My life experiences with family members needing medical care during their illnesses, and the nobility of a profession where you can make a difference in others' lives, drew me to becoming a physician.
Pediatrics was always my passion. I relate well to children and I enjoy taking care of them. My clinical specialties are pediatric anesthesia, perioperative pain and ultrasound-guided regional analgesia. In addition, anesthesia is a field that adds lifesaving skills and allows me to care for patients in times of high stress, such as when undergoing surgery. I use my skills to help manage pain, which can enable their recovery.
My research areas include personalized medicine, pharmacogenomics, epigenetics, chronic post-surgical pain and psychosocial predictors of pain. My clinical field and experience led me to believe each individual is unique. In addition, it showed me the importance of the big picture in improving perioperative outcomes, which includes understanding gene-environmental interactions. This led to my desire to combine my clinical skills with my research interests.
The goals of my research are: 1) to identify preoperative interventions for the optimization of pain management; 2) to develop genomic and epigenetic risk predictors for perioperative and chronic post-surgical pain response; and 3) to develop pharmacologic targets based on genomic studies.
I am honored to have received many awards and appointments throughout my career, including:
My mentees have similarly received research awards over the last few years. I’ve given international talks and organized symposia at national and international pain meetings, including those of the American Pain Society and the International Association for the Study of Pain.
MBBS: Medicine, Bangalore Medical College, India, 1997.
MD: Anesthesiology, Kasturba Medical College, India, 2000.
Senior Resident: Amrita Institute of Medical Sciences, Kochi, Kerala, India, 2001-2002.
Internship: Anesthesiology, Jackson Memorial Hospital, Miami, Florida, 2003-2004.
Residency: Anesthesiology, Brookdale University Hospital, Brooklyn, New York, 2004-2007.
Fellowship: Pediatric Anesthesia, Johns Hopkins Hospital, Baltimore, Maryland, 2007-2008.
Certificate: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH, 2015.
Masters’ Degree: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH, 2017.
Pediatric anesthesia; perioperative pain; ultrasound guided regional anesthesia
Anesthesia, Perioperative Pain Management
Pharmacogenomics; PK-PD modeling; genomics/epigenetics pain research; psychosocial factors; outcomes research
Anesthesia, Clinical Pharmacology
Multicenter study of OPRM1 A118G and promoter-region DNA methylation associations with opioid outcomes and chronic postsurgical pain after pediatric musculoskeletal surgery. Pain Reports. 2024; 9:e1201.
The role of cytokines in acute and chronic postsurgical pain after major musculoskeletal surgeries in a quaternary pediatric center. Brain, Behavior, and Immunity. 2024; 122:596-603.
A survey of practice in the anesthetic management of adolescent idiopathic scoliosis spine fusion by the North American Pediatric Spine Anesthesiologists Collaborative. Pediatric Anesthesia. 2024; 34:645-653.
Error traps and preventative strategies for adolescent idiopathic scoliosis spinal surgery. Pediatric Anesthesia. 2023; 33:894-904.
Association of race and socioeconomic status with time to pain control among pediatric trauma patients managed nonoperatively. The Journal of Trauma and Acute Care Surgery. 2023; 95:403-410.
Current Evidence for Biological Biomarkers and Mechanisms Underlying Acute to Chronic Pain Transition across the Pediatric Age Spectrum. Journal of Clinical Medicine. 2023; 12:5176.
Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center. American Journal of Health-System Pharmacy. 2023; 80:852-859.
Family-Centered Qualitative Study For An Empathic Understanding Of Acute Pain Experience In Pediatric Non Hispanic White And Non Hispanic Black Cohorts. Journal of Pain. 2023; 24:85-86.
Quantitative Comparison Of Parental-Child Factors Influencing Acute Pain Experience Of Non-Hispanic Black And White Children. Journal of Pain. 2023; 24:88.
Retrospective study comparing outcomes of multimodal epidural and erector spinae catheter pain protocols after pectus surgery. Journal of Pediatric Surgery. 2023; 58:397-404.
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