" therapies for patients with cystic fibrosis at the individual level. To achieve this end, he has focused on drug-drug interactions, epithelial biology, and individualized, patient-derived model systems of CFTR function.

MD: Wake Forest University, Winston-Salem, NC, 2009.

Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Chief Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2013.

Fellowship: Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2016.

Certification: Pediatrics, 2012.

Brewington JJ, McPhail GL, Clancy JP. Lumacaftor alone and combined with ivacaftor: preclinical and clinical trial experience of F508del CFTR correction. Expert Rev Respir Med. 2016;10(1):5-17.

Brewington JJ, Clancy JP. Diagnostic Testing in Cystic Fibrosis. Clin Chest Med. 2016 Mar;37(1):31-46.

Siracusa CM, Brewington JJ, Brockbank JC, Guilbert TW. Update in Pediatric Lung Disease 2014. Am J Respir Crit Care Med. 2015 Oct 15;192(8):918-23.