Pediatric Oncologic Pathology
Our Pediatric Oncologic Pathology services provide comprehensive diagnostic evaluation and consultation for benign and malignant solid tumors across all age groups, from the perinatal period to adolescence and young adulthood (AYA), and for selected entities, into middle-age. We incorporate advanced molecular tumor genetics data into primary diagnoses and contribute to treatment planning by aligning pathology with imaging and clinical outcomes. Our division actively supports national clinical trials and research studies conducted at Cincinnati Children’s.
Collaborative Centers
We work in partnership with surgical oncology, orthopedic surgery, bone marrow transplantation, radiology, and pediatric oncology teams at the Cancer and Blood Diseases Institute (CBDI). Our service is also involved in COG clinical trials, providing centralized pathology support for rare and high-risk tumor entities.
Consultative Service
We provide consultative diagnostic services for biopsies and resections involving bone, soft tissue, and other pediatric solid tumors. Our evaluations integrate histologic features with immunohistochemical, molecular, and cytogenetic findings to achieve accurate classification. Our pathologists actively participate in multidisciplinary tumor boards, helping guide individualized treatment planning. We accept consultative specimens from internal and external sources, including pre-prepared slides and tissue referred for interpretation, staining, or ultrastructural analysis.
Areas of Expertise
- Rhabdomyosarcoma
- Nonrhabdomyosarcomatous soft tissue tumors
- Neuroblastoma, paraganglioma, pheochromocytoma, and adrenal cortical tumors
- Endocrine tumors of thyroid, pancreas, adrenals
- Renal tumors: Wilms tumor, RCC, renal sarcomas
- Germ cell tumors (ovary/testis), stromal tumors of GU tract
- Head and neck tumors: orbit, sinuses, salivary glands
- Pediatric melanocytic lesions (e.g., Spitz nevi), stromal/vascular tumors, hamartomas
- Tumors associated with genetic syndromes
- Hepatoblastoma and pediatric liver tumors
- Germ cell tumors
- Rare tumors of infancy and early childhood
- Small cell carcinoma of the ovary
For more information about our services, contact us.
