The PSCF has ESCRO approval for the majority of common hESC procedures. During preliminary discussions, the facility director will review an investigator's planned experiments and ascertain whether additional ESCRO approval is required. If not, we encourage investigators to perform their approved experiments in the facility using our ESCRO approval. This is ideal for performing proof of principle studies. However, if an investigator proposes experimental approaches not covered in our approvals, or wishes to use cells not supplied by the facility, he/she must obtain their own ESCRO approval, as well as appropriate IBC and IACUC permissions before beginning hESC research. Regardless of the level of ESCRO approval required the PSCF will assist to facilitate the application procedure. Contact the Cincinnati Children's ESCRO committee at
ESCRO@cchmc.org.