A photo of Katherine VandenHeuvel.

Katherine A. VandenHeuvel, MD


  • Staff Pathologist, Division of Pathology
  • Assistant Professor, UC Department of Pathology and Laboratory Medicine
  • UC Department of Pediatrics
My approach to my practice is to balance information with compassion. Even though I do not meet many patients face-to-face, I look at each specimen as a unique opportunity to provide them, their family and their doctors with timely and accurate information.

About

Biography

I've always loved children and appreciated the unique medical conditions and needs they have. I grew up with a chronic disease that had me regularly interacting with healthcare providers, particularly pediatricians and pediatric specialists.

In the field of pathology, I focus on getting the best diagnostic information for each individual patient. Every day, my colleagues and I guide the approach to treatment with our findings. My approach to my practice is to balance information with compassion. Even though I do not meet many patients face-to-face, I look at each specimen as a unique opportunity to provide them, their family and their doctors with timely and accurate information.

I am a pediatric surgical pathologist with a specific focus on pediatric renal and neuroblastic tumors and renal pathology. I love having a specialty like renal pathology because it allows me to form a personal relationship with one set of clinicians — nephrologists — and to follow the course of a patient's condition over time.

Kidney biopsy diagnosis requires some special techniques, such as electron microscopy and fluorescent staining, that very few other biopsies need. Although these techniques take extra time, I'm in contact with the patient’s kidney doctors every step of the way.

My research involves understanding and treating kidney injuries that are related to sickle cell disease. We want to clarify the genes expressed in individual cells of the same Wilms tumor and how widely different they can be. We’re exploring how what we know about membranous nephropathy in adults also fits the disease in children.

In my free time, I enjoy singing with the Young Professionals Choral Collective here in Cincinnati. I performed in the student musical every year in medical school. In an alternate life, I would have been a librarian.

Publications

Olfactomedin 4 as a novel loop of Henle-specific acute kidney injury biomarker. Hasson, DC; Krallman, K; VanDenHeuvel, K; Menon, S; Piraino, G; Devarajan, P; Goldstein, SL; Alder, M. Physiological Reports. 2022; 10.

Multiparametric quantitative renal MRI in children and young adults: comparison between healthy individuals and patients with chronic kidney disease. Dillman, JR; Benoit, SW; Gandhi, DB; Trout, AT; Tkach, JA; VandenHeuvel, K; Devarajan, P. Abdominal Radiology. 2022; 47:1840-1852.

Case Report: Atypical HUS Presenting With Acute Rhabdomyolysis Highlights the Need for Individualized Eculizumab Dosing. Benoit, SW; Fukuda, T; VandenHeuvel, K; Witte, D; Fuller, C; Willis, J; Dixon, BP; Drake, KA. Frontiers in Pediatrics. 2022; 10.

Primary hyperoxaluria diagnosed after kidney transplant: A review of the literature and case report of aggressive renal replacement therapy and lumasiran to prevent allograft loss. Stone, HK; VandenHeuvel, K; Bondoc, A; Flores, FX; Hooper, DK; Varnell, CD. American Journal of Transplantation. 2021; 21:4061-4067.

A mutant fibrinogen that is unable to form fibrin can improve renal phenotype in mice with sickle cell anemia. Narciso, MG; Hoeting, B; James, JM; VandenHeuvel, K; Nasimuzzaman, M. 2021; 2:462-465.

Metastatic neuroblastoma masquerading as infantile hemangioma in a 4-month-old child. Karkoska, K; Ricci, K; VandenHeuvel, K; Trout, AT; Smith, EA; Kotagal, M; Weiss, B. Pediatric Blood and Cancer. 2021; 68.

Glomerulonephritis in Youth With Dystrophic Epidermolysis Bullosa. Hughley, E; Nehus, EJ; VandenHeuvel, K; Augsburger, BD; Jain, NG; Lucky, AW. Kidney International Reports. 2021; 6:538-543.

Elimination of the fibrinogen integrin αMβ2-binding motif improves renal pathology in mice with sickle cell anemia. Nasimuzzaman, M; Arumugam, PI; Mullins, ES; James, JM; VandenHeuvel, K; Narciso, MG; Shaw, MA; McGraw, S; Aronow, BJ; Malik, P. Blood Advances. 2019; 3:1519-1532.

Angiotensin receptor signaling in sickle cell anemia has a reno-protective effect on urine concentrating ability but results in sickle glomerulopathy. Roy, S; Rai, P; Mpollo, ME M; Chang, K; Rizvi, T; Shanmukhappa, SK; VandenHeuvel, K; Aronow, B; Inagami, T; Cancelas, JA; et al. American Journal of Hematology. 2018; 93:E177-E181.

A Novel Presentation of Littoral Cell Angioma and Lymphatic Malformations in a Neonate. Gakenheimer-Smith, L; Mohlman, J; VandenHeuvel, K; Jackson, WD; Thomsen, W; Stevenson, A; Cipriano, F. Pediatrics. 2018; 141:S520-S525.

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