A photo of Michael Helmrath.

Surgical Director, Intestinal Rehabilitation Program

Director of Surgical Research
Associate Director of Clinical Translation, CuSTOM
Director, Center for Bariatric Research and Innovation
Pediatric Surgeon

Professor, UC Department of Surgery


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Board Certified

My Biography & Research


As a pediatric surgeon scientist, Dr. Helmrath has established a large multidisciplinary team dedicated to clinical, translational, and basic science research focused on human diseases. Clinically, he is dedicated to patients with intestinal diseases and obesity. In his laboratory he focuses on characterizing intestinal stem cells during intestinal adaptation and developing intestinal regenerative strategies. By combining his current roles as director of Surgical Research, director for the Center for Bariatric Research and Innovation, surgical director of the Intestinal Rehabilitation Program, and associate director of Clinical Translation for CuSTOM, his strong basic science research background further allows him to translate human GI conditions to the laboratory to develop highly innovative approaches to treat intestinal diseases.

Academic Affiliation

Professor, UC Department of Surgery


Colorectal Center, Surgery - General and Thoracic, General and Thoracic Surgery, Cincinnati Childrens Intestinal Care Center CCICC, Surgical Weight Loss Program for Teens, Best Doctors 2017-18

My Locations

My Education

BA: Miami University, Oxford, OH, 1987.

MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.

MS: University of Cincinnati College of Medicine, Cincinnati, OH, 1989.

Certification: Board-certified General Surgery; board-certified, Pediatric Surgery.

My Publications

Poling HM, Wu D, Brown N, Baker M, Hausfeld TA, Huynh N, Chaffron S, Dunn JCY, Hogan SP, Wells JM, Helmrath MA, Mahe MM. Mechanically induced development and maturation of human intestinal organoids in vivo. Nat Biomed Eng. 2018 Jun;2(6):429-442.

Takebe T, Wells JM, Helmrath MA, Zorn AM. Organoid Center Strategies for Accelerating Clinical Translation. Cell Stem Cell. 2018 Jun 1;22(6):806-809.

Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nat Med. 2017 Jan;23(1):49-59.

Inge TH, Courcoulas AP, Jenkins TM, Michalsky MP, Helmrath MA, Brandt ML, Harmon CM, Zeller MH, Chen MK, Xanthakos SA, Horlick M, Buncher CR; Teen-LABS Consortium. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. N Engl J Med. 2016 Jan 14;374(2):113-23.