A photo of Qing Richard Lu.

Beatrice C. Lampkin Endowed Chair in Cancer Epigenetics

Scientific Director, Brain Tumor Center

Professor, UC Department of Pediatrics

513-636-7684

513-636-3549

Biography & Affiliation

Academic Affiliation

Professor, UC Department of Pediatrics

Departments

Experimental Hematology and Cancer Biology, Cancer and Blood Diseases, Developmental Biology

Education

BS: Peking Normal University, Beijing, China, 1988.

MS: Rutgers University, Piscataway, NJ, 1993.

PhD: Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 1997.

Postdoctoral Fellow: Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, 1997-2002.

Publications

Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. Zhang, L; He, X; Liu, X; Zhang, F; Huang, LF; Potter, AS; Xu, L; Zhou, W; Zheng, T; Luo, Z; et al. Cancer Cell. 2019; 36:302-318.e7.

HDAC3 Deficiency Promotes Liver Cancer through a Defect in H3K9ac/H3K9me3 Transition. Ji, H; Zhou, Y; Zhuang, X; Zhu, Y; Wu, Z; Lu, Y; Li, S; Zeng, Y; Lu, QR; Huo, Y; et al. Cancer Research. 2019; 79:3676-3688.

Developmental origins and oncogenic pathways in malignant brain tumors. Lu, QR; Qian, L; Zhou, X. Wiley Interdisciplinary Reviews: Developmental Biology. 2019; 8.

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Weng, Q; Wang, J; Wang, J; He, D; Cheng, Z; Zhang, F; Verma, R; Xu, L; Dong, X; Liao, Y; et al. Cell Stem Cell. 2019; 24:707-723.e8.

RUNX represses Pmp22 to drive neurofibromagenesis. Hall, A; Choi, K; Liu, W; Rose, J; Zhao, C; Yu, Y; Na, Y; Cai, Y; Coover, RA; Lin, Y; et al. Science Advances. 2019; 5.

A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism. Ou, Z; Ma, Y; Sun, Y; Zheng, G; Wang, S; Xing, R; Chen, X; Han, Y; Wang, J; Lu, QR; et al. Cell Reports. 2019; 26:2984-2997.e4.

Clinical and genetic spectrum of a large cohort of children with epilepsy in China. Yang, L; Kong, Y; Dong, X; Hu, L; Lin, Y; Chen, X; Ni, Q; Lu, Y; Wu, B; Wang, H; et al. Genetics in Medicine. 2019; 21:564-571.

Therapeutic targets for malignant peripheral nerve sheath tumors. Wu, LM N; Lu, QR. Future Neurology. 2019; 14.

The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner. Jiang, M; Rao, R; Wang, J; Wang, J; Xu, L; Wu, LM; Chan, JR; Wang, H; Lu, QR. Glia. 2018; 66:1947-1959.

Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8. Marie, C; Clavairoly, A; Frah, M; Hmidan, H; Yan, J; Zhao, C; Van Steenwinckel, J; Daveau, R; Zalc, B; Hassan, B; et al. Proceedings of the National Academy of Sciences of USA. 2018; 115:EB246-EB255.