I’ve always been fascinated by the immune system and also felt a calling to pediatrics. I enjoy working with people and developing long-term relationships with patients and families, so my career in primary immune deficiencies and hematopoietic cell transplantation is a perfect fit. My practice combines my love of immunology with caring for pediatric patients and working in a team-based setting.
As an immunologist and transplant physician, I treat patients with primary immune deficiencies and immune regulatory diseases, which are collectively called inborn errors of immunity. I’m the clinical director of the Primary Immune Deficiency Program and co-director of Diagnostic Immunology Laboratory.
Our practice provides a variety of treatments for patients, including allogeneic hematopoietic cell transplantation. Each patient and family is different, and I enjoy getting to know each person and helping them live their best life through optimal treatment of their immune deficiency.
We have a large group of specialists in the diagnosis and treatment of inborn errors of immunity. We also have the largest clinical laboratory specializing in primary immunodeficiency diagnostics. Our physician group consists of several experts in primary immunodeficiencies. Our physicians not only provide state-of-the-art treatment for patients, but they also lead the field with primary immune deficiency research and new treatment trials.
We have many nurse practitioners dedicated to caring for patients with inborn errors of immunity. Patients in our practice also work with a dedicated nurse coordinator who helps patients navigate their medical care. Our practice is special because we provide cutting-edge diagnostics and treatments for our patients and also maintain a supportive and caring team-based environment.
Through my research, I want to improve allogeneic hematopoietic cell transplantation for patients with primary immunodeficiencies. I’m also working to improve the treatment of patients with X-linked inhibitor of apoptosis (XIAP) deficiency and hemophagocytic lymphohistiocytosis (HLH).
In my free time, I like to play the piano, bake and spend time with my family.
BS: University of Tennessee, Knoxville, TN, 1998.
MD: Rush Medical College, Chicago, IL, 2003.
Residency: Rush University Medical Center, Chicago, IL, 2006.
Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2008.
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STAT6 gain-of-function disease: p.D519N is a new disease-causing variant that responds well to dupilumab treatment. Journal of Allergy and Clinical Immunology: Global. 2025; 4:100494.
Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) functional deficiency caused by biallelic LRBA missense variants characterized by Evans syndrome or colitis. Journal of Allergy and Clinical Immunology. 2025; 156:270-278.
Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants. Blood. 2025; 145:2992-3006.
Clinical, Immunologic, and Genetic Characteristics in Patients With Syndrome of Undifferentiated Recurrent Fevers. Arthritis and Rheumatology. 2025; 77:596-605.
Lung Disease in Systemic Juvenile Idiopathic Arthritis: An Atypical Path to Diagnosis. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7865.
Experience with T Cell–Depleted Allogeneic HSCT for Refractory sJIA Associated with Lung Disease. 2025; 1.
Relevance of Recent Thymic Emigrants Following Allogeneic Hematopoietic Cell Transplantation for Pediatric Patients with Inborn Errors of Immunity. Transplantation and Cellular Therapy. 2025; 31:265.e1-265.e12.
Allogeneic haematopoietic stem-cell transplantation for children with refractory systemic juvenile idiopathic arthritis and associated lung disease: outcomes from an international, retrospective cohort study. The Lancet. Rheumatology. 2025; 7:e243-e251.
Comprehensive flow cytometry-based diagnosis of XIAP deficiency. Clinical and Experimental Immunology. 2025; 219:uxaf020.
Hematopoietic Cell Transplantation for Wiskott-Aldrich Syndrome - Impact of Age, Donor, and Infection: A Pidtc Report. Transplantation and Cellular Therapy. 2025; 31:s39-s41.
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