The Cancer and Blood Diseases Institute at Cincinnati Children’s provides expert care for children with newly diagnosed and relapsed neuroblastoma. Our Neuroblastoma Advanced Therapies Center offers patients and families the full spectrum of medical, surgical and diagnostic care, as well as supportive services.

The director of the Neuroblastoma Advanced Therapies Center is Brian Weiss, MD. Dr. Weiss is a national leader in the study of improved treatments for neuroblastoma. His research focuses on new approaches to targeting and killing neuroblastoma cells. Dr. Weiss leads national studies on neuroblastoma therapies and is a leader in the COG neuroblastoma committee and the New Approaches to Neuroblastoma Therapy (NANT) consortium.

Advancing Targeted Radiation Therapies

Cincinnati Children’s is a leading center for the development and clinical testing of new approaches to neuroblastoma treatment. Our physicians and researchers are involved in many national and international research studies and develop their own protocols when treating neuroblastoma in children and infants. This work provides our patients with early access to new anticancer therapies, sometimes years before they become widely available. Such therapies include 131I-MIBG therapy, which targets radiation directly to neuroblastoma cells while sparing healthy tissue. Cincinnati Children’s is one of just a few pediatric centers in the country providing the technically demanding 131I-MIBG therapy, which requires special facilities for radiation safety and a collaborative approach to care across multiple divisions.

We also specialize in blood and marrow transplantation. In fact, our transplant team has performed more than 1,300 blood and marrow transplants, including more than 160 for advanced neuroblastoma. The pediatric Bone Marrow Transplantation Program at Cincinnati Children’s is one of the largest in the country.

At many medical centers, patients and families must travel to different floors or even different buildings to see various specialists. Our multidisciplinary clinic within the Cancer and Blood Diseases Institute brings these specialists together, making visits more convenient and enabling the highest level of communication and coordination of care. Leading the team are oncologists and blood and marrow transplant specialists, who have extensive experience in caring for pediatric neuroblastoma patients and in conducting clinical research. Other members of the team include physicians specializing in:

New patients undergo a comprehensive evaluation in our clinic. Our team then develops a detailed assessment and treatment recommendations. We provide referring physicians with regular updates to ensure coordinated care.

Depending on the child’s needs, the team may include other Cincinnati Children’s specialists, including experts in:

Nursing Excellence

Nurses play an integral role on the multidisciplinary team, providing patient care and extensive education. In fact, Cincinnati Children’s is known for nursing excellence. In 2009, the medical center received Magnet status from the Commission on the Magnet Recognition Program. This is the gold standard for recognizing nursing excellence and collaboration among all care providers and patients. Of approximately 5,700 hospitals in the United States, only 6 percent have achieved this status from the Magnet Recognition Program.