A photo of Qing Richard Lu.

Beatrice C. Lampkin Endowed Chair in Cancer Epigenetics

Scientific Director, Brain Tumor Center

Professor, UC Department of Pediatrics

513-636-7684

513-636-3549

Biography & Affiliation

Clinical Interests

Neuro-oncology

Academic Affiliation

Professor, UC Department of Pediatrics

Research Divisions

Experimental Hematology and Cancer Biology, Cancer and Blood Diseases, Developmental Biology



Blog Posts

Cracking the Genetic Code of Malignant Peripheral Nerve Sheath Tumors

Genomics and Development

Cracking the Genetic Code of Malignant Peripheral Nerve Sheath Tumors

Qing Richard Lu, PhD7/3/2019

Shutting Down Glioblastoma at Its Earliest Moments

Cancer

Shutting Down Glioblastoma at Its Earliest Moments

Qing Richard Lu, PhD7/3/2019

How CHD8 Mutations Contribute to Autism Spectrum Disorders

Mind Brain Behavior

How CHD8 Mutations Contribute to Autism Spectrum Disorders

Qing Richard Lu, PhD6/30/2019

Education

BS: Peking Normal University, Beijing, China, 1988.

MS: Rutgers University, Piscataway, NJ, 1993.

PhD: Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 1997.

Postdoctoral Fellow: Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, 1997-2002.

Publications

Selected Publication

CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair. Wang, J; Wang, J; Yang, L; Zhao, C; Wu, LN; Xu, L; Zhang, F; Weng, Q; Wegner, M; Lu, QR. Nature Communications. 2020; 11.

Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction after Spinal Cord Injury. Ueno, M; Nakamura, Y; Nakagawa, H; Niehaus, JK; Maezawa, M; Gu, Z; Kumanogoh, A; Takebayashi, H; Lu, QR; Takada, M; et al. Cerebral Cortex. 2020; 30:5702-5716.

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Althoff, MJ; Nayak, RC; Hegde, S; Wellendorf, AM; Bohan, B; Filippi, MD; Xin, M; Richard Lu, Q; Geiger, H; Zheng, Y; et al. Blood. 2020; 136:1824-1836.

Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes. Wang, J; Lu, QR. Neurobiology of Disease. 2020; 144:105040-105040.

EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways. Wang, J; Yang, L; Dong, C; Wang, J; Xu, L; Qiu, Y; Weng, Q; Zhao, C; Xin, M; Lu, QR. Science Advances. 2020; 6:eaaz6477-eaaz6477.

Chromatin remodelers in oligodendroglia. Parras, C; Marie, C; Zhao, C; Lu, QR. Glia. 2020; 68:1604-1618.

Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. Zhang, L; He, X; Liu, X; Zhang, F; Huang, LF; Potter, AS; Xu, L; Zhou, W; Zheng, T; Luo, Z; et al. Cancer Cell. 2019; 36:302-318.e7.

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Weng, Q; Wang, J; Wang, J; He, D; Cheng, Z; Zhang, F; Verma, R; Xu, L; Dong, X; Liao, Y; et al. Cell Stem Cell. 2019; 24:707-723.e8.

A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration. He, X; Zhang, L; Queme, LF; Liu, X; Lu, A; Waclaw, RR; Dong, X; Zhou, W; Kidd, G; Yoon, S; et al. Nature Medicine. 2018; 24:338-351.

Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Wu, LM N; Deng, Y; Wang, J; Zhao, C; Wang, J; Rao, R; Xu, L; Zhou, W; Choi, K; Rizvi, TA; et al. Cancer Cell. 2018; 33:292-308.e7.