Publications

Borcherding, DC; Siefert, ME; Lin, S; Brewington, J; Sadek, H; Clancy, JP; Plafker, SM; Ziady, AG. Clinically-approved CFTR modulators rescue Nrf2 dysfunction in cystic fibrosis airway epithelia. The Journal of Clinical Investigation. 2019; 129:3448-3463.

Cheng, Y; Doane, TL; Chuang, C; Ziady, A; Burda, C. Near infrared light-triggered drug generation and release from gold nanoparticle carriers for photodynamic therapy. Small. 2014; 10:1799-1804.

Ziady, AG; Sokolow, A; Shank, S; Corey, D; Myers, R; Plafker, S; Kelley, TJ. Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2012; 302:L1221-L1231.

Drumm, ML; Ziady, AG; Davis, PB. Genetic variation and clinical heterogeneity in cystic fibrosis. Editor, Abbas AK; Galli SJ; Howley PM. Annual Review of Pathology: Mechanisms of Disease. 2012; 7:267-282.

Yurek, DM; Fletcher, AM; McShane, M; Kowalczyk, TH; Padegimas, L; Weatherspoon, MR; Kaytor, MD; Cooper, MJ; Ziady, AG. DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging. Molecular imaging : official journal of the Society for Molecular Imaging. 2011; 10:327-339.

Chen, X; Shank, S; Davis, PB; Ziady, AG. Nucleolin-mediated cellular trafficking of DNA nanoparticle is lipid raft and microtubule dependent and can be modulated by glucocorticoid. Molecular Therapy. 2011; 19:93-102.

Ko, IK; Ziady, A; Lu, S; Kwon, YJ. Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier. Biomaterials. 2008; 29:3872-3881.

Konstan, MW; Davis, PB; Wagener, JS; Hilliard, KA; Stern, RC; Milgram, LJ H; Kowalczyk, TH; Hyatt, SL; Fink, TL; Gedeon, CR; Muhammad, O; Ziady, AG; Moen, RC; Cooper, MJ. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Human Gene Therapy. 2004; 15:1255-1269.

Ziady, AG; Gedeon, CR; Miller, T; Quan, W; Payne, JM; Hyatt, SL; Fink, TL; Muhammad, O; Oette, S; Kowalczyk, T; Pasumarthy, MK; Moen, RC; Cooper, MJ; Davis, PB. Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo. Molecular Therapy. 2003; 8:936-947.

Ziady, AG; Kelley, TJ; Milliken, E; Ferkol, T; Davis, PB. Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor. Molecular Therapy. 2002; 5:413-419.

Walder, TA; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Rare BK polyomavirus subtype III detected in hematopoietic cell transplant recipient. Editor, Matthijnssens J. Microbiology Resource Announcements. 2024; 13:e0067624.

Skala, E; Banerjee, R; Siefert, M; Dusa, C; Stevens, C; Hils, B; Bdaiwi, A; Hayes, D; Cleveland, Z; Ziady, A. 846 Plasma proteomics identifies changes in disease-associated pathways in subjects with CF bronchiectasis after elexacaftor/tezacaftor/ivacaftor initiation. Journal of Cystic Fibrosis. 2024; 23:s490.

Auld, SC; Sheshadri, A; Alexander-Brett, J; Aschner, Y; Barczak, AK; Basil, MC; Cohen, KA; Cruz, CD; McGroder, C; Restrepo, MI; Staitieh, BS; Stek, C; Sun, J; Evans, SE. Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society. 2024; 21:1219-1237.

Siefert, M; Rheiner, S; Ziady, A; Lin, S. 269 Modulating nucleolin trafficking can significantly enhance DNA nanoparticle-mediated gene expression in the lung. Journal of Cystic Fibrosis. 2024; 23:s143.

Chokshi, SM; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Uncommon BK polyomaviruses detected in allogeneic hematopoietic cell transplant recipients. Editor, Matthijnssens J. Microbiology Resource Announcements. 2024; 13:e0000524.

Chokshi, SM; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Uncommon BK polyomaviruses detected in allogeneic hematopoietic cell transplant recipients. Microbiology Resource Announcements. 2024; 13.

Skala, EJ; Siefert, ME; Potter, AS; Sharma, N; Hayes, D; Ziady, AG. (610) Bronchoalveolar Lavage and Plasma Proteomes Identify Features of Disease That Segregate Lung Transplant Recipients with versus without Bronchiolitis Obliterans Syndrome. The Journal of Heart and Lung Transplantation. 2024; 43:s297.

Siefert, ME; Skala, EJ; Potter, AS; Hayes, D; Ziady, A. (1358) Plasma and Bronchoalveolar Fluid Proteomes Identify Similar Pathways Associated with Allograft Dysfunction in Individual LTx Recipients with Different Underlying Conditions. The Journal of Heart and Lung Transplantation. 2024; 43:s625-s626.

Potter, A; Wikenheiser-Brokamp, K; Hildeman, D; Sharma, N; Gu, M; Patel, K; Qureshi, M; Khan, MM; Wallace, C; Ziady, A; Hayes, D. (601) Decoding T Cell Clonal Dynamics in Acute Lung Rejection. The Journal of Heart and Lung Transplantation. 2024; 43:s293.

Koo, J; Langenberg, L; Luebbering, N; Strecker, L; Abdullah, S; Carusone, E; Deavy, M; Hoerth, C; Miller, G; Turner, D; Ziady, AG; Myers, KC; Jodele, S; Davies, SM. Ceramides Are Elevated in Transplant-Associated Thrombotic Microangiopathy in Hematopoietic Stem Cell Transplant Recipients and Are a Druggable Target for Prophylaxis. Transplantation and Cellular Therapy. 2024; 30:s17-s18.

Sabulski, A; Abdullah, S; Luebbering, N; Aunins, B; Castillo, C; Lake, K; Duell, A; Strecker, L; Langenberg, L; Broomhead, W; Dandoy, CE; Laskin, BL; Jodele, S; Davies, SM. Mechanisms of endothelial injury and transplant-associated thrombotic microangiopathy in tandem autologous hematopoietic stem cell transplant for neuroblastoma. Haematologica: the hematology journal. 2023; 108:3449-3453.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Diversity After Hematopoietic Stem Cell Transplantation. The Journal of Infectious Diseases. 2023; 228:1208-1218.

Koo, J; Ziady, AG; Reynaud, D; Abdullah, S; Luebbering, N; Kahn, S; Langenberg, L; Strecker, L; Lake, K; Dandoy, CE; Siefert, ME; Skala, E; Jodele, S; Davies, SM. Increased Body Mass Index Augments Endothelial Injury and Clinical Outcomes after Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy. 2023; 29:704.e1-704.e8.

Koh, W; Zang, H; Ollberding, NJ; Ziady, A; Hayes, D. Extracorporeal membrane oxygenation bridge to pediatric lung transplantation: Modern era analysis. Pediatric Transplantation. 2023; 27:e14570.

Guzman-Gomez, A; Ahmed, HF; Dani, A; Zafar, F; Lehenbauer, DG; Potter, AS; Morales, DL S; Ziady, AG; Hayes, D. Center volume effect on acute cellular rejection and outcomes in pediatric lung transplant recipients. The Journal of Heart and Lung Transplantation. 2023; 42:1030-1039.

Wagner, ML; Ammann, A; Piraino, G; Wolfe, V; O'Connor, M; Lahni, P; Ziady, A; Zingarelli, B. PROTECTIVE EFFECTS OF HUMANIN-G IN HEMORRHAGIC SHOCK IN FEMALE MICE VIA AMPKα1-INDEPENDENT MECHANISMS. Shock. 2023; 60:64-74.

Pradhan, A; Che, L; Ustiyan, V; Reza, AA; Pek, NM; Zhang, Y; Alber, AB; Kalin, TR; Wambach, JA; Gu, M; Kotton, DN; Siefert, ME; Ziady, AG; Kalin, TV; Kalinichenko, VV. Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2023; 207:1042-1054.

Guzman-Gomez, A; Skala, E; Dani, A; Sharma, N; Ziady, A; Hayes, D. Sex and Sex Hormones Matter in Lung Transplant Outcomes. The Journal of Heart and Lung Transplantation. 2023; 42:s141.

Zhang, G; Odegard, E; Sabulski, DA; Jodele, S; Ziady, A; Seif, AE; Davies, SM; Laskin, B; Blackard, JT. 441 Evolution of BK Polyomavirus in Immunocompromised Pediatric Patients. Transplantation and Cellular Therapy. 2023; 29:s333-s334.

Sabulski, DA; Siefert, ME; Skala, E; Abdullah, S; Luebbering, N; Myers, K; Odegard, E; Blackard, JT; Seif, AE; Jodele, S; Davies, SM; Laskin, B; Ziady, A. 77 Proteomic Analyses Reveal Molecular Connections That Support the Clinical Association of Cystitis with Thrombotic Microangiopathy in Pediatric Transplant Recipients. Transplantation and Cellular Therapy. 2023; 29:s64-s65.

Hayes, D; Dani, A; Guzman-Gomez, A; Zafar, F; Morales, DL S; Ziady, AG. Changing racial and ethnic differences for lung transplantation in cystic fibrosis. Pediatric Transplantation. 2023; 27:e14404.

Odegard, E; Meeds, H; Kleiboeker, S; Ziady, A; Sabulski, DA; Jodele, S; Seif, AE; Davies, SM; Laskin, B; Blackard, JT. 429 BK Polyomavirus after Pediatric Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy. 2023; 29:s324-s325.

Koo, DJ; Reynaud, D; Ziady, A; Kahn, S; Abdullah, S; Luebbering, N; Strecker, L; Lake, KE; Giordullo, L; Ibrahimova, A; Good, S; Dandoy, DC E; Myers, K; Jodele, S; Davies, SM. 166 Reduced Sphingosine-1-Phosphate Leads to Hypoxemia and Lung Injury after Hematopoietic Stem Cell Transplant. Transplantation and Cellular Therapy. 2023; 29:s134.

Hudock, KM; Collins, MS; Imbrogno, MA; Kramer, EL; Brewington, JJ; Ziady, A; Zhang, N; Snowball, J; Xu, Y; Carey, BC; Gollomp, K; Mangalmurti, N; Trapnell, BC; Clancy, JP. Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in Immunology. 2023; 13:1023553.

Sabulski, A; Abdullah, S; Luebbering, N; Aunins, B; Castillo, C; Lake, K; Duell, A; Strecker, L; Giordullo, L; Broomhead, W; Dandoy, CE; Laskin, BL; Jodele, S; Davies, SM. Circulating endothelial cells and the study of vascular injury in children undergoing hematopoietic stem cell transplant. Haematologica: the hematology journal. 2022; 107:2950-2954.

Schwarzenberg, SJ; Palermo, JJ; Ye, W; Huang, S; Magee, JC; Alazraki, A; Freeman, AJ; Harned, R; Karmazyn, B; Karnsakul, W; Stoll, J; Towbin, AJ; Narkewicz, MR; Alonso, EM. Health-related Quality of Life in a Prospective Study of Ultrasound to Detect Cystic Fibrosis-related Liver Disease in Children. Journal of Pediatric Gastroenterology and Nutrition. 2022; 75:635-642.

Skala, E; Hayes, D; Ziady, A. 174 Identification of physiological characteristics at baseline and 1 and 6 months that segregate lung function response to ivacaftor using proteomic analysis. Journal of Cystic Fibrosis. 2022; 21:s101-s102.

Skala, E; Sharma, N; Hayes, D; Ziady, A. 143 Bronchoalveolar lavage proteome identifies pathways of disease that segregate lung transplant recipients with and without bronchiolitis obliterans syndrome. Journal of Cystic Fibrosis. 2022; 21:s84.

Siefert, M; Rheiner, S; Adams, M; Hayes, H; Lin, S; Ziady, A. 591 Modulation of the deoxyribonucleic acid nanoparticle interactome enhances cystic fibrosis transmembrane conductance regulator gene transfer in a cystic fibrosis mouse model. Journal of Cystic Fibrosis. 2022; 21:s328.

Dani, A; Zafar, F; Morales, D; Ziady, A; Hayes, D. 147 Lung transplantation waitlist disparities for children with cystic fibrosis. Journal of Cystic Fibrosis. 2022; 21:s86.

Hayes, D; Melicoff-Portillo, E; Ziady, AG. Selection of lung transplant candidates: A pediatric perspective on the International Society for Heart and Lung Transplantation consensus document. The Journal of Heart and Lung Transplantation. 2022; 41:998-999.

Hayes, D; Shukla, RK; Cheng, Y; Gecili, E; Merling, MR; Szczesniak, RD; Ziady, AG; Woods, JC; Hall-Stoodley, L; Liyanage, NP M; Robinson, RT. Tissue-localized immune responses in people with cystic fibrosis and respiratory nontuberculous mycobacteria infection. JCI insight. 2022; 7:e157865.

Gecili, E; Sivaganesan, S; Asar, O; Clancy, JP; Ziady, A; Szczesniak, RD. Bayesian regularization for a nonstationary Gaussian linear mixed effects model. Statistics in Medicine. 2022; 41:681-697.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Subtypes II and IV in Hematopoietic Cell Transplant Recipients. Editor, Roux S. Microbiology Resource Announcements. 2022; 11:e0105321.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Optimized amplification of BK polyomavirus in urine. Journal of Virological Methods. 2022; 299:114319.

Skala, E; Siefert, M; Narkewicz, M; Ziady, A. 218: Plasma proteomics identifies vascular disease, thrombocytopenia, fibrosis, and dysregulation of lipid transport in CF patients 3 years prior to nodular liver ultrasound. Journal of Cystic Fibrosis. 2021; 20:s106-s107.

Siefert, M; Rheiner, S; Brown, H; Lin, S; Johnson, K; Ziady, A. 595: Pharmaceutical modulation of the DNA nanoparticle interactome enhances CFTR gene transfer in vivo. Journal of Cystic Fibrosis. 2021; 20:s283.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Genotypes in Two Patients after Hematopoietic Cell Transplant. Editor, Roux S. Microbiology Resource Announcements. 2021; 10:e01122-e01120.

Gecili, E; Ziady, A; Szczesniak, RD. Forecasting COVID-19 confirmed cases, deaths and recoveries: Revisiting established time series modeling through novel applications for the USA and Italy. Editor, Samy AM. PloS one. 2021; 16:e0244173.

Wolfe, C; Pestian, T; Gecili, E; Su, W; Keogh, RH; Pestian, JP; Seid, M; Diggle, PJ; Ziady, A; Clancy, JP; Grossoehme, DH; Szczesniak, RD; Brokamp, C. Cystic Fibrosis Point of Personalized Detection (CFPOPD): An Interactive Web Application. JMIR Medical Informatics. 2020; 8:e23530.

Sagel, SD; Wagner, BD; Ziady, A; Kelley, T; Clancy, JP; Narvaez-Rivas, M; Pilewski, J; Joseloff, E; Sha, W; Zelnick, L; Setchell, KD R; Heltshe, SL; Muhlebach, MS. Utilizing centralized biorepository samples for biomarkers of cystic fibrosis lung disease severity. Journal of Cystic Fibrosis. 2020; 19:632-640.