Grant Schulert, MD, PhD

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4676

Email grant.schulert@cchmc.org

Clinical

Pediatric rheumatology; juvenile idiopathic arthritis; macrophage activation syndrome; autoinflammatory syndromes; periodic fevers

Research

Systemic JIA; macrophage activation syndrome; innate immunity; monocyte and macrophage functions; whole exome sequencing
Visit the Schulert Lab

MD: University of Iowa College of Medicine, Iowa City, IA, 2009.

PhD: University of Iowa Department of Microbiology, Iowa City, IA, 2009.

Residency: Pediatrics, Vanderbilt University Medical Center, Nashville, TN.

Fellowship: Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, 2012.

View PubMed Publications

Bracaglia C, de Graaf K, Marafon DP, D’Ario G, Guilhot F, Ferlin W, Prencipe G, Caiello I, Davi S, Schulert G, Ravelli A, Grom A, De Min C, De Benedetti F. Elevated circulating levels of interferon-gamma and interferon-gamma related chemokines characterize patients with macrophage activation syndrome complicating systemic JIA. Ann Rheum Dis. 2016.

Schulert GS, Fall N, Harley J, Shen N, Lovell DJ, Thornton S, Grom AA. Monocyte microRNA expression in active systemic juvenile idiopathic arthritis reveals key role of miR-125a-5p in polarized monocyte phenotypes. Arthritis Rheumatol. 2016;68:2300-2313.

Favier LA, Schulert GS. Mevalonate kinase deficiency – current perspectives. App Clin Genet. 2016;9:93-100. 

Schulert GS, Grom AA. Pathogenesis of macrophage activation syndrome and potential for cytokine- directed therapies. Annu Rev Med. 2015;66:145-59.

Schulert GS, Zhang M, Fall N, Husami A, Kissell D, Hanosh A, Zhang K, Davis K, Jentzen JM, Napolitano L, Siddiqui J, Smith LB, Harms PW, Grom AA, Cron RQ. Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza. J Infect Dis. 2015 Nov 23.

Schulert GS, Bove K, McMasters R, Campbell K, Leslie N, Grom AA. 11-Month-Old Infant With Periodic Fevers, Recurrent Liver Dysfunction, and Perforin Gene Polymorphism. Arthritis Care Res (Hoboken). 2015 Aug;67(8):1173-9.

Schulert GS, Graham TB. Chronic inflammatory arthritis of the ankle/hindfoot/midfoot complex in children with extreme obesity. J Clin Rheumatol. 2014 Sep;20(6):317-21.

Schulert GS, McCaffrey RL, Buchan BW, Lindemann SR, Hollenback C, Jones BD, Allen LA. Francisella tularensis genes required for inhibition of the neutrophil respiratory burst and intramacrophage growth identified by random transposon mutagenesis of strain LVS. Infect Immun. 2009 Apr;77(4):1324-36.

Schulert GS, Allen LA. Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor. J Leukoc Biol. 2006 Sep;80(3):563-71.

Schulert GS, Feltman H, Rabin SD, Martin CG, Battle SE, Rello J, Hauser AR. Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia. J Infect Dis. 2003 Dec 1;188(11):1695-706. Epub 2003 Nov 21.

Monocyte and macrophage polarization in systemic juvenile idiopathic arthritis and macrophage activation syndrome. Principal Investigator. Cincinnati Children's Hospital Medical Center Procter Scholar Award. Jul 2016-Jun 2018. 

Contribution of microRNA to aberrant monocyte activation and polarization in systemic juvenile idiopathic arthritis. Principal Investigator. Rheumatology Research Foundation. Jul 2015-Jun 2017.