Michael A. Helmrath, MD

Surgical Director, Intestinal Rehabilitation Program

Director of Surgical Research
Associate Director of Clinical Translation, CuSTOM
Director, Center for Bariatric Research and Innovation
Pediatric Surgeon

Academic Affiliations

Professor, UC Department of Surgery

Phone 513-636-4371

Email michael.helmrath@cchmc.org

Research InterestsHide

Visit the Helmrath Lab.

BiographyHide

As a pediatric surgeon scientist, Dr. Helmrath has established a large multidisciplinary team dedicated to clinical, translational, and basic science research focused on human diseases. Clinically, he is dedicated to patients with intestinal diseases and obesity. In his laboratory he focuses on characterizing intestinal stem cells during intestinal adaptation and developing intestinal regenerative strategies. By combining his current roles as surgical director of research, director for the Center for Bariatric Research and Innovation, surgical director of the Intestinal Rehabilitation Program, and associate director of Clinical Translation for CuSTOM, his strong basic science research background further allows him to translate human GI conditions to the laboratory to develop highly innovative approaches to treat intestinal diseases.

Education and TrainingHide

BA: Miami University, Oxford, OH, 1987.

MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.

MS: University of Cincinnati College of Medicine, Cincinnati, OH, 1989.

Certification: Board-certified General Surgery; board-certified, Pediatric Surgery.

PublicationsHide

View PubMed Publications

Michalsky MP, Inge TH, Teich S, Eneli I, Miller R, Brandt ML, Helmrath M, Harmon CM, Zeller MH, Jenkins TM, Courcoulas A, Buncher RC; Teen-LABS Consortium. Adolescent bariatric surgery program characteristics: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience. Semin Pediatr Surg. 2014 Feb;23(1):5-10.

Inge TH, Zeller MH, Jenkins TM, Helmrath M, Brandt ML, Michalsky MP, Harmon CM, Courcoulas A, Horlick M, Xanthakos SA, Dolan L, Mitsnefes M, Barnett SJ, Buncher R; Teen-LABS Consortium. Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. JAMA Pediatr. 2014 Jan;168(1):47-53.

Ubesie AC, Kocoshis SA, Mezoff AG, Henderson CJ, Helmrath MA, Cole CR. Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition. J Pediatr. 2013 Dec;163(6):1692-6.

Eradi B, Hamrick M, Bischoff A, Frischer JS, Helmrath M, Hall J, Pena A, Levitt MA. The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence. J Pediatr Surg. 2013 Nov; 48(11):2296-300.

Fuller MK, Faulk DM, Sundaram N, Mahe MM, Stout KM, von Furstenberg RJ, Smith BJ, McNaughton KK, Shroyer NF, Helmrath MA, Henning SJ. Intestinal stem cells remain viable after prolonged tissue storage. Cell Tissue Res. 2013 Nov;354(2):441-50.

Devine AA, Gonzalez A, Speck KE, Knight R, Helmrath M, Lund PK, Azcarate-Peril MA. Impact of ileocecal resection and concomitant antibiotics on the microbiome of the murine jejunum and colon. PLoS One. 2013; 8(8):e73140.

Fuller MK, Faulk DM, Sundaram N, Shroyer NF, Henning SJ, Helmrath MA. Intestinal crypts reproducibly expand in culture. J Surg Res. 2012 Nov;178(1):48-54.

Stelzner M, Helmrath M, Dunn JC, Henning SJ, Houchen CW, Kuo C, Lynch J, Li L, Magness ST, Martin MG, Wong MH, Yu J; NIH Intestinal Stem Cell Consortium. A nomenclature for intestinal in vitro cultures. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1359-63.

Van Landeghem L, Blue RE, Dehmer JJ, Henning SJ, Helmrath MA, Lund PK. Localized intestinal radiation and liquid diet enhance survival and permit evaluation of long-term intestinal responses to high dose radiation in mice. PLoS One. 2012;7(12):e51310.

GrantsHide

Adolescent Bariatrics: Assessing Health Benefits & Risk. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. Nov 2011–Oct 2016. U01 DK072493.

Human Endocrine Cell Development. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. Apr 2012–Mar 2017. R01 DK092456.

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Michael A. Helmrath, MD

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