A photo of Sonya Tang Girdwood.

Sonya Tang Girdwood, MD, PhD


  • Member, Division of Hospital Medicine
  • Member, Division of Translational and Clinical Pharmacology
  • Assistant Professor, UC Department of Pediatrics
Today, my clinical work informs my research so that any newly discovered information can impact my patient’s care.
Sonya Tang Girdwood, MD, PhD

About

Biography

I chose to specialize in hospital medicine because it allows me to collaborate with other subspecialties in the care of pediatric patients. I enjoy the acute-care aspect of hospital medicine and have the opportunity to develop relationships with the families of children with medically complex illnesses admitted to our inpatient unit.

Early on, I realized information regarding appropriate drug dosing in medically complex or critically ill children was lacking. So, my research explores how to personalize the dosing of antibiotics and other medications in critically ill patients and patients with complex diseases.

I focus on the pharmacokinetics and pharmacodynamics of antibiotics, specifically beta-lactams, in critically ill children. Additionally, I strive to better understand the timely transition of intravenous to enteral antibiotics in hospitalized children. Today, my clinical work informs my research so that any newly discovered information can impact my patient’s care.

As a clinical fellow, I received several notable awards, including:

  • Cincinnati Children’s Hospital Medical Center Arnold Strauss Fellow Award
  • Cincinnati Children’s Hospital Medicine Fellow Award
  • Gerber Foundation Research Novice Award

As a faculty member, in addition to serving on the American Society of Clinical Pharmacology and Therapeutics Career Development Committee, I am also a member of their Scientific Programming Committee for the national conference. Locally, I am a co-director of the Genetic Pharmacology Service and the T32 Pediatric Clinical Pharmacology Fellowship.

During my first two years on faculty, I was supported by the National Institute of Child Health and Human Development (NICHD) K12 Child Health Research Career Development Award to study the impact of piperacillin/tazobactam pharmacokinetics on kidney injury. I’m currently funded by a National Institute of General Medicine Sciences (NIGMS) R35 Maximizing Investigators' Research Award to continue building the evidence of precision dosing of antibiotics in critically ill children.

BS: Massachusetts Institute of Technology, Cambridge, MA, 2004.

MD: Johns Hopkins University, Baltimore, MD, 2013.

PhD: Johns Hopkins University, Baltimore, MD, 2013.

Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2016.

Chief Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2017.

Fellowship: Pediatric Hospital Medicine & T32 NICHD Clinical Pharmacology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2020.

Interests

Hospital medicine; complex care inpatient team

Services and Specialties

Hospital Medicine, Genetic Pharmacology, Genetic Pharmacology Service

Interests

Pediatric clinical pharmacology; sepsis; model-informed precision dosing; IV to enteral antibiotic transition

Research Areas

Clinical Pharmacology

Publications

868: EARLY MEROPENEM CLEARANCE OF CRITICALLY ILL PATIENTS IN A PEDIATRIC INTENSIVE CARE UNIT. Paice, K; Tang Girdwood, S; Pavia, K; Mizuno, T; Kaplan, J. Critical Care Medicine. 2024; 52:s407.

Professionalism or prejudice? Modelling roles, risking microaggressions. Miller, E; Girdwood, ST; Shah, A; Anyigbo, C; Lanphier, E. Journal of Medical Ethics. 2023; 49:822-823.

Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing. Taylor, ZL; Poweleit, EA; Paice, K; Somers, KM; Pavia, K; Vinks, AA; Punt, N; Mizuno, T; Girdwood, ST. CPT: Pharmacometrics and Systems Pharmacology. 2023; 12:1827-1845.

Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy. Cervantes, FC; Mizuno, T; Dong, M; Tang, P; Arbough, T; Vinks, AA; Kaplan, JM; Tang Girdwood, SC. Therapeutic Drug Monitoring. 2023; 45:832-836.

Current Practices in Pharmacogenomics. Ramsey, LB; Prows, CA; Tang Girdwood, S; Van Driest, S. Pediatric Clinics of North America. 2023; 70:995-1011.

Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy. Pavia, K; Hambrick, HR; Paice, K; Tang, P; Punt, N; Kaplan, J; Goldstein, SL; Vinks, AA; Mizuno, T; Tang Girdwood, S. Journal of Antimicrobial Chemotherapy. 2023; 78:2140-2147.

Polypharmacy among medicaid-insured children with and without documented obesity. Kyler, KE; Hall, M; Antoon, JW; Goldman, J; Grijalva, CG; Shah, SS; Tang Girdwood, S; Williams, DJ; Feinstein, JA. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023; 43:588-595.

Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center. Ramsey, LB; Prows, CA; Chidambaran, V; Sadhasivam, S; Quinn, CT; Teusink-Cross, A; Tang Girdwood, S; Dawson, DB; Vinks, AA; Glauser, TA. American Journal of Health-System Pharmacy. 2023; 80:852-859.

Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone. Tang Girdwood, S; Tang, P; Fenchel, M; Dong, M; Stoneman, E; Jones, R; Ostermeier, A; Curry, C; Forton, M; Hail, T; et al. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023; 43:609-621.

Guideline-Concordant Antiviral Treatment in Children at High Risk for Influenza Complications. Antoon, JW; Hall, M; Feinstein, JA; Kyler, KE; Shah, SS; Girdwood, ST; Goldman, JL; Grijalva, CG; Williams, DJ. Clinical Infectious Diseases. 2023; 76:e1040-e1046.

From the Blog

PAS 2022: Exactly What My Soul Needed
Community Health

PAS 2022: Exactly What My Soul Needed

Sonya Tang Girdwood, MD, PhD5/2/2022

Growing Need for Pharmacogenetics Data for Pediatric Medications
Quality and Safety

Growing Need for Pharmacogenetics Data for Pediatric Medications

Sonya Tang Girdwood, MD, PhD3/9/2022

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