I am a pediatric endocrinologist who specifically treats patients with growth disorders and patients with Turner syndrome. I believe in an honest, open and completely transparent dialogue with the patient and family.
During my fellowship training, which involved both patient care and research, I developed my passion for improving the diagnosis and treatment of growth disorders. My mentorship at the University of North Carolina at Chapel Hill with Dr. Judson Van Wyk and Dr. Louis Underwood, two of the “greats” in this field, convinced me that this was the area I would pursue.
I believe in a rational approach to the work-up and management of children with concerns regarding growth and physical development. I adhere to a cost-conscious approach and guide myself first by a detailed history and exam, rather than jumping to nondiscriminatory testing. I also follow a stepwise approach to solving the medical problem, knowing we may not always find a specific cause for the child’s growth problem. This is something parents should always keep in mind.
I am currently on the board of directors of the Pediatric Endocrine Society and the American Board of Pediatrics Endocrinology Subboard. My past research led to the Food and Drug Administration approval of a growth peptide to treat patients with growth hormone resistance (rhIGF-1), and I’m an international expert in the area of growth hormone resistance.
My current research seeks to find better diagnostic approaches to solving problems related to poor childhood growth. We are also evaluating newer methods for the treatment of growth disorders and how to treat novel growth disorders. In addition, I am involved in several research projects related to the comorbidities of Turner syndrome, for which we are serving the largest clinical cohort in the U.S.
I have published more than 100 peer-reviewed manuscripts, more than 100 abstracts and 17 textbook chapters. I’ve also given more than 90 invited presentations at national and international meetings.
In my free time, I love being in nature. I’m active in hiking, cycling, swimming, kayaking and golf. I also like to read nonfiction books related to philosophy and history.
MD: University of Ghent, Belgium.
Residency: Pediatric and Adolescent Medicine, Cleveland Clinic Foundation Children's Hospital, Cleveland, OH.
Fellowship: Pediatric Endocrinology, University of North Carolina, Chapel Hill, NC.
Certification: Pediatrics, 1992; recertified, 1999, 2007; Pediatric Endocrinology, 1995; recertified, 2003, 2013.
Consultant for growth disorders and Turner syndrome
Growth disorders and Turner syndrome
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Abnormal Uterine Bleeding during Pubertal Induction with Transdermal Estrogen in Individuals with Turner Syndrome. Journal of Pediatric and Adolescent Gynecology. 2023; 36:358-362.
Growth Hormone Deficiency Following Traumatic Brain Injury in Pediatric and Adolescent Patients: Presentation, Treatment, and Challenges of Transitioning from Pediatric to Adult Services. Journal of Neurotrauma. 2023; 40:1274-1285.
Factors Associated With Response to Growth Hormone in Pediatric Growth Disorders: Results of a 5-year Registry Analysis. Journal of the Endocrine Society. 2023; 7:bvad026.
Early Growth Hormone Initiation Leads to Favorable Long-Term Growth Outcomes in Children Born Small for Gestational Age. Journal of Clinical Endocrinology and Metabolism. 2023; 108:1043-1052.
Using change in predicted adult height during GnRH agonist treatment for individualized treatment decisions in girls with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism. 2023; 36:299-308.
Successful Treatment of Hypoglycemia With Alpelisib in Pediatric Patients With PIK3CA -Related Overgrowth Spectrum. 2023; 1.
Somapacitan in children born small for gestational age: a multi-centre, open-label, controlled phase 2 study. European Journal of Endocrinology. 2023; 188:lvac008.
LBMON197 Predictors Of Response To Growth Hormone Treatment In Pediatric Growth Disorders: Analysis From The Answer Program And Nordinet® IOS. Journal of the Endocrine Society. 2022; 6:a592.
OR18-6 Tracking the Diagnosis and Progression of Madelung Deformity in Pediatric Turner Syndrome Patients. Journal of the Endocrine Society. 2022; 6:a619.
RF26 | PMON335 Once-Weekly Somapacitan Versus Daily Growth Hormone in Children Born Small for Gestational Age: Results From a Randomized Phase 2 Trial. Journal of the Endocrine Society. 2022; 6:a646.