Antioxidant found to reduce liver injury and increase survival in mouse models of Biliary Atresia
Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue.
Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory.
Early intervention with treatments like gastric bypass surgery before adolescents become adults controls the diabetes and possibly throws it into remission.
Cincinnati Children’s scientists trace an inflammatory cascade to a surprising origin—the lining of blood vessels in the decidua.
Cincinnati Children’s Hospital Medical Center will use a $30 million federal grant o accelerate the chase for one of medicine’s most elusive goals: a universal influenza vaccine.
New findings published in Science Signaling suggest that targeting mechanical signals between cells may become a fresh approach to fighting cancer.
Spliceosome misconnects generate mutant gene/protein that fuel cancerous leukemia cells.
Study uses cell-by-cell analyses to look for new glioblastoma therapies.
The study, led by Ting Wen, MD, PhD, and Marc Rothenberg, MD, PhD, was published in the Journal of Clinical Investigation.
The findings in Nature Cell Biology suggest it may be possible to use light therapy to help premature babies whose eyes are still developing avoid vision problems.
Drawing on recent advances in microfluidics, imaging, computational sciences, and other technologies, a Pediatric Cell Atlas would offer an unprecedented window into the biology of human growth and development.
A new study published in The Journal of Pediatrics shows that more than a third of middle school kids have high cholesterol or abnormal levels of blood sugar.
A new mathematical method, published in Genome Research, makes it easier to identify networks of transcription factors (TFs) that control gene expression in specific cell types.
Publishing their findings in Nature Structural & Molecular Biology, Cincinnati Children’s scientists say nature prepares the 3D arrangement of DNA before packing it into sperm.
In an effort to stop Ebola from spreading, the clinical trial will test two experimental vaccines together for their safety and ability to produce an immune response in healthy adults.
$222.5M in Funding Leads to Dozens of Discoveries, Including Genes Linked to Preterm Birth, Mono Virus May Contribute to Multiple Diseases, and Community-Wide Improvements in Asthma Outcomes
To help babies have a better developmental outcome, Cincinnati Children’s is launching the NICU Bookwork Program to help parents bond with their newborns through books.
Cincinnati Children’s researcher hope the Pediatric Asthma Risk Score (PARS) will become the most common tool used by medical practitioners to predict asthma.
After over a decade of preclinical research and development, a new gene therapy treatment for sickle cell anemia (SCA) is reversing disease symptoms in two adults. Punam Malik, MD, is the principal investigator.
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