Eosinophilic esophagitis (EoE) is a rare disease of the esophagus. The esophagus is the tube that connects the mouth to the stomach. With EoE, there are a large number of white blood cells called eosinophils in the esophagus. These cells can cause injury and irritation to the esophagus.

EoE affects people of all ages. Both males and females get EoE, but it is more common in males. People with EoE commonly have other allergic conditions such as rhinitis (runny nose), asthma, and/or eczema (skin rashes).