A photo of Robert W. Frenck Jr.

Medical Director, Division of Infectious Diseases

Director, Vaccine Research Center

Professor, UC Department of Pediatrics

513-636-7839

513-636-3959

Board Certified

Best Doctors logo

My Biography & Research

Biography

Robert W. Frenck Jr., MD, received his undergraduate degree from the University of California at San Diego in 1977 followed by his doctor of medicine degree from the University of Texas Health Science Center at Houston in 1981. He trained at the National Naval Medical Center in Bethesda, Maryland, completing his pediatric residency in 1984. After three years as a general pediatrician at the US Naval Hospital, Japan, he entered pediatric infectious disease fellowship training at the University of Texas Health Science Center at Houston, which he completed in 1990. Dr. Frenck is board-certified in both pediatrics and infectious diseases.

Dr. Frenck's research interests include therapeutic and vaccine clinical trials with special interest in enteric diseases. After completing a 25-year career in the Navy, Dr. Frenck joined the UCLA Center for Vaccine Research in 2004 and served until 2006 as director of the center and a professor of pediatrics at UCLA School of Medicine. Dr. Frenck has been active in the American Academy of Pediatrics and currently serves on the Red Book Committee. He is an acknowledged authority in infectious diseases and has authored over 60 articles and book chapters on various aspects of this subject.

Clinical Interests

Vaccine research; enteric diseases; travel medicine

Research Interests

Enteric diseases; vaccinology

Academic Affiliation

Professor, UC Department of Pediatrics

Divisions

Infectious Diseases, Infectious Diseases

Cincinnati Children's Blog

Top 6 Reasons Why Clinical Trials Are Important

BlogResearch and Discoveries

Top 6 Reasons Why Clinical Trials Are Important

By Dr. Robert Frenck11/27/2018

Reminder

BlogVaccines

Reminder: Incoming 7th & 12th Graders Need Meningococcal Vaccine

By Dr. Robert Frenck7/28/2016

Vaccines

BlogVaccines

Vaccines: Their Own Worst Enemy

By Dr. Robert Frenck9/5/2013

My Locations

My Education

BA: University of California at San Diego, San Diego, CA, 1977.

MD: University of Texas Medical School at Houston, Houston, TX, 1981.

Internship and Residency: US Naval Hospital, Bethesda, MD, 1981-1984.

Fellowship: Pediatric Infectious Diseases, University of Texas Medical School at Houston, Houston, TX, 1987-1990.

My Publications

Persistence of immune responses through 36 months in healthy adults after vaccination with a novel Staphylococcus aureus 4-Antigen Vaccine (SA4Ag). Creech, CB; Frenck, RW; Fiquet, A; Feldman, R; Kankam, MK; Pathirana, S; Baber, J; Radley, D; Cooper, D; Eiden, J; et al. Open Forum Infectious Diseases. 2020; 7.

Consensus Report on Shigella Controlled Human Infection Model: Clinical Endpoints. MacLennan, CA; Riddle, MS; Chen, WH; Talaat, KR; Jain, V; Louis Bourgeois, A; Frenck, R; Kotloff, K; Porter, CK. Clinical Infectious Diseases. 2019; 69:S591-S595.

Consensus Report on Shigella Controlled Human Infection Model: Conduct of Studies. Talaat, KR; Louis Bourgeois, A; Frenck, RW; Chen, WH; MacLennan, CA; Riddle, MS; Suvarnapunya, AE; Brubaker, JL; Kotloff, KL; Porter, CK. Clinical Infectious Diseases. 2019; 69:S580-S590.

Safety and immunogenicity of a vaccine for extra-intestinal pathogenic Escherichia coli (ESTELLA): a phase 2 randomised controlled trial. Jr, FR W; Ervin, J; Chu, L; Abbanat, D; Spiessens, B; Go, O; Haazen, W; van den Dobbelsteen, G; Poolman, J; Thoelen, S; et al. Lancet Infectious Diseases. 2019; 19:631-640.

A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against Shigella sonnei. Jr, FR W; Baqar, S; Alexander, W; Dickey, M; McNeal, M; El-Khorazaty, J; Baughman, H; Hoeper, A; Barnoy, S; Suvarnapunya, AE; et al. Vaccine. 2018; 36:4880-4889.

Cat-Scratch Disease, a Diagnostic Consideration for Chronic Recurrent Multifocal Osteomyelitis. Harry, O; Schulert, GS; Frenck, RW; Shapiro, AH; Woltmann, JL; Smith, JA; Grom, AA. Journal of Clinical Rheumatology: practical reports on rheumatic and musculoskeletal disease. 2018; 24:287-290.

Cat-Scratch Disease, a Diagnostic Consideration for Chronic Recurrent Multifocal Osteomyelitis. Harry, O; Schulert, GS; Jr, FR W; Shapiro, AH; Woltmann, JL; Smith, JA; Grom, AA. Journal of Clinical Rheumatology: practical reports on rheumatic and musculoskeletal disease. 2018; 24:287-290.

Giardia intestinalis (Giardiasis). Washam, M; Frenck, RW. Principles and Practice of Pediatric Infectious Diseases. : Elsevier; Elsevier; 2018.

Developing and utilizing controlled human models of infection. Porter, CK; Bourgeois, AL; Frenck, RW; Prouty, M; Maier, N; Riddle, MS. Vaccine. 2017; 35:6813-6818.

Lot-to-lot consistency, safety and immunogenicity of 3 lots of Haemophilus influenzae type b conjugate vaccine: results from a phase III randomized, multicenter study in infants. Klein, NP; Abu-Elyazeed, R; Cornish, M; Leonardi, ML; Weiner, LB; Silas, PE; Grogg, SE; Varman, M; Frenck, RW; Cheuvart, B; et al. Vaccine. 2017; 35:3564-3574.