A photo of Vidya Chidambaran.

Director, Perioperative Pain Management

Associate Professor, UC Department of Pediatrics

513-636-8021

My Biography & Research

Biography

Dr. Chidambaran has been a recipient of the Young Investigator Award – 1st place for 2 consecutive years (2010, 2011) from the Society of Pediatric Anesthesia, Outstanding and Best Abstract awards in 2016 and 2017 respectively from the Society of Pediatric Pain Medicine for her research. Her mentees have similarly received research awards over the last few years. She has given international talks and organized symposia at national and international pain meetings including the American Pain Society and International Association for the Study of Pain. She is the program chair for the annual meeting of the Society of Pediatric Pain Medicine in 2019, and the co-chair of the Pain and Genetics SIG at the American Pain Society. She is also a member of institutional research committees (Clinical, Translational, Outcomes, and Health Services (CTOHS) and the Integrated Research Advisory Committee (IRAC)) at Cincinnati Children's Hospital Medical Center.

She recently assumed the role of the director of Perioperative Pain Service (2017). Her research in perioperative pain, chronic postsurgical pain, opioid safety, pharmacogenomics and epigenetics has been supported by the Cincinnati Children's Hospital Center for Clinical and Translational Science and Training (CCTST), through start-up funds (Clinical Research Feasibility Funds (2010-2011) and T1 Junior Faculty Award (2011-2012)), followed by extramural funding: APSF / ASA Safety Scientist Career Development Award (2012-2014) from the Anesthesia Patient Safety Foundation, and the Translational Scholar Career Awards in Pharmacogenomics and Personalized Medicine (K23) from Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2014-2019). Recent grants from Center for Pediatric Genomics (2016-2017) and Shared Facility Discovery Award from Cincinnati Children's Hospital Medical Center research Fund (2016-2017) supported “A genetic-epigenetic approach to predict chronic post-surgical pain in children.” She has received several research awards (see CV), is the PI for multisite studies, and produced >40 peer-reviewed publications. Dr. Chidambaran is co-inventor and holds two patent applications.

Additional Languages

Hindi, Tamil

Clinical Interests

Pediatric anesthesia; perioperative pain; ultrasound guided regional anesthesia

Research Interests

Pharmacogenomics; PK-PD modeling; genomics/epigenetics pain research; psychosocial factors; outcomes research

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Departments

Anesthesia, Anesthesia, Cincinnati Center for Eosinophilic Disorders Research

My Education

MBBS: Medicine, Bangalore Medical College, India, 1997.

MD: Anesthesiology, Kasturba Medical College, India, 2000.

Senior Resident: Amrita Institute of Medical Sciences, Kochi, Kerala, India, 2001-2002.

Internship: Anesthesiology, Jackson Memorial Hospital, Miami, Florida, 2003-2004.

Residency: Anesthesiology, Brookdale University Hospital, Brooklyn, New York, 2004-2007.

Fellowship: Pediatric Anesthesia, Johns Hopkins Hospital, Baltimore, Maryland, 2007-2008.

Certificate: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH, 2015.

Masters’ Degree: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH, 2017.

My Publications

Chidambaran V, Subramanyam R, Ding L, Sadhasivam S, Geisler K, Stubbeman B, Sturm P, Jain V, Eckman MH. Cost-effectiveness of intravenous acetaminophen and ketorolac in adolescents undergoing idiopathic scoliosis surgery. Pediatr Anesth. 2018;00:1–12.

Chidambaran V, McAuliffe JJ. Opioid-induced respiratory depression: the role of genetics. Expert Review of Precision Medicine and Drug Development. 2017.

Chidambaran V, Zhang X, Martin LJ, Ding L, Weirauch MT, Geisler K, Stubbeman BL, Sadhasivam S, Ji H. DNA methylation at the Mu Opioid Receptor gene (OPRM1) promoter predicts preoperative, acute and chronic post-surgical pain after spine fusion. Pharmgenomics Pers Med. 2017 May 9;10:157-168.

Chidambaran V, Ding L, Moore D, Spruance K, Cudilo EM, Pilipenko V, Hossain M, Sturm P, Kashikar-Zuck S, Martin LJ, Sadhasivam S. Predicting the Pain Continuum after Adolescent Idiopathic Scoliosis Surgery- A Prospective Cohort Study. Eur J Pain. 2017 Mar 27.

Chidambaran V, Pilipenko V, Spruance K, Venkatasubramanian R, Niu J, Fukuda T, Mizuno T, Zhang K, Kaufman K, Vinks AA, Martin LJ, Sadhasivam S. FAAH - Morphine Interaction Influences Ventilatory Response to Hypercapnia and Postoperative Opioid Outcomes in Children. Pharmacogenomics. 2017 Jan;18(2):143-156.

Chidambaran V, Sadhasivam S, Mohamed M. Codeine and Opioid Metabolism - Implications and alternatives for pediatric pain management. Anesthesiology. 2016.

Chidambaran V, Venkatasubramanian R, Zhang X, Martin LJ, Niu J, Mizuno T, Fukuda T, Meller J, Vinks AA, Sadhasivam S. ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children. Pharmacogenomics J. 2016 Jan 26.

Chidambaran V, Costandi A, D’Mello AJ. Propofol: A Review of its Role in Pediatric Anesthesia and Sedation. CNS Drugs. 2015 Aug 20.

Chidambaran V, Venkatasubramanian R, Sadhasivam S, Esslinger H, Cox S, Diepstraten J, Fukuda T, Inge T, Knibbe CAJ, Vinks AA. Population Pharmacokinetic-Pharmacodynamic Modeling And Dosing Simulation Of Propofol Maintenance Anesthesia In Severely Obese Adolescents. Paediatr Anaesth. 2015 May 13.

Chidambaran V, Mavi J, Esslinger H, Pilipenko V, Martin LJ, Zhang K, Sadhasivam S. Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents. Pharmacogenomics J. 2015 Jun;15(3):255-62.