Remote immune processes revealed by immune-derived circulating cell-free DNA
Marc Rothenberg, MD, PhD
and his team are collaborating with Israeli scientists to develop non-invasive biomarkers for eosinophilic esophagitis (EoE); in this publication, they describe recent findings in their pursuit to develop an EoE blood test.
Two Genes Associated with Familial EoE
2021 STAT Wunderkind Award to Tetsuo Shoda
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Video
Artificial Intelligence Holds the Key to Diagnosing Rare Esophageal Food Allergy Disease
Second DUPIXENT® (Dupilumab) Phase 3 Eosinophilic Esophagitis Trial To Demonstrate Significant Disease Improvements, Underscoring Role of Type 2 Inflammation in This Complex Disease
“It is exciting to see this continual positive data, especially knowing that the foundation for this therapy was derived from our long term research focus deciphering the role of type 2 immunity (IL-13) in Eosinophilic Esophagitis and other related diseases." ~Marc Rothenberg, MD, PhD
Cincinnati Children’s Launching Collaboration with Technion-Israel Institute of Technology
FDA expands approval of Dupixent® (dupilumab) to include children aged 6 to 11 years with moderate-to-severe asthma
Neonatal Antibiotics Disrupt Esophageal Microbiota, May Increase Risk of EoE
Groundbreaking partnership combines Israeli technological prowess with pediatric medicine
Discovery of Rapid-Response Signaling Platform Suggests New Path for Blocking Allergic Inflammation
Recognized as an Expertscape World Expert in Granulocytes
Expertscape's PubMed-based algorithms placed Marc Rothenberg, MD, PhD in the top 0.1% of scholars writing about Granulocytes over the past 10 years, a level that Expertscape labels as "World Expert."
Melanie Uses Pageant Platform to Share Her Story and Build Eosinophilic Esophagitis Awareness
Bridge to Next-Gen Medicine
Summer Undergraduate Research Fellowship Awardee
Congratulations to Andrea for winning 2nd place for her Summer Undergraduate Research Fellowship (SURF) presentation! This presentation was based on the research that Andrea conducted in the Rothenberg CURED Lab through the SURF Medical Exploration program. Under the mentorship of Julia Dunn, PhD and Marc Rothenberg, MD, PhD, Andrea investigated gene expression patterns of eosinophils in patients with eosinophilic esophagitis.
NIH LRP Awardees
Congratulations to Assistant Professor Ashley L. Devonshire, MD, MPH and third-year clinical fellow Simin Zhang, MD, for being recognized for their excellence with awards from a Loan Repayment Program (LRP) of the National Institutes of Health!
The NIH LRPs are a set of programs established by Congress and designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers. The escalating costs of advanced education and training in medicine and clinical specialties are forcing some scientists to abandon their research careers for higher-paying private industry or private practice careers. The LRPs counteract that financial pressure by repaying up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research and are highly competitive.
Drs. Devonshire and Zhang continue the strong showing of the Division of Allergy and Immunology in having NIH LRP recipients, including prior NIH LRP awards to Drs. Michael G. Sherenian, MD, MS, Steve P. Proper, DO, PhD, and Joseph Sherrill, PhD.
Since tomorrow's medical breakthroughs will be made by investigators starting in their research careers today, the LRPs represent an important investment by NIH in the future of health discovery and the wellbeing of the Nation and represent recognition of an investigator's potential. Dr. Devonshire is currently researching food allergy and food allergy risk in infants. Dr. Zhang is currently researching mast cell involvement and functions in eosinophilic esophagitis under the mentorship of Marc Rothenberg, MD, PhD and J. Pablo Abonia, MD.
Irritable Bowel Syndrome and the Food Allergy Connection
“Common gastrointestinal ailments, such as irritable bowel syndrome (IBS) and functional abdominal pain, may instead be food-induced allergic disorders,” says our Cincinnati Children's Center for Pediatric Genomics awardee Marc Rothenberg, MD, PhD in the NY Times.
Less Restrictive Diet for Adult EoE with Milk Trigger: Some Adults with EoE Allergy Can Just Cut Milk, Instead of 6 Foods
Care Providers Read Patient Comments from Experience Surveys: Vincent Mukkada
At Cincinnati Children's, our caregivers go above and beyond each day to give patients the best experience possible. Hear how they, including Vincent Mukkada, MD (Gastroenterology), react to meaningful words straight from their patient families.
EoE: the Food Allergy Disease
Eosinophilic Asthma: What Doctors Need You to Know
Artificial Intelligence in Allergy/Immunology Transformative machine learning in diagnosing eosinophilic esophagitis (EoE)
Man Undergoing Treatment of Rare Genetic Condition Graduates College 2,500 Miles Away From Home
Decoding the Mysteries of Postural Orthostatic Tachycardia Syndrome
This is encouraging news for all of our patients and families effected by the combination of postural orthostatic tachycardia syndrome (POTS) and eosinophilic gastrointestinal disorders (EGIDs).
Congratulations to the two Cincinnati Children's and University of Cincinnati Allergy / Immunology fellows for being recognized with first and second place in clinical research at the 10th Annual Department of Internal Medicine Research Symposium. Simin Zhang, MD was awarded 1st for her project “Clinical Significance of Mast Cell Density in GI Biopsies in Patients Presenting for Evaluation of GI Mast Cell Disorders”, and David Adams, PhD was awarded 2nd place for his project: "Multifactorial Regulation of Axl Expression".
Who We Are: Rare Diseases Clinical Research Network Video
Cincinnati Children’s Team and Faculty Awards
Allergy Nursing Team recognized as the “2020 Top Performing Small Division for Outstanding Nursing Patient Family Experience (PFE)”! This honor was awarded based on a review of the annual experience survey scores and positive comments, which highlight the exceptional feedback the team routinely receives from the patients and families. The team was recognized in a virtual awards ceremony held on Monday, February 22nd. Thank you for all you do, for making a difference in the lives of so many families and for promoting a positive experience at Cincinnati Children’s!
Vincent Mukkada, MD received the “2020 Top Pediatric Provider Award” at Cincinnati Children’s! This is an amazing, well-deserved accomplishment, reflecting not only his outstanding clinical care, but also a great team at large with the Division of Gastroenterology, Hepatology and Nutrition and the Cincinnati Center for Eosinophilic Disorders.
Kimberly Risma, MD, PhD received the “2020 Clinical Care Achievement Award”! Dr. Risma is an extraordinary clinician whose innovation has led to the creation of the Drug Allergy Program launched in 2019. She is also having a leading impact in promoting the next generation of physicians in the allergy and immunology field. This award is most deserving and demonstrates appreciation for her immense dedication, talents and contributions.
2020 Research Highlights: Division of Allergy and Immunology
RDCRN Announces New 2021 Network Steering Committee Leadership
We are pleased to announce that Marc Rothenberg, MD, PhD has been elected as co-chair of the Rare Diseases Clinical Research Network (RDCRN, www.rarediseasesnetwork.org) Steering Committee. Dr. Rothenberg will join Dr. Jennifer Puck and Dr. Andrea Gropman in leading the RDCRN Steering Committee.
Cincinnati Children’s to House Food Allergy Biobank and Biomarker Discovery Center
FARE Announces Key Partnerships in Crusade to Advance Food Allergy Research
Scientist Spotlight: Marc Rothenberg Leads Eosinophilic Collaboration and Research to New Discoveries
EoE Research Selected as ‘Editor’s Choice’ in JACI
How Experts at Cincinnati Children's Hospital Medical Center are Combatting Allergic Reactions