A photo of Russel Hirsch.

Director, Pulmonary Hypertension Service

Professor, UC Department of Pediatrics


Board Certified

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About Me

Clinical Interests

Percutaneous interventions for the palliation or treatment of congenital heart disease; treatment of all forms of pediatric pulmonary hypertension; interventional catheterization; pulmonary hypertension; General Cardiology Outpatient Clinic

Research Interests

Device closure of congenital heart defects; feasibility of covered stent use in coarctation of the aorta; pulmonary vascular complications associated with congenital diaphragmatic hernia and chronic lung disease; cardiac manifestations of post bone-marrow transplant thrombotic microangiopathy; non-invasive evaluation of pulmonary hypertension in pediatric age patients; validation of new methods for assessing oxygen consumption in the cardiac catheterization laboratory

Academic Affiliation

Professor, UC Department of Pediatrics

Clinical Divisions

Heart, Hereditary Hemorrhagic Telangiectasia, Pulmonary Hypertension, Catheterization and Intervention, Bronchopulmonary Dysplasia BPD

My Education

MBChB: University of Cape Town, Cape Town, South Africa.

Residency: St. Louis Children's Hospital, St. Louis, MO.

Fellowship: St. Louis Children's Hospital and Washington University School of Medicine, St. Louis, MO.

Certification: Pediatrics, 1994, 2002 (renew); Pediatric Cardiology, 1998, 2005.

My Publications

Cardiovascular magnetic resonance imaging derived septal curvature in neonates with bronchopulmonary dysplasia associated pulmonary hypertension. Critser, PJ; Higano, NS; Lang, SM; Kingma, PS; Fleck, RJ; Hirsch, R; Taylor, MD; Woods, JC. Journal of Cardiovascular Magnetic Resonance. 2020; 22.

Pediatric pulmonary hypertension: insulin-like growth factor-binding protein 2 is a novel marker associated with disease severity and survival. Griffiths, M; Yang, J; Nies, M; Vaidya, D; Brandal, S; Williams, M; Matsui, EC; Grant, T; Damico, R; Ivy, D; et al. Pediatric Research. 2020; 88:850-856.

Residence at moderately high altitude and its relationship with WHO Group 1 pulmonary arterial hypertension symptom severity and clinical characteristics: the Pulmonary Hypertension Association Registry. Fakhri, S; Hannon, K; Moulden, K; Peterson, R; Hountras, P; Bull, T; Maloney, J; De Marco, T; Ivy, D; Thenappan, T; et al. Pulmonary Circulation. 2020; 10:2045894020964342-204589402096434.

Elevated Interleukin-6 Levels Predict Clinical Worsening in Pediatric Pulmonary Arterial Hypertension. Chen, JY; Griffiths, M; Yang, J; Nies, MK; Damico, RL; Simpson, CE; Vaidya, RD; Brandal, S; Ivy, DD; Austin, ED; et al. The Journal of Pediatrics. 2020; 223:164-169.e1.

Pharmacokinetics of Oral Treprostinil in Children with Pulmonary Arterial Hypertension. Hopper, RK; Ivy, DD; Yung, D; Mullen, MP; Hanna, BD; Kirkpatrick, E; Hirsch, R; Austin, ED; Fineman, J; Solum, D; et al. Journal of Cardiovascular Pharmacology. 2020; 76:94-100.

Pulmonary venous Doppler patterns and midterm outcomes in fetuses with left-sided obstructive lesions and restrictive atrial septum. Schneider, K; Hahn, E; Statile, C; Hirsch, R; Khoury, PR; Cnota, J; Divanovic, A. Prenatal Diagnosis. 2020; 40:776-784.

Size Does Not Matter: The Outdated Practice of Using Oversized Organs for Recipients with Elevated PVR. . Thangappan, K; Zafar, F; Hirsch, R; Chin, C; Lehenbauer, D; O'Donnell, A; Morales, DL. Journal of Heart and Lung Transplantation. 2020; 39:S221-S221.

Quantitative Coronary Angiography Can Predict Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Recipients. McGovern, E; Hirsch, R; Chin, P; Morales, DL; Chin, C. Journal of Heart and Lung Transplantation. 2020; 39:S454-S454.

Complement blockade for TA-TMA: Lessons learned from a large pediatric cohort treated with eculizumab. Jodele, S; Dandoy, CE; Lane, A; Laskin, BL; Laskin, B; Teusink-Cross, A; Myers, KC; Wallace, G; Nelson, AS; Nelson, A; et al. Blood. 2020; 26:S138-S138.

Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension. Zhu, N; Pauciulo, MW; Welch, CL; Lutz, KA; Coleman, AW; Gonzaga-Jauregui, C; Wang, J; Grimes, JM; Martin, LJ; He, H; et al. Genome Medicine: medicine in the post-genomic era. 2019; 11.