As a pediatric surgeon scientist, Dr. Helmrath has established a large multidisciplinary team dedicated to clinical, translational, and basic science research focused on human diseases. Clinically, he is dedicated to patients with intestinal diseases and obesity. In his laboratory he focuses on characterizing intestinal stem cells during intestinal adaptation and developing intestinal regenerative strategies. He has expertise in the generation of stem cells and the development of organoids. His strong basic science research background further allows him to translate human GI conditions to the laboratory to develop highly innovative approaches to treat intestinal diseases.