Iris Gutmark-Little, MD
- Member, Division of Endocrinology
- Director, Turner Syndrome Center
- Director, Growth Center
- Associate Professor, UC Department of Pediatrics
- iris.little@cchmc.org
- Board Certified
About
Biography
As a pediatric endocrinologist, I focus my care on children and adolescents with thyroid disease, growth problems and disorders of puberty. I also treat girls with Turner syndrome, and I practice general pediatric endocrinology as well.
Children are funny, smart and resilient, and I always knew I wanted to work with them. I love interacting with their families. Pediatric endocrinology lets me see many different types of patients, and since there are treatments for many of the diseases we treat, I see children return to health.
I practice patient-centered care and education. I put myself in the shoes of the family and child and listen carefully to everything they say. I work very hard to make sure the family and patient understand my thought process for the treatment plan I am recommending.
I’ve been taking care of girls with Turner syndrome for more than 10 years. In collaboration with families, I focus on the specific things that affect their child’s life the most, while making sure we cover all of the screening and treatment needs. In my research, we are trying to learn why patients with Turner syndrome are at risk for cardiovascular disease.
In my free time, I have three wonderful children who keep me busy and happy. I love to exercise, specifically weight-lifting. I also enjoy good food and drink — especially coffee!
BS: Louisiana State University, Baton Rouge, LA, 2000
MD: Johns Hopkins University School of Medicine, Baltimore, MD, 2004
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2007
Fellowship: Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2010
Certifications: General Pediatrics, American Board of Pediatrics, 2008; Pediatric Endocrinology, American Board of Pediatrics, pending 2011
Interests
Turner syndrome; general pediatric endocrinology; growth; puberty; hypopituitarism
Services and Specialties
Interests
Cardiovascular disease in Turner syndrome; long-acting growth hormone
Research Areas
Additional Languages
German, HebrewLocations (2)
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
Madelung Deformity: A Current Concepts Review. Journal of Hand Surgery-American Volume. 2026; 51(8):903-913.
Examining Racial and Ethnic Differences in Referral and Management of Central Precocious Puberty in a Pediatric Endocrinology Clinic. Journal of Pediatrics. 2026; 295:115116.
From X to Y and everything in between: navigating care for patients with 45,X/46,XY mosaicism. Endocrine Abstracts. 2026.
Adipose tissue distribution and metabolic profile of young individuals with turner syndrome. Journal of the Endocrine Society. 2026; 10(4):bvag016.
Management of Arginine Vasopressin Deficiency (Central Diabetes Insipidus) in Neonates and Infants. Hormone Research in Paediatrics. 2025; 1-11.
Laboratory patterns differ between patients with severe vs milder forms of congenital hypothyroidism. Endocrine Abstracts. 2025.
Clinical outcomes of switching to lonapegsomatropin from somatropin for treatment of pediatric growth hormone deficiency. Journal of Pediatric Endocrinology and Metabolism. 2025; 38(3):248-253.
Transition to Adult Care in Turner Syndrome: Research Gaps and Strategies for Achieving Success. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 2025; 199(1):e32131.
A145 EFFECT OF DUPILUMAB ON WEIGHT IN PATIENTS AGED 1 TO 11 YEARS WITH ACTIVE EOSINOPHILIC ESOPHAGITIS (EOE): RESULTS FROM THE PHASE 3 EOE KIDS STUDY. Journal of the Canadian Association of Gastroenterology. 2025; 8(Supplement_1):i59-i60.
Prevalence, diagnostic features, and medical outcomes of females with Turner syndrome with a trisomy X cell line (45,X/47,XXX): Results from the InsighTS Registry. American Journal of Medical Genetics, Part A. 2024; 194(12):e63819.
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