The Cincinnati Center for Eosinophilic Disorders (CCED) at Cincinnati Children's offers links to radio shows and other recent news coverage on eosinophilic disorders.
Get updated information about the novel coronavirus (COVID-19) and how it affects patients with eosinophilic conditions. Read more.
Rare Disease Day: an Opportunity to Learn More
Eliminating Just One Food Trigger Can Improve Life for People With EoE
Bringing Dietary Therapy for Eosinophilic Oesophagitis Under Scientific Scrutiny
Milk Elimination Diet Shows Promise as First-Line Therapy for Eosinophilic Esophagitis
CEGIR’s Marc Rothenberg Receives AAAAI 2023 Distinguished Scientist Award
2022 Research Highlight Videos: Division of Allergy and Immunology at Cincinnati Children's
Characterizing Eosinophilic Duodenitis
Clinical Trial Research Participation: a few words from Marc Rothenberg, MD, PhD
Biological Agent Successfully Treats Eosinophilic Esophagitis
Dupilumab improves eosinophilic esophagitis outcomes through 52 weeks
Tetsuo Shoda, MD, PhD Receives Trustee Award for his outstanding proposal entitled “Role of RhoA GTPase Pathway in Eosinophilic Esophagitis”.
Eosinophilic Gastrointestinal Disorders (EGID): Clinical Trial Update In View of Recent 2022 Data
Update on the MESSINA Phase III trial for Fasenra in eosinophilic esophagitis
Cincinnati Children's Hospital's Rothenberg named to National Academy of Medicine
Marc Rothenberg, MD, PhD Elected to National Academy of Medicine
Food Allergies Oral Immunotherapy Treatment Teal Pumpkin Campaign and More
2023 AAAAI Honorary Award Recipient of Distinguished Scientist Award: Marc Rothenberg, MD, PhD
First FDA-Approved Treatment for Eosinophilic Esophagitis Has Roots in NIAID-Funded Research
Marc Rothenberg, MD - Stephen I. Wasserman Lecture: Journey to the First FDA-Approved Drug
Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's
Vitamin D Supplementation Alleviates IL-13–Induced Esophageal Inflammation
Patients with eosinophilic esophagitis symptoms may benefit from gastric emptying studies
Marc Rothenberg selected as the 2023 recipient of the AAAAI Distinguished Scientist Award
New Treatment Gives Hope to Those with Eosinophilic Esophagitis
Journal Devotes Cover to Eosinophilic Esophagitis Research
CEGIR: Online Communities Illuminate Needs and Goals of Patients with Eosinophilic Esophagitis
Development of Outcome Metrics Leads to First FDA-Approved Treatment for Eosinophilic Esophagitis
Young and Healthy Podcast: 2022 Formula Shortage: Update for Families
Why Your Child Most Likely Does Not Have A Penicillin Allergy
NORD Applauds House Passage of H.R. 7667, the Food and Drug Amendments of 2022
FDA Approves Dupilumab for Children With Eczema Aged 6 Months to 5 Years
Q&A: Dupilumab Approved for EoE, Plus Hope for More Therapies
Q&A: FDA approval of dupilumab for eosinophilic esophagitis a ‘victory for rare diseases’
FDA Approval of Dupilumab Celebration at Cincinnati Children's
First Treatment for Eosinophilic Esophagitis Wins FDA Approval
FDA Approves First Treatment for Eosinophilic Esophagitis, a Chronic Immune Disorder
One Family’s Story about Penicillin Allergy Testing
Scientists Making Progress Against a Severe Form of Food Allergy
What to Expect from Your Nasal Endoscopy Video
Highlights of Eosinophilic Disease-Related Research (May 2021-2022)
Message on National Eosinophilic Awareness Week: CEGIR Administrative Director
Message on National Eosinophilic Awareness Week: CEGIR Principal Investigator
2022 Scholar Day Presentation by Marc Rothenberg, MD, PhD
Eosinophilic Esophagitis (NORD) Video
Cures Within Reach seeks clinical trials in health disparities or led by underserved researchers
Young and Healthy Podcast: Plant-based Milk Alternatives and Kids
New Federal Spending Bill Also Helps Food Allergic School Children
Earlier and Longer Pollen Seasons Due to Climate Change Expected to Impact Allergic Diseases
Climate Change Cited as Cause of Recent Increases in Asthma Allergy Prevalence
Building a Community to Change the Outcome Together Through Research
World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update – I – Plan and definitions
Since the World Allergy Organization (WAO) Diagnosis and Rationale against Cow's Milk Allergy (DRACMA) Guidelines were published 10 years ago, new evidence has accumulated about the diagnosis, therapy, and specific immunotherapy for cow's milk allergy (CMA). For this reason, WAO has felt the need to update the guidelines. Thank you to our local colleague, Amal H. Assa'ad, MD, for her dedicated work as part of the WAO DRACMA guideline group!
Community Access Funding to Focus on Increasing Diverse Engagement in Food Allergy Research
Molecular Analysis Suggests Eosinophilic Colitis is a Unique Disease
Cincinnati Magazine Top Doctors of 2022
We are so proud of our CCED physicians. Congratulations to Drs. Marc Rothenberg (Allergy/Immunology), Vincent Mukkada (Gastroenterology), and Philip Putnam (Gastroenterology) for being recognized as Top Doctors 2022 by Cincinnati Magazine.Allergic to Penicillin? Don't Make Rash Judgments
Preparing for Progress on Eosinophilic Gastrointestinal Diseases Beyond Eosinophilic Esophagitis
Remote immune processes revealed by immune-derived circulating cell-free DNA
Marc Rothenberg, MD, PhD and his team are collaborating with Israeli scientists to develop non-invasive biomarkers for eosinophilic esophagitis (EoE); in this publication, they describe recent findings in their pursuit to develop an EoE blood test.Two Genes Associated with Familial EoE
2021 STAT Wunderkind Award to Tetsuo Shoda
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Video
Artificial Intelligence Holds the Key to Diagnosing Rare Esophageal Food Allergy Disease
“It is exciting to see this continual positive data, especially knowing that the foundation for this therapy was derived from our long term research focus deciphering the role of type 2 immunity (IL-13) in Eosinophilic Esophagitis and other related diseases." ~Marc Rothenberg, MD, PhD
Cincinnati Children’s Launching Collaboration with Technion-Israel Institute of Technology
Neonatal Antibiotics Disrupt Esophageal Microbiota, May Increase Risk of EoE
Groundbreaking partnership combines Israeli technological prowess with pediatric medicine
Discovery of Rapid-Response Signaling Platform Suggests New Path for Blocking Allergic Inflammation
Recognized as an Expertscape World Expert in Granulocytes
Expertscape's PubMed-based algorithms placed Marc Rothenberg, MD, PhD in the top 0.1% of scholars writing about Granulocytes over the past 10 years, a level that Expertscape labels as "World Expert."
Melanie Uses Pageant Platform to Share Her Story and Build Eosinophilic Esophagitis Awareness
Summer Undergraduate Research Fellowship Awardee
Congratulations to Andrea for winning 2nd place for her Summer Undergraduate Research Fellowship (SURF) presentation! This presentation was based on the research that Andrea conducted in the Rothenberg CURED Lab through the SURF Medical Exploration program. Under the mentorship of Julia Dunn, PhD and Marc Rothenberg, MD, PhD, Andrea investigated gene expression patterns of eosinophils in patients with eosinophilic esophagitis.
NIH LRP Awardees
Congratulations to Assistant Professor Ashley L. Devonshire, MD, MPH and third-year clinical fellow Simin Zhang, MD, for being recognized for their excellence with awards from a Loan Repayment Program (LRP) of the National Institutes of Health! The NIH LRPs are a set of programs established by Congress and designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers. The escalating costs of advanced education and training in medicine and clinical specialties are forcing some scientists to abandon their research careers for higher-paying private industry or private practice careers. The LRPs counteract that financial pressure by repaying up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research and are highly competitive. Drs. Devonshire and Zhang continue the strong showing of the Division of Allergy and Immunology in having NIH LRP recipients, including prior NIH LRP awards to Drs. Michael G. Sherenian, MD, MS, Steve P. Proper, DO, PhD, and Joseph Sherrill, PhD. Since tomorrow's medical breakthroughs will be made by investigators starting in their research careers today, the LRPs represent an important investment by NIH in the future of health discovery and the wellbeing of the Nation and represent recognition of an investigator's potential. Dr. Devonshire is currently researching food allergy and food allergy risk in infants. Dr. Zhang is currently researching mast cell involvement and functions in eosinophilic esophagitis under the mentorship of Marc Rothenberg, MD, PhD and J. Pablo Abonia, MD.
Irritable Bowel Syndrome and the Food Allergy Connection
“Common gastrointestinal ailments, such as irritable bowel syndrome (IBS) and functional abdominal pain, may instead be food-induced allergic disorders,” says our Cincinnati Children's Center for Pediatric Genomics awardee Marc Rothenberg, MD, PhD in the NY Times.
Less Restrictive Diet for Adult EoE with Milk Trigger: Some Adults with EoE Allergy Can Just Cut Milk, Instead of 6 Foods
Care Providers Read Patient Comments from Experience Surveys: Vincent Mukkada
At Cincinnati Children's, our caregivers go above and beyond each day to give patients the best experience possible. Hear how they, including Vincent Mukkada, MD (Gastroenterology), react to meaningful words straight from their patient families.
April 1
Congratulations to the two Cincinnati Children's and University of Cincinnati Allergy / Immunology fellows for being recognized with first and second place in clinical research at the 10th Annual Department of Internal Medicine Research Symposium. Simin Zhang, MD was awarded 1st for her project “Clinical Significance of Mast Cell Density in GI Biopsies in Patients Presenting for Evaluation of GI Mast Cell Disorders”, and David Adams, PhD was awarded 2nd place for his project: "Multifactorial Regulation of Axl Expression".
March
Who We Are: Rare Diseases Clinical Research Network Video
February 22
Cincinnati Children’s Team and Faculty Awards
Allergy Nursing Team recognized as the “2020 Top Performing Small Division for Outstanding Nursing Patient Family Experience (PFE)”! This honor was awarded based on a review of the annual experience survey scores and positive comments, which highlight the exceptional feedback the team routinely receives from the patients and families. The team was recognized in a virtual awards ceremony held on Monday, February 22nd. Thank you for all you do, for making a difference in the lives of so many families and for promoting a positive experience at Cincinnati Children’s!
Vincent Mukkada, MD received the “2020 Top Pediatric Provider Award” at Cincinnati Children’s! This is an amazing, well-deserved accomplishment, reflecting not only his outstanding clinical care, but also a great team at large with the Division of Gastroenterology, Hepatology and Nutrition and the Cincinnati Center for Eosinophilic Disorders.
Kimberly Risma, MD, PhD received the “2020 Clinical Care Achievement Award”! Dr. Risma is an extraordinary clinician whose innovation has led to the creation of the Drug Allergy Program launched in 2019. She is also having a leading impact in promoting the next generation of physicians in the allergy and immunology field. This award is most deserving and demonstrates appreciation for her immense dedication, talents and contributions.
February 11
2020 Research Highlights: Division of Allergy and Immunology
February 11
RDCRN Announces New 2021 Network Steering Committee Leadership
We are pleased to announce that Marc Rothenberg, MD, PhD has been elected as co-chair of the Rare Diseases Clinical Research Network (RDCRN, www.rarediseasesnetwork.org) Steering Committee. Dr. Rothenberg will join Dr. Jennifer Puck and Dr. Andrea Gropman in leading the RDCRN Steering Committee.
January 21
Cincinnati Children’s to House Food Allergy Biobank and Biomarker Discovery Center
January 21
FARE Announces Key Partnerships in Crusade to Advance Food Allergy Research
January 13
EoE Research Selected as ‘Editor’s Choice’ in JACI
January 6
How Experts at Cincinnati Children's Hospital Medical Center are Combatting Allergic Reactions
U.S. Senate Passes FASTER Act, Brings Sesame Labeling One Step Closer for Food Allergy Community
Transferring Allergies in the Womb
Dr. Rothenberg shares his perspective on a recent article about how maternal mast cells are involved in allergy development in this invited Science Perspective.
Asian Children With Food Allergies More Likely to Experience Quality of Life Challenges
MSSRP Poster Award Winners
Susie Min and Rahul Sandella participated in the 10th Annual Research and Service Symposium at UC on Friday, November 6th. We appreciate UC providing a virtual forum for the MSSRP Program poster judging this year. Susie Min won second place for "Molecular Diagnosis of Eosinophilic Esophagitis from a Single Esophageal Biopsy" with the mentorship of Ting Wen, PhD and Marc Rothenberg, MD, PhD. She will represent us at the annual National Student Research Forum (NSRF) in Galveston, TX (April, 2021). Rahul Sandella won third place for "The Effects of Adiposity on Disease and Symptom Severity in Eosinophilic Esophagitis" with the mentorship of Vincent A. Mukkada, MD and Kara Kliewer, RD, PhD.
Grateful Patient with Eosinophilia Thanks Cincinnati Children’s For Improved Life
Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis
Patients with eosinophilic gastritis (EG) have limited therapeutic options. The Cincinnati Center for Eosinophilic Disorders is proud to have been an integral part of an important trial, now published in the New England Journal of Medicine, demonstrating that lirentelimab significantly and safely improves symptoms in subjects with EG while eradicating eosinophils. We are hopeful that the Phase 3 trial, which is now enrolling participants, will ultimately confirm these findings so that there are more clinically approved therapeutic options for individuals with this rare disorder.
Roots of New Drug for HES Trace Back to Cincinnati Children’s
Cincinnati Children's helps pave way for newly approved use of drug
FDA Announces Guidance for Industry entitled “Eosinophilic Esophagitis: Developing Drugs for Treatment.”
This guidance is intended to describe the Agency's current thinking and recommended approach for the development of drugs and therapeutic biologics for the treatment of patients with eosinophilic esophagitis.
What it's like to get Palforzia, the first drug to treat peanut allergies in children
Eosinophil responses during COVID-19 infections and coronavirus vaccinations
2020 Virtual Lab Day with the Rothenberg CURED Lab
Eosinophil responses during COVID-19 infections and coronavirus vaccinations
FDA-Approved Drug Reverses Inflammation in Animal Model of Eosinophilic Esophagitis
Progress Update for Eosinophilic Disorder Research
EGIDExpress Tool Helps Accelerate EoE Research
EOS Network - Your Questions Answered by EOS Network Professionals
Unlocking the Secrets of Eosinophilic Esophagitis: A New Children’s Book
A preliminary report (not peer-reviewed) - Alpha I Antitrypsin is an Inhibitor of the SARS-CoV2-Priming Protease TMPRSS2
The ABCs of EGIDs - online web-based education module
SECURE-EoE/EGID - Coronavirus and EoE/EGID Reporting Database
Research survey for rare disease patients and their families about impacts of COVID-19
RDCRN Spotlight: Patients Power Research in Eosinophilic Gastrointestinal Disorders
Cincinnati Children's Patient Story: Nebraska Family Finds Answers & Food Options for Kids with EoE
Cincinnati Children's Patient Story: Three Matching Shirts, Three Matching Diagnoses
RDCRN Spotlight: https://www.rarediseasesnetwork.org/news/rdcrn/2020-02/nihs-rare-diseases-clinical-research-network-launches-new-logo
Research Horizons: New Tests May Help Diagnose Rare Subset of Eosinophilic Disorders
Marc E. Rothenberg was pleased to assist NORD this year in preparation of the Eosinophilic Esophagitis report for the Rare Disease Database!
Listen to Marc E. Rothenberg, MD, PhD, speak about the importance of the CURED Foundation as heard on ReachMD XM 233.
Learn more about research efforts on eosinophilic conditions. The Research Horizons blog provides news and insights about the latest discoveries and innovations developed by the scientists of Cincinnati Children’s.
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