What is the Treatment for Eosinophilic Disorders?

Eosinophilic disorders are often misdiagnosed and misunderstood because the symptoms are shared with a number of conditions.

Though these conditions are lifelong, the disease activity and symptoms of these disorders can be effectively managed in many cases by the dedicated and consistent care of families and healthcare professionals, such as the multidisciplinary team of specialists at the Cincinnati Center for Eosinophilic Disorders (CCED), who are researching improved treatments and a cure.

At present, the two main treatments for eosinophilic disorders, such as eosinophilic gastrointestinal disorders (EGIDs) and hypereosinophilic syndrome (HES) are medications and dietary therapy. Medications and dietary therapy can be used singly or together. Which treatments are used depends on the eosinophilic condition.

What is the treatment for eosinophilic esophagitis (EoE)?
EoE responds well to topical steroids, emerging biologic therapy, and/or dietary therapy. Esophageal dilation is sometimes used to relieve dysphagia, a common symptom of EoE.

What is the treatment for eosinophilic gastritis (EoG)?
EoG responds well to systemic steroids, but how EoG responds to dietary therapy is not yet known and understudied due to low EoG prevalence.

What is the treatment for eosinophilic enteritis (EoN)?
EoN responds well to systemic steroids, but how EoN responds to dietary therapy is not yet known and understudied due to low EoN prevalence.

What is the treatment for eosinophilic colitis (EoC)?
EoC responds well to systemic steroids, but how EoC responds to dietary therapy is not yet known and understudied due to low EoC prevalence.

What is the treatment for hypereosinophilic syndrome (HES)?
HES responds well to systemic steroids. Dietary therapy is not a treatment option for HES.

FDA Approval of Dupilumab (Dupixent) for EoE

The FDA approved Dupilumab (Dupixent) for eosinophilic esophagitis (EoE) on May 20, 2022. Read a message from our providers.