Daniel G. Leino, MD, MPH

A novel POT1-TPD presentation: A germline pathogenic POT1 variant discovered in a patient with newly diagnosed posterior fossa ependymoma. Gilene, S; Knapke, S; Leino, D; Roy, S; Raskin, S. Cancer genetics. 2025; 292-293:38-43.

Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice. Cantrell, R; Alex Feldman, H; Rosenfeldt, L; Ali, A; Gourley, B; Sprague, C; Leino, D; Crosby, J; Revenko, A; Monia, B; Waggoner, SN; Palumbo, JS. JCI insight. 2025; 10:e181063.

The human and non-human primate developmental GTEx projects. Coorens, TH H; Guillaumet-Adkins, A; Kovner, R; Linn, RL; Roberts, VH J; Sule, A; Van Hoose, PM; Zou, S; Ramos, E; Price, A; Salehi, A; Roberts, R; Rasool, I; Rossi, C. Nature. 2025; 637:557-564.

Factor XII promotes the thromboinflammatory response in a rat model of venoarterial extracorporeal membrane oxygenation. Kharnaf, M; Zafar, F; Hogue, S; Rosenfeldt, L; Cantrell, RL; Sharma, BK; Pearson, A; Sprague, C; Leino, D; Abplanalp, WA; Morales, D; Tweddell, J; Qualls, JE; Palumbo, JS. Journal of Thoracic and Cardiovascular Surgery. 2024; 168:e37-e53.

Use of Teduglutide in the Management of Gastrointestinal Graft-versus-Host Disease in Children and Young Adults. Ramos, KN; Leino, D; Luebbering, N; Grimley, MS; Badia, P; Davies, SM; Khandelwal, P. Transplantation and Cellular Therapy. 2024; 30:454.e1-454.e6.

Successful Use of Teduglutide As Adjunctive Therapy in the Management of GI GvHD in Children and Young Adults: A Single Center Case Series. Ramos, KN; Leino, D; Luebbering, N; Grimley, M; Badia, P; Davies, SM; Khandelwal, P. Transplantation and Cellular Therapy. 2024; 30:s136.

Transcriptome analysis in acute gastrointestinal graft-versus host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease. Khandelwal, P; Lounder, DT; Bartlett, A; Haberman, Y; Jegga, AG; Ghandikota, S; Koo, J; Luebbering, N; Leino, D; Abdullah, S; Karns, R; Nelson, AS; Denson, LA; Davies, SM. Haematologica: the hematology journal. 2023; 108:1803-1816.

T-cell infiltrate intensity is associated with delayed response to treatment in late acute cellular rejection in pediatric liver transplant recipients. Peters, AL; Rogers, M; Begum, G; Sun, Q; Fei, L; Leino, D; Hildeman, D; Woodle, ES. Pediatric Transplantation. 2023; 27:e14475.

Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation. Tweddell, JS; Kharnaf, M; Zafar, F; Riggs, KW; Reagor, JA; Monia, BP; Revenko, A; Leino, DG; Owens, AP; Martin, JK; Gourley, B; Rosenfeldt, L; Palumbo, JS. Blood Advances. 2023; 7:1404-1417.

A Murine Model of Veno-Arterial Extracorporeal Membrane Oxygenation. Kharnaf, M; Hogue, S; Wilkes, Z; Reagor, JA; Leino, DG; Gourley, B; Rosenfeldt, L; Ma, Q; Devarajan, P; Palumbo, JS; Tweddell, JS; Zafar, F. ASAIO Journal. 2022; 68:e243-e250.