Eosinophilic Disorders in the News

The Cincinnati Center for Eosinophilic Disorders (CCED) at Cincinnati Children's offers links to radio shows and other recent news coverage on eosinophilic disorders. 

Info on COVID-19

Get updated information about the novel coronavirus (COVID-19) and how it affects patients with eosinophilic conditions. Read more.

August 11

Pollution to pollen, floods to fires: how does climate change affect children with sensitive skin? (Episode 23)

August 5

The Beginning of a New Medication From Recognizing a Need to FDA Approval: Dr. Rothenberg on the Young and Healthy Podcast

August 2

Vitamin D Supplementation Alleviates IL-13–Induced Esophageal Inflammation

August 1

Cincinnati Children's - Bridge to Next-Gen Medicine Collaboration Selects 4 Projects for Pilot Funding

July 25

Patients with eosinophilic esophagitis symptoms may benefit from gastric emptying studies

July 14

Dupixent® (Dupilumab) Phase 3 Trial Shows Positive Results in Children 1-11 Years of Age With Eosinophilic Esophagitis

July 13

Marc Rothenberg selected as the 2023 recipient of the AAAAI Distinguished Scientist Award

July 8

New Treatment Gives Hope to Those with Eosinophilic Esophagitis

July 7

Journal Devotes Cover to Eosinophilic Esophagitis Research

July 6

CEGIR: Online Communities Illuminate Needs and Goals of Patients with Eosinophilic Esophagitis

June 27

Development of Outcome Metrics Leads to First FDA-Approved Treatment for Eosinophilic Esophagitis

June 10

Young and Healthy Podcast: 2022 Formula Shortage: Update for Families

June 9

Why Your Child Most Likely Does Not Have A Penicillin Allergy

June 8

NORD Applauds House Passage of H.R. 7667, the Food and Drug Amendments of 2022

June 7

FDA Approves Dupilumab for Children With Eczema Aged 6 Months to 5 Years

June 2

Q&A: Dupilumab Approved for EoE, Plus Hope for More Therapies

June 1

Q&A: FDA approval of dupilumab for eosinophilic esophagitis a ‘victory for rare diseases’

May 26

FDA Approval of Dupilumab Celebration at Cincinnati Children's

May 20

First Treatment for Eosinophilic Esophagitis Wins FDA Approval

May 20

FDA Approves First Treatment for Eosinophilic Esophagitis, a Chronic Immune Disorder

May

One Family’s Story about Penicillin Allergy Testing

May 17

Scientists Making Progress Against a Severe Form of Food Allergy

May 17

What to Expect from Your Nasal Endoscopy Video

May 15

Highlights of Eosinophilic Disease-Related Research (May 2021-2022)

May 15

Message on National Eosinophilic Awareness Week: CEGIR Administrative Director

May 15

Message on National Eosinophilic Awareness Week: CEGIR Principal Investigator

May 1

May Cover of Gastroenterology: Transcriptome-Based Analysis Offers Insight Into Eosinophilic Colitis as a Distinct Disease Entity

May

2022 Scholar Day Presentation by Marc Rothenberg, MD, PhD

April 21

Eosinophilic Esophagitis (NORD) Video

April 21

Cures Within Reach seeks clinical trials in health disparities or led by underserved researchers

April 15

Young and Healthy Podcast: Plant-based Milk Alternatives and Kids

April 4

FDA accepts Dupixent® (dupilumab) for Priority Review in patients aged 12 years and older with eosinophilic esophagitis

March 24

New Federal Spending Bill Also Helps Food Allergic School Children

March 22

Earlier and Longer Pollen Seasons Due to Climate Change Expected to Impact Allergic Diseases

March 16

Climate Change Cited as Cause of Recent Increases in Asthma Allergy Prevalence

March 11

Cincinnati Children’s, UC College of Medicine Become a World Allergy Organization Center of Excellence

February 13

Building a Community to Change the Outcome Together Through Research

February 1

Children with High-Risk Reaction Histories to Penicillin Can Undergo Direct Oral Penicillin Challenges

January

World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update – I – Plan and definitions
Since the World Allergy Organization (WAO) Diagnosis and Rationale against Cow's Milk Allergy (DRACMA) Guidelines were published 10 years ago, new evidence has accumulated about the diagnosis, therapy, and specific immunotherapy for cow's milk allergy (CMA). For this reason, WAO has felt the need to update the guidelines. Thank you to our local colleague, Amal H. Assa'ad, MD, for her dedicated work as part of the WAO DRACMA guideline group!

January 26

Community Access Funding to Focus on Increasing Diverse Engagement in Food Allergy Research

January 26

Molecular Analysis Suggests Eosinophilic Colitis is a Unique Disease

January 24

Cincinnati Magazine Top Doctors of 2022

We are so proud of our CCED physicians. Congratulations to Drs. Marc Rothenberg (Allergy/Immunology), Vincent Mukkada (Gastroenterology), and Philip Putnam (Gastroenterology) for being recognized as Top Doctors 2022 by Cincinnati Magazine.

January 13

CEGIR Researchers Report on the FDA Workshop: Challenges, Progress, Questions in Eosinophilic Gastrointestinal Disorders

January

Allergic to Penicillin? Don't Make Rash Judgments

January 7

Preparing for Progress on Eosinophilic Gastrointestinal Diseases Beyond Eosinophilic Esophagitis

November 29

Remote immune processes revealed by immune-derived circulating cell-free DNA

Marc Rothenberg, MD, PhD and his team are collaborating with Israeli scientists to develop non-invasive biomarkers for eosinophilic esophagitis (EoE); in this publication, they describe recent findings in their pursuit to develop an EoE blood test.

November 23

Two Genes Associated with Familial EoE

October

2021 STAT Wunderkind Award to Tetsuo Shoda

October

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Video

October 25

Artificial Intelligence Holds the Key to Diagnosing Rare Esophageal Food Allergy Disease

October 25

Second DUPIXENT® (Dupilumab) Phase 3 Eosinophilic Esophagitis Trial To Demonstrate Significant Disease Improvements, Underscoring Role of Type 2 Inflammation in This Complex Disease

“It is exciting to see this continual positive data, especially knowing that the foundation for this therapy was derived from our long term research focus deciphering the role of type 2 immunity (IL-13) in Eosinophilic Esophagitis and other related diseases." ~Marc Rothenberg, MD, PhD

October 21

Cincinnati Children’s Launching Collaboration with Technion-Israel Institute of Technology

October 20

FDA expands approval of Dupixent® (dupilumab) to include children aged 6 to 11 years with moderate-to-severe asthma

October 13

Neonatal Antibiotics Disrupt Esophageal Microbiota, May Increase Risk of EoE

October 13

Groundbreaking partnership combines Israeli technological prowess with pediatric medicine

September 16

Discovery of Rapid-Response Signaling Platform Suggests New Path for Blocking Allergic Inflammation

September 14

Recognized as an Expertscape World Expert in Granulocytes

Expertscape's PubMed-based algorithms placed Marc Rothenberg, MD, PhD in the top 0.1% of scholars writing about Granulocytes over the past 10 years, a level that Expertscape labels as "World Expert."

September

Melanie Uses Pageant Platform to Share Her Story and Build Eosinophilic Esophagitis Awareness

September 1

Bridge to Next-Gen Medicine

August 13

Summer Undergraduate Research Fellowship Awardee

Congratulations to Andrea for winning 2nd place for her Summer Undergraduate Research Fellowship (SURF) presentation! This presentation was based on the research that Andrea conducted in the Rothenberg CURED Lab through the SURF Medical Exploration program. Under the mentorship of Julia Dunn, PhD and Marc Rothenberg, MD, PhD, Andrea investigated gene expression patterns of eosinophils in patients with eosinophilic esophagitis.

August 12

NIH LRP Awardees

Congratulations to Assistant Professor Ashley L. Devonshire, MD, MPH and third-year clinical fellow Simin Zhang, MD, for being recognized for their excellence with awards from a Loan Repayment Program (LRP) of the National Institutes of Health! The NIH LRPs are a set of programs established by Congress and designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers. The escalating costs of advanced education and training in medicine and clinical specialties are forcing some scientists to abandon their research careers for higher-paying private industry or private practice careers. The LRPs counteract that financial pressure by repaying up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research and are highly competitive. Drs. Devonshire and Zhang continue the strong showing of the Division of Allergy and Immunology in having NIH LRP recipients, including prior NIH LRP awards to Drs. Michael G. Sherenian, MD, MS, Steve P. Proper, DO, PhD, and Joseph Sherrill, PhD. Since tomorrow's medical breakthroughs will be made by investigators starting in their research careers today, the LRPs represent an important investment by NIH in the future of health discovery and the wellbeing of the Nation and represent recognition of an investigator's potential. Dr. Devonshire is currently researching food allergy and food allergy risk in infants. Dr. Zhang is currently researching mast cell involvement and functions in eosinophilic esophagitis under the mentorship of Marc Rothenberg, MD, PhD and J. Pablo Abonia, MD.

August 2

Irritable Bowel Syndrome and the Food Allergy Connection

“Common gastrointestinal ailments, such as irritable bowel syndrome (IBS) and functional abdominal pain, may instead be food-induced allergic disorders,” says our Cincinnati Children's Center for Pediatric Genomics awardee Marc Rothenberg, MD, PhD in the NY Times

July 19

Less Restrictive Diet for Adult EoE with Milk Trigger: Some Adults with EoE Allergy Can Just Cut Milk, Instead of 6 Foods

July 12

Care Providers Read Patient Comments from Experience Surveys: Vincent Mukkada

 At Cincinnati Children's, our caregivers go above and beyond each day to give patients the best experience possible. Hear how they, including Vincent Mukkada, MD (Gastroenterology), react to meaningful words straight from their patient families.

July 5

EoE: the Food Allergy Disease

June 21

Eosinophilic Asthma: What Doctors Need You to Know

June 16

Artificial Intelligence in Allergy/Immunology Transformative machine learning in diagnosing eosinophilic esophagitis (EoE)

June 10

Man Undergoing Treatment of Rare Genetic Condition Graduates College 2,500 Miles Away From Home Decoding the Mysteries of Postural Orthostatic Tachycardia Syndrome
This is encouraging news for all of our patients and families effected by the combination of postural orthostatic tachycardia syndrome (POTS) and eosinophilic gastrointestinal disorders (EGIDs).

April 1
Congratulations to the two Cincinnati Children's and University of Cincinnati Allergy / Immunology fellows for being recognized with first and second place in clinical research at the 10th Annual Department of Internal Medicine Research Symposium. Simin Zhang, MD was awarded 1st for her project “Clinical Significance of Mast Cell Density in GI Biopsies in Patients Presenting for Evaluation of GI Mast Cell Disorders”, and David Adams, PhD was awarded 2nd place for his project: "Multifactorial Regulation of Axl Expression".

March
Who We Are: Rare Diseases Clinical Research Network Video

February 22
Cincinnati Children’s Team and Faculty Awards
Allergy Nursing Team recognized as the “2020 Top Performing Small Division for Outstanding Nursing Patient Family Experience (PFE)”! This honor was awarded based on a review of the annual experience survey scores and positive comments, which highlight the exceptional feedback the team routinely receives from the patients and families. The team was recognized in a virtual awards ceremony held on Monday, February 22nd. Thank you for all you do, for making a difference in the lives of so many families and for promoting a positive experience at Cincinnati Children’s!

Vincent Mukkada, MD received the “2020 Top Pediatric Provider Award” at Cincinnati Children’s! This is an amazing, well-deserved accomplishment, reflecting not only his outstanding clinical care, but also a great team at large with the Division of Gastroenterology, Hepatology and Nutrition and the Cincinnati Center for Eosinophilic Disorders.

Kimberly Risma, MD, PhD received the “2020 Clinical Care Achievement Award”! Dr. Risma is an extraordinary clinician whose innovation has led to the creation of the Drug Allergy Program launched in 2019. She is also having a leading impact in promoting the next generation of physicians in the allergy and immunology field. This award is most deserving and demonstrates appreciation for her immense dedication, talents and contributions.

February 11
2020 Research Highlights: Division of Allergy and Immunology

February 11
RDCRN Announces New 2021 Network Steering Committee Leadership
We are pleased to announce that Marc Rothenberg, MD, PhD has been elected as co-chair of the Rare Diseases Clinical Research Network (RDCRN, www.rarediseasesnetwork.org) Steering Committee. Dr. Rothenberg will join Dr. Jennifer Puck and Dr. Andrea Gropman in leading the RDCRN Steering Committee.

January 21
Cincinnati Children’s to House Food Allergy Biobank and Biomarker Discovery Center

January 21
FARE Announces Key Partnerships in Crusade to Advance Food Allergy Research

January 14
Scientist Spotlight: Marc Rothenberg Leads Eosinophilic Collaboration and Research to New Discoveries

January 13 
EoE Research Selected as ‘Editor’s Choice’ in JACI

January 6
How Experts at Cincinnati Children's Hospital Medical Center are Combatting Allergic Reactions

December

U.S. Senate Passes FASTER Act, Brings Sesame Labeling One Step Closer for Food Allergy Community

November

Transferring Allergies in the Womb
Dr. Rothenberg shares his perspective on a recent article about how maternal mast cells are involved in allergy development in this invited Science Perspective.

Asian Children With Food Allergies More Likely to Experience Quality of Life Challenges

MSSRP Poster Award Winners
Susie Min and Rahul Sandella participated in the 10th Annual Research and Service Symposium at UC on Friday, November 6th. We appreciate UC providing a virtual forum for the MSSRP Program poster judging this year. Susie Min won second place for "Molecular Diagnosis of Eosinophilic Esophagitis from a Single Esophageal Biopsy" with the mentorship of Ting Wen, PhD and Marc Rothenberg, MD, PhD. She will represent us at the annual National Student Research Forum (NSRF) in Galveston, TX (April, 2021). Rahul Sandella won third place for "The Effects of Adiposity on Disease and Symptom Severity in Eosinophilic Esophagitis" with the mentorship of Vincent A. Mukkada, MD and Kara Kliewer, RD, PhD.

October

Grateful Patient with Eosinophilia Thanks Cincinnati Children’s For Improved Life

Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis
Patients with eosinophilic gastritis (EG) have limited therapeutic options. The Cincinnati Center for Eosinophilic Disorders is proud to have been an integral part of an important trial, now published in the New England Journal of Medicine, demonstrating that lirentelimab significantly and safely improves symptoms in subjects with EG while eradicating eosinophils. We are hopeful that the Phase 3 trial, which is now enrolling participants, will ultimately confirm these findings so that there are more clinically approved therapeutic options for individuals with this rare disorder.

September

Roots of New Drug for HES Trace Back to Cincinnati Children’s

Cincinnati Children's helps pave way for newly approved use of drug 

What is Eosinophilia?

Treatment for rare esophagus disease deemed breakthrough therapy by FDA: Dupixent shown to reduce esophageal inflammation

FDA Announces Guidance for Industry entitled “Eosinophilic Esophagitis: Developing Drugs for Treatment.”
This guidance is intended to describe the Agency's current thinking and recommended approach for the development of drugs and therapeutic biologics for the treatment of patients with eosinophilic esophagitis.

What it's like to get Palforzia, the first drug to treat peanut allergies in children

August 

How to Read a Food Label

July

Eosinophil responses during COVID-19 infections and coronavirus vaccinations

2020 Virtual Lab Day with the Rothenberg CURED Lab

July

Eosinophil responses during COVID-19 infections and coronavirus vaccinations

May

FDA-Approved Drug Reverses Inflammation in Animal Model of Eosinophilic Esophagitis

Progress Update for Eosinophilic Disorder Research

EGIDExpress Tool Helps Accelerate EoE Research

EOS Network - Your Questions Answered by EOS Network Professionals

Unlocking the Secrets of Eosinophilic Esophagitis: A New Children’s Book

A preliminary report (not peer-reviewed) - Alpha I Antitrypsin is an Inhibitor of the SARS-CoV2-Priming Protease TMPRSS2

The ABCs of EGIDs - online web-based education module

SECURE-EoE/EGID - Coronavirus and EoE/EGID Reporting Database

Research survey for rare disease patients and their families about impacts of COVID-19

February 

RDCRN Spotlight: Patients Power Research in Eosinophilic Gastrointestinal Disorders

Cincinnati Children's Patient Story: Nebraska Family Finds Answers & Food Options for Kids with EoE

EOS Network Website is Live!

Cincinnati Children's Patient Story: Three Matching Shirts, Three Matching Diagnoses

RDCRN Spotlight: NIH's Rare Diseases Clinical Research Network Launches New Logo

January

Research Horizons: New Tests May Help Diagnose Rare Subset of Eosinophilic Disorders

Marc E. Rothenberg was pleased to assist NORD this year in preparation of the Eosinophilic Esophagitis report for the Rare Disease Database!

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Dr. Rothenberg on Eosinophilic Disorders

Research Science Blog

Learn more about research efforts on eosinophilic conditions. The Research Horizons blog provides news and insights about the latest discoveries and innovations developed by the scientists of Cincinnati Children’s.

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