Ziady Lab
Publications

Publications

Borcherding, DC; Siefert, ME; Lin, S; Brewington, J; Sadek, H; Clancy, JP; Plafker, SM; Ziady, AG. Clinically-approved CFTR modulators rescue Nrf2 dysfunction in cystic fibrosis airway epithelia. Journal of Clinical Investigation. 2019; 129(8):3448-3463.

Cheng, Y; Doane, TL; Chuang, C-H; Ziady, A; Burda, C. Near infrared light-triggered drug generation and release from gold nanoparticle carriers for photodynamic therapy. Small. 2014; 10(9):1799-1804.

Ziady, AG; Sokolow, A; Shank, S; Corey, D; Myers, R; Plafker, S; Kelley, TJ. Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2012; 302(11):L1221-L1231.

Drumm, ML; Ziady, AG; Davis, PB. Genetic variation and clinical heterogeneity in cystic fibrosis. Annual Review of Pathology: Mechanisms of Disease. 2012; 7:267-282.

Yurek, DM; Fletcher, AM; Mcshane, M; Kowalczyk, TH; Padegimas, L; Weatherspoon, MR; Kaytor, MD; Cooper, MJ; Ziady, AG. DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging. Molecular Imaging. 2011; 10(5):327-339.

Chen, X; Shank, S; Davis, PB; Ziady, AG. Nucleolin-mediated cellular trafficking of DNA nanoparticle is lipid raft and microtubule dependent and can be modulated by glucocorticoid. Molecular Therapy. 2011; 19(1):93-102.

Ko, IK; Ziady, A; Lu, S; Kwon, YJ. Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier. Biomaterials. 2008; 29(28):3872-3881.

Konstan, MW; Davis, PB; Wagener, JS; Hilliard, KA; Stern, RC; Milgram, LJH; Kowalczyk, TH; Hyatt, SL; Fink, TL; Gedeon, CR; Muhammad, O; Ziady, AG; Moen, RC; Cooper, MJ. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Human Gene Therapy. 2004; 15(12):1255-1269.

Ziady, A-G; Gedeon, CR; Miller, T; Quan, W; Payne, JM; Hyatt, SL; Fink, TL; Muhammad, O; Oette, S; Kowalczyk, T; Pasumarthy, MK; Moen, RC; Cooper, MJ; Davis, PB. Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo. Molecular Therapy. 2003; 8(6):936-947.

Ziady, A-G; Kelley, TJ; Milliken, E; Ferkol, T; Davis, PB. Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor. Molecular Therapy. 2002; 5(4):413-419.

Myers, KC; Skala, EJ; Ghandikota, S; Jegga, AG; Mousa, N; Siefert, ME; Lane, A; Reffatto, V; Towe, C; Luebbering, N; Bridgeland, A; Goldfarb, S; Davies, SM; Ziady, AG. Blood proteomics of paediatric bronchiolitis obliterans syndrome after hematopoietic cell transplant. ERJ Open Research. 2025; 00745-02025.

Walder, TA; Meeds, HL; Grimley, MS; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT; Rubinstein, JD. BK polyomavirus genotype IV isolates from virus-specific T-cell therapy recipients. Microbiology Resource Announcements. 2025; 14(10):e0062525.

Walder, TA; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Single-nucleotide polymorphisms within the BK polyomavirus non-coding control region are genotype-associated. Microbiology Spectrum. 2025; 13(8):e0049425.

Potter, A; Sharma, N; Patel, K; Qureshi, MR; Khan, M; Wallace, C; Ziady, A; Ashfaq, A; Moore, C; Hayes, D. Persisting Inflammatory and Fibrotic Gene Signatures Linking Acute Cellular Rejection to Chronic Lung Allograft Dysfunction. American Journal of Transplantation. 2025; 25(8):s823-s824.

Potter, A; Sharma, N; Wallace, C; Ziady, A; Moore, C; Morales, D; Hayes, D. (750) Single Cell Technology Shines LIGHT on Acute Lung Allograft Dysfunction. The Journal of Heart and Lung Transplantation. 2025; 44(4):s355.

Potter, A; Sharma, N; Patel, K; Qureshi, M; Khan, M; Wallace, C; Ziady, A; Morales, D; Hayes, D. (276) Gene Expression Alterations in Lung Allografts with ACR and After Treatment Compared to Never ACR. The Journal of Heart and Lung Transplantation. 2025; 44(4):s140.

Liu, B; Sajiki, Y; Littlefield, N; Hu, Y; Stuart, WD; Sridharan, A; Cui, X; Siefert, ME; Araki, K; Ziady, AG; Shi, D; Whitsett, JA; Maeda, Y. PBAE-PEG-based lipid nanoparticles for lung cell-specific gene delivery. Molecular Therapy. 2025; 33(3):1154-1165.

Cook, E; Langenberg, L; Luebbering, N; Ibrahimova, A; Myers, KC; Sabulski, A; Dandoy, C; Lake, K; Ziady, A; Lane, A; Webster, A; Abdullah, S; Jodele, S; Davies, SM. Oxidative Stress Early After Hematopoietic Stem Cell Transplant. Transplantation and Cellular Therapy. 2025; 31(3):135.e1-135.e10.

Abdullah, S; Sabulski, A; Hudda, Z; Ziady, A; Luebbering, N; Giordullo, L; Odegard, E; Blackard, JT; Kleiboeker, S; Altrich, M; Jodele, S; Seif, AE; Davies, SM; Laskin, BL. Susceptibility to BK polyomavirus-associated hemorrhagic cystitis in children undergoing allogeneic transplant. Haematologica. 2025; 110(2):527-531.

Abdullah, S; Sabulski, A; Hudda, Z; Ziady, AG; Luebbering, N; Langenberg, L; Odegard, E; Blackard, JT; Kleiboeker, S; Jodele, S; Seif, AE; Davies, SM; Laskin, B. Bkpyv Replication Kinetics and Association with Hemorrhagic Cystitis in Pediatric HSCT Recipients. Transplantation and Cellular Therapy. 2025; 31(2):s515-s516.

Amman, AM; Wolfe, V; Piraino, G; Ziady, A; Zingarelli, B. Humanin-G Ameliorates Hemorrhage-Induced Acute Lung Injury in Mice Through AMPKα1-Dependent and -Independent Mechanisms. Biomedicines. 2024; 12(11).

Walder, TA; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Rare BK polyomavirus subtype III detected in hematopoietic cell transplant recipient. Microbiology Resource Announcements. 2024; 13(11):e0067624.

Auld, SC; Sheshadri, A; Alexander-Brett, J; Aschner, Y; Barczak, AK; Basil, MC; Cohen, KA; Dela Cruz, C; Mcgroder, C; Restrepo, MI; Staitieh, BS; Stek, C; Sun, J; Evans, SE. Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society. 2024; 21(9):1219-1237.

Skala, E; Banerjee, R; Siefert, M; Dusa, C; Stevens, C; Hils, B; Bdaiwi, A; Hayes, D; Cleveland, Z; Ziady, A. 846 Plasma proteomics identifies changes in disease-associated pathways in subjects with CF bronchiectasis after elexacaftor/tezacaftor/ivacaftor initiation. Journal of Cystic Fibrosis. 2024; 23:s490.

Siefert, M; Rheiner, S; Ziady, A; Lin, S. 269 Modulating nucleolin trafficking can significantly enhance DNA nanoparticle-mediated gene expression in the lung. Journal of Cystic Fibrosis. 2024; 23:s143.

Chokshi, SM; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Uncommon BK polyomaviruses detected in allogeneic hematopoietic cell transplant recipients. Microbiology Resource Announcements. 2024; 13(6):e0000524.

Chokshi, SM; Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Uncommon BK polyomaviruses detected in allogeneic hematopoietic cell transplant recipients. Microbiology Resource Announcements. 2024; 13(6).

Skala, EJ; Siefert, ME; Potter, AS; Sharma, N; Hayes, D; Ziady, AG. (610) Bronchoalveolar Lavage and Plasma Proteomes Identify Features of Disease That Segregate Lung Transplant Recipients with versus without Bronchiolitis Obliterans Syndrome. The Journal of Heart and Lung Transplantation. 2024; 43(4):s297.

Siefert, ME; Skala, EJ; Potter, AS; Hayes, D; Ziady, A. (1358) Plasma and Bronchoalveolar Fluid Proteomes Identify Similar Pathways Associated with Allograft Dysfunction in Individual LTx Recipients with Different Underlying Conditions. The Journal of Heart and Lung Transplantation. 2024; 43(4):s625-s626.

Potter, A; Wikenheiser-Brokamp, K; Hildeman, D; Sharma, N; Gu, M; Patel, K; Qureshi, M; Khan, MM; Wallace, C; Ziady, A; Hayes, D. (601) Decoding T Cell Clonal Dynamics in Acute Lung Rejection. The Journal of Heart and Lung Transplantation. 2024; 43(4):s293.

Koo, J; Langenberg, L; Luebbering, N; Strecker, L; Abdullah, S; Carusone, E; Deavy, M; Hoerth, C; Miller, G; Turner, D; Ziady, AG; Myers, KC; Jodele, S; Davies, SM. Ceramides Are Elevated in Transplant-Associated Thrombotic Microangiopathy in Hematopoietic Stem Cell Transplant Recipients and Are a Druggable Target for Prophylaxis. Transplantation and Cellular Therapy. 2024; 30(2):s17-s18.

Sabulski, A; Abdullah, S; Luebbering, N; Aunins, B; Castillo, C; Lake, K; Duell, A; Strecker, L; Langenberg, L; Broomhead, W; Dandoy, CE; Laskin, BL; Jodele, S; Davies, SM. Mechanisms of endothelial injury and transplant-associated thrombotic microangiopathy in tandem autologous hematopoietic stem cell transplant for neuroblastoma. Haematologica. 2023; 108(12):3449-3453.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Diversity After Hematopoietic Stem Cell Transplantation. Journal of Infectious Diseases. 2023; 228(9):1208-1218.

Koo, J; Ziady, AG; Reynaud, D; Abdullah, S; Luebbering, N; Kahn, S; Langenberg, L; Strecker, L; Lake, K; Dandoy, CE; Siefert, ME; Skala, E; Jodele, S; Davies, SM. Increased Body Mass Index Augments Endothelial Injury and Clinical Outcomes after Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy. 2023; 29(11):704.e1-704.e8.

Koh, W; Zang, H; Ollberding, NJ; Ziady, A; Hayes, D. Extracorporeal membrane oxygenation bridge to pediatric lung transplantation: Modern era analysis. Pediatric Transplantation. 2023; 27(6):e14570.

Guzman-Gomez, A; Ahmed, HF; Dani, A; Zafar, F; Lehenbauer, DG; Potter, AS; Morales, DLS; Ziady, AG; Hayes, D. Center volume effect on acute cellular rejection and outcomes in pediatric lung transplant recipients. The Journal of Heart and Lung Transplantation. 2023; 42(8):1030-1039.

Wagner, ML; Ammann, A; Piraino, G; Wolfe, V; O'connor, M; Lahni, P; Ziady, A; Zingarelli, B. PROTECTIVE EFFECTS OF HUMANIN-G IN HEMORRHAGIC SHOCK IN FEMALE MICE VIA AMPKα1-INDEPENDENT MECHANISMS. Shock. 2023; 60(1):64-74.

Pradhan, A; Che, L; Ustiyan, V; Reza, AA; Pek, NM; Zhang, Y; Alber, AB; Kalin, TR; Wambach, JA; Gu, M; Kotton, DN; Siefert, ME; Ziady, AG; Kalin, TV; Kalinichenko, VV. Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2023; 207(8):1042-1054.

Guzman-Gomez, A; Skala, E; Dani, A; Sharma, N; Ziady, A; Hayes, D. Sex and Sex Hormones Matter in Lung Transplant Outcomes. The Journal of Heart and Lung Transplantation. 2023; 42(4):s141.

Hayes, D; Dani, A; Guzman-Gomez, A; Zafar, F; Morales, DLS; Ziady, AG. Changing racial and ethnic differences for lung transplantation in cystic fibrosis. Pediatric Transplantation. 2023; 27(1):e14404.

Sabulski, A; Siefert, ME; Skala, E; Abdullah, S; Luebbering, N; Myers, K; Odegard, E; Blackard, JT; Seif, AE; Jodele, S; Davies, SM; Laskin, B; Ziady, A. 77 Proteomic Analyses Reveal Molecular Connections That Support the Clinical Association of Cystitis with Thrombotic Microangiopathy in Pediatric Transplant Recipients. Transplantation and Cellular Therapy. 2023; 29(2):s64-s65.

Zhang, G; Odegard, E; Sabulski, A; Jodele, S; Ziady, A; Seif, AE; Davies, SM; Laskin, B; Blackard, JT. 441 Evolution of BK Polyomavirus in Immunocompromised Pediatric Patients. Transplantation and Cellular Therapy. 2023; 29(2):s333-s334.

Odegard, E; Meeds, H; Kleiboeker, S; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, B; Blackard, JT. 429 BK Polyomavirus after Pediatric Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy. 2023; 29(2):s324-s325.

Koo, J; Reynaud, D; Ziady, A; Kahn, S; Abdullah, S; Luebbering, N; Strecker, L; Lake, KE; Giordullo, L; Ibrahimova, A; Good, S; Dandoy, CE; Myers, K; Jodele, S; Davies, SM. 166 Reduced Sphingosine-1-Phosphate Leads to Hypoxemia and Lung Injury after Hematopoietic Stem Cell Transplant. Transplantation and Cellular Therapy. 2023; 29(2):s134.

Sabulski, A; Abdullah, S; Luebbering, N; Aunins, B; Castillo, C; Lake, K; Duell, A; Strecker, L; Giordullo, L; Broomhead, W; Dandoy, CE; Laskin, BL; Jodele, S; Davies, SM. Circulating endothelial cells and the study of vascular injury in children undergoing hematopoietic stem cell transplant. Haematologica. 2022; 107(12):2950-2954.

Schwarzenberg, SJ; Palermo, JJ; Ye, W; Huang, S; Magee, JC; Alazraki, A; Freeman, AJ; Harned, R; Karmazyn, B; Karnsakul, W; Stoll, J; Towbin, AJ; Narkewicz, MR; Alonso, EM. Health-related Quality of Life in a Prospective Study of Ultrasound to Detect Cystic Fibrosis-related Liver Disease in Children. Journal of Pediatric Gastroenterology and Nutrition. 2022; 75(5):635-642.

Siefert, M; Rheiner, S; Adams, M; Hayes, H; Lin, S; Ziady, A. 591 Modulation of the deoxyribonucleic acid nanoparticle interactome enhances cystic fibrosis transmembrane conductance regulator gene transfer in a cystic fibrosis mouse model. Journal of Cystic Fibrosis. 2022; 21:s328.

Dani, A; Zafar, F; Morales, D; Ziady, A; Hayes, D. 147 Lung transplantation waitlist disparities for children with cystic fibrosis. Journal of Cystic Fibrosis. 2022; 21:s86.

Skala, E; Hayes, D; Ziady, A. 174 Identification of physiological characteristics at baseline and 1 and 6 months that segregate lung function response to ivacaftor using proteomic analysis. Journal of Cystic Fibrosis. 2022; 21:s101-s102.

Skala, E; Sharma, N; Hayes, D; Ziady, A. 143 Bronchoalveolar lavage proteome identifies pathways of disease that segregate lung transplant recipients with and without bronchiolitis obliterans syndrome. Journal of Cystic Fibrosis. 2022; 21:s84.

Hayes, D; Melicoff-Portillo, E; Ziady, AG. Selection of lung transplant candidates: A pediatric perspective on the International Society for Heart and Lung Transplantation consensus document. The Journal of Heart and Lung Transplantation. 2022; 41(7):998-999.

Hayes, D; Shukla, RK; Cheng, Y; Gecili, E; Merling, MR; Szczesniak, RD; Ziady, AG; Woods, JC; Hall-Stoodley, L; Liyanage, NP; Robinson, RT. Tissue-localized immune responses in people with cystic fibrosis and respiratory nontuberculous mycobacteria infection. JCI Insight. 2022; 7(12).

Gecili, E; Sivaganesan, S; Asar, O; Clancy, JP; Ziady, A; Szczesniak, RD. Bayesian regularization for a nonstationary Gaussian linear mixed effects model. Statistics in Medicine. 2022; 41(4):681-697.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Subtypes II and IV in Hematopoietic Cell Transplant Recipients. Microbiology Resource Announcements. 2022; 11(1):e0105321.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Seif, AE; Davies, SM; Laskin, BL; Blackard, JT. Optimized amplification of BK polyomavirus in urine. Journal of Virological Methods. 2022; 299:114319.

Hudock, KM; Collins, MS; Imbrogno, MA; Kramer, EL; Brewington, JJ; Ziady, A; Zhang, N; Snowball, J; Xu, Y; Carey, BC; Gollomp, K; Mangalmurti, N; Trapnell, BC; Clancy, JP. Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in Immunology. 2022; 13:1023553.

Skala, E; Siefert, M; Network, CFLD; Narkewicz, M; Ziady, A. 218: Plasma proteomics identifies vascular disease, thrombocytopenia, fibrosis, and dysregulation of lipid transport in CF patients 3 years prior to nodular liver ultrasound. Journal of Cystic Fibrosis. 2021; 20:s106-s107.

Siefert, M; Rheiner, S; Brown, H; Lin, S; Johnson, K; Ziady, A. 595: Pharmaceutical modulation of the DNA nanoparticle interactome enhances CFTR gene transfer in vivo. Journal of Cystic Fibrosis. 2021; 20:s283.

Odegard, EA; Meeds, HL; Kleiboeker, SB; Ziady, A; Sabulski, A; Jodele, S; Davies, SM; Laskin, BL; Blackard, JT. BK Polyomavirus Genotypes in Two Patients after Hematopoietic Cell Transplant. Microbiology Resource Announcements. 2021; 10(2).

Gecili, E; Ziady, A; Szczesniak, RD. Forecasting COVID-19 confirmed cases, deaths and recoveries: Revisiting established time series modeling through novel applications for the USA and Italy. PLoS ONE. 2021; 16(1):e0244173.

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