A photo of Joseph Palermo.

Joseph J. Palermo, MD, PhD

  • Director, Gastroenterology Center of Excellence
  • Assistant Professor, UC Department of Pediatrics
I strive to help families and patients manage their health through education, while we navigate the investigation and treatment options that will provide the best possible outcome.



I knew early on that I was interested in pediatrics and working with children and their families. Gastroenterology drew me in because of its breadth of diagnoses and the body systems involved. The gastroenterology attending I worked with during my intern year of residency solidified my decision.

My general pediatric gastroenterology and nutrition practice focuses on conditions such as inflammatory bowel disease, celiac disease and the gastrointestinal (GI) manifestations of cystic fibrosis, including cystic fibrosis liver disease. I also treat patients with Fontan-associated liver disease and intestinal polyposis syndromes including familial adenomatous polyposis.

I strive to help families and patients manage their health through education, while we navigate the investigation and treatment options that will provide the best possible outcome. My patients’ and families’ concerns are my concerns.

In association with the Cystic Fibrosis Foundation, my research focuses on the pathophysiology of liver disease that is associated with other chronic conditions, such as cystic fibrosis or congenital heart disease.

In my free time, I enjoy woodworking and coaching my children in soccer and baseball.

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Health-related quality of life in a prospective study of ultrasound to detect cystic fibrosis-related liver disease in children. Schwarzenberg, SJ; Palermo, JJ; Ye, W; Huang, S; Magee, JC; Alazraki, A; Freeman, AJ; Harned, R; Karmazyn, B; Karnsakul, W; et al. Journal of Pediatric Gastroenterology and Nutrition. 2022.

Long-term follow-up and liver outcomes in children with cystic fibrosis and nodular liver on ultrasound in a multi-center study. Leung, DH; Ye, W; Schwarzenberg, SJ; Freeman, AJ; Palermo, JJ; Weymann, A; Alonso, EM; Karnsakul, WW; Murray, KF; Stoll, JM; et al. Journal of Cystic Fibrosis. 2022.

Abdominal CT and MRI Findings of Portal Hypertension in Children and Adults with Fontan Circulation. Zafar, F; Lubert, AM; Trout, AT; Katz, DA; Palermo, JJ; Opotowsky, AR; Lorts, A; Chin, C; Powell, AW; Villa, CR; et al. Radiology. 2022; 303:557-565.

Relation of Liver Volume to Adverse Cardiovascular Events in Adolescents and Adults With Fontan Circulation. Lubert, AM; Opotowsky, AR; Palermo, JJ; Alsaied, T; Szugye, C; Anwar, N; Tiao, GM; Lorts, A; Dillman, JR; Trout, AT. American Journal of Cardiology. 2022; 165:88-94.

Developing an adolescent and adult Fontan Management Programme. Lubert, AM; Alsaied, T; Trout, AT; Dillman, JR; Palermo, JJ; Eichelbrenner, F; Kleier, K; Lorts, A; Anwar, N; Schecter, MG; et al. Cardiology in the Young. 2022; 32:230-235.

Relation of Magnetic Resonance Elastography to Fontan Circulatory Failure in a Cohort of Pediatric and Adult Patients. Brayer, SW; Zafar, F; Lubert, AM; Trout, AT; Palermo, JJ; Opotowsky, AR; Anwar, N; Dillman, JR; Alsaied, T. Pediatric Cardiology. 2021; 42:1871-1878.

Association Between Transient Elastography and Controlled Attenuated Parameter and Liver Ultrasound in Children With Cystic Fibrosis. Ye, W; Leung, DH; Molleston, JP; Ling, SC; Murray, KF; Nicholas, JL; Huang, S; Karmazyn, BW; Harned, RK; Masand, P; et al. Hepatology Communications. 2021; 5:1362-1372.

MELD-XI score is not associated with adverse outcomes in ambulatory adults with a Fontan circulation. Aldweib, N; Wei, C; Lubert, AM; Wu, F; Valente, AM; Alsaied, T; Assenza, GE; Eichelbrenner, F; Palermo, JJ; Landzberg, MJ; et al. International journal of cardiology congenital heart disease. 2021; 4.

Hepatic Steatosis in Patients With Single Ventricle and a Fontan Circulation. Katz, DA; Peck, D; Lubert, AM; Possner, M; Zafar, F; Trout, AT; Palermo, JJ; Anwar, N; Dillman, JR; Powell, AW; et al. Journal of the American Heart Association. 2021; 10.

Fontan-Associated Dyslipidemia. Lubert, AM; Alsaied, T; Palermo, JJ; Anwar, N; Urbina, EM; Brown, NM; Alexander, C; Almeneisi, H; Wu, F; Leventhal, AR; et al. Journal of the American Heart Association. 2021; 10.

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