Dr. Spooner practices general academic pediatrics and serves as the Chief Medical Information Officer for Cincinnati Children’s. He is also actively involved in patient-centered research. He and his research group have created a data warehouse focusing on medication alerts stretching back five years, into which they have built several metrics of user alert-response behavior. They are using this warehouse to answer questions about how clinical users manage the load of decision-support alerts in the system and how they detect potential harmful overdose errors. They are collaborating with an external machine-learning vendor that is working with the hospital’s safety leaders on safety analytics to bring more powerful tools to bear on the problem of alert fatigue and user overload. On other fronts, Dr. Spooner is researching decision support for weight data-entry errors that can have profound effects on medication safety. His group is working with business intelligence systems interfaced to the electronic medical record to tune decision support to unprecedented specificity and sensitivity.